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Sputnik Virophage
''Mimivirus-dependent virus Sputnik'' (from Russian "satellite") is a subviral agent that reproduces in amoeba cells that are already infected by a certain helper virus; Sputnik uses the helper virus's machinery for reproduction and inhibits replication of the helper virus. It is known as a virophage, in analogy to the term ''bacteriophage''. Viruses like Sputnik that depend on co-infection of the host cell by helper viruses are known as satellite viruses. At its discovery in a Paris water-cooling tower in 2008, Sputnik was the first known satellite virus that inhibited replication of its helper virus and thus acted as a parasite of that virus. In analogy, it was called a ''virophage''. Sputnik virophages were found infecting giant viruses of ''Mimiviridae'' group A. However, they are able to grow in amoebae infected by ''Mimiviridae'' of any of the groups A, B, and C. Virology Sputnik was first isolated in 2008 from a sample obtained from humans; it was harvested from ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Giant Mimivirus With Satellite Sputnik Virophages
In folklore, giants (from Ancient Greek: ''gigas'', cognate giga-) are beings of human-like appearance, but are at times prodigious in size and strength or bear an otherwise notable appearance. The word ''giant'' is first attested in 1297 from Robert of Gloucester's chronicle. It is derived from the ''Gigantes'' ( grc-gre, Γίγαντες) of Greek mythology. Fairy tales such as ''Jack the Giant Killer'' have formed the modern perception of giants as dimwitted ogres, sometimes said to eat humans, while other giants tend to eat the livestock. The antagonist in ''Jack and the Beanstalk'' is often described as a giant. In some more recent portrayals, like those of Jonathan Swift and Roald Dahl, some giants are both intelligent and friendly. Literary and cultural analysis Giants appear in the folklore of cultures worldwide as they represent a relatively simple concept. Representing the human body enlarged to the point of being monstrous, giants evoke terror and remind humans of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eukarya
Eukaryotes () are organisms whose cells have a nucleus. All animals, plants, fungi, and many unicellular organisms, are Eukaryotes. They belong to the group of organisms Eukaryota or Eukarya, which is one of the three domains of life. Bacteria and Archaea (both prokaryotes) make up the other two domains. The eukaryotes are usually now regarded as having emerged in the Archaea or as a sister of the Asgard archaea. This implies that there are only two domains of life, Bacteria and Archaea, with eukaryotes incorporated among archaea. Eukaryotes represent a small minority of the number of organisms, but, due to their generally much larger size, their collective global biomass is estimated to be about equal to that of prokaryotes. Eukaryotes emerged approximately 2.3–1.8 billion years ago, during the Proterozoic eon, likely as flagellated phagotrophs. Their name comes from the Greek εὖ (''eu'', "well" or "good") and κάρυον (''karyon'', "nut" or "kernel"). Eukaryo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lavidaviridae
Virophages are small, double-stranded DNA viral phages that require the co-infection of another virus. The co-infecting viruses are typically giant viruses. Virophages rely on the viral replication factory of the co-infecting giant virus for their own replication. One of the characteristics of virophages is that they have a parasitic relationship with the co-infecting virus. Their dependence upon the giant virus for replication often results in the deactivation of the giant viruses. The virophage may improve the recovery and survival of the host organism. Unlike satellite viruses, virophages have a parasitic effect on their co-infecting virus. Virophages have been observed to render a giant virus inactive and thereby improve the condition of the host organism. All known virophages are grouped into the family ''Lavidaviridae'' (from "large virus dependent or associated" + -viridae). Discovery The first virophage was discovered in a cooling tower in Paris, France in 2008. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sputnikvirus
''Mimivirus-dependent virus Sputnik'' (from Russian "satellite") is a subviral agent that reproduces in amoeba cells that are already infected by a certain helper virus; Sputnik uses the helper virus's machinery for reproduction and inhibits replication of the helper virus. It is known as a virophage, in analogy to the term ''bacteriophage''. Viruses like Sputnik that depend on co-infection of the host cell by helper viruses are known as satellite viruses. At its discovery in a Paris water-cooling tower in 2008, Sputnik was the first known satellite virus that inhibited replication of its helper virus and thus acted as a parasite of that virus. In analogy, it was called a ''virophage''. Sputnik virophages were found infecting giant viruses of ''Mimiviridae'' group A. However, they are able to grow in amoebae infected by ''Mimiviridae'' of any of the groups A, B, and C. Virology Sputnik was first isolated in 2008 from a sample obtained from humans; it was harvested from the c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
DNA Virus
A DNA virus is a virus that has a genome made of deoxyribonucleic acid (DNA) that is replicated by a DNA polymerase. They can be divided between those that have two strands of DNA in their genome, called double-stranded DNA (dsDNA) viruses, and those that have one strand of DNA in their genome, called single-stranded DNA (ssDNA) viruses. dsDNA viruses primarily belong to two realms: ''Duplodnaviria'' and ''Varidnaviria'', and ssDNA viruses are almost exclusively assigned to the realm ''Monodnaviria'', which also includes some dsDNA viruses. Additionally, many DNA viruses are unassigned to higher taxa. Reverse transcribing viruses, which have a DNA genome that is replicated through an RNA intermediate by a reverse transcriptase, are classified into the kingdom ''Pararnavirae'' in the realm ''Riboviria''. DNA viruses are ubiquitous worldwide, especially in marine environments where they form an important part of marine ecosystems, and infect both prokaryotes and eukaryotes. They a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lateral Gene Transfer
Horizontal gene transfer (HGT) or lateral gene transfer (LGT) is the movement of genetic material between unicellular and/or multicellular organisms other than by the ("vertical") transmission of DNA from parent to offspring (reproduction). HGT is an important factor in the evolution of many organisms. HGT is influencing scientific understanding of higher order evolution while more significantly shifting perspectives on bacterial evolution. Horizontal gene transfer is the primary mechanism for the spread of antibiotic resistance in bacteria, and plays an important role in the evolution of bacteria that can degrade novel compounds such as human-created pesticides and in the evolution, maintenance, and transmission of virulence. It often involves temperate bacteriophages and plasmids. Genes responsible for antibiotic resistance in one species of bacteria can be transferred to another species of bacteria through various mechanisms of HGT such as transformation, transduction ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Global Ocean Sampling Expedition
The Global Ocean Sampling Expedition (GOS) is an ocean exploration genome project whose goal is to assess genetic diversity in marine microbial communities and to understand their role in nature's fundamental processes. It was begun as a Sargasso Sea pilot sampling project in August 2003; Craig Venter announced the full expedition on 4 March 2004. The two-year journey, which used Craig Venter's personal yacht, originated in Halifax, Canada, circumnavigated the globe and terminated in the U.S. in January 2006. The expedition sampled water from Halifax, Nova Scotia to the Eastern Tropical Pacific Ocean. During 2007, sampling continued along the west coast of North America. Data analysis The GOS datasets were submitted to both NCBI [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ATPase
ATPases (, Adenosine 5'-TriPhosphatase, adenylpyrophosphatase, ATP monophosphatase, triphosphatase, SV40 T-antigen, ATP hydrolase, complex V (mitochondrial electron transport), (Ca2+ + Mg2+)-ATPase, HCO3−-ATPase, adenosine triphosphatase) are a class of enzymes that catalyze the decomposition of ATP into ADP and a free phosphate ion or the inverse reaction. This dephosphorylation reaction releases energy, which the enzyme (in most cases) harnesses to drive other chemical reactions that would not otherwise occur. This process is widely used in all known forms of life. Some such enzymes are integral membrane proteins (anchored within biological membranes), and move solutes across the membrane, typically against their concentration gradient. These are called transmembrane ATPases. Functions Transmembrane ATPases import metabolites necessary for cell metabolism and export toxins, wastes, and solutes that can hinder cellular processes. An important example is the sodium-po ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Annual Review Of Genetics
The ''Annual Review of Genetics'' is an annual peer-reviewed scientific review journal published by Annual Reviews. It was established in 1967 and covers all topics related to the genetics of viruses, bacteria, fungi, plants, and animals, including humans. The current editor is Tatjana Piotrowski. As of 2021, ''Journal Citation Reports'' gives the journal a 2020 impact factor of 16.830, ranking it fourth out of 175 journals in the category "Genetics & Heredity". History In 1965, the nonprofit publisher Annual Reviews surveyed geneticists to determine if there was a need for an annual journal that published review articles about recent developments in the field of genetics. Responses to the survey were favorable, with the first volume of the ''Annual Review of Genetics'' published two years later in 1967. Its inaugural editor was Herschel L. Roman. As of 2020, it was published both in print and electronically. It defines its scope as covering various aspects of genetics, includin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hairpin Loop
Stem-loop intramolecular base pairing is a pattern that can occur in single-stranded RNA. The structure is also known as a hairpin or hairpin loop. It occurs when two regions of the same strand, usually complementary in nucleotide sequence when read in opposite directions, base-pair to form a double helix that ends in an unpaired loop. The resulting structure is a key building block of many RNA secondary structures. As an important secondary structure of RNA, it can direct RNA folding, protect structural stability for messenger RNA (mRNA), provide recognition sites for RNA binding proteins, and serve as a substrate for enzymatic reactions. Formation and stability The formation of a stem-loop structure is dependent on the stability of the resulting helix and loop regions. The first prerequisite is the presence of a sequence that can fold back on itself to form a paired double helix. The stability of this helix is determined by its length, the number of mismatches or bulges it c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
AT-content
In molecular biology and genetics, GC-content (or guanine-cytosine content) is the percentage of nitrogenous bases in a DNA or RNA molecule that are either guanine (G) or cytosine (C). This measure indicates the proportion of G and C bases out of an implied four total bases, also including adenine and thymine in DNA and adenine and uracil in RNA. GC-content may be given for a certain fragment of DNA or RNA or for an entire genome. When it refers to a fragment, it may denote the GC-content of an individual gene or section of a gene (domain), a group of genes or gene clusters, a non-coding region, or a synthetic oligonucleotide such as a primer. Structure Qualitatively, guanine (G) and cytosine (C) undergo a specific hydrogen bonding with each other, whereas adenine (A) bonds specifically with thymine (T) in DNA and with uracil (U) in RNA. Quantitatively, each GC base pair is held together by three hydrogen bonds, while AT and AU base pairs are held together by two hydrogen bonds. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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