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Nervine
Nervine was a patent medicine tonic with sedative effects introduced in 1884 by Dr. Miles Medical Company (later Miles Laboratories which was absorbed into Bayer). It is a cognate of 'Nerve', and the implication was that the material worked to calm nervousness. Formulation One form of Nervine was formulated with the primary active ingredients sodium bromide, ammonium bromide, and potassium bromide, combined with sodium bicarbonate and citric acid in an effervescent tablet.{{cite web, url= https://americanhistory.si.edu/collections/search/object/nmah_1339050 , title= Miles Nervine Effervescent Tablets, website= National Museum of American History, date= c. 1940, access-date= April 24, 2022 Modern appropriation of term In the late 20th and early 21st century, promulgators of alternative medicine and herbalism have begun to use the term Nervine as an adjective. This is not a term used by mainstream medicine, where anxiolytic An anxiolytic (; also antipanic or antianxiety ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Miles Laboratories
Miles Laboratories was founded as the Dr. Miles Medical Company in Elkhart, Indiana, in 1884 by Dr. Franklin Lawrence Miles, a specialist in the treatment of eye and ear disorders, with an interest in the connection of the nervous system to overall health. The company is known for inventing products such as Alka-Selzer and One-A-Day vitamins. Miles operated as an independent firm from 1884 until 1979 and as a wholly owned subsidiary of Bayer AG from 1979 until 1995. At the company's peak in the 1960s and 1970s, it employed 3,300 people and produced more than two dozen products. In 1995, it was consolidated into the parent corporation. History By 1890, the sales success of his patent medicine tonic, "Dr. Miles Restorative Nervine," in treating "nervous" ailments (including "nervousness or nervous exhaustion, sleeplessness, hysteria, headache, neuralgia, backache, pain, epilepsy, spasms, fits, and St. Vitus' dance") led him to develop a mail order medicine business. Miles ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Patent Medicine
A patent medicine, sometimes called a proprietary medicine, is an over-the-counter (nonprescription) medicine or medicinal preparation that is typically protected and advertised by a trademark and trade name (and sometimes a patent) and claimed to be effective against minor disorders and symptoms. Its contents are typically incompletely disclosed. Antiseptics, analgesics, some sedatives, laxatives, and antacids, cold and cough medicines, and various skin preparations are included in the group. The safety and effectiveness of patent medicines and their sale is controlled and regulated by the Food and Drug Administration in the United States and corresponding authorities in other countries.https://www.merriam-webster.com/dictionary/patent%20medicine The term is sometimes still used to describe quack remedies of unproven effectiveness and questionable safety sold especially by peddlers in past centuries, who often also called them elixirs, tonics, or liniments. Current examples o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bayer
Bayer AG (, commonly pronounced ; ) is a German multinational corporation, multinational pharmaceutical and biotechnology company and one of the largest pharmaceutical companies in the world. Headquartered in Leverkusen, Bayer's areas of business include pharmaceuticals; consumer healthcare products, agricultural chemicals, seeds and biotechnology products. The company is a component of the Euro Stoxx 50 stock market index. Bayer was founded in 1863 in Barmen as a partnership between dye salesman Friedrich Bayer and dyer Friedrich Weskott. As was common in this era, the company was established as a dyestuffs producer. The versatility of aniline chemistry led Bayer to expand their business into other areas, and in 1899 Bayer launched the compound acetylsalicylic acid under the trademarked name Aspirin. In 1904 Bayer received a trademark for the "Bayer Cross" logo, which was subsequently stamped onto each aspirin tablet, creating an iconic product that is still sold by Bayer. Ot ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sodium Bromide
Sodium bromide is an inorganic compound with the formula Na Br. It is a high-melting white, crystalline solid that resembles sodium chloride. It is a widely used source of the bromide ion and has many applications.Michael J. Dagani, Henry J. Barda, Theodore J. Benya, David C. Sanders "Bromine Compounds" in ''Ullmann's Encyclopedia of Industrial Chemistry'' Wiley-VCH, Weinheim, 2000. Synthesis, structure, reactions NaBr crystallizes in the same cubic motif as NaCl, NaF and NaI. The anhydrous salt crystallizes above 50.7 °C. Dihydrate salts (NaBr·2H2O) crystallize out of water solution below 50.7 °C. NaBr is produced by treating sodium hydroxide with hydrogen bromide. Sodium bromide can be used as a source of the chemical element bromine. This can be accomplished by treating an aqueous solution of NaBr with chlorine gas: :2 NaBr + Cl2 → Br2 + 2 NaCl Applications Sodium bromide is the most useful inorganic bromide in industry. It is also used as a catalyst in T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ammonium Bromide
Ammonium bromide, NH4Br, is the ammonium salt of hydrobromic acid. The chemical crystallizes in colorless prisms, possessing a saline taste; it sublimes on heating and is easily soluble in water. On exposure to air it gradually assumes a yellow color because of the oxidation of traces of bromide (Br−) to bromine (Br2). Preparation Ammonium bromide can be prepared by the direct action of hydrogen bromide on ammonia. : NH3 + HBr → NH4Br It can also be prepared by the reaction of ammonia with iron(II) bromide or iron(III) bromide, which may be obtained by passing aqueous bromine solution over iron filings. : 2 NH3 + FeBr2 + 2 H2O → 2 NH4Br + Fe(OH)2 Reactions Ammonium bromide is a weak acid with a pKa of ~5 in water. It is an acid salt because the ammonium ion hydrolyzes slightly in water. Ammonium Bromide is strong electrolyte when put in water: :NH4Br(s) → NH4+(aq) + Br−(aq) Ammonium bromide decomposes to ammonia and hydrogen bromide when heated at elevated tempe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Potassium Bromide
Potassium bromide ( K Br) is a salt, widely used as an anticonvulsant and a sedative in the late 19th and early 20th centuries, with over-the-counter use extending to 1975 in the US. Its action is due to the bromide ion (sodium bromide is equally effective). Potassium bromide is used as a veterinary drug, as an antiepileptic medication for dogs. Under standard conditions, potassium bromide is a white crystalline powder. It is freely soluble in water; it is not soluble in acetonitrile. In a dilute aqueous solution, potassium bromide tastes sweet, at higher concentrations it tastes bitter, and tastes salty when the concentration is even higher. These effects are mainly due to the properties of the potassium ion—sodium bromide tastes salty at any concentration. In high concentration, potassium bromide strongly irritates the gastric mucous membrane, causing nausea and sometimes vomiting (a typical effect of all soluble potassium salts). Chemical properties Potassium bromide, a typ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sodium Bicarbonate
Sodium bicarbonate (IUPAC name: sodium hydrogencarbonate), commonly known as baking soda or bicarbonate of soda, is a chemical compound with the formula NaHCO3. It is a salt composed of a sodium cation ( Na+) and a bicarbonate anion ( HCO3−). Sodium bicarbonate is a white solid that is crystalline, but often appears as a fine powder. It has a slightly salty, alkaline taste resembling that of washing soda (sodium carbonate). The natural mineral form is nahcolite. It is a component of the mineral natron and is found dissolved in many mineral springs. Nomenclature Because it has long been known and widely used, the salt has many different names such as baking soda, bread soda, cooking soda, and bicarbonate of soda and can often be found near baking powder in stores. The term ''baking soda'' is more common in the United States, while ''bicarbonate of soda'' is more common in Australia, United Kingdom and Ireland. and in many northern/central European countries it is called ''Na ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Citric Acid
Citric acid is an organic compound with the chemical formula HOC(CO2H)(CH2CO2H)2. It is a colorless weak organic acid. It occurs naturally in citrus fruits. In biochemistry, it is an intermediate in the citric acid cycle, which occurs in the metabolism of all aerobic organisms. More than two million tons of citric acid are manufactured every year. It is used widely as an acidifier, as a flavoring, and a chelating agent. A citrate is a derivative of citric acid; that is, the salts, esters, and the polyatomic anion found in solution. An example of the former, a salt is trisodium citrate; an ester is triethyl citrate. When part of a salt, the formula of the citrate anion is written as or . Natural occurrence and industrial production Citric acid occurs in a variety of fruits and vegetables, most notably citrus fruits. Lemons and limes have particularly high concentrations of the acid; it can constitute as much as 8% of the dry weight of these fruits (about 47 g/L in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alternative Medicine
Alternative medicine is any practice that aims to achieve the healing effects of medicine despite lacking biological plausibility, testability, repeatability, or evidence from clinical trials. Complementary medicine (CM), complementary and alternative medicine (CAM), integrated medicine or integrative medicine (IM), and holistic medicine attempt to combine alternative practices with those of mainstream medicine. Alternative therapies share in common that they reside outside of medical science and instead rely on pseudoscience. Traditional practices become "alternative" when used outside their original settings and without proper scientific explanation and evidence. Frequently used derogatory terms for relevant practices are ''new age'' or ''pseudo-'' medicine, with little distinction from quackery. Some alternative practices are based on theories that contradict the established science of how the human body works; others resort to the supernatural or superstitious to explain ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Herbalism
Herbal medicine (also herbalism) is the study of pharmacognosy and the use of medicinal plants, which are a basis of traditional medicine. With worldwide research into pharmacology, some herbal medicines have been translated into modern remedies, such as the anti-malarial group of drugs called artemisinin isolated from '' Artemisia annua'', a herb that was known in Chinese medicine to treat fever. There is limited scientific evidence for the safety and efficacy of plants used in 21st century herbalism, which generally does not provide standards for purity or dosage. The scope of herbal medicine commonly includes fungal and bee products, as well as minerals, shells and certain animal parts. Herbal medicine is also called phytomedicine or phytotherapy. Paraherbalism describes alternative and pseudoscientific practices of using unrefined plant or animal extracts as unproven medicines or health-promoting agents. Paraherbalism relies on the belief that preserving various ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anxiolytic
An anxiolytic (; also antipanic or antianxiety agent) is a medication or other intervention that reduces anxiety. This effect is in contrast to anxiogenic agents which increase anxiety. Anxiolytic medications are used for the treatment of anxiety disorders and their related psychological and physical symptoms. Nature of anxiety Anxiety is a naturally-occurring emotion and an innate response of the body to the environmental stimuli. Mild to moderate anxiety would increase level of performance. However, when anxiety levels exceed the tolerability of a person, anxiety disorders may occur. People with anxiety disorders can exhibit fear responses such as defensive behaviors, high levels of alertness and negative emotions, without external stimuli which induce anxiety within an individual. Those with anxiety disorders are also often found to have concurrent psychological disorders, most commonly depression. Anxiety disorders are divided into 6 types in clinical recognition. They are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bromide
A bromide ion is the negatively charged form (Br−) of the element bromine, a member of the halogens group on the periodic table. Most bromides are colorless. Bromides have many practical roles, being found in anticonvulsants, flame-retardant materials, and cell stains. Although uncommon, chronic toxicity from bromide can result in bromism, a syndrome with multiple neurological symptoms. Bromide toxicity can also cause a type of skin eruption, see potassium bromide. The bromide ion has an ionic radius of 196 pm. Natural occurrence Bromide is present in typical seawater (35 PSU) with a concentration of around 65 mg/L, which is about 0.2% of all dissolved salts. Seafood and deep sea plants generally have higher levels than land-derived foods. Bromargyrite—natural, crystalline silver bromide—is the most common bromide mineral known but is still very rare. In addition to silver, bromine is also in minerals combined with mercury and copper. Formation and react ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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