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Make People Better
''Make People Better'' is a 2022 documentary film about the use of genetic engineering (called CRISPR gene editing) to enhance two twins girls to be immune to HIV. Directed by Cody Sheehy of Rhumbline Media, it was originated by Samira Kiani, a biotechnologist then at Arizona State University. It focuses on the circumstances involving Chinese biologist He Jiankui who created the first genetically modified humans in 2018. Featured experts included Antonio Regalado, senior editor for biomedicine of '' MIT Technology Review'', who first discovered and revealed the secret experiment, and Benjamin Hurlbut, a bioethicist at the Arizona State University. The film was released on 13 December 2022 by Gravitas Films and Internationally by Cats & Docs. It premiered at Hot Docs Canadian International Documentary Festival, and simultaneously launched on iTunes Store and Amazon Prime Video. The title was taken from James Watson's reply as He asked him, "Do you think that that's enetically mod ...
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He Jiankui Affair
The He Jiankui affair is a scientific and bioethical controversy concerning the use of genome editing following its first use on humans by Chinese scientist He Jiankui, who edited the genomes of human embryos in 2018. He became widely known on 26 November 2018 after he announced that he had created the first human genetically edited babies. He was listed in the ''Time'''s 100 most influential people of 2019. The affair led to legal and ethical controversies, resulting in the indictment of He and two of his collaborators, Zhang Renli and Qin Jinzhou. He eventually received widespread condemnation from all over the world. He Jiankui, working at the Southern University of Science and Technology (SUSTech) in Shenzhen, China, started a project to help people with HIV-related fertility problems, specifically involving HIV-positive fathers and HIV-negative mothers. The subjects were offered standard ''in vitro'' fertilisation services and in addition, use of CRISPR gene editing (CRIS ...
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Genomics
Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dimensional structural configuration. In contrast to genetics, which refers to the study of ''individual'' genes and their roles in inheritance, genomics aims at the collective characterization and quantification of ''all'' of an organism's genes, their interrelations and influence on the organism. Genes may direct the production of proteins with the assistance of enzymes and messenger molecules. In turn, proteins make up body structures such as organs and tissues as well as control chemical reactions and carry signals between cells. Genomics also involves the sequencing and analysis of genomes through uses of high throughput DNA sequencing and bioinformatics to assemble and analyze the function and structure of entire genomes. Advances in ...
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Renminbi
The renminbi (; symbol: ¥; ISO code: CNY; abbreviation: RMB) is the official currency of the People's Republic of China and one of the world's most traded currencies, ranking as the fifth most traded currency in the world as of April 2022. The yuan ( or ) is the basic unit of the renminbi, but the word is also used to refer to the Chinese currency generally, especially in international contexts. One yuan is divided into 10 jiao (), and the jiao is further subdivided into 10 fen (). The renminbi is issued by the People's Bank of China, the monetary authority of China. Valuation Until 2005, the value of the renminbi was pegged to the US dollar. As China pursued its transition from central planning to a market economy and increased its participation in foreign trade, the renminbi was devalued to increase the competitiveness of Chinese industry. It has previously been claimed that the renminbi's official exchange rate was undervalued by as much as 37.5% against its purchas ...
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CNN News
CNN (Cable News Network) is a multinational cable news channel headquartered in Atlanta, Georgia, U.S. Founded in 1980 by American media proprietor Ted Turner and Reese Schonfeld as a 24-hour cable news channel, and presently owned by the Manhattan-based media conglomerate Warner Bros. Discovery, CNN was the first television channel to provide 24-hour news coverage and the first all-news television channel in the United States. As of September 2018, CNN had 90.1 million television households as subscribers (97.7% of households with cable). According to Nielsen, in June 2021 CNN ranked third in viewership among cable news networks, behind Fox News and MSNBC, averaging 580,000 viewers throughout the day, down 49% from a year earlier, amid sharp declines in viewers across all cable news networks. While CNN ranked 14th among all basic cable networks in 2019, then jumped to 7th during a major surge for the three largest cable news networks (completing a rankings streak of Fox N ...
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Chinese Academy Of Medical Sciences
Peking Union Medical College (), founded in 1906, is a selective public medical college based in Dongcheng, Beijing, China. It is a Chinese Ministry of Education Double First Class University Plan university. The school is tied to the Peking Union Medical College Hospital and has a joint 8-year clinical medicine science program with Tsinghua University. Peking Union Medical College students in the 8-year clinical medicine program could receive a Peking Union Medical College diploma and degree signed by both the Peking Union Medical College and Tsinghua presidents. It was merged with the Chinese Academy of Medical Sciences in 1957 and operates as one single institution with two names directly under the Ministry of Health, now the National Health Commission. It is the first medical school in China to introduce the 8-year M.D. program. History The Peking Union Medical College Hospital was founded in 1906. The American Board of Commissioners for Foreign Missions, the Board of F ...
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People's Daily
The ''People's Daily'' () is the official newspaper of the Central Committee of the Chinese Communist Party (CCP). The newspaper provides direct information on the policies and viewpoints of the CCP. In addition to its main Chinese-language edition, the ''People's Daily'' is published in multiple languages. History The paper was established on 15 June 1948 and was published in Pingshan, Hebei, until its offices were moved to Beijing in March 1949. Ever since its founding, the ''People's Daily'' has been under direct control of the CCP's top leadership. Deng Tuo and Wu Lengxi served as editor-in-chief from 1948 to 1958 and 1958–1966, respectively, but the paper was in fact controlled by Mao Zedong's personal secretary Hu Qiaomu. During the Cultural Revolution, the ''People's Daily'' was one of the few sources of information from which either foreigners or Chinese could figure out what the Chinese government was doing or planning to do. During this period, an editorial in t ...
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The New York Times
''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid digital subscribers. It also is a producer of popular podcasts such as '' The Daily''. Founded in 1851 by Henry Jarvis Raymond and George Jones, it was initially published by Raymond, Jones & Company. The ''Times'' has won 132 Pulitzer Prizes, the most of any newspaper, and has long been regarded as a national " newspaper of record". For print it is ranked 18th in the world by circulation and 3rd in the U.S. The paper is owned by the New York Times Company, which is publicly traded. It has been governed by the Sulzberger family since 1896, through a dual-class share structure after its shares became publicly traded. A. G. Sulzberger, the paper's publisher and the company's chairman, is the fifth generation of the family to head the pa ...
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Innate Resistance To HIV
A small proportion of humans show partial or apparently complete innate resistance to HIV, the virus that causes AIDS. The main mechanism is a mutation of the gene encoding CCR5, which acts as a co-receptor for HIV. It is estimated that the proportion of people with some form of resistance to HIV is under 10%. History In 1994, Stephen Crohn became the first person discovered to be completely resistant to HIV in all tests performed despite having partners infected by the virus. Crohn's resistance was a result of the absence of a receptor, which prevent the HIV from infecting CD4 present on the exterior of the white blood cells. The absence of such receptors, or rather the shortening of them to the point of being inoperable, is known as the delta 32 mutation. This mutation is linked to groups of people that have been exposed to HIV but remain uninfected such as some offspring of HIV positive mothers, health officials, and sex workers. In early 2000, researchers discovered a small ...
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CCR5-Δ32
C-C chemokine receptor type 5, also known as CCR5 or CD195, is a protein on the surface of white blood cells that is involved in the immune system as it acts as a receptor for chemokines. In humans, the ''CCR5'' gene that encodes the CCR5 protein is located on the short (p) arm at position 21 on chromosome 3. Certain populations have inherited the ''Delta 32'' mutation, resulting in the genetic deletion of a portion of the CCR5 gene. Homozygous carriers of this mutation are resistant to M-tropic strains of HIV-1 infection. Function The CCR5 protein belongs to the beta chemokine receptors family of integral membrane proteins. It is a G protein–coupled receptor which functions as a chemokine receptor in the CC chemokine group. CCR5's cognate ligands include CCL3, CCL4 (also known as MIP 1''α'' and 1''β'', respectively), and CCL3L1. CCR5 furthermore interacts with CCL5 (a chemotactic cytokine protein also known as RANTES). CCR5 is predominantly expressed on T cells ...
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University Of Hong Kong
The University of Hong Kong (HKU) (Chinese: 香港大學) is a public research university in Hong Kong. Founded in 1887 as the Hong Kong College of Medicine for Chinese, it is the oldest tertiary institution in Hong Kong. HKU was also the first university established by the British in East Asia. As of December 2022, HKU ranks 21st internationally and third in Asia by '' QS'', and 31st internationally and fourth in Asia by ''Times Higher Education''. It has been ranked as the most international university in the world as well as one of the most prestigious universities in Asia. Today, HKU has ten academic faculties with English as the main language of instruction. The University of Hong Kong was also the first team in the world to successfully isolate the coronavirus SARS-CoV, the causative agent of SARS. History Founding The origins of The University of Hong Kong can be traced back to the Hong Kong College of Medicine for Chinese founded in 1887 by Ho Kai later known a ...
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YouTube
YouTube is a global online video platform, online video sharing and social media, social media platform headquartered in San Bruno, California. It was launched on February 14, 2005, by Steve Chen, Chad Hurley, and Jawed Karim. It is owned by Google, and is the List of most visited websites, second most visited website, after Google Search. YouTube has more than 2.5 billion monthly users who collectively watch more than one billion hours of videos each day. , videos were being uploaded at a rate of more than 500 hours of content per minute. In October 2006, YouTube was bought by Google for $1.65 billion. Google's ownership of YouTube expanded the site's business model, expanding from generating revenue from advertisements alone, to offering paid content such as movies and exclusive content produced by YouTube. It also offers YouTube Premium, a paid subscription option for watching content without ads. YouTube also approved creators to participate in Google's Google AdSens ...
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Assisted Reproductive Technology
Assisted reproductive technology (ART) includes medical procedures used primarily to address infertility. This subject involves procedures such as in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), cryopreservation of gametes or embryos, and/or the use of fertility medication. When used to address infertility, ART may also be referred to as fertility treatment. ART mainly belongs to the field of reproductive endocrinology and infertility. Some forms of ART may be used with regard to fertile couples for genetic purpose (see preimplantation genetic diagnosis). ART may also be used in surrogacy arrangements, although not all surrogacy arrangements involve ART. The existence of sterility will not always require ART to be the first option to consider, as there are occasions when its cause is a mild disorder that can be solved with more conventional treatments or with behaviors based on promoting health and reproductive habits. Procedures General With ART, the pr ...
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