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Mimivirus Svg
''Mimivirus'' is a genus of giant viruses, in the family ''Mimiviridae''. Amoeba serve as their natural hosts. This genus contains a single identified species named ''Acanthamoeba polyphaga mimivirus'' (APMV). It also refers to a group of phylogenetically related large viruses. In colloquial speech, APMV is more commonly referred to as just "mimivirus". Mimivirus, short for "mimicking microbe", is so called to reflect its large size and apparent Gram-staining properties. Mimivirus has a large and complex genome compared with most other viruses. Until 2013, when a larger virus ''Pandoravirus'' was described, it had the largest capsid diameter of all known viruses. History APMV was discovered accidentally in 1992 within the amoeba ''Acanthamoeba polyphaga'', after which it is named, during research into legionellosis by researchers from Marseille and Leeds. The virus was observed in a Gram stain and mistakenly thought to be a Gram-positive bacterium. As a consequence it was name ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sputnik Virophage
''Mimivirus-dependent virus Sputnik'' (from Russian "satellite") is a subviral agent that reproduces in amoeba cells that are already infected by a certain helper virus; Sputnik uses the helper virus's machinery for reproduction and inhibits replication of the helper virus. It is known as a virophage, in analogy to the term ''bacteriophage''. Viruses like Sputnik that depend on co-infection of the host cell by helper viruses are known as satellite viruses. At its discovery in a Paris water-cooling tower in 2008, Sputnik was the first known satellite virus that inhibited replication of its helper virus and thus acted as a parasite of that virus. In analogy, it was called a ''virophage''. Sputnik virophages were found infecting giant viruses of ''Mimiviridae'' group A. However, they are able to grow in amoebae infected by ''Mimiviridae'' of any of the groups A, B, and C. Virology Sputnik was first isolated in 2008 from a sample obtained from humans; it was harvested from the c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mimivirus Svg
''Mimivirus'' is a genus of giant viruses, in the family ''Mimiviridae''. Amoeba serve as their natural hosts. This genus contains a single identified species named ''Acanthamoeba polyphaga mimivirus'' (APMV). It also refers to a group of phylogenetically related large viruses. In colloquial speech, APMV is more commonly referred to as just "mimivirus". Mimivirus, short for "mimicking microbe", is so called to reflect its large size and apparent Gram-staining properties. Mimivirus has a large and complex genome compared with most other viruses. Until 2013, when a larger virus ''Pandoravirus'' was described, it had the largest capsid diameter of all known viruses. History APMV was discovered accidentally in 1992 within the amoeba ''Acanthamoeba polyphaga'', after which it is named, during research into legionellosis by researchers from Marseille and Leeds. The virus was observed in a Gram stain and mistakenly thought to be a Gram-positive bacterium. As a consequence it was name ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gram Stain
In microbiology and bacteriology, Gram stain (Gram staining or Gram's method), is a method of staining used to classify bacterial species into two large groups: gram-positive bacteria and gram-negative bacteria. The name comes from the Danish bacteriologist Hans Christian Gram, who developed the technique in 1884. Gram staining differentiates bacteria by the chemical and physical properties of their cell walls. Gram-positive cells have a thick layer of peptidoglycan in the cell wall that retains the primary stain, crystal violet. Gram-negative cells have a thinner peptidoglycan layer that allows the crystal violet to wash out on addition of ethanol. They are stained pink or red by the counterstain, commonly safranin or fuchsine. Lugol's iodine solution is always added after addition of crystal violet to strengthen the bonds of the stain with the cell membrane. Gram staining is almost always the first step in the preliminary identification of a bacterial organism. While Gram s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Legionellosis
Legionnaires' disease is a form of atypical pneumonia caused by any species of ''Legionella'' bacteria, quite often '' Legionella pneumophila''. Signs and symptoms include cough, shortness of breath, high fever, muscle pains, and headaches. Nausea, vomiting, and diarrhea may also occur. This often begins 2–10 days after exposure. A legionellosis is any disease caused by ''Legionella'', including Legionnaires' disease (a pneumonia), Pontiac fever (a nonpneumonia illness), and Pittsburgh pneumonia, but Legionnaires' disease is the most common, so mentions of legionellosis often refer to Legionnaires' disease. The bacterium is found naturally in fresh water. It can contaminate hot water tanks, hot tubs, and cooling towers of large air conditioners. It is usually spread by breathing in mist that contains the bacteria. It can also occur when contaminated water is aspirated. It typically does not spread directly between people, and most people who are exposed do not become infect ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acanthamoeba
''Acanthamoeba'' is a genus of amoeboid, amoebae that are commonly recovered from soil, fresh water, and other habitat (ecology), habitats. ''Acanthamoeba'' has two evolutive forms, the metabolically active trophozoite and a dormant, stress-resistant cyst. Trophozoites are small, usually 15 to 25 μm in length and amoeboid in shape. In nature, ''Acanthamoeba'' species are free-living bacterivores, but in certain situations, they can cause infections (acanthamebiasis) in humans and other animals. Distribution ''Acanthamoeba'' spp. are among the most prevalent protozoa found in the environment. They are distributed worldwide, and have been isolated from soil, air, sewage, seawater, chlorinated swimming pools, domestic tap water, bottled water, dental treatment units, hospitals, air-conditioning units, and contact lens cases. Additionally, they have been isolated from human skin, nasal cavities, throats, and intestines, as well as plants and other mammals. Role in disease Diseas ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amoeba
An amoeba (; less commonly spelled ameba or amœba; plural ''am(o)ebas'' or ''am(o)ebae'' ), often called an amoeboid, is a type of Cell (biology), cell or unicellular organism with the ability to alter its shape, primarily by extending and retracting pseudopodia, pseudopods. Amoebae do not form a single Taxonomy (biology), taxonomic group; instead, they are found in every major Lineage (evolution), lineage of eukaryote, eukaryotic organisms. Amoeboid cells occur not only among the protozoa, but also in fungi, algae, and animals. Microbiologists often use the terms "amoeboid" and "amoeba" interchangeably for any organism that exhibits amoeboid movement. In older classification systems, most amoebae were placed in the Class (biology), class or subphylum Sarcodina, a grouping of Unicellular organism, single-celled organisms that possess pseudopods or move by protoplasmic flow. However, molecular phylogenetic studies have shown that Sarcodina is not a monophyletic group whose memb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Capsid
A capsid is the protein shell of a virus, enclosing its genetic material. It consists of several oligomeric (repeating) structural subunits made of protein called protomers. The observable 3-dimensional morphological subunits, which may or may not correspond to individual proteins, are called capsomeres. The proteins making up the capsid are called capsid proteins or viral coat proteins (VCP). The capsid and inner genome is called the nucleocapsid. Capsids are broadly classified according to their structure. The majority of the viruses have capsids with either helical or icosahedral structure. Some viruses, such as bacteriophages, have developed more complicated structures due to constraints of elasticity and electrostatics. The icosahedral shape, which has 20 equilateral triangular faces, approximates a sphere, while the helical shape resembles the shape of a spring, taking the space of a cylinder but not being a cylinder itself. The capsid faces may consist of one or more ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pandoravirus
''Pandoravirus'' is a genus of giant virus, first discovered in 2013. It is the second largest in physical size of any known viral genus. Pandoraviruses have double stranded DNA genomes, with the largest genome size (2.5 million base pairs) of any known viral genus. Discovery The discovery of Pandoraviruses by a team of French scientists, led by husband and wife Jean-Michel Claverie and Chantal Abergel, was announced in a report in the journal ''Science'' in July 2013. Other scientists had previously observed the pandoravirus particles, but owing to their enormous size they were not expected to be viruses. Patrick Scheid, a parasitologist from the Central Institute of the Bundeswehr Medical Service in Koblenz, Germany, found one in 2008, in an amoeba living in the contact lens of a woman with keratitis. Its development within the amoebal host was documented extensively. Unlike in other cases with such giant viruses, the large particles within ''Acanthamoeba'' were not mistak ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genome
In the fields of molecular biology and genetics, a genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as regulatory sequences (see non-coding DNA), and often a substantial fraction of 'junk' DNA with no evident function. Almost all eukaryotes have mitochondria and a small mitochondrial genome. Algae and plants also contain chloroplasts with a chloroplast genome. The study of the genome is called genomics. The genomes of many organisms have been sequenced and various regions have been annotated. The International Human Genome Project reported the sequence of the genome for ''Homo sapiens'' in 200The Human Genome Project although the initial "finished" sequence was missing 8% of the genome consisting mostly of repetitive sequences. With advancements in technology that could handle sequenci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gram-staining
In microbiology and bacteriology, Gram stain (Gram staining or Gram's method), is a method of staining used to classify bacterial species into two large groups: gram-positive bacteria and gram-negative bacteria. The name comes from the Danish bacteriologist Hans Christian Gram, who developed the technique in 1884. Gram staining differentiates bacteria by the chemical and physical properties of their cell walls. Gram-positive cells have a thick layer of peptidoglycan in the cell wall that retains the primary stain, crystal violet. Gram-negative cells have a thinner peptidoglycan layer that allows the crystal violet to wash out on addition of ethanol. They are stained pink or red by the counterstain, commonly safranin or fuchsine. Lugol's iodine solution is always added after addition of crystal violet to strengthen the bonds of the stain with the cell membrane. Gram staining is almost always the first step in the preliminary identification of a bacterial organism. While Gram stain ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Virology Journal
''Virology Journal'' is an open-access peer-reviewed medical journal published by BioMed Central. It publishes research related to viruses and the prevention of viral infection (including vaccination, the use of antiviral agents, and gene therapy). The journal was established in 2004 with Robert Garry (Tulane University) as founding editor-in-chief and has been edited by Linfa Wang since 2012. It aims to cover rapid communications amongst virologists. Controversy On 21 July 2010, ''Virology Journal'' published an article entitled "Influenza or not influenza: Analysis of a case of high fever that happened 2000 years ago in Biblical time". According to and , the mother-in-law of Simon Peter "lay sick" with a febrile illness. Jesus then took her by the hand and the fever immediately left. This is also described in . The authors rule out that the woman was possessed by demons, and conclude that she was struck with influenza as "the fever retreated instantaneously. This implies t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amoeba
An amoeba (; less commonly spelled ameba or amœba; plural ''am(o)ebas'' or ''am(o)ebae'' ), often called an amoeboid, is a type of Cell (biology), cell or unicellular organism with the ability to alter its shape, primarily by extending and retracting pseudopodia, pseudopods. Amoebae do not form a single Taxonomy (biology), taxonomic group; instead, they are found in every major Lineage (evolution), lineage of eukaryote, eukaryotic organisms. Amoeboid cells occur not only among the protozoa, but also in fungi, algae, and animals. Microbiologists often use the terms "amoeboid" and "amoeba" interchangeably for any organism that exhibits amoeboid movement. In older classification systems, most amoebae were placed in the Class (biology), class or subphylum Sarcodina, a grouping of Unicellular organism, single-celled organisms that possess pseudopods or move by protoplasmic flow. However, molecular phylogenetic studies have shown that Sarcodina is not a monophyletic group whose memb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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