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Non-Darwinian Evolution (paper)
"Non-Darwinian Evolution" is a scientific paper written by Jack Lester King and Thomas H. Jukes and published in 1969. It is credited, along with Motoo Kimura's 1968 paper "Evolutionary Rate at the Molecular Level", with proposing what became known as the neutral theory of molecular evolution. The paper brings together a wide variety of evidence, ranging from protein sequence comparisons to studies of the Treffers mutator gene in '' E. coli'' to analysis of the genetic code to comparative immunology, to argue that most protein evolution is due to neutral mutations and genetic drift. It was published in the journal ''Science'' on May 16, 1969. The idea of evolution at the molecular level being driven by the random processes of mutation and genetic drift, largely independent from natural selection, was controversial at the time; the provocative title further emphasized the break with mainstream evolutionary thought, which was dominated by the synthetic theory of evolution, often re ...
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Jack Lester King
Jack Lester King (March 9, 1934 – June 29, 1983) was an American evolutionary biologist best known for co-authoring (with Thomas H. Jukes) a seminal paper on the neutral theory of molecular evolution, "Non-Darwinian Evolution". King was born in Oakland, California and received both undergraduate and doctoral training at the University of California, Berkeley, earning a Ph.D. in Zoology in 1963. From 1963 to 1969, he remained at UC Berkeley as a postdoctoral fellow in population genetics, then independent researcher in biophysics, at the Donner Laboratory. In 1969, King became a professor at University of California, Santa Barbara."Jack Lester King 1934–1983 Associate Editor of the ''Journal of Molecular Evolution'' October 1971–June 1983", in ''Journal of Molecular Evolution'', Vol. 19, No. 5 (1983), pp. 307-308 King and Jukes' "Non-Darwinian Evolution", published in ''Science'' in 1969 shortly after Motoo Kimura first mooted the neutral theory, brought together a va ...
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Emil L
Emil or Emile may refer to: Literature *'' Emile, or On Education'' (1762), a treatise on education by Jean-Jacques Rousseau * ''Émile'' (novel) (1827), an autobiographical novel based on Émile de Girardin's early life *'' Emil and the Detectives'' (1929), a children's novel *"Emil", nickname of the Kurt Maschler Award for integrated text and illustration (1982–1999) *'' Emil i Lönneberga'', a series of children's novels by Astrid Lindgren Military * Emil (tank), a Swedish tank developed in the 1950s * Sturer Emil, a German tank destroyer People * Emil (given name), including a list of people with the given name ''Emil'' or ''Emile'' * Aquila Emil (died 2011), Papua New Guinean rugby league footballer Other * ''Emile'' (film), a Canadian film made in 2003 by Carl Bessai * Emil (river), in China and Kazakhstan See also * * * Aemilius (other) *Emilio (other) *Emílio (other) *Emilios (other) Emilios, or Aimilios, (Greek: Αιμίλιο ...
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Evolutionary Biology Literature
Evolution is change in the heritable characteristics of biological populations over successive generations. These characteristics are the expressions of genes, which are passed on from parent to offspring during reproduction. Variation tends to exist within any given population as a result of genetic mutation and recombination. Evolution occurs when evolutionary processes such as natural selection (including sexual selection) and genetic drift act on this variation, resulting in certain characteristics becoming more common or more rare within a population. The evolutionary pressures that determine whether a characteristic is common or rare within a population constantly change, resulting in a change in heritable characteristics arising over successive generations. It is this process of evolution that has given rise to biodiversity at every level of biological organisation, including the levels of species, individual organisms, and molecules. The theory of evolution by na ...
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History Of Evolutionary Biology
History (derived ) is the systematic study and the documentation of the human activity. The time period of event before the invention of writing systems is considered prehistory. "History" is an umbrella term comprising past events as well as the memory, discovery, collection, organization, presentation, and interpretation of these events. Historians seek knowledge of the past using historical sources such as written documents, oral accounts, art and material artifacts, and ecological markers. History is not complete and still has debatable mysteries. History is also an academic discipline which uses narrative to describe, examine, question, and analyze past events, and investigate their patterns of cause and effect. Historians often debate which narrative best explains an event, as well as the significance of different causes and effects. Historians also debate the nature of history as an end in itself, as well as its usefulness to give perspective on the problems of the p ...
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Biology Papers
Biology is the science, scientific study of life. It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. For instance, all organisms are made up of Cell (biology), cells that process hereditary information encoded in genes, which can be transmitted to future generations. Another major theme is evolution, which explains the unity and diversity of life. Metabolism, Energy processing is also important to life as it allows organisms to Animal locomotion, move, grow, and reproduce. Finally, all organisms are able to regulate their own internal environments. Biologists are able to study life at multiple Biological organisation, levels of organization, from the molecular biology of a cell to the anatomy and physiology of plants and animals, and evolution of populations.Based on definition from: Hence, there are multiple Outline of biology#Branches, subdisciplines within biology, each defined by the nature of thei ...
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1969 Documents
This year is notable for Apollo 11's first landing on the moon. Events January * January 4 – The Government of Spain hands over Ifni to Morocco. * January 5 **Ariana Afghan Airlines Flight 701 crashes into a house on its approach to London's Gatwick Airport, killing 50 of the 62 people on board and two of the home's occupants. * January 14 – An explosion aboard the aircraft carrier USS ''Enterprise'' near Hawaii kills 27 and injures 314. * January 19 – End of the siege of the University of Tokyo, marking the beginning of the end for the 1968–69 Japanese university protests. * January 20 – Richard Nixon is sworn in as the 37th President of the United States. * January 22 – An assassination attempt is carried out on Soviet leader Leonid Brezhnev by deserter Viktor Ilyin. One person is killed, several are injured. Brezhnev escaped unharmed. * January 27 ** Fourteen men, 9 of them Jews, are executed in Baghdad for spying for Israel. ** Reveren ...
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1969 In Biology
This year is notable for Apollo 11's first landing on the moon. Events January * January 4 – The Government of Spain hands over Ifni to Morocco. * January 5 **Ariana Afghan Airlines Flight 701 crashes into a house on its approach to London's Gatwick Airport, killing 50 of the 62 people on board and two of the home's occupants. * January 14 – An explosion aboard the aircraft carrier USS Enterprise (CVN-65), USS ''Enterprise'' near Hawaii kills 27 and injures 314. * January 19 – End of the siege of the University of Tokyo, marking the beginning of the end for the 1968–69 Japanese university protests. * January 20 – Richard Nixon is First inauguration of Richard Nixon, sworn in as the 37th President of the United States. * January 22 – Attempted assassination of Leonid Brezhnev, An assassination attempt is carried out on Soviet leader Leonid Brezhnev by deserter Viktor Ilyin. One person is killed, several are injured. Leonid Brezhnev, Brezhnev es ...
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History Of Molecular Evolution
The history of molecular evolution starts in the early 20th century with "comparative biochemistry", but the field of molecular evolution came into its own in the 1960s and 1970s, following the rise of molecular biology. The advent of protein sequencing allowed molecular biologists to create phylogenies based on sequence comparison, and to use the differences between homologous sequences as a molecular clock to estimate the time since the last common ancestor. In the late 1960s, the neutral theory of molecular evolution provided a theoretical basis for the molecular clock, though both the clock and the neutral theory were controversial, since most evolutionary biologists held strongly to panselectionism, with natural selection as the only important cause of evolutionary change. After the 1970s, nucleic acid sequencing allowed molecular evolution to reach beyond proteins to highly conserved ribosomal RNA sequences, the foundation of a reconceptualization of the early history of life. ...
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History Of Evolutionary Thought
Evolutionary thought, the recognition that species change over time and the perceived understanding of how such processes work, has roots in antiquity—in the ideas of the ancient Greeks, Romans, Chinese, Church Fathers as well as in medieval Islamic science. With the beginnings of modern biological taxonomy in the late 17th century, two opposed ideas influenced Western biological thinking: essentialism, the belief that every species has essential characteristics that are unalterable, a concept which had developed from medieval Aristotelian metaphysics, and that fit well with natural theology; and the development of the new anti-Aristotelian approach to modern science: as the Enlightenment progressed, evolutionary cosmology and the mechanical philosophy spread from the physical sciences to natural history. Naturalists began to focus on the variability of species; the emergence of palaeontology with the concept of extinction further undermined static views of nature ...
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Neutralist/selectionist Controversy
The history of molecular evolution starts in the early 20th century with "comparative biochemistry", but the field of molecular evolution came into its own in the 1960s and 1970s, following the rise of molecular biology. The advent of protein sequencing allowed molecular biologists to create phylogenies based on sequence comparison, and to use the differences between homologous sequences as a molecular clock to estimate the time since the last common ancestor. In the late 1960s, the neutral theory of molecular evolution provided a theoretical basis for the molecular clock, though both the clock and the neutral theory were controversial, since most evolutionary biologists held strongly to panselectionism, with natural selection as the only important cause of evolutionary change. After the 1970s, nucleic acid sequencing allowed molecular evolution to reach beyond proteins to highly conserved ribosomal RNA sequences, the foundation of a reconceptualization of the early history of life. ...
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Rollin Richmond
Rollin Charles Richmond was the president of Humboldt State University in Arcata, California from May 2002 to July 2014. Before taking that position he was provost and genetics professor at Iowa State University, leading research on the genetic mechanisms of fruit flies evolution and effects of cocaine on Drosophila. He has also served in various positions at the State University of New York at Stony Brook, the University of South Florida, and Indiana University. The November 7, 2007 issue of the Humboldt State University weekly student-run paper, ''The Lumberjack'', reported that the Academic Senate at HSU voted by 56% to issue a vote of no confidence A motion of no confidence, also variously called a vote of no confidence, no-confidence motion, motion of confidence, or vote of confidence, is a statement or vote about whether a person in a position of responsibility like in government or mana ... in Rollin Richmond's leadership. Under his leadership Humboldt State University ...
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Bryan Clarke
Bryan Campbell Clarke (24 June 1932 – 27 February 2014) was a British Professor of genetics, latterly emeritus at the University of Nottingham. Clarke is particularly noted for his work on apostatic selection (which is a term he coined in 1962) and other forms of frequency-dependent selection, and work on polymorphism in snails, much of it done during the 1960s. Later, he studied molecular evolution. He made the case for natural selection as an important factor in the maintenance of molecular variation, and in driving evolutionary changes in molecules through time. In doing so, he questioned the over-riding importance of random genetic drift advocated by King, Jukes, and Kimura. With Professor James J Murray Jnr (University of Virginia), he carried out an extensive series of studies on speciation in land snails of the genus '' Partula'' inhabiting the volcanic islands of the Eastern Pacific. These studies helped illuminate the genetic changes that take place during the o ...
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