Mucrolysin
Mucrolysin (, ''Trimeresurus metalloendopeptidase A'', ''mucrotoxin A'') is an enzyme. This enzyme catalyses the following chemical reaction : Cleavage of Ser9-His, His10-Leu, Ala14-Leu, Leu15-Tyr and Tyr16-Leu bonds in insulin B chain This endopeptidase from the venom of Taiwan habu snake (''Protobothrops mucrosquamatus ''Protobothrops mucrosquamatus'' is a venomous pit viper species endemic to Asia. Common names include: brown-spotted pit viper,Gumprecht A, Tillack F, Orlov NL, Captain A, Ryabov S. 2004. ''Asian Pitvipers''. Geitje Books. Berlin. 1st Edition ...''). References External links * {{Portal bar, Biology, border=no EC 3.4.24 ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. Almost all metabolic processes in the cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts are catalytic RNA molecules, called ribozymes. Enzymes' specificity comes from their unique three-dimensional structures. Like all catalysts, enzymes increase the reaction ra ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Catalysis
Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recycles quickly, very small amounts of catalyst often suffice; mixing, surface area, and temperature are important factors in reaction rate. Catalysts generally react with one or more reactants to form intermediates that subsequently give the final reaction product, in the process of regenerating the catalyst. Catalysis may be classified as either homogeneous, whose components are dispersed in the same phase (usually gaseous or liquid) as the reactant, or heterogeneous, whose components are not in the same phase. Enzymes and other biocatalysts are often considered as a third category. Catalysis is ubiquitous in chemical industry of all kinds. Estimates are that 90% of all commercially produced chemical products involve catalysts at some s ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Chemical Reaction
A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the positions of electrons in the forming and breaking of chemical bonds between atoms, with no change to the Atomic nucleus, nuclei (no change to the elements present), and can often be described by a chemical equation. Nuclear chemistry is a sub-discipline of chemistry that involves the chemical reactions of unstable and radioactive Chemical element, elements where both electronic and nuclear changes can occur. The substance (or substances) initially involved in a chemical reaction are called reagent, reactants or reagents. Chemical reactions are usually characterized by a chemical change, and they yield one or more Product (chemistry), products, which usually have properties different from the reactants. Reactions often consist of a sequence o ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Insulin
Insulin (, from Latin ''insula'', 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the ''INS'' gene. It is considered to be the main anabolic hormone of the body. It regulates the metabolism of carbohydrates, fats and protein by promoting the absorption of glucose from the blood into liver, fat and skeletal muscle cells. In these tissues the absorbed glucose is converted into either glycogen via glycogenesis or fats (triglycerides) via lipogenesis, or, in the case of the liver, into both. Glucose production and secretion by the liver is strongly inhibited by high concentrations of insulin in the blood. Circulating insulin also affects the synthesis of proteins in a wide variety of tissues. It is therefore an anabolic hormone, promoting the conversion of small molecules in the blood into large molecules inside the cells. Low insulin levels in the blood have the opposite effect by promoting widespread catabolism, especially o ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Endopeptidase
Endopeptidase or endoproteinase are proteolytic peptidases that break peptide bonds of nonterminal amino acids (i.e. within the molecule), in contrast to exopeptidases, which break peptide bonds from end-pieces of terminal amino acids. For this reason, endopeptidases cannot break down peptides into monomers, while exopeptidases can break down proteins into monomers. A particular case of endopeptidase is the oligopeptidase, whose substrates are oligopeptides instead of proteins. They are usually very specific for certain amino acids. Examples of endopeptidases include: * Trypsin - cuts after Arg or Lys, unless followed by Pro. Very strict. Works best at pH 8. * Chymotrypsin - cuts after Phe, Trp, or Tyr, unless followed by Pro. Cuts more slowly after His, Met or Leu. Works best at pH 8. * Elastase - cuts after Ala, Gly, Ser, or Val, unless followed by Pro. * Thermolysin - cuts ''before'' Ile, Met, Phe, Trp, Tyr, or Val, unless ''preceded'' by Pro. Sometimes cuts after Ala, Asp ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Habu Snake
is a Ryukyuan and Japanese name referring to certain venomous snakes: * The following species are found in the Ryukyu Islands of Japan: ** ''Protobothrops elegans'', a.k.a. the Sakishima habu, found in the southern Ryukyu Islands ** ''Protobothrops flavoviridis'', a.k.a. the Okinawan habu, found in the southern Ryukyu Islands ** ''Protobothrops tokarensis'', a.k.a. the Tokara habu, found in the Tokara Islands ** ''Ovophis okinavensis'', a.k.a. the Hime habu * Habu is a name also used for several other species: ** ''Trimeresurus gracilis'', a.k.a. the Kikushi habu, found in Taiwan. ** ''Protobothrops mucrosquamatus'', a.k.a. the Taiwan habu or Chinese habu, found in Southeast Asia. ** ''Ovophis monticola'', a.k.a. the Arisan habu, found in Southeast Asia. * ''Habu'' is a nickname given to the Lockheed SR-71 Blackbird The Lockheed SR-71 "Blackbird" is a long-range, high-altitude, Mach 3+ strategic reconnaissance aircraft developed and manufactured by the American aeros ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Protobothrops Mucrosquamatus
''Protobothrops mucrosquamatus'' is a venomous pit viper species endemic to Asia. Common names include: brown-spotted pit viper,Gumprecht A, Tillack F, Orlov NL, Captain A, Ryabov S. 2004. ''Asian Pitvipers''. Geitje Books. Berlin. 1st Edition. 368 pp. . Taiwanese habu and pointed-scaled pit viper.U.S. Navy. 1991. ''Poisonous Snakes of the World''. US Govt. New York: Dover Publications Inc. 203 pp. . No subspecies are currently recognized. The species was first described by Theodore Cantor in 1839. Description Males grow to a maximum total length of with a tail length of . Females grow to a maximum total length of with a tail length of . The hemipenes are spinose. Scalation: dorsal scales in 25 longitudinal rows at midbody; scales on upper surface of head, small, each scale keeled posteriorly; internasals 5–10 times size of adjacent scales, separated by 3–4 scales; supraoculars, long, narrow, undivided, 14–16 small interoculars in line between them; 2 scales ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |