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Nanoinformatics As A Life Cycle
Nanoinformatics is the application of informatics to nanotechnology. It is an interdisciplinary field that develops methods and software tools for understanding nanomaterials, their properties, and their interactions with biological entities, and using that information more efficiently. It differs from cheminformatics in that nanomaterials usually involve nonuniform collections of particles that have distributions of physical properties that must be specified. The nanoinformatics infrastructure includes ontologies for nanomaterials, file formats, and data repositories. Nanoinformatics has applications for improving workflows in fundamental research, manufacturing, and environmental health, allowing the use of high-throughput data-driven methods to analyze broad sets of experimental results. Nanomedicine applications include analysis of nanoparticle-based pharmaceuticals for structure–activity relationships in a similar manner to bioinformatics. Background While conventio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Informatics
Informatics is the study of computational systems, especially those for data storage and retrieval. According to ACM ''Europe and'' ''Informatics Europe'', informatics is synonymous with computer science and computing as a profession, in which the central notion is transformation of information. In other countries, the term "informatics" is used with a different meaning in the context of library science. Different meanings In some countries, depending on local interpretations, the term "informatics" is used synonymously to mean information systems, information science, information theory, information engineering, information technology, information processing, or other theoretical or practical fields. In Germany, the term ''informatics'' almost exactly corresponds to modern computer science. Accordingly, universities in continental Europe usually translate "informatics" as computer science, or sometimes information and computer science, although technical universities may t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dispersion (chemistry)
A dispersion is a system in which distributed particles of one material are dispersed in a continuous phase of another material. The two phases may be in the same or different states of matter. Dispersions are classified in a number of different ways, including how large the particles are in relation to the particles of the continuous phase, whether or not precipitation occurs, and the presence of Brownian motion. In general, dispersions of particles sufficiently large for sedimentation are called suspensions, while those of smaller particles are called colloids and solutions. Structure and properties Dispersions do not display any structure; i.e., the particles (or in case of emulsions: droplets) dispersed in the liquid or solid matrix (the "dispersion medium") are assumed to be statistically distributed. Therefore, for dispersions, usually percolation theory is assumed to appropriately describe their properties. However, percolation theory can be applied only if the sys ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ChEBI
Chemical Entities of Biological Interest, also known as ChEBI, is a chemical database and ontology of molecular entities focused on 'small' chemical compounds, that is part of the Open Biomedical Ontologies (OBO) effort at the European Bioinformatics Institute (EBI). The term "molecular entity" refers to any "constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer, etc., identifiable as a separately distinguishable entity". The molecular entities in question are either products of nature or synthetic products which have potential bioactivity. Molecules directly encoded by the genome, such as nucleic acids, proteins and peptides derived from proteins by proteolytic cleavage, are not as a rule included in ChEBI. ChEBI uses nomenclature, symbolism and terminology endorsed by the International Union of Pure and Applied Chemistry (IUPAC) and nomenclature committee of the International Union of Biochemistry and Molecular Biology ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
GitHub
GitHub, Inc. () is an Internet hosting service for software development and version control using Git. It provides the distributed version control of Git plus access control, bug tracking, software feature requests, task management, continuous integration, and wikis for every project. Headquartered in California, it has been a subsidiary of Microsoft since 2018. It is commonly used to host open source software development projects. As of June 2022, GitHub reported having over 83 million developers and more than 200 million repositories, including at least 28 million public repositories. It is the largest source code host . History GitHub.com Development of the GitHub.com platform began on October 19, 2007. The site was launched in April 2008 by Tom Preston-Werner, Chris Wanstrath, P. J. Hyett and Scott Chacon after it had been made available for a few months prior as a beta release. GitHub has an annual keynote called GitHub Universe. Organizational ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Center For Biomedical Ontology
The National Center for Biomedical Ontology (NCBO) is one of the National Centers for Biomedical Computing, and is funded by the NIH. Among the goals of the NCBO are to provide tools for discovery and access of biomedical ontologies, which are a type of controlled vocabulary designed to allow the expression of complex relationships in machine-readable form. The NCBO has facilities at Stanford University, the Mayo Clinic, the University of Victoria, and the University at Buffalo. Among the products associated with the NCBO are the Open Biomedical Ontologies The Open Biological and Biomedical Ontologies (OBO) Foundry is a group of people dedicated to build and maintain ontologies related to the life sciences. The OBO Foundry establishes a set of principles for ontology development for creating a s .... References External links NCBO Web SiteBioontology wiki National Institutes of Health Medical and health organizations based in California Medical research institutes in th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Web Ontology Language
The Web Ontology Language (OWL) is a family of knowledge representation languages for authoring ontologies. Ontologies are a formal way to describe taxonomies and classification networks, essentially defining the structure of knowledge for various domains: the nouns representing classes of objects and the verbs representing relations between the objects. Ontologies resemble class hierarchies in object-oriented programming but there are several critical differences. Class hierarchies are meant to represent structures used in source code that evolve fairly slowly (perhaps with monthly revisions) whereas ontologies are meant to represent information on the Internet and are expected to be evolving almost constantly. Similarly, ontologies are typically far more flexible as they are meant to represent information on the Internet coming from all sorts of heterogeneous data sources. Class hierarchies on the other hand tend to be fairly static and rely on far less diverse and more structu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Basic Formal Ontology
Basic Formal Ontology (BFO) is a top-level ontology developed by Barry Smith and his associates for the purposes of promoting interoperability among domain ontologies built in its terms through a process of downward population. A guide to building BFO-conformant domain ontologies was published by MIT Press in 2015. The ontology arose against the background of research in ontologies in the domain of geospatial information science by David Mark, Pierre Grenon, Achille Varzi and others, with a special role for the study of vagueness and of the ways sharp boundaries in the geospatial and other domains are created by fiat. BFO has passed through 4 major releases, documentehere The current revision was released in 2020, and this forms the basis of the standard, which was released by the Joint Committee of the International Standards Organization and International Electrotechnical Commission in 2021. The structure of BFO is based on a division of entities into two disjoint categor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nanomedicine
Nanomedicine is the medical application of nanotechnology. Nanomedicine ranges from the medical applications of nanomaterials and BioBrick, biological devices, to Nanoelectronics, nanoelectronic biosensors, and even possible future applications of molecular nanotechnology such as Molecular machine#Biological, biological machines. Current problems for nanomedicine involve understanding the issues related to Nanotoxicology, toxicity and Implications of nanotechnology, environmental impact of Nanomaterials, nanoscale materials (materials whose structure is on the scale of nanometers, i.e. billionths of a meter). Functionalities can be added to nanomaterials by interfacing them with biological molecules or structures. The size of nanomaterials is similar to that of most biological molecules and structures; therefore, nanomaterials can be useful for both in vivo and in vitro biomedical research and applications. Thus far, the integration of nanomaterials with biology has led to the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Knowledge Discovery
Knowledge extraction is the creation of Knowledge representation and reasoning, knowledge from structured (relational databases, XML) and unstructured (text (literary theory), text, documents, images) sources. The resulting knowledge needs to be in a machine-readable and machine-interpretable format and must Knowledge representation and reasoning, represent knowledge in a manner that facilitates inferencing. Although it is methodically similar to information extraction (Natural language processing, NLP) and extract, transform, load, ETL (data warehouse), the main criterion is that the extraction result goes beyond the creation of structured information or the transformation into a Database schema, relational schema. It requires either the reuse of existing Knowledge representation and reasoning, formal knowledge (reusing identifiers or ontologies) or the generation of a schema based on the source data. The RDB2RDF W3C group is currently standardizing a language for extraction of Re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Domain Of Discourse
In the formal sciences, the domain of discourse, also called the universe of discourse, universal set, or simply universe, is the set of entities over which certain variables of interest in some formal treatment may range. Overview The domain of discourse is usually identified in the preliminaries, so that there is no need in the further treatment to specify each time the range of the relevant variables. Many logicians distinguish, sometimes only tacitly, between the ''domain of a science'' and the ''universe of discourse of a formalization of the science''.José Miguel Sagüillo, Domains of sciences, universe of discourse, and omega arguments, History and philosophy of logic, vol. 20 (1999), pp. 267–280. Examples For example, in an interpretation of first-order logic, the domain of discourse is the set of individuals over which the quantifiers range. A proposition such as is ambiguous, if no domain of discourse has been identified. In one interpretation, the domain of di ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
