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Mucrolysin (, ''Trimeresurus metalloendopeptidase A'', ''mucrotoxin A'') is an
enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
. This enzyme catalyses the following
chemical reaction A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...
: Cleavage of Ser9-His, His10-Leu, Ala14-Leu, Leu15-Tyr and Tyr16-Leu bonds in
insulin Insulin (, from Latin ''insula'', 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the ''INS'' gene. It is considered to be the main anabolic hormone of the body. It regulates the metabolism o ...
B chain This
endopeptidase Endopeptidase or endoproteinase are proteolytic peptidases that break peptide bonds of nonterminal amino acids (i.e. within the molecule), in contrast to exopeptidases, which break peptide bonds from end-pieces of terminal amino acids. For this re ...
from the venom of Taiwan habu snake (''
Protobothrops mucrosquamatus ''Protobothrops mucrosquamatus'' is a venomous pit viper species endemic to Asia. Common names include: brown-spotted pit viper,Gumprecht A, Tillack F, Orlov NL, Captain A, Ryabov S. 2004. ''Asian Pitvipers''. Geitje Books. Berlin. 1st Edition ...
'').


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* {{Portal bar, Biology, border=no EC 3.4.24