Mimiviridae
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Mimiviridae
''Mimiviridae'' is a family of viruses. Amoeba and other protists serve as natural hosts. The family is divided in up to 4 subfamilies., UCPMS ID: 1889607PDF/ref> Fig. 4 and §Discussion: "Considering that tupanviruses comprise a sister group to amoebal mimiviruses…" Viruses in this family belong to the nucleocytoplasmic large DNA virus clade (NCLDV), also referred to as giant viruses. ''Mimiviridae'' is the sole recognized member of order ''Imitervirales''. ''Phycodnaviridae'' and ''Pandoraviridae'' of ''Algavirales'' are sister groups of ''Mimiviridae'' in many phylogenetic analyses. History The first member of this family, Mimivirus, was discovered in 2003, and the first complete genome sequence was published in 2004. However, the mimivirus Cafeteria roenbergensis virus was isolated and partially characterized in 1995, although the host was misidentified at the time, and the virus was designated BV-PW1. Taxonomy Group: dsDNA Family ''Mimiviridae'' is currently div ...
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Nucleocytoplasmic Large DNA Virus
''Nucleocytoviricota'' is a phylum of viruses. Members of the phylum are also known as the nucleocytoplasmic large DNA viruses (NCLDV), which serves as the basis of the name of the phylum with the suffix - for virus phylum. These viruses are referred to as nucleocytoplasmic because they are often able to replicate in both the host's cell nucleus and cytoplasm. The phylum is notable for containing the giant viruses. There are nine families of NCLDVs that all share certain genomic and structural characteristics; however, it is uncertain whether the similarities of the different families of this group have a common viral ancestor. One feature of this group is a large genome and the presence of many genes involved in DNA repair, DNA replication, transcription, and translation. Typically, viruses with smaller genomes do not contain genes for these processes. Most of the viruses in this family also replicate in both the host's nucleus and cytoplasm, thus the name nucleocytoplasmic. Th ...
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Tupanvirus
Tupanvirus is a genus of viruses first described in 2018. The genus is composed of two species of virus that are in the giant virus group. Researchers discovered the first isolate in 2012 from deep water sediment samples taken at 3000m depth off the coast of Brazil. The second isolate was collected from a soda lake in Southern Nhecolândia, Brazil in 2014. They are named after Tupã (Tupan), a Guaraní thunder god, and the places they were found. These are the first viruses reported to possess genes for amino-acyl tRNA synthetases for all 20 standard amino acids. Classification The genus Tupanvirus was first described in 2018 with the discovery of the two isolates of tupanviruses found in soda lake and deep oceanic sediments samples collected in Brazil. The genus is currently unassigned but hypothesized to be a member of the family ''Mimiviridae'', along with the other amoeba-infecting viruses. Members of the family ''Mimiviridae'' includes '' Acanthamoeba polyphaga mimivirus ...
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Mimivirus
''Mimivirus'' is a genus of giant viruses, in the family ''Mimiviridae''. Amoeba serve as their natural hosts. This genus contains a single identified species named ''Acanthamoeba polyphaga mimivirus'' (APMV). It also refers to a group of phylogenetically related large viruses. In colloquial speech, APMV is more commonly referred to as just "mimivirus". Mimivirus, short for "mimicking microbe", is so called to reflect its large size and apparent Gram-staining properties. Mimivirus has a large and complex genome compared with most other viruses. Until 2013, when a larger virus ''Pandoravirus'' was described, it had the largest capsid diameter of all known viruses. History APMV was discovered accidentally in 1992 within the amoeba '' Acanthamoeba polyphaga'', after which it is named, during research into legionellosis by researchers from Marseille and Leeds. The virus was observed in a Gram stain and mistakenly thought to be a Gram-positive bacterium. As a consequence it was nam ...
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Acanthamoeba Polyphaga Mimivirus
''Mimivirus'' is a genus of giant viruses, in the family ''Mimiviridae''. Amoeba serve as their natural hosts. This genus contains a single identified species named ''Acanthamoeba polyphaga mimivirus'' (APMV). It also refers to a group of phylogenetically related large viruses. In colloquial speech, APMV is more commonly referred to as just "mimivirus". Mimivirus, short for "mimicking microbe", is so called to reflect its large size and apparent Gram-staining properties. Mimivirus has a large and complex genome compared with most other viruses. Until 2013, when a larger virus ''Pandoravirus'' was described, it had the largest capsid diameter of all known viruses. History APMV was discovered accidentally in 1992 within the amoeba '' Acanthamoeba polyphaga'', after which it is named, during research into legionellosis by researchers from Marseille and Leeds. The virus was observed in a Gram stain and mistakenly thought to be a Gram-positive bacterium. As a consequence it was nam ...
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Bodo Saltans Virus
The Bodo saltans virus is a giant virus of the ''Mimiviridae'' family that infects the protozoa ''Bodo saltans''. It has a genome of 1.39 megabases A base pair (bp) is a fundamental unit of double-stranded nucleic acids consisting of two nucleobases bound to each other by hydrogen bonds. They form the building blocks of the DNA double helix and contribute to the folded structure of both DN ..., one of the largest known viral genomes. References Mimiviridae {{Virus-stub ...
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Catovirus
''Catovirus'' (CatV) is a genus of giant double-stranded DNA-containing viruses (nucleocytoplasmic large DNA viruses). This genus was detected during the analysis of metagenome samples of bottom sediments of reservoirs at the wastewater treatment plant in Klosterneuburg, Austria. New ''Klosneuvirus'' (KNV), '' Hokovirus'' and '' Indivirus'' genera (all found in these sewage waters) were also described together with ''Catovirus'', building up a putative virus subfamily '' Klosneuvirinae'' (Klosneuviruses) with KNV as type genus. ''Catovirus'' has a large genome of 1.53 million base pairs (1176 gene families). This is the second largest genome among known Klosneuviruses after KNV (1.57 million base pairs, 1272 gene families). GC content is 26.4 % Classification of metagenome, made by analyzing 18S rRNA indicate that their hosts are relate to the simple Cercozoa. Phylogenetic tree topology of ''Mimiviridae'' is still under discussion. Some authors (CNS 2018) like to put Klosneuviru ...
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Hokovirus
''Hokovirus'' (HokV) is a genus of giant double-stranded DNA-containing viruses (NCLDV). This genus was detected during the analysis of metagenome samples of bottom sediments of reservoirs at the wastewater treatment plant in Klosterneuburg, Austria. New ''Klosneuvirus'' (KNV), ''Catovirus'' and '' Indivirus'' genera (all found in these sewage waters) were also described together with ''Hokovirus'', building up a putative virus subfamily '' Klosneuvirinae'' (Klosneuviruses) with KNV as type genus. ''Hokovirus'' has a large genome of 1.33 million base pairs (881 gene families). This is the third largest genome among known Klosneuviruses after KNV (1.57 million base pairs, 1272 gene families) and ''Catovirus''. GC content is 21.4 % Classification of metagenome, made by analyzing 18S rRNA indicate that their hosts are relate to the simple Cercozoa. Phylogenetic tree topology of ''Mimiviridae'' is still under discussion. Some authors (CNS 2018) like to put Klosneuviruses together w ...
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Indivirus
''Indivirus'' (IndV) is a genus of giant double-stranded DNA-containing viruses (NCLDV). This genus was detected during the analysis of metagenome samples of bottom sediments of reservoirs at the wastewater treatment plant in Klosterneuburg, Austria. New ''Klosneuvirus'' (KNV), ''Hokovirus'' and ''Catovirus'' genera (all found in these sewage waters) were also described together with ''Indivirus'', building up a putative virus subfamily '' Klosneuvirinae'' (Klosneuviruses) with KNV as type genus. ''Indivirus'' has a genome of 0.86 million base pairs (660 gene families). This is the smallest genome among Klosneuviruses as mentioned above. GC content is 26.6 % Classification of metagenome, made by analyzing 18S rRNA indicate that their hosts are relate to the simple Cercozoa. Phylogenetic tree topology of ''Mimiviridae'' is still under discussion. Some authors (CNS 2018) like to put Klosneuviruses together with '' Cafeteria roenbergensis virus'' (CroV) and ''Bodo saltans virus'' ...
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Klosneuvirus
''Klosneuvirus'' (KNV, also KloV) is a new type of giant virus found by the analysis of low-complexity metagenomes from a wastewater treatment plant in Klosterneuburg, Austria. It has a 1.57-Mb genome coding unusually high number of genes typically found in cellular organisms, including aminoacyl transfer RNA synthetases with specificities for 19 different amino acids, over 10 translation factors and several tRNA-modifying enzymes. ''Klosneuvirus'', ''Indivirus'', ''Catovirus'' and ''Hokovirus'', are part of a group of giant viruses denoted as Klosneuviruses or '' Klosneuvirinae'', a proposed subfamily of the ''Mimiviridae''. Species in this clade include ''Bodo saltans virus'' infecting the kinetoplastid ''Bodo saltans''. Phylogenetic tree topology of ''Mimiviridae'' is still under discussion. As Klosneuviruses are related to ''Mimivirus'', it was proposed to put them all together into a subfamily ''Megavirinae''. Other authors (CNS 2018) like to put Klosneuviruses just t ...
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Giant Viruses
A giant virus, sometimes referred to as a girus, is a very large virus, some of which are larger than typical bacteria. All known giant viruses belong to the phylum ''Nucleocytoviricota''. Description While the exact criteria as defined in the scientific literature vary, giant viruses are generally described as viruses having large, pseudo- icosahedral capsids (200 to 400 nanometers in diameter) that may be surrounded by a thick (approximately 100 nm) layer of filamentous protein fibers. The viruses have large, double-stranded DNA genomes (300 to >1000 kilobasepairs) that encode a large contingent of genes (of the order of 1000 genes). The best characterized giant viruses are the phylogenetically related mimivirus and megavirus, which belong to the family ''Mimiviridae'' (aka ''Megaviridae''), and are distinguished by their large capsid diameters. Giant viruses from the deep ocean, terrestrial sources, and human patients contain genes encoding cytochrome P450 (CYP; P450) e ...
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Mamavirus
Mamavirus is a large and complex virus in the Group I family ''Mimiviridae''. The virus is exceptionally large, and larger than many bacteria. Mamavirus and other mimiviridae belong to nucleocytoplasmic large DNA virus (NCLDVs) family. Mamavirus can be compared to the similar complex virus mimivirus; mamavirus was so named because it is similar to but larger than mimivirus. Discovery Mamavirus was first reported in September 2008. Like mimivirus, mamavirus was isolated from an amoeba in a cooling tower. The mimiviridae were not discovered until recently because of their size; when filtered the mimiviridae stay with the bacteria which led scientists to believe they were also bacteria. Mimivirus was first isolated in 1992 when scientists were looking for the cause of a pneumonia outbreak in Bradford, UK. Due to its size it was named ''Bradfordcoccus'' and put in a freezer with scientists thinking it was a bacterium. A decade later, Jean-Michel Claverie and Didier Raoult discov ...
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Cafeteria Roenbergensis Virus
''Cafeteria roenbergensis virus'' (CroV) is a giant virus that infects the marine bicosoecid flagellate ''Cafeteria roenbergensis'', a member of the microzooplankton community. History The virus was isolated from seawater samples collected from the Gulf of Mexico during 1989 to 1991, on a flagellate host that was misidentified as belonging to the genus ''Bodo''; hence the original designation of the virus as BV-PW1. The virus was shown to be about 300 nm in diameter and have a complex internal structure, as well as evidence of a putative tail-like structure Further work on the virus indicated that the host was an isolate of the genus ''Cafeteria'' and that the genome had a G+C content of ~34%. Further analysis suggested that the helicase of the virus was phylogenetically related to those found in the family '' Asfarviridae'', and that the virus shared properties with members of the Nucleocytoplasmic large DNA viruses group. CroV has one of the largest genomes of all marine ...
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