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Morbillivirus Infections
''Morbillivirus'' is a genus of viruses in the order '' Mononegavirales'', in the family '' Paramyxoviridae''. Humans, dogs, cats, cattle, seals, and cetaceans serve as natural hosts. This genus includes seven species. Diseases in humans associated with viruses classified in this genus include measles Measles is a highly contagious infectious disease caused by measles virus. Symptoms usually develop 10–12 days after exposure to an infected person and last 7–10 days. Initial symptoms typically include fever, often greater than , cough, ...; in animals, they include acute febrile respiratory tract infection. In 2013, a wave of increased death among the Common bottlenose dolphin population was attributed to morbillivirus. Genus Structure Morbillivirions are enveloped, with spherical geometries. Their diameter is around 150 nm. Genomes are linear, around 15-16 kb in length. The genome codes for eight proteins. Life cycle Viral replication is cytoplasmic. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Measles Morbillivirus
''Measles morbillivirus'' (MeV), also called measles virus (MV), is a single-stranded, negative-sense, enveloped, non-segmented RNA virus of the genus ''Morbillivirus'' within the family ''Paramyxoviridae''. It is the cause of measles. Humans are the natural hosts of the virus; no animal reservoirs are known to exist. Disease The virus causes measles, a highly contagious disease transmitted by respiratory aerosols that triggers a temporary but severe immunosuppression. Symptoms include fever, cough, runny nose, inflamed eyes and a generalized, maculopapular, erythematous rash and a pathognomic Koplik spot seen on buccal mucosa opposite to lower 1 st and 2 nd molars . The virus is spread by coughing and sneezing via close personal contact or direct contact with secretions. Replication cycle Entry The measles virus has two envelope glycoproteins on the viral surface – hemagglutinin (H) and membrane fusion protein (F). These proteins are responsible for host cell bi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Canine Distemper Virus
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Canine may refer to: Zoology and anatomy * a dog-like Canid animal in the subfamily Caninae ** ''Canis'', a genus including dogs, wolves, coyotes, and jackals ** Dog, the domestic dog * Canine tooth, in mammalian oral anatomy People with the surname * Henry Canine (), American football coach * Ralph Canine (1895–1969), founding director of the United States National Security Agency Other uses * Canine, a fictional dog in the ''Glenn Martin, DDS'' animated television series * Canine Hills, Antarctic landform in the Bowers Mountains, Victoria Land See also * K9 (other) * Kanine (other) * Canina (other) * Cani (other) * List of canids Canidae is a family of mammals in the order Carnivora, which includes domestic dogs, wolves, coyotes, foxes, jackals, dingoes, and many other extant and extinct dog-like mammals. A member of this family is called a canid; all extant spec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cetacea
Cetacea (; , ) is an infraorder of aquatic mammals that includes whales, dolphins, and porpoises. Key characteristics are their fully aquatic lifestyle, streamlined body shape, often large size and exclusively carnivorous diet. They propel themselves through the water with powerful up-and-down movement of their tail which ends in a paddle-like fluke, using their flipper-shaped forelimbs to maneuver. While the majority of cetaceans live in marine environments, a small number exclusively reside in brackish water or fresh water. Having a cosmopolitan distribution, they can be found in some rivers and all of Earth's oceans, and many species inhabit vast ranges where they migrate with the changing of the seasons. Cetaceans are famous for their high intelligence and complex social behaviour as well as for the enormous size of some of the group's members, such as the blue whale which reaches a maximum confirmed length of 29.9 meters (98 feet) and a weight of 173 tonnes (190 short to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polymerase Stuttering
Polymerase stuttering is the process by which a polymerase transcribes a nucleotide several times without progressing further on the mRNA chain. It is often used in addition of poly A tails or capping mRNA chains by less complex organisms such as viruses. Process A polymerase may undergo stuttering as a probability controlled event, hence it is not explicitly controlled by any mechanisms in the translation process. Generally, it is a result of many short repeated frameshifts on a slippery sequence of nucleotides on the mRNA strand. However, the frameshift is restricted to one (in some cases two) nucleotides with a pseudoknot or choke points on both sides of the sequence. Examples A polymerase that exhibits this behavior is RNA-dependent RNA polymerase, present in many RNA viruses. Reverse transcriptase A reverse transcriptase (RT) is an enzyme used to generate complementary DNA (cDNA) from an RNA template, a process termed reverse transcription. Reverse transcr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Morbillivirus Genomes
''Morbillivirus'' is a genus of viruses in the order '' Mononegavirales'', in the family '' Paramyxoviridae''. Humans, dogs, cats, cattle, seals, and cetaceans serve as natural hosts. This genus includes seven species. Diseases in humans associated with viruses classified in this genus include measles; in animals, they include acute febrile respiratory tract infection. In 2013, a wave of increased death among the Common bottlenose dolphin population was attributed to morbillivirus. Genus Structure Morbillivirions are enveloped, with spherical geometries. Their diameter is around 150 nm. Genomes are linear, around 15-16 kb in length. The genome codes for eight proteins. Life cycle Viral replication is cytoplasmic. Entry into the host cell is achieved by virus attaching to host cell. Replication follows the negative-stranded RNA virus replication model. Negative-stranded RNA virus transcription, using polymerase stuttering Polymerase stuttering is the process by w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Viral Envelope
A viral envelope is the outermost layer of many types of viruses. It protects the genetic material in their life cycle when traveling between host cells. Not all viruses have envelopes. Numerous human pathogenic viruses in circulation are encased in lipid bilayers, and they infect their target cells by causing the viral envelope and cell membrane to fuse. Although there are effective vaccines against some of these viruses, there is no preventative or curative medicine for the majority of them. In most cases, the known vaccines operate by inducing antibodies that prevent the pathogen from entering cells. This happens in the case of enveloped viruses when the antibodies bind to the viral envelope proteins. The membrane fusion event that triggers viral entrance is caused by the viral fusion protein. Many enveloped viruses only have one protein visible on the surface of the particle, which is required for both mediating adhesion to the cell surface and for the subsequent membrane fusi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Morbillivirus Virion2
''Morbillivirus'' is a genus of viruses in the order '' Mononegavirales'', in the family '' Paramyxoviridae''. Humans, dogs, cats, cattle, seals, and cetaceans serve as natural hosts. This genus includes seven species. Diseases in humans associated with viruses classified in this genus include measles; in animals, they include acute febrile respiratory tract infection. In 2013, a wave of increased death among the Common bottlenose dolphin population was attributed to morbillivirus. Genus Structure Morbillivirions are enveloped, with spherical geometries. Their diameter is around 150 nm. Genomes are linear, around 15-16 kb in length. The genome codes for eight proteins. Life cycle Viral replication is cytoplasmic. Entry into the host cell is achieved by virus attaching to host cell. Replication follows the negative-stranded RNA virus replication model. Negative-stranded RNA virus transcription, using polymerase stuttering Polymerase stuttering is the process by w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rinderpest Virus
Rinderpest (also cattle plague or steppe murrain) was an infectious viral disease of cattle, domestic buffalo, and many other species of even-toed ungulates, including gaurs, buffaloes, large antelope, deer, giraffes, wildebeests, and warthogs. The disease was characterized by fever, oral erosions, diarrhea, lymphoid necrosis, and high mortality. Death rates during outbreaks were usually extremely high, approaching 100% in immunologically naïve populations. Rinderpest was mainly transmitted by direct contact and by drinking contaminated water, although it could also be transmitted by air. After a global eradication campaign starting in the mid-20th century, the last confirmed case of rinderpest was diagnosed in 2001. On 14 October 2010, the United Nations Food and Agriculture Organization (FAO) announced that field activities in the decades-long, worldwide campaign to eradicate the disease were ending, paving the way for a formal declaration in June 2011 of the glo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phocine Distemper Virus
''Phocine morbillivirus'', formerly ''phocine distemper virus'' (PDV), is a paramyxovirus of the genus ''Morbillivirus'' that is pathogenic for pinniped species, particularly seals. Clinical signs include laboured breathing, fever and nervous symptoms. PDV was first identified in 1988 as the cause of death of 18,000 harbor seals (''Phoca vitulina'') and 300 grey seals (''Halichoerus grypus'') along the northern European coast. In 2002, an epizootic of PDV along the North Sea coast resulted in the deaths of 21,700 seals, estimated to be 51% of the population. Antibodies to PDV have been found in a number of carnivorous mammal species in the Western North Atlantic, including polar bears, and the Atlantic walrus. The suddenness of the emergence of PDV and related viruses in aquatic mammals has implicated environmental changes as the cause. Pollutants have been posited as contributors by interfering with the ability of animals to mount a defense against infection. Alternatively ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ovine Rinderpest
Ovine rinderpest, also commonly known as ''peste des petits ruminants'' (PPR), is a contagious disease primarily affecting goats and sheep; however, camels and wild small ruminants can also be affected. PPR is currently present in North, Central, West and East Africa, the Middle East, and South Asia. It is caused by ''small ruminants morbillivirus'' in the genus '' Morbillivirus,'' and is closely related to, among others,'' rinderpest morbillivirus, measles morbillivirus'', and ''canine morbillivirus'' (previously known as canine distemper virus). The disease is highly contagious, and can have an 80–100% mortality rate in acute cases in an epizootic setting. The virus does not infect humans. The disease was first described in 1942 in Côte d'Ivoire, and has since been detected in more than 70 countries in the world. In 2017, the disease was reported to be affecting saiga in Mongolia, causing near-catastrophic herd depletion for the endangered species. In 2018, it ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Measles Virus
''Measles morbillivirus'' (MeV), also called measles virus (MV), is a single-stranded, negative-sense, enveloped, non-segmented RNA virus of the genus ''Morbillivirus'' within the family ''Paramyxoviridae''. It is the cause of measles. Humans are the natural hosts of the virus; no animal reservoirs are known to exist. Disease The virus causes measles, a highly contagious disease transmitted by respiratory aerosols that triggers a temporary but severe immunosuppression. Symptoms include fever, cough, runny nose, inflamed eyes and a generalized, maculopapular, erythematous rash and a pathognomic Koplik spot seen on buccal mucosa opposite to lower 1 st and 2 nd molars . The virus is spread by coughing and sneezing via close personal contact or direct contact with secretions. Replication cycle Entry The measles virus has two envelope glycoproteins on the viral surface – hemagglutinin (H) and membrane fusion protein (F). These proteins are responsible for host cell ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Common Bottlenose Dolphin
The common bottlenose dolphin or Atlantic bottlenose dolphin (''Tursiops truncatus'') is a wide-ranging marine mammal of the family Delphinidae. The common bottlenose dolphin is a very familiar dolphin due to the wide exposure it gets in captivity in marine parks and dolphinariums, and in movies and television programs.Leatherwood, S., & Reeves, R. (1990). ''The Bottlenose Dolphin''. San Diego: Academic Press, Inc., It is the largest species of the beaked dolphins. It inhabits temperate and tropical oceans throughout the world, and is absent only from polar waters.Klinowska, M. (1991). ''Dolphins, Porpoises and Whales of the World: The IUCN Red Data Book''. Gland, Switzerland, U.K.: IUCN, While formerly known simply as the bottlenose dolphin, this term is now applied to the genus ''Tursiops'' as a whole. As considerable genetic variation has been described within this species, even between neighboring populations, many experts think additional species may be recognized. Taxon ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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