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Müllerian Agenesis
Müllerian agenesis, also known as Müllerian aplasia, vaginal agenesis, or Mayer-Rokitansky-Küster-Hauser syndrome (MRKH syndrome), is a congenital malformation characterized by a failure of the Müllerian ducts to develop, resulting in a missing uterus and variable degrees of vaginal hypoplasia of its upper portion. Müllerian agenesis (including absence of the uterus, cervix and/or vagina) is the cause in 15% of cases of primary amenorrhoea. Because most of the vagina does not develop from the Müllerian duct, instead developing from the urogenital sinus, along with the bladder and urethra, it is present even when the Müllerian duct is completely absent. Because ovaries do not develop from the Müllerian ducts, affected people might have normal secondary sexual characteristics but are infertile due to the lack of a functional uterus. However, parenthood is possible through use of gestational surrogates. Müllerian agenesis is hypothesized to be a result of autosomal dominant ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gynecology
Gynaecology or gynecology (see spelling differences) is the area of medicine that involves the treatment of women's diseases, especially those of the reproductive organs. It is often paired with the field of obstetrics, forming the combined area of obstetrics and gynecology (OB-GYN). The term comes from Greek and means "the science of women". Its counterpart is andrology, which deals with medical issues specific to the male reproductive system. Etymology The word "gynaecology" comes from the oblique stem (γυναικ-) of the Greek word γυνή (''gyne)'' semantically attached to "woman", and ''-logia'', with the semantic attachment "study". The word gynaecology in Kurdish means "jinekolojî", separated word as "jin-ekolojî", so the Kurdish "jin" called like "gyn" and means in Kurdish "woman". History Antiquity The Kahun Gynaecological Papyrus, dated to about 1800 BC, deals with gynaecological diseases, fertility, pregnancy, contraception, etc. The text is divided into th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Expressivity (genetics)
In genetics, expressivity is the degree to which a phenotype is expressed by individuals having a particular genotype. (Alternately, it may refer to the expression of particular gene by individuals having a certain phenotype.) Expressivity is related to the ''intensity'' of a given phenotype; it differs from penetrance, which refers to the ''proportion'' of individuals with a particular genotype that actually express the phenotype. Variable expressivity Variable expressivity refers to the degree in which a genotype is phenotypically expressed. For example, multiple people with the same disease can have the same genotype but one may express more severe symptoms, while another carrier may appear normal. This variation in expression can be affected by modifier genes, epigenetic factors or the environment. Modifier genes can alter the expression of other genes in either an additive or multiplicative way. Meaning the phenotype that is observed can be a result of two different alleles b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hernia
A hernia is the abnormal exit of tissue or an organ (anatomy), organ, such as the bowel, through the wall of the cavity in which it normally resides. Various types of hernias can occur, most commonly involving the abdomen, and specifically the groin. Groin hernias are most commonly of the inguinal hernia, inguinal type but may also be femoral hernia, femoral. Other types of hernias include Hiatal hernia, hiatus, incisional hernia, incisional, and umbilical hernias. Symptoms are present in about 66% of people with groin hernias. This may include pain or discomfort in the lower abdomen, especially with coughing, exercise, or Urination, urinating or Defecation, defecating. Often, it gets worse throughout the day and improves when lying down. A bulge may appear at the site of hernia, that becomes larger when bending down. Groin hernias occur more often on the right than left side. The main concern is Strangulation (bowel), bowel strangulation, where the blood supply to part of the bowe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Surrogacy
Surrogacy is an arrangement, often supported by a legal agreement, whereby a woman agrees to delivery/labour for another person or people, who will become the child's parent(s) after birth. People may seek a surrogacy arrangement when pregnancy is medically impossible, when pregnancy risks are dangerous for the intended mother, or when a single man or a male couple wish to have a child. In surrogacy arrangements, monetary compensation may or may not be involved. Receiving money for the arrangement is known as commercial surrogacy. The legality and cost of surrogacy varies widely between jurisdictions, sometimes resulting in problematic international or interstate surrogacy arrangements. Couples seeking a surrogacy arrangement in a country where it is banned sometimes travel to a jurisdiction that permits it. In some countries, surrogacy is legal only if money does not exchange hands. Where commercial surrogacy is legal, couples may use the help of third-party agencies to a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
In Vitro Fertilization
In vitro fertilisation (IVF) is a process of fertilisation where an egg is combined with sperm in vitro ("in glass"). The process involves monitoring and stimulating an individual's ovulatory process, removing an ovum or ova (egg or eggs) from their ovaries and letting sperm fertilise them in a culture medium in a laboratory. After the fertilised egg (zygote) undergoes embryo culture for 2–6 days, it is transferred by catheter into the uterus, with the intention of establishing a successful pregnancy. IVF is a type of assisted reproductive technology used for infertility treatment, gestational surrogacy, and, in combination with pre-implantation genetic testing, avoiding transmission of genetic conditions. A fertilised egg from a donor may implant into a surrogate's uterus, and the resulting child is genetically unrelated to the surrogate. Some countries have banned or otherwise regulate the availability of IVF treatment, giving rise to fertility tourism. Restrictions ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gynecologic Ultrasonography
Gynecologic ultrasonography or gynecologic sonography refers to the application of medical ultrasonography to the female pelvic organs (specifically the uterus, the ovaries, and the fallopian tubes) as well as the bladder, the adnexa, and the recto-uterine pouch. The procedure may lead to other medically relevant findings in the pelvis.This technique is useful to detect myomas or mullerian malformations. Routes The examination can be performed by transabdominal ultrasonography, generally with a full bladder which acts as an acoustic window to achieve better visualization of pelvis organs, or by transvaginal ultrasonography with a specifically designed vaginal transducer. Transvaginal imaging utilizes a higher frequency imaging, which gives better resolution of the ovaries, uterus and endometrium (the fallopian tubes are generally not seen unless distended), but is limited to depth of image penetration, whereas larger lesions reaching into the abdomen are better seen trans ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ovulation
Ovulation is the release of eggs from the ovaries. In women, this event occurs when the ovarian follicles rupture and release the secondary oocyte ovarian cells. After ovulation, during the luteal phase, the egg will be available to be fertilized by sperm. In addition, the uterine lining ( endometrium) is thickened to be able to receive a fertilized egg. If no conception occurs, the uterine lining as well as the egg will be shed during menstruation. Process Ovulation occurs about midway through the menstrual cycle, after the follicular phase. The days in which a person is most fertile can be calculated based on the date of the last menstrual period and the length of a typical menstrual cycle. The few days surrounding ovulation (from approximately days 10 to 18 of a 28-day cycle), constitute the most fertile phase. The time from the beginning of the last menstrual period (LMP) until ovulation is, on average, 14.6 days, but with substantial variation among females and betwe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pubarche
Pubarche refers to the first appearance of pubic hair at puberty. Pubarche is one of the physical changes of puberty and can occur independently of complete puberty. Pubarche usually results from rising levels of androgen and not estrogens in females, and androgens in males from the adrenal glands, ovaries, or testes but may also result from exposure to an anabolic steroid. When pubarche occurs prematurely (in early or mid-childhood), it is referred to as ''premature pubarche'' or precocious puberty and may warrant an evaluation. Premature adrenarche is the most common cause of premature pubarche. Early occurrences can arise due to congenital adrenal hyperplasia, androgen-producing tumors of the adrenals or gonads. When adrenarche, central puberty, and all pathologic conditions have been excluded, the term ''isolated premature pubarche'' is used to describe the unexplained development of pubic hair at an early age without other hormonal or physical changes of puberty. Average age ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thelarche
Thelarche, also known as breast budding, is the onset of secondary breast development, often representing the beginning of pubertal development. It is the stage at which male and female breasts differentiate due to variance in hormone levels; however, some males have a condition in which they develop breasts, termed gynecomastia. Thelarche typically occurs between the ages of 8 and 13 years with significant variation between individuals. However, the initial growth of breast tissue occurs during fetal development regardless of sex. Usually, females experience menarche about two years after thelarche has begun, with complete breast development from thelarche to adult breasts, taking between 2 and 4 years. Moreover, puberty is considered delayed if breast development does not start before age 13 or if a female has not had her first period (menarche) within three years of thelarche. Additionally, secondary breast development occurring before the age of 7 or 8 years could be a sign of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Puberty
Puberty is the process of physical changes through which a child's body matures into an adult body capable of sexual reproduction. It is initiated by hormonal signals from the brain to the gonads: the ovaries in a girl, the testes in a boy. In response to the signals, the gonads produce hormones that stimulate libido and the growth, function, and transformation of the brain, bones, muscle, blood, skin, hair, breasts, and sex organs. Physical growth—height and weight—accelerates in the first half of puberty and is completed when an adult body has been developed. Before puberty, the external sex organs, known as primary sexual characteristics, are sex characteristics that distinguish boys and girls. Puberty leads to sexual dimorphism through the development of the secondary sex characteristics, which further distinguish the sexes. On average, girls begin puberty at ages 10–11 and complete puberty at ages 15–17; boys generally begin puberty at ages 11–12 and complete ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carl Von Rokitansky
Baron Carl von Rokitansky (german: Carl Freiherr von Rokitansky, cs, Karel Rokytanský; 19 February 1804 – 23 July 1878) was a Bohemian physician, pathologist, humanist philosopher and liberal politician, founder of the Viennese School of Medicine of the 19th century. Founder of science-based diagnostics. Early life Carl Joseph Wenzel Prokop Rokitansky, usually known as Carl Rokitansky, was born in Hradec Králové (german: Königgrätz), Bohemia. His father Prokop Rokitansky (1871–1813) was a civil servant in Leitmeritz. His mother Theresia (1772–1827) was the daughter of Václav Lodgman Ritter von Auen, the first regional commissioner of Hradec Králové. Carl was the eldest of four children (Prokop, Marie, Theresie). Due to the early death of his father († 1812), Carl and his siblings grew up in straitened circumstances. Despite this, his mother made sure that he attended grammar school in Hradec Králové and made it possible for him to study at the Charles University ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
August Franz Josef Karl Mayer
August Franz Josef Karl Mayer (2 November 1787 in Schwäbisch Gmünd – 9 November 1865 in Bonn) was a German anatomist and physiologist. He received his education at the University of Tübingen, obtaining his doctorate in 1812. Afterwards, he worked as a prosector at the Academy of Bern, where in 1815 he was named a professor of anatomy and physiology. From 1819 to 1856 he was a professor at the University of Bonn. Among his better known students at Bonn were Johannes Peter Müller and Theodor Ludwig Wilhelm von Bischoff. His name is associated with a female reproductive disorder known today as Mayer-Rokitansky-Küster-Hauser syndrome (MRKH); named in conjunction with Carl von Rokitansky, Hermann Küster and Georges André Hauser. Selected works He was the author of around 145 published works, many of them written from the viewpoint of natural philosophy. * ''Ueber Histologie und eine neue Eintheilung der Gewebe des menschlichen Körpers'', 1819 – On histology and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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