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Max Bockmühl
Max Bockmühl (2 September 1882 – 5 January 1949) was a German inventor and chemist. Life Bockmühl studied chemistry and pharmacy. He worked as chemist in Germany. Together with Gustav Ehrhart working for I.G. Farbenindustrie AG at the Farbwerke Hoechst, the pair developed Methadone Methadone, sold under the brand names Dolophine and Methadose among others, is a synthetic opioid agonist used for chronic pain and also for opioid dependence. It is used to treat chronic pain, and it is also used to treat addiction to heroi ... in Germany, 1937, a drug synthesised from 1,1-diphenylbutane-2-sulfonic acid and dimethylamino-2-chloropropane, as they were looking for a synthetic opioid that could be created with readily available precursors, to solve Germany's opium shortage problem.Max Bockmuhl, Über eine neue Klasse von analgetisch wirkenden Verbindungen Ann. Chem. 561, 52 (1948) Bockmühl was married. References {{DEFAULTSORT:Bockmühl, Max 20th-century Germa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Barmen
Barmen is a former industrial metropolis of the region of Bergisches Land, Germany, which merged with four other towns in 1929 to form the city of Wuppertal. Barmen, together with the neighbouring town of Elberfeld founded the first electric suspended monorail tramway system, the Schwebebahn ''floating tram''. History Barmen was a pioneering centre for both the early industrial revolution on the European mainland, and for the socialist movement and its theory. It was the location of one of the first concentration camps in Nazi Germany, KZ Wuppertal-Barmen, later better known as Kemna concentration camp. Oberbarmen (Upper Barmen) is the eastern part of Barmen, and Unterbarmen (Lower Barmen) the western part. One of its claims to fame is the fact that Friedrich Engels, co-author of ''The Communist Manifesto'', was born in Barmen. Another of its claims is the fact that Bayer AG was founded there by Friedrich Bayer and master dyer Johann Friedrich Weskott with the express pur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Methadone 40mg
Methadone, sold under the brand names Dolophine and Methadose among others, is a synthetic opioid agonist used for chronic pain and also for opioid dependence. It is used to treat chronic pain, and it is also used to treat addiction to heroin or other opioids. Prescribed for daily use, the medicine relieves cravings and removes withdrawal symptoms. Detoxification using methadone can be accomplished in less than a month, or it may be done gradually over as long as six months. While a single dose has a rapid effect, maximum effect can take up to five days of use. The pain-relieving effects last about six hours after a single dose. After long-term use, in people with normal liver function, effects last 8 to 36 hours. Methadone is usually taken by mouth and rarely by injection into a muscle or vein. Side effects are similar to those of other opioids. These frequently include dizziness, sleepiness, vomiting, and sweating. Serious risks include opioid abuse and respiratory depress ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1882 Births
Year 188 (CLXXXVIII) was a leap year starting on Monday of the Julian calendar. At the time, it was known in the Roman Empire as the Year of the Consulship of Fuscianus and Silanus (or, less frequently, year 941 ''Ab urbe condita''). The denomination 188 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Publius Helvius Pertinax becomes pro-consul of Africa from 188 to 189. Japan * Queen Himiko (or Shingi Waō) begins her reign in Japan (until 248). Births * April 4 – Caracalla (or Antoninus), Roman emperor (d. 217) * Lu Ji (or Gongji), Chinese official and politician (d. 219) * Sun Shao, Chinese general of the Eastern Wu state (d. 241) Deaths * March 17 – Julian, pope and patriarch of Alexandria * Fa Zhen (or Gaoqing), Chinese scholar (b. AD 100) * Lucius Antistius Burrus, Roman politician (executed) * Ma Xiang, Chi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Methadone
Methadone, sold under the brand names Dolophine and Methadose among others, is a synthetic opioid agonist used for chronic pain and also for opioid dependence. It is used to treat chronic pain, and it is also used to treat addiction to heroin or other opioids. Prescribed for daily use, the medicine relieves cravings and removes withdrawal symptoms. Detoxification using methadone can be accomplished in less than a month, or it may be done gradually over as long as six months. While a single dose has a rapid effect, maximum effect can take up to five days of use. The pain-relieving effects last about six hours after a single dose. After long-term use, in people with normal liver function, effects last 8 to 36 hours. Methadone is usually taken by mouth and rarely by injection into a muscle or vein. Side effects are similar to those of other opioids. These frequently include dizziness, sleepiness, vomiting, and sweating. Serious risks include opioid abuse and respiratory depre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hoechst AG
Hoechst AG () was a German chemicals then life-sciences company that became Aventis Deutschland after its merger with France's Rhône-Poulenc S.A. in 1999. With the new company's 2004 merger with Sanofi-Synthélabo, it became a subsidiary of the resulting Sanofi-Aventis pharmaceuticals group. History The company was founded in 1863 as "Teerfarbenfabrik Meister, Lucius & Co." in Höchst, near Frankfurt and changed its name some years later to "Teerfarbenfabrik Meister Lucius & Brüning". In 1880 it became a stock company "Farbwerke vorm. Meister Lucius & Brüning AG". For the international market the name was simplified to "Farbwerke Hoechst AG". Until 1925 the Hoechst AG was independent. In 1916, the Hoechst AG was one of the co-founders of IG Farben, an advocacy group of Germany's chemicals industry to gain industrial power during and after World War I. In 1925, IG Farben turned from an advocacy group into the well-known conglomerate. World War II Various Hoechst facilit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gustav Ehrhart
Gustav Ehrhart (21 December 1894 – 11 December 1971) was a Germans, German chemist. He synthesized the first fully synthetic opioid analgesic, methadone, together with Max Bockmühl. Education and professional positions Ehrhart studied chemistry at the University of Heidelberg, with a focus on organic chemistry. His studies were interrupted by the First World War. He served as an artillery officer. After the war he resumed his studies and was awarded a doctorate degree in 1922. One of his professors was Theodor Curtius. Ehrhart received the Victor-Meyer Award for his dissertation. In 1923 he started working for Hoechst AG. Two years later he became the deputy of Max Bockmühl, the head of the pharmaceutical research laboratories of the company. In 1949, after the Second World War, Erhardt succeeded Bockmühl as the head of the entire pharmaceutical research division of Hoechst AG. In 1951 he became a deputy member of the Board, and two years later a regular member of Hoechst ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Inventor
An invention is a unique or novel device, method, composition, idea or process. An invention may be an improvement upon a machine, product, or process for increasing efficiency or lowering cost. It may also be an entirely new concept. If an idea is unique enough either as a stand alone invention or as a significant improvement over the work of others, it can be patented. A patent, if granted, gives the inventor a proprietary interest in the patent over a specific period of time, which can be licensed for financial gain. An inventor creates or discovers an invention. The word ''inventor'' comes from the Latin verb ''invenire'', ''invent-'', to find. Although inventing is closely associated with science and engineering, inventors are not necessarily engineers or scientists. Due to advances in artificial intelligence, the term "inventor" no longer exclusively applies to an occupation (see human computers). Some inventions can be patented. The system of patents was established ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bergisches Land
The Bergisches Land (, ''Berg Country'') is a low mountain range region within the state of North Rhine-Westphalia, Germany, east of Rhine river, south of the Ruhr. The landscape is shaped by woods, meadows, rivers and creeks and contains over 20 artificial lakes. Wuppertal is one of the biggest towns and seen as the region's capital, whereas the southern part nowadays has closer economic and socio-cultural ties to Cologne. Wuppertal and the neighbouring cities of Remscheid and Solingen form the Bergisches Städtedreieck. History Bergisches Land used to be territory of the County of Berg, which later became the Duchy of Berg, who gave the region its name. The Duchy was dissolved in 1815 and in 1822 the region became part of the Prussian Rhine Province. Amongst the population today, a sense of belonging to the region Bergisches Land is notable in the hilly northern part, but not so much anymore in the areas near the Cologne Bight, the Ruhr area or the city of Düsseldorf ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Germans
, native_name_lang = de , region1 = , pop1 = 72,650,269 , region2 = , pop2 = 534,000 , region3 = , pop3 = 157,000 3,322,405 , region4 = , pop4 = 21,000 3,000,000 , region5 = , pop5 = 125,000 982,226 , region6 = , pop6 = 900,000 , region7 = , pop7 = 142,000 840,000 , region8 = , pop8 = 9,000 500,000 , region9 = , pop9 = 357,000 , region10 = , pop10 = 310,000 , region11 = , pop11 = 36,000 250,000 , region12 = , pop12 = 25,000 200,000 , region13 = , pop13 = 233,000 , region14 = , pop14 = 211,000 , region15 = , pop15 = 203,000 , region16 = , pop16 = 201,000 , region17 = , pop17 = 101,000 148,00 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemist
A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a scientist trained in the study of chemistry. Chemists study the composition of matter and its properties. Chemists carefully describe the properties they study in terms of quantities, with detail on the level of molecules and their component atoms. Chemists carefully measure substance proportions, chemical reaction rates, and other chemical properties. In Commonwealth English, pharmacists are often called chemists. Chemists use their knowledge to learn the composition and properties of unfamiliar substances, as well as to reproduce and synthesize large quantities of useful naturally occurring substances and create new artificial substances and useful processes. Chemists may specialize in any number of subdisciplines of chemistry. Materials scientists and metallurgists share much of the same education and skills with chemists. The work of chemists is often related to the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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