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Molecular Genealogy Research Project
The Sorenson Molecular Genealogy Foundation (SMGF) was an independent DNA and genealogical research institution with the goal of demonstrating how the peoples of the world are related. SMGF collected DNA samples and genealogical information from individuals across the globe to establish these connections. History SMGF originated in 1999 and was inspired by several conversations between inventor and philanthropist James LeVoy Sorenson and Brigham Young University professor Dr. Scott Woodward. Mr. Sorenson envisioned the development of a genetic-genealogical blueprint of all humankind. This blueprint, as developed by Dr. Woodward, would show how closely humans are related to one another, demonstrating the familial relationships between unique individuals. The collection of DNA samples and associated family pedigrees began in 2000, beginning first with Brigham Young University students, and quickly branching outside of Utah, then to the rest of the world. In 2003, SMGF moved it ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
James LeVoy Sorenson
James LeVoy Sorenson (July 30, 1921 – January 20, 2008) was an American businessman, the founder of Sorenson Companies, a parent company of 32 corporations. A noted philanthropist, he was the richest man in Utah with an estimated net worth of $4.5 billion at the time of his death. He donated his entire personal fortune to charity. Early life Sorenson was born in Rexburg, Idaho, the son of Joseph LeVoy and Emma Blaser Sorenson, and was of Swedish, Norwegian and Swiss ancestry. Career With only a high school diploma, he made a fortune in local real estate before expanding in other directions such as innovative technology. Sorenson holds roughly 60 patents, and is credited with a number of medical inventions including the disposable surgical mask and the disposable venous catheter. One of his companies, Sorenson Genomics, has also begun a genetic database known as the Sorenson Molecular Genealogy Foundation, and claims to be the only laboratory in the world to have succe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hypervariable Region
A hypervariable region (HVR) is a location within nuclear DNA or the D-loop of mitochondrial DNA in which base pairs of nucleotides repeat (in the case of nuclear DNA) or have substitutions (in the case of mitochondrial DNA). Changes or repeats in the hypervariable region are highly polymorphic. Mitochondrial There are two MITOCHONDRIAL hypervariable regions used in human mitochondrial genealogical DNA testing. HVR1 is considered a "low resolution" region and HVR2 is considered a "high resolution" region. Getting HVR1 and HVR2 DNA tests can help determine one's haplogroup. In the revised Cambridge Reference Sequence of the human mitogenome, the most variable sites of HVR1 are numbered 16024-16383 (this subsequence is called HVR-I), and the most variable sites of HVR2 are numbered 57-372 (''i.e.,'' HVR-II) and 438-574 (''i.e.,'' HVR-III).''PhyloTree mt''"Annotated mtDNA reference sequences: revised Cambridge Reference Sequence (rCRS)" Retrieved on 4 February 2016. In some bony f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetics Or Genomics Research Institutions
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinians, Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Phenotypic trait, Trait inheritance and Molecular genetics, molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the Cell (biolo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Research Institutes In Utah
Research is " creative and systematic work undertaken to increase the stock of knowledge". It involves the collection, organization and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to controlling sources of bias and error. These activities are characterized by accounting and controlling for biases. A research project may be an expansion on past work in the field. To test the validity of instruments, procedures, or experiments, research may replicate elements of prior projects or the project as a whole. The primary purposes of basic research (as opposed to applied research) are documentation, discovery, interpretation, and the research and development (R&D) of methods and systems for the advancement of human knowledge. Approaches to research depend on epistemologies, which vary considerably both within and between humanities and sciences. There are several forms of research: scientific, humanities, artistic, econom ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetic Genealogy
Genetic genealogy is the use of genealogical DNA tests, i.e., DNA profiling and DNA testing, in combination with traditional genealogical methods, to infer genetic relationships between individuals. This application of genetics came to be used by family historians in the 21st century, as DNA tests became affordable. The tests have been promoted by amateur groups, such as surname study groups or regional genealogical groups, as well as research projects such as the Genographic Project. As of 2019, about 30 million people had been tested. As the field developed, the aims of practitioners broadened, with many seeking knowledge of their ancestry beyond the recent centuries, for which traditional pedigrees can be constructed. History The investigation of surnames in genetics can be said to go back to George Darwin, a son of Charles Darwin and Charles' first cousin Emma Darwin. In 1875, George Darwin used surnames to estimate the frequency of first-cousin marriages and calculated t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Msnbc
MSNBC (originally the Microsoft National Broadcasting Company) is an American news-based pay television cable channel. It is owned by NBCUniversala subsidiary of Comcast. Headquartered in New York City, it provides news coverage and political commentary. As of September 2018, approximately 87 million households in the United States (90.7 percent of pay television subscribers) were receiving MSNBC. In 2019, MSNBC ranked second among basic cable networks averaging 1.8 million viewers, behind rival Fox News, averaging 2.5 million viewers. MSNBC and its website were founded in 1996 under a partnership between Microsoft and General Electric's NBC unit, hence the network's naming. Microsoft divested itself of its stakes in the MSNBC channel in 2005 and its stakes in msnbc.com in July 2012. The general news site was rebranded as NBCNews.com, and a new msnbc.com was created as the online home of the cable channel. In the late summer of 2015, MSNBC revamped its programming by entering ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
USA Today
''USA Today'' (stylized in all uppercase) is an American daily middle-market newspaper and news broadcasting company. Founded by Al Neuharth on September 15, 1982, the newspaper operates from Gannett's corporate headquarters in Tysons, Virginia. Its newspaper is printed at 37 sites across the United States and at five additional sites internationally. The paper's dynamic design influenced the style of local, regional, and national newspapers worldwide through its use of concise reports, colorized images, Infographic, informational graphics, and inclusion of popular culture stories, among other distinct features. With an average print circulation of 159,233 as of 2022, a digital-only subscriber base of 504,000 as of 2019, and an approximate daily readership of 2.6 million, ''USA Today'' is ranked as the first by circulation on the list of newspapers in the United States. It has been shown to maintain a generally center-left audience, in regards to political persuasion. ''US ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electronic Frontier Foundation
The Electronic Frontier Foundation (EFF) is an international non-profit digital rights group based in San Francisco, California. The foundation was formed on 10 July 1990 by John Gilmore, John Perry Barlow and Mitch Kapor to promote Internet civil liberties. The EFF provides funds for legal defense in court, presents '' amicus curiae'' briefs, defends individuals and new technologies from what it considers abusive legal threats, works to expose government malfeasance, provides guidance to the government and courts, organizes political action and mass mailings, supports some new technologies which it believes preserve personal freedoms and online civil liberties, maintains a database and web sites of related news and information, monitors and challenges potential legislation that it believes would infringe on personal liberties and fair use and solicits a list of what it considers abusive patents with intentions to defeat those that it considers without merit. History Fou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Business Wire
Business Wire is an American company that disseminates full-text press releases from thousands of companies and organizations worldwide to news media, financial markets, disclosure systems, investors, information web sites, databases, bloggers, social networks and other audiences. It is a subsidiary of Berkshire Hathaway. History Business Wire was founded in 1961 by Lorry I. Lokey. It started by sending releases to 16 media outlets in California. Business Wire launched its website in May 1995. In 2000, ahead of its main competitor PR Newswire, Business Wire ended the practice of distributing news to financial outlets 15 minutes before anyone else, to provide immediate, equal access to company information as noted by the SEC's fair disclosure regulation (Reg FD). Business Wire's first wholly owned European operation launched in 2001, with the opening of an office in London. On June 1, 2005, Business Wire entered the German Ad-Hoc market with a disclosure network for companies with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MSNBC
MSNBC (originally the Microsoft National Broadcasting Company) is an American news-based pay television cable channel. It is owned by NBCUniversala subsidiary of Comcast. Headquartered in New York City, it provides news coverage and political commentary. As of September 2018, approximately 87 million households in the United States (90.7 percent of pay television subscribers) were receiving MSNBC. In 2019, MSNBC ranked second among basic cable networks averaging 1.8 million viewers, behind rival Fox News, averaging 2.5 million viewers. MSNBC and its website were founded in 1996 under a partnership between Microsoft and General Electric's NBC unit, hence the network's naming. Microsoft divested itself of its stakes in the MSNBC channel in 2005 and its stakes in msnbc.com in July 2012. The general news site was rebranded as NBCNews.com, and a new msnbc.com was created as the online home of the cable channel. In the late summer of 2015, MSNBC revamped its programming by entering ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cambridge Reference Sequence
The Cambridge Reference Sequence (CRS) for human mitochondrial DNA was first announced in 1981. A group led by Fred Sanger at the University of Cambridge had sequenced the mitochondrial genome of one woman of European descent during the 1970s, determining it to have a length of 16,569 base pairs (0.0006% of the nuclear human genome) containing some 37 genes and published this sequence in 1981. When other researchers repeated the sequencing, some striking discrepancies were noted. The original published sequence included eleven errors, including one extra base pair in position 3107, and incorrect assignments of single base pairs. Some of these were the result of contamination with bovine and HeLa specimens. The corrected revised CRS was published by Andrews et al. in 1999. (The original nucleotide numbering was retained to avoid confusion.) The reference sequence belongs to European haplogroup H2a2a1. The revised CRS is designated as rCRS. It is deposited in the GenBank NCBI d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Single-nucleotide Polymorphism
In genetics, a single-nucleotide polymorphism (SNP ; plural SNPs ) is a germline substitution of a single nucleotide at a specific position in the genome. Although certain definitions require the substitution to be present in a sufficiently large fraction of the population (e.g. 1% or more), many publications do not apply such a frequency threshold. For example, at a specific base position in the human genome, the G nucleotide may appear in most individuals, but in a minority of individuals, the position is occupied by an A. This means that there is a SNP at this specific position, and the two possible nucleotide variations – G or A – are said to be the alleles for this specific position. SNPs pinpoint differences in our susceptibility to a wide range of diseases, for example age-related macular degeneration (a common SNP in the CFH gene is associated with increased risk of the disease) or nonalcoholic fatty liver disease (a SNP in the PNPLA3 gene is associated with inc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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