Michael B. Yaffe
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Michael B. Yaffe
Michael B. Yaffe is an American scientist, professor, surgeon, and retired U.S. Army Reserve Medical Corps Colonel. He is currently the David H. Koch Professor of Biology & Biological Engineering at MIT and a trauma surgeon at the Beth Israel Deaconess Medical Center. In 2016, the United States Army awarded him the Bronze Star Medal for his services as a trauma surgeon on active duty in Afghanistan. He also treated many of the victims of the Boston Marathon bombing. Early life and education Yaffe graduated from Pikesville High School in Baltimore, MD in 1977. He received a B.S. in Materials Science & Engineering from Cornell University in 1981, and his Ph.D. and M.D. from Case Western Reserve University in 1987 and 1989, respectively. He then completed a residency at University Hospitals Cleveland Medical Center and Beth Israel Deaconess Medical Center, as well as a postdoctoral fellowship at Harvard Medical School. Research The main focus of Yaffe's research is decoding natu ...
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Professor
Professor (commonly abbreviated as Prof.) is an Academy, academic rank at university, universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a "person who professes". Professors are usually experts in their field and teachers of the highest rank. In most systems of List of academic ranks, academic ranks, "professor" as an unqualified title refers only to the most senior academic position, sometimes informally known as "full professor". In some countries and institutions, the word "professor" is also used in titles of lower ranks such as associate professor and assistant professor; this is particularly the case in the United States, where the unqualified word is also used colloquially to refer to associate and assistant professors as well. This usage would be considered incorrect among other academic communities. However, the otherwise unqualified title "Professor" designated with a capital let ...
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United States Army Medical Corps
The Medical Corps (MC) of the U.S. Army is a staff corps (non-combat specialty branch) of the U.S. Army Medical Department (AMEDD) consisting of commissioned medical officers – physicians with either an M.D. or a D.O. degree, at least one year of post-graduate clinical training, and a state medical license. The MC traces its earliest origins to the first physicians recruited by the Medical Department of the Army, created by the Second Continental Congress in 1775. The US Congress made official the designation "Medical Corps" in 1908, although the term had long been in use informally among the Medical Department's regular physicians. Currently, the MC consists of over 4,400 active duty physicians representing all the specialties and subspecialties of civilian medicine. They may be assigned to fixed military medical facilities, to deployable combat units or to military medical research and development duties. They are considered fully deployable soldiers. The Chief of the Med ...
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Combinatorial Chemistry
Combinatorial chemistry comprises chemical synthetic methods that make it possible to prepare a large number (tens to thousands or even millions) of compounds in a single process. These compound libraries can be made as mixtures, sets of individual compounds or chemical structures generated by computer software. Combinatorial chemistry can be used for the synthesis of small molecules and for peptides. Strategies that allow identification of useful components of the libraries are also part of combinatorial chemistry. The methods used in combinatorial chemistry are applied outside chemistry, too. History Combinatorial chemistry had been invented by Furka Á (Eötvös Loránd University Budapest Hungary) who described the principle of it, the combinatorial synthesis and a deconvolution procedure in a document that was notarized in 1982.Furka Á. Tanulmány, gyógyászatilag hasznosítható peptidek szisztematikus felkutatásának lehetőségéről (and Study on the possibility of sys ...
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Bioinformatics
Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combines biology, chemistry, physics, computer science, information engineering, mathematics and statistics to analyze and interpret the biological data. Bioinformatics has been used for '' in silico'' analyses of biological queries using computational and statistical techniques. Bioinformatics includes biological studies that use computer programming as part of their methodology, as well as specific analysis "pipelines" that are repeatedly used, particularly in the field of genomics. Common uses of bioinformatics include the identification of candidates genes and single nucleotide polymorphisms (SNPs). Often, such identification is made with the aim to better understand the genetic basis of disease, unique adaptations, desirable properties (e ...
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Cell Signaling
In biology, cell signaling (cell signalling in British English) or cell communication is the ability of a cell to receive, process, and transmit signals with its environment and with itself. Cell signaling is a fundamental property of all cellular life in prokaryotes and eukaryotes. Signals that originate from outside a cell (or extracellular signals) can be physical agents like mechanical pressure, voltage, temperature, light, or chemical signals (e.g., small molecules, peptides, or gas). Cell signaling can occur over short or long distances, and as a result can be classified as autocrine, juxtacrine, intracrine, paracrine, or endocrine. Signaling molecules can be synthesized from various biosynthetic pathways and released through passive or active transports, or even from cell damage. Receptors play a key role in cell signaling as they are able to detect chemical signals or physical stimuli. Receptors are generally proteins located on the cell surface or within the interio ...
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Postdoctoral Researcher
A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). The ultimate goal of a postdoctoral research position is to pursue additional research, training, or teaching in order to have better skills to pursue a career in academia, research, or any other field. Postdocs often, but not always, have a temporary academic appointment, sometimes in preparation for an academic faculty position. They continue their studies or carry out research and further increase expertise in a specialist subject, including integrating a team and acquiring novel skills and research methods. Postdoctoral research is often considered essential while advancing the scholarly mission of the host institution; it is expected to produce relevant publications in peer-reviewed academic journals or conferences. In some countries, postdoctoral research may lead to further formal qualificati ...
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University Hospitals Cleveland Medical Center
University Hospitals Cleveland Medical Center (UH Cleveland Medical Center) is a large not-for-profit academic medical complex in Cleveland, Ohio, United States. University Hospitals Cleveland Medical Center is the main affiliate hospital of Case Western Reserve University. UH Cleveland Medical Center is the main campus of the University Hospitals Health System. With 150 locations throughout the Cleveland metropolitan area, the University Hospitals Health System encompasses hospitals, outpatient centers, and primary care physicians. UH Cleveland Medical Center is home to world-class clinical and research centers, including cancer care, pediatrics, women's health, orthopedics, spine, radiology, radiation oncology, neurosurgery, neuroscience, psychiatry, cardiology, cardiovascular surgery, organ transplantation, and human genetics. Locations The main campus of the University Hospitals system is centered on the UH Cleveland Medical Center and is located in the University Circle n ...
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Maryland
Maryland ( ) is a state in the Mid-Atlantic region of the United States. It shares borders with Virginia, West Virginia, and the District of Columbia to its south and west; Pennsylvania to its north; and Delaware and the Atlantic Ocean to its east. Baltimore is the largest city in the state, and the capital is Annapolis. Among its occasional nicknames are '' Old Line State'', the ''Free State'', and the '' Chesapeake Bay State''. It is named after Henrietta Maria, the French-born queen of England, Scotland, and Ireland, who was known then in England as Mary. Before its coastline was explored by Europeans in the 16th century, Maryland was inhabited by several groups of Native Americans – mostly by Algonquian peoples and, to a lesser degree, Iroquoian and Siouan. As one of the original Thirteen Colonies of England, Maryland was founded by George Calvert, 1st Baron Baltimore, a Catholic convert"George Calvert and Cecilius Calvert, Barons Baltimore" William Hand Browne, ...
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Baltimore
Baltimore ( , locally: or ) is the most populous city in the U.S. state of Maryland, fourth most populous city in the Mid-Atlantic, and the 30th most populous city in the United States with a population of 585,708 in 2020. Baltimore was designated an independent city by the Constitution of Maryland in 1851, and today is the most populous independent city in the United States. As of 2021, the population of the Baltimore metropolitan area was estimated to be 2,838,327, making it the 20th largest metropolitan area in the country. Baltimore is located about north northeast of Washington, D.C., making it a principal city in the Washington–Baltimore combined statistical area (CSA), the third-largest CSA in the nation, with a 2021 estimated population of 9,946,526. Prior to European colonization, the Baltimore region was used as hunting grounds by the Susquehannock Native Americans, who were primarily settled further northwest than where the city was later built. Colonist ...
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Pikesville High School
Pikesville High School (PHS) is a four-year public high school in Baltimore County, Maryland, United States. It is part of the Baltimore County Public Schools consolidated school district. The school was opened in 1964 as Pikesville Senior High School with grades 9-11 and was renamed in the mid-1980s as part of a county-wide grade realignment. The classes currently span on 80 minute periods with an A and B day schedule. The school has recently received a $40 million renovation, including a math wing and science wing that replaced a single hallway of rooms and adjacent courtyard. The other courtyard was filled with more learning spaces. The cafeteria was expanded along with asbestos removal. The school is located in the community of Pikesville, just inside Baltimore County to the northwest of Baltimore City. It is located on the corner of Smith Avenue and Labyrinth Road. The school's district borders Towson High School, Dulaney High School, Owings Mills High School, New Town Hi ...
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Boston Marathon Bombing
The Boston Marathon bombing was a domestic terrorist attack that took place during the annual Boston Marathon on April 15, 2013. Two terrorists, brothers Dzhokhar Tsarnaev and Tamerlan Tsarnaev, planted two homemade pressure cooker bombs, which detonated 14 seconds and apart at 2:49p.m., near the finish line of the race, killing three people and injuring hundreds of others, including 17 who lost limbs. Three days later, on April 18, Federal Bureau of Investigation (FBI) released images of two suspects. They were later identified as the Tsarnaev brothers, who were Chechen Kyrgyzstani-Americans. Following their identification, at 10:35p.m., they killed an MIT policeman. At 11:00p.m., they kidnapped a man in his car. At 12:15a.m., on April 19, the man escaped. At 12:45a.m., they had a shootout with the police in nearby Watertown, during which two officers were severely injured (one of whom, DJ Simmonds, died a year later). Tamerlan was shot several times, and his brother Dz ...
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