Indivirus
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''Indivirus'' (IndV) is a genus of giant double-stranded DNA-containing
virus A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1 ...
es (
NCLDV ''Nucleocytoviricota'' is a phylum of viruses. Members of the phylum are also known as the nucleocytoplasmic large DNA viruses (NCLDV), which serves as the basis of the name of the phylum with the suffix - for virus phylum. These viruses are refe ...
). This genus was detected during the analysis of metagenome samples of bottom sediments of reservoirs at the wastewater treatment plant in
Klosterneuburg Klosterneuburg (; frequently abbreviated as Kloburg by locals) is a town in Tulln District in the Austrian state of Lower Austria. It has a population of about 27,500. The Klosterneuburg Monastery, which was established in 1114 and soon after gi ...
,
Austria Austria, , bar, Östareich officially the Republic of Austria, is a country in the southern part of Central Europe, lying in the Eastern Alps. It is a federation of nine states, one of which is the capital, Vienna, the most populous ...
. New ''
Klosneuvirus ''Klosneuvirus'' (KNV, also KloV) is a new type of giant virus found by the analysis of low-complexity metagenomes from a wastewater treatment plant in Klosterneuburg, Austria. It has a 1.57-Mb genome coding unusually high number of genes typic ...
'' (KNV), ''
Hokovirus ''Hokovirus'' (HokV) is a genus of giant double-stranded DNA-containing viruses (NCLDV). This genus was detected during the analysis of metagenome samples of bottom sediments of reservoirs at the wastewater treatment plant in Klosterneuburg, Aus ...
'' and ''
Catovirus ''Catovirus'' (CatV) is a genus of giant double-stranded DNA-containing viruses (nucleocytoplasmic large DNA viruses). This genus was detected during the analysis of metagenome samples of bottom sediments of reservoirs at the wastewater treatment ...
'' genera (all found in these sewage waters) were also described together with ''Indivirus'', building up a putative virus subfamily '' Klosneuvirinae'' (Klosneuviruses) with KNV as type genus. ''Indivirus'' has a
genome In the fields of molecular biology and genetics, a genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding ge ...
of 0.86 million base pairs (660 gene families). This is the smallest genome among Klosneuviruses as mentioned above. GC content is 26.6 % Classification of metagenome, made by analyzing 18S
rRNA Ribosomal ribonucleic acid (rRNA) is a type of non-coding RNA which is the primary component of ribosomes, essential to all cells. rRNA is a ribozyme which carries out protein synthesis in ribosomes. Ribosomal RNA is transcribed from ribosoma ...
indicate that their hosts are relate to the simple Cercozoa. Phylogenetic tree topology of ''Mimiviridae'' is still under discussion. Some authors (CNS 2018) like to put Klosneuviruses together with '' Cafeteria roenbergensis virus'' (CroV) and ''
Bodo saltans virus The Bodo saltans virus is a giant virus of the ''Mimiviridae'' family that infects the protozoa ''Bodo saltans''. It has a genome of 1.39 megabases A base pair (bp) is a fundamental unit of double-stranded nucleic acids consisting of two nucleo ...
'' (BsV) into a tentative subfamily called ''Aquavirinae''.Centre national de la recherche scientifique (CNS)
List of the main “giant” viruses known as of today
Université Aix Marseille, 18. April 2018
Another proposal is to put them all together with Mimiviruses into a subfamily ''Megavirinae''.


See also

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Nucleocytoplasmic large DNA viruses ''Nucleocytoviricota'' is a phylum of viruses. Members of the phylum are also known as the nucleocytoplasmic large DNA viruses (NCLDV), which serves as the basis of the name of the phylum with the suffix - for virus phylum. These viruses are refe ...
*
Girus A giant virus, sometimes referred to as a girus, is a very large virus, some of which are larger than typical bacteria. All known giant viruses belong to the phylum '' Nucleocytoviricota''. Description While the exact criteria as defined in the ...
*
Mimiviridae ''Mimiviridae'' is a family of viruses. Amoeba and other protists serve as natural hosts. The family is divided in up to 4 subfamilies., UCPMS ID: 1889607PDF/ref> Fig. 4 and §Discussion: "Considering that tupanviruses comprise a sister gr ...


References


Further reading

* Mitch Leslie: Giant viruses found in Austrian sewage fuel debate over potential fourth domain of life. In: Science. 5. April 2017, doi:10.1126/science.aal1005. Virus genera Mimiviridae Unaccepted virus taxa