Naval Medical Research Unit South
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Naval Medical Research Unit South
Naval Medical Research Unit SOUTH , formerly known as Naval Medical Research Unit Six, is a biomedical research laboratory of the U.S. Navy located in Lima, Peru. It is the only U.S. military command located in South America. Its mission is to identify infectious disease threats of military and public health importance and to develop and evaluate interventions and products to mitigate those threats. NAMRU SOUTH consists of of laboratory and office space in Lima and 5000 square feet of lab space in Iquitos, Peru. The Lima facility includes Biosafety Level 3 (BSL-3) facilities, while the other two laboratories are only biosafety level 2 rated. The Lima facility also contains a vivarium for animal research that is Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC) certified. Mission Implementation of NAMRU SOUTH’s mission is via threefold means: # to investigate prophylactic agents such as vaccines and pharmaceuticals against trop ...
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United States Of America
The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territories, nine Minor Outlying Islands, and 326 Indian reservations. The United States is also in free association with three Pacific Island sovereign states: the Federated States of Micronesia, the Marshall Islands, and the Republic of Palau. It is the world's third-largest country by both land and total area. It shares land borders with Canada to its north and with Mexico to its south and has maritime borders with the Bahamas, Cuba, Russia, and other nations. With a population of over 333 million, it is the most populous country in the Americas and the third most populous in the world. The national capital of the United States is Washington, D.C. and its most populous city and principal financial center is New York City. Paleo ...
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Brucella Melitensis
''Brucella melitensis'' is a Gram-negative coccobacillus bacterium from the Brucellaceae family. The bacterium causes ovine brucellosis, along with '' Brucella ovis''. It affects primarily sheep and goats, but cases have also been observed in cattle, yaks, water buffalo, Bactrian and dromedary camels, alpacas, dogs, horses and pigs. Humans can become infected if they have contact with an infected animal or its byproducts. Animals acquire ''B. melitensis'' by venereal transmission and contact with the placenta, fetus, fetal fluids, and vaginal discharges from infected animals. The organism is found in blood, urine, milk, and semen. It is zoonotic, unlike ''B. ovis'', causing Malta fever or localized brucellosis in humans. Clinical manifestation The bacterium causes severe inflammation of the epididymis, with formation of spermatocoeles and fibrinous adhesions. This disease is known as ovine brucellosis, and is a reportable disease in the USA. In goats and sheep, ''B. melit ...
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Pentamidine
Pentamidine is an antimicrobial medication used to treat African trypanosomiasis, leishmaniasis, ''Balamuthia'' infections, babesiosis, and to prevent and treat pneumocystis pneumonia (PCP) in people with poor immune function. In African trypanosomiasis it is used for early disease before central nervous system involvement, as a second line option to suramin. It is an option for both visceral leishmaniasis and cutaneous leishmaniasis. Pentamidine can be given by injection into a vein or muscle or by inhalation. Common side effects of the injectable form include low blood sugar, pain at the site of injection, nausea, vomiting, low blood pressure, and kidney problems. Common side effects of the inhaled form include wheezing, cough, and nausea. It is unclear if doses should be changed in those with kidney or liver problems. Pentamidine is not recommended in early pregnancy but may be used in later pregnancy. Its safety during breastfeeding is unclear. Pentamidine is in the aromatic ...
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Rickettsia
''Rickettsia'' is a genus of nonmotile, gram-negative, nonspore-forming, highly pleomorphic bacteria that may occur in the forms of cocci (0.1 μm in diameter), bacilli (1–4 μm long), or threads (up to about 10 μm long). The term "rickettsia" has nothing to do with rickets (which is a deficiency disease resulting from lack of vitamin D); the bacterial genus ''Rickettsia'' instead was named after Howard Taylor Ricketts, in honor of his pioneering work on tick-borne spotted fever. Properly, ''Rickettsia'' is the name of a single genus, but the informal term "rickettsia", plural "rickettsias", usually not capitalised, commonly applies to any members of the order Rickettsiales. Being obligate intracellular bacteria, rickettsias depend on entry, growth, and replication within the cytoplasm of living eukaryotic host cells (typically endothelial cells). Accordingly, ''Rickettsia'' species cannot grow in artificial nutrient culture; they must be grown either in tissue or embryo ...
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Hepatitis
Hepatitis is inflammation of the liver tissue. Some people or animals with hepatitis have no symptoms, whereas others develop yellow discoloration of the skin and whites of the eyes (jaundice), poor appetite, vomiting, tiredness, abdominal pain, and diarrhea. Hepatitis is ''acute'' if it resolves within six months, and '' chronic'' if it lasts longer than six months. Acute hepatitis can resolve on its own, progress to chronic hepatitis, or (rarely) result in acute liver failure. Chronic hepatitis may progress to scarring of the liver (cirrhosis), liver failure, and liver cancer. Hepatitis is most commonly caused by the virus ''hepatovirus A'', '' B'', '' C'', '' D'', and '' E''. Other viruses can also cause liver inflammation, including cytomegalovirus, Epstein–Barr virus, and yellow fever virus. Other common causes of hepatitis include heavy alcohol use, certain medications, toxins, other infections, autoimmune diseases, and non-alcoholic steatohepatitis (NASH). Hepa ...
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Dengue
Dengue fever is a mosquito-borne tropical disease caused by the dengue virus. Symptoms typically begin three to fourteen days after infection. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin itching and skin rash. Recovery generally takes two to seven days. In a small proportion of cases, the disease develops into a more severe dengue hemorrhagic fever, resulting in bleeding, low levels of blood platelets and blood plasma leakage, or into dengue shock syndrome, where dangerously low blood pressure occurs. Dengue is spread by several species of female mosquitoes of the ''Aedes'' genus, principally ''Aedes aegypti''. The virus has five serotypes; infection with one type usually gives lifelong immunity to that type, but only short-term immunity to the others. Subsequent infection with a different type increases the risk of severe complications. A number of tests are available to confirm the diagnosis including detecting ...
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Mayaro Virus
Mayaro may refer to: * Mayaro, California, an unincorporated community in Butte County, California, U.S. * Mayaro Bay, a bay on the east coast of the island of Trinidad * Mayaro County, a group of villages in Trinidad and Tobago ** Mayaro, Trinidad, a town in Mayaro County * Mayaro virus Mayaro may refer to: * Mayaro, California, an unincorporated community in Butte County, California, U.S. * Mayaro Bay, a bay on the east coast of the island of Trinidad * Mayaro County, a group of villages in Trinidad an ...
, a virus transmitted by the ''Haemagogus'' mosquito {{geodis ...
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Malaria
Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. Symptoms usually begin ten to fifteen days after being bitten by an infected mosquito. If not properly treated, people may have recurrences of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial resistance disappears over months to years if the person has no continuing exposure to malaria. Malaria is caused by single-celled microorganisms of the ''Plasmodium'' group. It is spread exclusively through bites of infected ''Anopheles'' mosquitoes. The mosquito bite introduces the parasites from the mosquito's saliva into a person's blood. The parasites travel to the liver where they mature and reproduce. Five species of ''Plasmodium'' can infect and be spread by h ...
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Cholera
Cholera is an infection of the small intestine by some strains of the bacterium ''Vibrio cholerae''. Symptoms may range from none, to mild, to severe. The classic symptom is large amounts of watery diarrhea that lasts a few days. Vomiting and muscle cramps may also occur. Diarrhea can be so severe that it leads within hours to severe dehydration and electrolyte imbalance. This may result in sunken eyes, cold skin, decreased skin elasticity, and wrinkling of the hands and feet. Dehydration can cause the skin to turn bluish. Symptoms start two hours to five days after exposure. Cholera is caused by a number of types of ''Vibrio cholerae'', with some types producing more severe disease than others. It is spread mostly by unsafe water and unsafe food that has been contaminated with human feces containing the bacteria. Undercooked shellfish is a common source. Humans are the only known host for the bacteria. Risk factors for the disease include poor sanitation, not enough clea ...
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Curtis Struble
James Curtis Struble (born 1953) is a former United States ambassador to Peru. Struble is a member of the Senior Foreign Service with the rank of ''Minister Counselor''. He has worked in U.S. embassies in Ecuador, Thailand, Honduras, Spain, Russia and Mexico. Biography Struble was born in Visalia, California. He received two B.A. degrees in Russian History and in Slavic Languages and Literature from the University of California, Berkeley in 1975. Between 1988 and 1989 he was a Foreign Affairs fellow at the Hoover Institution in Stanford, California. Between June 2001 and July 2002, Struble served as Deputy Assistant Secretary in the State Department's Bureau of Western Hemisphere Affairs. In this role Struble was responsible for providing broad policy oversight over U.S.-South American relations. Struble in his role in the State Department has been a vocal opponent of Fidel Castro's regime and has testified before the U.S. House of Representatives The United States House ...
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