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Gustav Ehrhart
Gustav Ehrhart (21 December 1894 – 11 December 1971) was a Germans, German chemist. He synthesized the first fully synthetic opioid analgesic, methadone, together with Max Bockmühl. Education and professional positions Ehrhart studied chemistry at the University of Heidelberg, with a focus on organic chemistry. His studies were interrupted by the First World War. He served as an artillery officer. After the war he resumed his studies and was awarded a doctorate degree in 1922. One of his professors was Theodor Curtius. Ehrhart received the Victor-Meyer Award for his dissertation. In 1923 he started working for Hoechst AG. Two years later he became the deputy of Max Bockmühl, the head of the pharmaceutical research laboratories of the company. In 1949, after the Second World War, Erhardt succeeded Bockmühl as the head of the entire pharmaceutical research division of Hoechst AG. In 1951 he became a deputy member of the Board, and two years later a regular member of Hoechst ...
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Ludwigshafen
Ludwigshafen, officially Ludwigshafen am Rhein (; meaning " Ludwig's Port upon Rhine"), is a city in the German state of Rhineland-Palatinate, on the river Rhine, opposite Mannheim. With Mannheim, Heidelberg, and the surrounding region, it forms the Rhine Neckar Area. Known primarily as an industrial city, Ludwigshafen is home to BASF, the world's largest chemical producer, and other companies. Among its cultural facilities are the Staatsphilharmonie Rheinland-Pfalz. It is the birthplace and deathplace of the former German chancellor Helmut Kohl. In 2012, Ludwigshafen was classified as a global city with ' Sufficiency' status by the Globalization and World Cities Research Network (GaWC). History Early history In antiquity, Celtic and Germanic tribes settled in the Rhine Neckar area. During the 1st century B.C. the Romans conquered the region, and a Roman auxiliary fort was constructed near the present suburb of Rheingönheim. The Middle Ages saw the foundation of some ...
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First World War
World War I (28 July 1914 11 November 1918), often abbreviated as WWI, was one of the deadliest global conflicts in history. Belligerents included much of Europe, the Russian Empire, the United States, and the Ottoman Empire, with fighting occurring throughout Europe, the Middle East, Africa, the Pacific, and parts of Asia. An estimated 9 million soldiers were killed in combat, plus another 23 million wounded, while 5 million civilians died as a result of military action, hunger, and disease. Millions more died in genocides within the Ottoman Empire and in the 1918 influenza pandemic, which was exacerbated by the movement of combatants during the war. Prior to 1914, the European great powers were divided between the Triple Entente (comprising France, Russia, and Britain) and the Triple Alliance (containing Germany, Austria-Hungary, and Italy). Tensions in the Balkans came to a head on 28 June 1914, following the assassination of Archduke Franz Ferdina ...
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IG Farben
Interessengemeinschaft Farbenindustrie AG (), commonly known as IG Farben (German for 'IG Dyestuffs'), was a German chemical and pharmaceutical conglomerate (company), conglomerate. Formed in 1925 from a merger of six chemical companies—BASF, Bayer, Hoechst AG, Hoechst, Agfa-Gevaert, Agfa, Chemische Fabrik Griesheim-Elektron, and Weiler-ter-Meer, Chemische Fabrik vorm. Weiler Ter Meer—it was seized by the Allies after World War II and divided back into its constituent companies. IG Farben was once the largest company in Europe and the largest chemical and pharmaceutical company in the world. IG Farben scientists made fundamental contributions to all areas of chemistry and the pharmaceutical industry. Otto Bayer discovered the polyaddition for the synthesis of polyurethane in 1937, and three company scientists became List of Nobel laureates, Nobel laureates: Carl Bosch and Friedrich Bergius in 1931 "for their contributions to the invention and development of chemical high pre ...
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Medizinische Monatsschrift Für Pharmazeuten
The ''Medizinische Monatsschrift für Pharmazeuten'' is a monthly peer-reviewed medical journal covering pharmacology. It has been published since 1947, originally under the title ''Medizinische Monatsschrift: Zeitschrift für allgemeine Medizin und Therapie''. Its title was changed to ''Medizinische Monatsschrift für Pharmazeuten'' in 1978. Abstracting and indexing The journal is abstracted and indexed in Chemical Abstracts, Index Medicus/MEDLINE/PubMed, and Scopus Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-l .... References External links * Pharmacology journals Publications established in 1947 {{Pharma-journal-stub ...
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Diphenylmethane
Diphenylmethane is an organic compound with the formula (C6H5)2CH2 (often abbreviated ). The compound consists of methane wherein two hydrogen atoms are replaced by two phenyl groups. It is a white solid. Diphenylmethane is a common skeleton in organic chemistry. The diphenylmethyl group is also known as ''benzhydryl''. Synthesis It is prepared by the Friedel–Crafts alkylation of benzyl chloride with benzene in the presence of a Lewis acid such as aluminium chloride: :C6H5CH2Cl + C6H6 → (C6H5)2CH2 + HCl Reactivity of the C-H bond The methylene group in diphenylmethane is mildly acidic with a p''K''a of 32.2, and so can be deprotonated with sodium amide. :(C6H5)2CH2 + NH2− → (C6H5)2CH− + NH3 The resulting carbanion can be alkylated. For example, treatment with ''n''-bromobutane produces 1,1-diphenylpentane in 92% yield. :(C6H5)2CH− + CH3CH2CH2CH2Br → (C6H5)2CHCH2CH2CH2CH3 + Br− Alkylation of various benzhydryl compounds has been demonstrated ...
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Order Of Merit Of The Federal Republic Of Germany
The Order of Merit of the Federal Republic of Germany (german: Verdienstorden der Bundesrepublik Deutschland, or , BVO) is the only federal decoration of Germany. It is awarded for special achievements in political, economic, cultural, intellectual or honorary fields. It was created by the first President of the Federal Republic of Germany, Theodor Heuss, on 7 September 1951. Colloquially, the decorations of the different classes of the Order are also known as the Federal Cross of Merit (). It has been awarded to over 200,000 individuals in total, both Germans and foreigners. Since the 1990s, the number of annual awards has declined from over 4,000, first to around 2,300–2,500 per year, and now under 2,000, with a low of 1752 in 2011. Since 2013, women have made up a steady 30–35% of recipients. Most of the German federal states (''Länder'') have each their own order of merit as well, with the exception of the Free and Hanseatic Cities of Bremen and Hamburg, which rejec ...
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Adolf Von Baeyer
Johann Friedrich Wilhelm Adolf von Baeyer (; 31 October 1835 – 20 August 1917) was a German chemist who synthesised indigo and developed a nomenclature for cyclic compounds (that was subsequently extended and adopted as part of the IUPAC organic nomenclature). He was ennobled in the Kingdom of Bavaria in 1885 and was the 1905 recipient of the Nobel Prize in Chemistry.''Adolf von Baeyer: Winner of the Nobel Prize for Chemistry 1905 '' Armin de Meijere Angewandte Chemie International Edition Volume 44, Issue 48, Pages 7836 – 7840 2005''Abstract/ref> Family and education Baeyer was born in Berlin as the son of the noted geodesist and captain of the Royal Prussian Army Johann Jacob Baeyer and his wife Eugenie Baeyer née Hitzig (1807–1843). Both his parents were Lutherans at the time of his birth and he was raised in the Lutheran religion. His mother was the daughter of Julius Eduard Hitzig and a member of the originally Jewish Itzig family, and had converted to Christianity ...
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University Of Giessen
University of Giessen, official name Justus Liebig University Giessen (german: Justus-Liebig-Universität Gießen), is a large public research university in Giessen, Hesse, Germany. It is named after its most famous faculty member, Justus von Liebig, the founder of modern agricultural chemistry and inventor of artificial fertiliser. It covers the areas of arts/humanities, business, dentistry, economics, law, medicine, science, social sciences, and veterinary medicine. Its university hospital, which has two sites, Giessen and Marburg (the latter of which is the teaching hospital of the University of Marburg), is the only private university hospital in Germany. History The University of Giessen is among the oldest institutions of higher educations in the German-speaking world. It was founded in 1607 as a Lutheran university in the city of Giessen in Hesse-Darmstadt because the all-Hessian ''Landesuniversität'' (the nearby University of Marburg (''Philipps-Universität Marburg'') ...
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University Of Stuttgart
The University of Stuttgart (german: Universität Stuttgart) is a leading research university located in Stuttgart, Germany. It was founded in 1829 and is organized into 10 faculties. It is one of the oldest technical universities in Germany with highly ranked programs in civil, mechanical, industrial and electrical engineering, among others. It is a member of TU9, an incorporated society of the largest and most notable German institutes of technology. The university is especially known for its reputation in the fields of advanced automotive engineering, efficient industrial and automated manufacturing, process engineering, aerospace engineering and activity-based costing. History From 1770 to 1794, the Karlsschule was the first university in Stuttgart. Located in Stuttgart-Hohenheim, it has since 1818 been the University of Hohenheim and is not related to the University of Stuttgart, except for some joint activities. What is now the University of Stuttgart was founded in 1 ...
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Goethe University Frankfurt
Goethe University (german: link=no, Johann Wolfgang Goethe-Universität Frankfurt am Main) is a university located in Frankfurt am Main, Germany. It was founded in 1914 as a citizens' university, which means it was founded and funded by the wealthy and active liberal citizenry of Frankfurt. The original name was Universität Frankfurt am Main. In 1932, the university's name was extended in honour of one of the most famous native sons of Frankfurt, the poet, philosopher and writer/dramatist Johann Wolfgang von Goethe. The university currently has around 45,000 students, distributed across four major campuses within the city. The university celebrated its 100th anniversary in 2014. The first female president of the university, Birgitta Wolff, was sworn into office in 2015, and was succeeded by Enrico Schleiff in 2021. 20 Nobel Prize winners have been affiliated with the university, including Max von Laue and Max Born. The university is also affiliated with 18 winners of the Gott ...
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University Of Mainz
The Johannes Gutenberg University Mainz (german: Johannes Gutenberg-Universität Mainz) is a public research university in Mainz, Rhineland Palatinate, Germany, named after the printer Johannes Gutenberg since 1946. With approximately 32,000 students (2018) in about 100 schools and clinics, it is among the largest universities in Germany. Starting on 1 January 2005 the university was reorganized into 11 faculties of study. The university is a member of the German U15, a coalition of fifteen major research-intensive and leading medical universities in Germany. The Johannes Gutenberg University is considered one of the most prestigious universities in Germany. The university is part of the IT-Cluster Rhine-Main-Neckar. The Johannes Gutenberg University Mainz, the Goethe University Frankfurt and the Technische Universität Darmstadt together form the Rhine-Main-Universities (RMU). History The first University of Mainz goes back to the Archbishop of Mainz, Prince-elector and ...
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University Of Graz
The University of Graz (german: link=no, Karl-Franzens-Universität Graz, ), located in Graz, Austria, is the largest and oldest university in Styria, as well as the second-largest and second-oldest university in Austria. History The university was founded in 1585 by Archduke Charles II of Austria. The bull of 1 January 1586, published on 15 April 1586, was approved by Pope Sixtus V. For most of its existence it was controlled by the Catholic Church, and was closed in 1782 by Emperor Joseph II in an attempt to gain state control over educational institutions. Joseph II transformed it into a ''lyceum'', where civil servants and medical personnel were trained. In 1827 it was re-instituted as a university by Emperor Francis I, thus gaining the name ''Karl-Franzens-Universität'', meaning ''Charles Francis University''. Over 30,000 students are currently enrolled at the university. Academics The university is divided into six faculties, the two largest are the Faculty ...
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