Michael S. Waterman
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Michael S. Waterman
Michael Spencer Waterman (born June 28, 1942) is a Professor of Biology, Mathematics and Computer Science at the University of Southern California (USC), where he holds an Endowed Associates Chair in Biological Sciences, Mathematics and Computer Science. He previously held positions at Los Alamos National Laboratory and Idaho State University. Education and early life Waterman grew up near Bandon, Oregon, and earned a bachelor's degree in Mathematics from Oregon State University, followed by a PhD in statistics and probability from Michigan State University in 1969. Research and career Waterman is one of the founders and current leaders in the area of computational biology. He focuses on applying mathematics, statistics, and computer science techniques to various problems in molecular biology. His work has contributed to some of the most widely used tools in the field. In particular, the Smith-Waterman algorithm (developed with Temple F. Smith) is the basis for many sequence ali ...
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Coquille, Oregon
Coquille is a city in, and the county seat of, Coos County, Oregon, United States. The population was 4,015 at the 2020 census. The primary economic base is the timber industry. The city derives its name from the Coquille Native American tribe. Geography and climate According to the United States Census Bureau, the city has a total area of , of which is land and is water. Coquille is bordered by the Coquille River which drains part of the Coastal Range into the Pacific Ocean at Bandon. According to the Köppen climate classification, Coquille has a warm-summer Mediterrean climate (Csb). The record high temperature is , set on August 15, 2020. The record low temperature is , set on December 22, 1990. There an average of 1.4 afternoons with a temperature of at least per year. Conversely, there are 37.6 mornings with a temperature of or lower. Demographics 2010 census As of the census of 2010, there were 3,866 people, 1,640 households, and 1,036 families living in ...
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De Bruijn Sequence
In combinatorial mathematics, a de Bruijn sequence of order ''n'' on a size-''k'' alphabet ''A'' is a cyclic sequence in which every possible length-''n'' string on ''A'' occurs exactly once as a substring (i.e., as a ''contiguous'' subsequence). Such a sequence is denoted by and has length , which is also the number of distinct strings of length ''n'' on ''A''. Each of these distinct strings, when taken as a substring of , must start at a different position, because substrings starting at the same position are not distinct. Therefore, must have ''at least'' symbols. And since has ''exactly'' symbols, De Bruijn sequences are optimally short with respect to the property of containing every string of length ''n'' at least once. The number of distinct de Bruijn sequences is :\dfrac. The sequences are named after the Dutch mathematician Nicolaas Govert de Bruijn, who wrote about them in 1946. As he later wrote, the existence of de Bruijn sequences for each order together ...
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Statistics
Statistics (from German language, German: ''wikt:Statistik#German, Statistik'', "description of a State (polity), state, a country") is the discipline that concerns the collection, organization, analysis, interpretation, and presentation of data. In applying statistics to a scientific, industrial, or social problem, it is conventional to begin with a statistical population or a statistical model to be studied. Populations can be diverse groups of people or objects such as "all people living in a country" or "every atom composing a crystal". Statistics deals with every aspect of data, including the planning of data collection in terms of the design of statistical survey, surveys and experimental design, experiments.Dodge, Y. (2006) ''The Oxford Dictionary of Statistical Terms'', Oxford University Press. When census data cannot be collected, statisticians collect data by developing specific experiment designs and survey sample (statistics), samples. Representative sampling as ...
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Bandon, Oregon
Bandon () is a city in Coos County, Oregon, United States, on the south side of the mouth of the Coquille River. It was named by George Bennet, an Irish peer, who settled nearby in 1873 and named the town after Bandon in Ireland, his hometown. The population was 3,066 at the 2010 census and by the 2020 census 3,321. History Before 1850, the Coquille Indians lived in the area. Then in 1851, gold was discovered at nearby Whiskey Run Beach by French Canadian trappers, though the gold rush did not have much of an impact on the area. In 1852, Henry Baldwin, from County Cork, Ireland, was shipwrecked on the Coos Bay bar and walked into this area. The first permanent European settlers came in 1853 and established the present town site. In 1856, the first conflicts with Indigenous Americans in the area arose and those were sent to the Siletz Reservation. In 1859, the boat ''Twin Sisters'' sailed into the Coquille River and opened the outlet for all inland produce and resources. ...
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PLOS Computational Biology
''PLOS Computational Biology'' is a monthly peer-reviewed open access scientific journal covering computational biology. It was established in 2005 by the Public Library of Science in association with the International Society for Computational Biology (ISCB) in the same format as the previously established ''PLOS Biology'' and ''PLOS Medicine''. The founding editor-in-chief was Philip Bourne and the current ones are Feilim Mac Gabhann and Jason Papin. Format The journal publishes both original research and review articles. All articles are open access and licensed under the Creative Commons Attribution License. Since its inception, the journal has published the ''Ten Simple Rules'' series of practical guides, which has subsequently become one of the journals most read article series. The ''Ten Simple Rules'' series then led to the ''Quick Tips'' collection, whose articles contain recommendations on computational practices and methods, such as dimensionality reduction for exam ...
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Computer Science
Computer science is the study of computation, automation, and information. Computer science spans theoretical disciplines (such as algorithms, theory of computation, information theory, and automation) to Applied science, practical disciplines (including the design and implementation of Computer architecture, hardware and Computer programming, software). Computer science is generally considered an area of research, academic research and distinct from computer programming. Algorithms and data structures are central to computer science. The theory of computation concerns abstract models of computation and general classes of computational problem, problems that can be solved using them. The fields of cryptography and computer security involve studying the means for secure communication and for preventing Vulnerability (computing), security vulnerabilities. Computer graphics (computer science), Computer graphics and computational geometry address the generation of images. Progr ...
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Mathematics
Mathematics is an area of knowledge that includes the topics of numbers, formulas and related structures, shapes and the spaces in which they are contained, and quantities and their changes. These topics are represented in modern mathematics with the major subdisciplines of number theory, algebra, geometry, and analysis, respectively. There is no general consensus among mathematicians about a common definition for their academic discipline. Most mathematical activity involves the discovery of properties of abstract objects and the use of pure reason to prove them. These objects consist of either abstractions from nature orin modern mathematicsentities that are stipulated to have certain properties, called axioms. A ''proof'' consists of a succession of applications of deductive rules to already established results. These results include previously proved theorems, axioms, andin case of abstraction from naturesome basic properties that are considered true starting points of ...
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Biology
Biology is the scientific study of life. It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. For instance, all organisms are made up of cells that process hereditary information encoded in genes, which can be transmitted to future generations. Another major theme is evolution, which explains the unity and diversity of life. Energy processing is also important to life as it allows organisms to move, grow, and reproduce. Finally, all organisms are able to regulate their own internal environments. Biologists are able to study life at multiple levels of organization, from the molecular biology of a cell to the anatomy and physiology of plants and animals, and evolution of populations.Based on definition from: Hence, there are multiple subdisciplines within biology, each defined by the nature of their research questions and the tools that they use. Like other scientists, biologists use the sc ...
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Professor
Professor (commonly abbreviated as Prof.) is an Academy, academic rank at university, universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a "person who professes". Professors are usually experts in their field and teachers of the highest rank. In most systems of List of academic ranks, academic ranks, "professor" as an unqualified title refers only to the most senior academic position, sometimes informally known as "full professor". In some countries and institutions, the word "professor" is also used in titles of lower ranks such as associate professor and assistant professor; this is particularly the case in the United States, where the unqualified word is also used colloquially to refer to associate and assistant professors as well. This usage would be considered incorrect among other academic communities. However, the otherwise unqualified title "Professor" designated with a capital let ...
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Dan David Prize
The Dan David Prize is a major international award that recognizes and supports outstanding contributions to the study of history and other disciplines that shed light on the human past. It awards nine prizes of $300,000 each year to outstanding early- and mid-career scholars and practitioners in the historical disciplines. The Prize has an annual purse of $3 million, making it the largest history award in the world, with the remaining $300,000 funding an international postdoctoral fellowship program at Tel Aviv University, where the Prize is headquartered. The Prize is endowed by the Dan David Foundation. Until 2021 the Prize awarded 3 annual prizes of $1 million for innovative and interdisciplinary research in three time dimensions: Past, Present and Future. Prize laureates donated 10 percent of their prize money to doctoral scholarships for outstanding Ph.D. students and postdoctoral scholarships in their own field from around the world. In September 2021, the Dan David Prize ...
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International Society For Computational Biology
The International Society for Computational Biology (ISCB) is a scholarly society for researchers in computational biology and bioinformatics. The society was founded in 1997 to provide a stable financial home for the Intelligent Systems for Molecular Biology (ISMB) conference and has grown to become a larger society working towards advancing understanding of living systems through computation and for communicating scientific advances worldwide. In addition to ISMB, the society also organizes a growing number of smaller, more regionally or topically focused conferences and presents a number of annual scientific achievement awards, including the Overton Prize and the ISCB Senior Scientist Awards. Overview Society membership reflects commitment toward the advancement of computational biology. The ISCB is an international non-profit organization whose members come from the global bioinformatics and computational biology communities. The ISCB serves its global membership by providing ...
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ISCB Fellow
ISCB Fellowship is an award granted to scientists that the International Society for Computational Biology (ISCB) judges to have made “outstanding contributions to the fields of computational biology and bioinformatics”. , there are 76 Fellows of the ISCB including Michael Ashburner, Alex Bateman, Bonnie Berger, Steven E. Brenner, Janet Kelso, Daphne Koller, Michael Levitt, Sarah Teichmann and Shoshana Wodak. See List of Fellows of the International Society for Computational Biology for a comprehensive listing. Fellows of the International Society for Computational Biology The first seven fellows of the ISCB were laureates of the ISCB Senior Scientist Award from 2003 to 2009: #Webb Miller Webb Colby Miller (born 1943) is a professor in the Department of Biology and the Department of Computer Science and Engineering at The Pennsylvania State University. Education Miller attended Whitman College, and received his Ph.D. in mathemati ... #David Haussler # Temple F. Smith # ...
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