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Multimodal Learning
Multimodal learning attempts to model the combination of different Modality (human–computer interaction), modalities of data, often arising in real-world applications. An example of multi-modal data is data that combines text (typically represented as discrete word count vectors) with imaging data consisting of pixel intensities and annotation tags. As these modalities have fundamentally different statistical properties, combining them is non-trivial, which is why specialized modelling strategies and algorithms are required. Motivation Many models and algorithms have been implemented to retrieve and classify a certain type of data, e.g. image or text (where humans who interact with machines can extract images in a form of pictures and text that could be any message etc.). However, data usually comes with different modalities (it is the degree to which a system's components may be separated or combined) which carry different information. For example, it is very common to caption ...
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Modality (human–computer Interaction)
In the context of human–computer interaction, a modality is the classification of a single independent channel of sensory input/output between a computer and a human. A system is designated unimodal if it has only one modality implemented, and multimodal if it has more than one. When multiple modalities are available for some tasks or aspects of a task, the system is said to have overlapping modalities. If multiple modalities are available for a task, the system is said to have redundant modalities. Multiple modalities can be used in combination to provide complementary methods that may be redundant but convey information more effectively. Modalities can be generally defined in two forms: human-computer and computer-human modalities. Computer–Human modalities Computers utilize a wide range of technologies to communicate and send information to humans: * Common modalities ** Vision – computer graphics typically through a screen ** Audition – various audio outputs ** Tacti ...
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Latent Dirichlet Allocation
In natural language processing, Latent Dirichlet Allocation (LDA) is a generative statistical model that explains a set of observations through unobserved groups, and each group explains why some parts of the data are similar. The LDA is an example of a topic model. In this, observations (e.g., words) are collected into documents, and each word's presence is attributable to one of the document's topics. Each document will contain a small number of topics. History In the context of population genetics, LDA was proposed by J. K. Pritchard, M. Stephens and P. Donnelly in 2000. LDA was applied in machine learning by David Blei, Andrew Ng and Michael I. Jordan in 2003. Overview Evolutionary biology and bio-medicine In evolutionary biology and bio-medicine, the model is used to detect the presence of structured genetic variation in a group of individuals. The model assumes that alleles carried by individuals under study have origin in various extant or past populations. The ...
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Markov Chain Monte Carlo
In statistics, Markov chain Monte Carlo (MCMC) methods comprise a class of algorithms for sampling from a probability distribution. By constructing a Markov chain that has the desired distribution as its equilibrium distribution, one can obtain a sample of the desired distribution by recording states from the chain. The more steps that are included, the more closely the distribution of the sample matches the actual desired distribution. Various algorithms exist for constructing chains, including the Metropolis–Hastings algorithm. Application domains MCMC methods are primarily used for calculating numerical approximations of multi-dimensional integrals, for example in Bayesian statistics, computational physics, computational biology and computational linguistics. In Bayesian statistics, the recent development of MCMC methods has made it possible to compute large hierarchical models that require integrations over hundreds to thousands of unknown parameters. In rare even ...
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Markov Random Field
In the domain of physics and probability, a Markov random field (MRF), Markov network or undirected graphical model is a set of random variables having a Markov property described by an undirected graph. In other words, a random field is said to be a Markov random field if it satisfies Markov properties. The concept originates from the Sherrington–Kirkpatrick model. A Markov network or MRF is similar to a Bayesian network in its representation of dependencies; the differences being that Bayesian networks are directed and acyclic, whereas Markov networks are undirected and may be cyclic. Thus, a Markov network can represent certain dependencies that a Bayesian network cannot (such as cyclic dependencies ); on the other hand, it can't represent certain dependencies that a Bayesian network can (such as induced dependencies ). The underlying graph of a Markov random field may be finite or infinite. When the joint probability density of the random variables is strictly positive, it ...
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Hopfield Network
A Hopfield network (or Ising model of a neural network or Ising–Lenz–Little model) is a form of recurrent artificial neural network and a type of spin glass system popularised by John Hopfield in 1982 as described earlier by Little in 1974 based on Ernst Ising's work with Wilhelm Lenz on the Ising model. Hopfield networks serve as content-addressable ("associative") memory systems with binary threshold nodes, or with continuous variables. Hopfield networks also provide a model for understanding human memory. Origins The Ising model of a neural network as a memory model was first proposed by William A. Little in 1974, which was acknowledged by Hopfield in his 1982 paper. Networks with continuous dynamics were developed by Hopfield in his 1984 paper. A major advance in memory storage capacity was developed by Krotov and Hopfield in 2016 through a change in network dynamics and energy function. This idea was further extended by Demircigil and collaborators in 2017. The contin ...
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Brigham And Women's Hospital
Brigham and Women's Hospital (BWH) is the second largest teaching hospital of Harvard Medical School and the largest hospital in the Longwood Medical and Academic Area, Longwood Medical Area in Boston, Massachusetts. Along with Massachusetts General Hospital, it is one of the two founding members of Mass General Brigham, the largest healthcare provider in Massachusetts. Sunil Eappen serves as the hospital's current president. Brigham and Women's Hospital conducts the second largest (behind MGH) hospital-based research program in the world, with an annual research budget of more than $630 million. Pioneering achievements at BWH have included the world's first successful heart valve operation and the world's first solid organ transplant. In the 2020 ''U.S. News & World Report'' hospital rankings, BWH was ranked second in Massachusetts (behind MGH) and twelfth nationally. History Brigham and Women's Hospital was established with the 1980 merger of three Harvard-affiliated hospita ...
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Data Integration
Data integration involves combining data residing in different sources and providing users with a unified view of them. This process becomes significant in a variety of situations, which include both commercial (such as when two similar companies need to merge their databases) and scientific (combining research results from different bioinformatics repositories, for example) domains. Data integration appears with increasing frequency as the volume (that is, big data) and the need to share existing data explodes. It has become the focus of extensive theoretical work, and numerous open problems remain unsolved. Data integration encourages collaboration between internal as well as external users. The data being integrated must be received from a heterogeneous database system and transformed to a single coherent data store that provides synchronous data across a network of files for clients. A common use of data integration is in data mining when analyzing and extracting informati ...
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Cancer Screening
Cancer screening aims to detect cancer before symptoms appear. This may involve blood tests, urine tests, DNA tests, other tests, or medical imaging. The benefits of screening in terms of cancer prevention, early detection and subsequent treatment must be weighed against any harms. Universal screening, also known as mass screening or population screening, involves screening everyone, usually within a specific age group. Selective screening identifies people who are known to be at higher risk of developing cancer, such as people with a family history of cancer. Screening can lead to false positive results and subsequent invasive procedures. Screening can also lead to false negative results, where an existing cancer is missed. Controversy arises when it is not clear if the benefits of screening outweigh the risks of the screening procedure itself, and any follow-up diagnostic tests and treatments. Screening tests must be effective, safe, well tolerated with acceptably low rates o ...
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DALL-E
DALL-E (stylized as DALL·E) and DALL-E 2 are deep learning models developed by OpenAI to generate digital images from natural language descriptions, called "prompts". DALL-E was revealed by OpenAI in a blog post in January 2021, and uses a version of GPT-3 modified to generate images. In April 2022, OpenAI announced DALL-E 2, a successor designed to generate more realistic images at higher resolutions that "can combine concepts, attributes, and styles". OpenAI has not released source code for either model. On 20 July 2022, DALL-E 2 entered into a beta phase with invitations sent to 1 million waitlisted individuals; users can generate a certain number of images for free every month and may purchase more. Access had previously been restricted to pre-selected users for a research preview due to concerns about ethics and safety. On 28 September 2022, DALL-E 2 was opened to anyone and the waitlist requirement was removed. In early November 2022, OpenAI released DALL-E 2 as an API, ...
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OpenAI
OpenAI is an artificial intelligence (AI) research laboratory consisting of the for-profit corporation OpenAI LP and its parent company, the non-profit OpenAI Inc. The company conducts research in the field of AI with the stated goal of promoting and developing friendly AI in a way that benefits humanity as a whole. The organization was founded in San Francisco in late 2015 by Sam Altman, Elon Musk, and others, who collectively pledged US$1 billion. Musk resigned from the board in February 2018 but remained a donor. In 2019, OpenAI LP received a 1 billion investment from Microsoft. OpenAI is headquartered at the Pioneer Building in Mission District, San Francisco. History In December 2015, Sam Altman, Elon Musk, Greg Brockman, Reid Hoffman, Jessica Livingston, Peter Thiel, Amazon Web Services (AWS), Infosys, and YC Research announced the formation of OpenAI and pledged over 1 billion to the venture. The organization stated it would "freely collaborate" wi ...
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Deep Belief Network
In machine learning, a deep belief network (DBN) is a generative graphical model, or alternatively a class of deep neural network, composed of multiple layers of latent variables ("hidden units"), with connections between the layers but not between units within each layer. When trained on a set of examples without supervision, a DBN can learn to probabilistically reconstruct its inputs. The layers then act as feature detectors. After this learning step, a DBN can be further trained with supervision to perform classification. DBNs can be viewed as a composition of simple, unsupervised networks such as restricted Boltzmann machines (RBMs) or autoencoders, where each sub-network's hidden layer serves as the visible layer for the next. An RBM is an undirected, generative energy-based model with a "visible" input layer and a hidden layer and connections between but not within layers. This composition leads to a fast, layer-by-layer unsupervised training procedure, where contrastiv ...
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Support Vector Machine
In machine learning, support vector machines (SVMs, also support vector networks) are supervised learning models with associated learning algorithms that analyze data for classification and regression analysis. Developed at AT&T Bell Laboratories by Vladimir Vapnik with colleagues (Boser et al., 1992, Guyon et al., 1993, Cortes and Vapnik, 1995, Vapnik et al., 1997) SVMs are one of the most robust prediction methods, being based on statistical learning frameworks or VC theory proposed by Vapnik (1982, 1995) and Chervonenkis (1974). Given a set of training examples, each marked as belonging to one of two categories, an SVM training algorithm builds a model that assigns new examples to one category or the other, making it a non- probabilistic binary linear classifier (although methods such as Platt scaling exist to use SVM in a probabilistic classification setting). SVM maps training examples to points in space so as to maximise the width of the gap between the two categories. New ...
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