Neuronal Memory Allocation
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Neuronal Memory Allocation
Memory allocation is a process that determines which specific synapses and neurons in a neural network will store a given memory.Won, J. and A.J. Silva, Molecular and cellular mechanisms of memory allocation in neuronetworks. Neurobiol Learn Mem, 2007. Silva, A.J., Zhou, Y, Rogerson, T, Shobe, J and Balaji, J. Molecular and Cellular Approaches to Memory Allocation in Neural Circuits. Science, Oct 16 2009;326(5951):391-5. .Rogerson, T. et al. Synaptic tagging during memory allocation. Nature Rev. Neurosci 15, 157-169 (2014) Although multiple neurons can receive a stimulus, only a subset of the neurons will induce the necessary plasticity for memory encoding. The selection of this subset of neurons is termed Neuronal memory allocation#neuronal allocation, neuronal allocation. Similarly, multiple synapses can be activated by a given set of inputs, but specific mechanisms determine which synapses actually go on to encode the memory, and this process is referred to as Neuronal memory al ...
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Synapses
In the nervous system, a synapse is a structure that allows a neuron (or nerve cell) to pass an electrical or chemical signal to another neuron or a target effector cell. Synapses can be classified as either chemical or electrical, depending on the mechanism of signal transmission between neurons. In the case of electrical synapses, neurons are coupled bidirectionally with each other through gap junctions and have a connected cytoplasmic milieu. These types of synapses are known to produce synchronous network activity in the brain, but can also result in complicated, chaotic network level dynamics. Therefore, signal directionality cannot always be defined across electrical synapses. Chemical synapses, on the other hand, communicate through neurotransmitters released from the presynaptic neuron into the synaptic cleft. Upon release, these neurotransmitters bind to specific receptors on the postsynaptic membrane, inducing an electrical or chemical response in the target neuron. T ...
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