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Malabaricane
The molecule malabaricane and its derivatives, the malabaricanes, are triterpene and triterpenoid compounds found in various organisms. They are named after the rain forest tree '' Ailanthus malabarica'' (''Ailanthus triphysa''), from which they were first isolated in 1967 by scientists at the National Chemical Laboratory in Pune, India. Later, great varieties of malabaricanes were discovered in other organisms, mostly in marine sponges such as '' Rhabdastrella globostellata''. Isomalabaricanes are malabaricanes in which the three carbon ring In organic chemistry, an alicyclic compound contains one or more all-carbon rings which may be either saturated or unsaturated, but do not have aromatic character. Alicyclic compounds may have one or more aliphatic side chains attached. The ...s of the molecule are connected in '' trans−syn−trans'' conformation, as opposed to other malabaricanes, where the rings are connected in ''trans−anti−trans'' conformation. They are of p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Triterpene
Triterpenes are a class of chemical compounds composed of three terpene units with the molecular formula C30H48; they may also be thought of as consisting of six isoprene units. Animals, plants and fungi all produce triterpenes, including squalene, the precursor to all steroids. Structures Triterpenes exist in a great variety of structures. Nearly 200 different skeletons have been identified. These skeletons may be broadly divided according to the number of rings present. In general pentacyclic structures (5 rings) tend to dominate. Squalene is biosynthesized through the head-to-head condensation of two farnesyl pyrophosphate units. This coupling converts a pair of C15 components into a C30 product. Squalene serves as precursor for the formation of many triterpenoids, including bacterial hopanoids and eukaryotic sterols. Triterpenoids By definition triterpenoids are triterpenes that possess heteroatoms, usually oxygen. The terms ''triterpene'' and ''triterpenoid'' oft ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Triterpenoid
Triterpenes are a class of chemical compounds composed of three terpene units with the molecular formula C30H48; they may also be thought of as consisting of six isoprene units. Animals, plants and fungi all produce triterpenes, including squalene, the precursor to all steroids. Structures Triterpenes exist in a great variety of structures. Nearly 200 different skeletons have been identified. These skeletons may be broadly divided according to the number of rings present. In general pentacyclic structures (5 rings) tend to dominate. Squalene is biosynthesized through the head-to-head condensation of two farnesyl pyrophosphate units. This coupling converts a pair of C15 components into a C30 product. Squalene serves as precursor for the formation of many triterpenoids, including bacterial hopanoids and eukaryotic sterols. Triterpenoids By definition triterpenoids are triterpenes that possess heteroatoms, usually oxygen. The terms ''triterpene'' and ''triterpenoid'' ofte ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ailanthus Malabarica
''Ailanthus triphysa'' (also ''Ailanthus malabarica'') is a medium to tall evergreen rainforest tree in Asia and Australia. The wood may be used for matchwood and plywood. The tree is known as ''halmaddi'' in India, where its resin, also called ''halmaddi'', may be used in incense. Inappropriate extraction methods were resulting in trees dying, so by the 1990s the Indian forestry department had banned extraction. Distribution It occurs in India, including the Andaman Islands; Sri Lanka; Sri Lanka; Myanmar; South-Central and Southeast China; Thailand; Laos; Malaysia, including Peninsular Malaysia, Sarawak and Sabah; Cambodia; Vietnam; Philippines; Jawa, Kalimantan, Sulawesi and Maluku in Indonesia; and Australia. In Australia, ''Ailanthus triphysa'' occurs as two isolated populations in Western Australia (at Prince Regent River and on the offshore Coronation Island, in the Kimberley), and from Cape York in Queensland and as far south as the Susan Island Nature Reserve at Claren ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Chemical Laboratory
The National Chemical Laboratory (NCL) is an Indian government laboratory based in Pune, in western India. Popularly known as NCL, a constituent member of the CSIR India, Council of Scientific & Industrial Research (CSIR) India, it was established in 1950. Dr Ashish Lele is the Director of NCL and took charge on April 1, 2021. There are approximately 200 scientific staff working here. The interdisciplinary research center has a wide research scope and specializes in polymer science, organic chemistry, catalysis, materials chemistry, chemical engineering, biochemical sciences and process development. It houses good infrastructure for measurement science and chemical information. National Collection of Industrial Microorganisms (NCIM) is located here and is a microbial culture repository maintaining a variety of industrially important microbial culture stock. There are about 400 graduate students pursuing research towards doctoral degree; about 50 students are awarded Ph.D. de ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pune
Pune (; ; also known as Poona, (List of renamed Indian cities and states#Maharashtra, the official name from 1818 until 1978) is one of the most important industrial and educational hubs of India, with an estimated population of 7.4 million As of 2021, Pune Metropolitan Region is the largest in Maharashtra by area, with a geographical area of 7,256 sq km. It has been ranked "the most liveable city in India" several times. Pune is also considered to be the cultural and educational capital of Maharashtra. Along with the municipal corporation area of Pimpri-Chinchwad Municipal Corporation, PCMC, Pune Municipal Corporation, PMC and the three Cantonment Board, cantonment towns of Pune Camp, Camp, Khadki, and Dehu Road, Pune forms the urban core of the eponymous Pune Metropolitan Region (PMR). Situated {{convert, 560, m, 0, abbr=off Height above sea level, above sea level on the Deccan Plateau, Deccan plateau, on the right bank of the Mutha River, Mutha river,{{cite web , last=Nala ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
India
India, officially the Republic of India (Hindi: ), is a country in South Asia. It is the seventh-largest country by area, the second-most populous country, and the most populous democracy in the world. Bounded by the Indian Ocean on the south, the Arabian Sea on the southwest, and the Bay of Bengal on the southeast, it shares land borders with Pakistan to the west; China, Nepal, and Bhutan to the north; and Bangladesh and Myanmar to the east. In the Indian Ocean, India is in the vicinity of Sri Lanka and the Maldives; its Andaman and Nicobar Islands share a maritime border with Thailand, Myanmar, and Indonesia. Modern humans arrived on the Indian subcontinent from Africa no later than 55,000 years ago., "Y-Chromosome and Mt-DNA data support the colonization of South Asia by modern humans originating in Africa. ... Coalescence dates for most non-European populations average to between 73–55 ka.", "Modern human beings—''Homo sapiens''—originated in Africa. Then, int ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tetrahedron Letters
''Tetrahedron Letters'' is a weekly international journal for rapid publication of full original research papers in the field of organic chemistry. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor of 2.415. Indexing ''Tetrahedron Letters'' is indexed in: References See also *''Tetrahedron In geometry, a tetrahedron (plural: tetrahedra or tetrahedrons), also known as a triangular pyramid, is a polyhedron composed of four triangular faces, six straight edges, and four vertex corners. The tetrahedron is the simplest of all the o ...'' *'' Tetrahedron: Asymmetry'' Chemistry journals Weekly journals Publications established in 1959 Elsevier academic journals {{chem-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rhabdastrella Globostellata
''Rhabdastrella globostellata'', also known as the yellow pot sponge, is a marine sponge of the order Astrophorida. It is native to many regions of the Indian Ocean including the shores of Madagascar, the Seychelles, and Australia as well as the Malayan Peninsula and Singapore. It was first described by Henry J. Carter as ''Stelleta globostellata'' in 1883, named after the ''globostellate'' shape of its spicules (Latin ''globus'' meaning "sphere" and ''stellātus'' meaning "star-shaped"). ''R. globostellata'' has been shown to produce a wide variety of isomalabaricanes, a type of triterpene molecules with notable cytotoxic Cytotoxicity is the quality of being toxic to cells. Examples of toxic agents are an immune cell or some types of venom, e.g. from the puff adder (''Bitis arietans'') or brown recluse spider (''Loxosceles reclusa''). Cell physiology Treating cells ... activity towards certain cancer cell lines. Further reading * References Tetractinellida Animals ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journal Of Natural Products
The ''Journal of Natural Products'' is a monthly peer-reviewed scientific journal covering all aspects of research on the chemistry and/or biochemistry of naturally occurring compounds. It is co-published by the American Society of Pharmacognosy and the American Chemical Society. The editor-in-chief is Philip J. Proteau (Oregon State University). History The journal was established in 1938 as ''Lloydia'', published by the Lloyd Library and Museum, and obtained its present title in 1979. It has been the official journal of the American Society of Pharmacognosy since 1961. Originally a quarterly publication, it became a bimonthly journal in 1975, and has appeared monthly since 1992. The American Society of Pharmacognosy began to co-publish the journal with the American Chemical Society in 1996. In 2008, the journal was hijacked by a low-quality open access journal using the same title. , this counterfeit journal was still active. Abstracting and indexing The journal is abstracted a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carbon Ring
In organic chemistry, an alicyclic compound contains one or more all-carbon rings which may be either saturated or unsaturated, but do not have aromatic character. Alicyclic compounds may have one or more aliphatic side chains attached. The simplest alicyclic compounds are the monocyclic cycloalkanes: cyclopropane, cyclobutane, cyclopentane, cyclohexane, cycloheptane, cyclooctane, and so on. Bicyclic alkanes include bicycloundecane, decalin, and housane. Polycyclic alkanes include cubane, basketane, and tetrahedrane. Spiro compounds have two or more rings that are connected through only one carbon atom. The mode of ring-closing in the formation of many alicyclic compounds can be predicted by Baldwin's rules. Otto Wallach, a German chemist, received the 1910 Nobel Prize in Chemistry for his work on alicyclic compounds. Cycloalkenes Monocyclic cycloalkenes are cyclopropene, cyclobutene, cyclopentene, cyclohexene, cycloheptene, cyclooctene, and so on. Bicyclic alkenes inc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alkane Stereochemistry
In chemistry, conformational isomerism is a form of stereoisomerism in which the isomers can be interconverted just by rotations about formally single bonds (refer to figure on single bond rotation). While any two arrangements of atoms in a molecule that differ by rotation about single bonds can be referred to as different conformations, conformations that correspond to local minima on the potential energy surface are specifically called conformational isomers or conformers. Conformations that correspond to local maxima on the energy surface are the transition states between the local-minimum conformational isomers. Rotations about single bonds involve overcoming a rotational energy barrier to interconvert one conformer to another. If the energy barrier is low, there is free rotation and a sample of the compound exists as a rapidly equilibrating mixture of multiple conformers; if the energy barrier is high enough then there is restricted rotation, a molecule may exist for a rel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Culture
Cell culture or tissue culture is the process by which cells are grown under controlled conditions, generally outside of their natural environment. The term "tissue culture" was coined by American pathologist Montrose Thomas Burrows. This technique is also called micropropagation. After the cells of interest have been isolated from living tissue, they can subsequently be maintained under carefully controlled conditions the need to be kept at body temperature (37 °C) in an incubator. These conditions vary for each cell type, but generally consist of a suitable vessel with a substrate or rich medium that supplies the essential nutrients (amino acids, carbohydrates, vitamins, minerals), growth factors, hormones, and gases ( CO2, O2), and regulates the physio-chemical environment (pH buffer, osmotic pressure, temperature). Most cells require a surface or an artificial substrate to form an adherent culture as a monolayer (one single-cell thick), whereas others can be grown ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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