Millettia Nitida
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Millettia Nitida
''Callerya nitida'' is a species of flowering plant in the family Fabaceae, native to south-central and southeast mainland China, Hainan and Taiwan. It was first described by George Bentham in 1842 as ''Millettia nitida''. ''Callerya nitida'' produces a number of compounds among which genistein-8-C-β-D-apiofuranosyl-(1→6)-O-β-D-glucopyranoside, calycosin, isoliquiritigenin, formononetin, gliricidin, 8-O-methylretusin, dihydrokaempferol, biochanin, afromosin and hirsutissimiside F interact with thrombin, while sphaerobioside, formononetin-7-O-β-D-apiofuranosyl-(1→6)-O-β-d-glucopyranoside, genistein-5-methylether-7-O-α-L-rhamnopyranosyl-(1→6)-O-β-D-glucopyranoside, retusin-7,8-O-β-D-diglucopyranoside, symplocoside, ononin, genistin, afromosin-7-O-β-D-glucopyranoside, lanceolarin, liquiritigenin Liquiritigenin is a flavanone that was isolated from ''Glycyrrhiza uralensis'', and is found in a variety of plants, including ''Glycyrrhiza glabra'' (licorice ...
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Hong Kong
Hong Kong ( (US) or (UK); , ), officially the Hong Kong Special Administrative Region of the People's Republic of China ( abbr. Hong Kong SAR or HKSAR), is a city and special administrative region of China on the eastern Pearl River Delta in South China. With 7.5 million residents of various nationalities in a territory, Hong Kong is one of the most densely populated places in the world. Hong Kong is also a major global financial centre and one of the most developed cities in the world. Hong Kong was established as a colony of the British Empire after the Qing Empire ceded Hong Kong Island from Xin'an County at the end of the First Opium War in 1841 then again in 1842.. The colony expanded to the Kowloon Peninsula in 1860 after the Second Opium War and was further extended when Britain obtained a 99-year lease of the New Territories in 1898... British Hong Kong was occupied by Imperial Japan from 1941 to 1945 during World War II; British administration resume ...
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Thrombin
Thrombin (, ''fibrinogenase'', ''thrombase'', ''thrombofort'', ''topical'', ''thrombin-C'', ''tropostasin'', ''activated blood-coagulation factor II'', ''blood-coagulation factor IIa'', ''factor IIa'', ''E thrombin'', ''beta-thrombin'', ''gamma-thrombin'') is a serine protease, an enzyme that, in humans, is encoded by the ''F2'' gene. Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the clotting process. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions. History After the description of fibrinogen and fibrin, Alexander Schmidt hypothesised the existence of an enzyme that converts fibrinogen into fibrin in 1872. Prothrombin was discovered by Pekelharing in 1894. Physiology Synthesis Thrombin is produced by the enzymatic cleavage of two sites on prothrombin by activated Factor X (Xa). The activity of factor Xa is greatly ...
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Flora Of South-Central China
Flora is all the plant life present in a particular region or time, generally the naturally occurring (indigenous) native plants. Sometimes bacteria and fungi are also referred to as flora, as in the terms ''gut flora'' or '' skin flora''. Etymology The word "flora" comes from the Latin name of Flora, the goddess of plants, flowers, and fertility in Roman mythology. The technical term "flora" is then derived from a metonymy of this goddess at the end of the sixteenth century. It was first used in poetry to denote the natural vegetation of an area, but soon also assumed the meaning of a work cataloguing such vegetation. Moreover, "Flora" was used to refer to the flowers of an artificial garden in the seventeenth century. The distinction between vegetation (the general appearance of a community) and flora (the taxonomic composition of a community) was first made by Jules Thurmann (1849). Prior to this, the two terms were used indiscriminately.Thurmann, J. (1849). ''Essai de Phy ...
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Wisterieae
Wisterieae is a Tribe (biology), tribe of flowering plants in the bean family Fabaceae. The tribe was first described in 1994 for the sole genus ''Wisteria'', but was greatly expanded in 2019 to include 13 genera, six of which were new. Five had previously been placed in the tribe Millettieae. Members of the tribe are climbers of various kinds. Some, like ''Wisteria'', are cultivated for their flowers. Description Members of the tribe Wisterieae are either woody lianas or sprawling climbing shrubs. All species have their flowers arranged in either true panicles or true racemes (as opposed to pseudopanicles or pseudoracemes). The tribe belongs to the Inverted repeat-lacking clade; all genera lack one 25 Base pair#Length measurements, kilobase long copy of the Chloroplast_DNA#Inverted_repeats, inverted repeat in the chloroplast genome, distinguishing them from genera in the tribe Millettieae, which do not lack this inverted repeat. Taxonomy The tribe was established in 1994 by X. Y ...
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Royal Botanic Gardens, Kew
Royal Botanic Gardens, Kew is a non-departmental public body in the United Kingdom sponsored by the Department for Environment, Food and Rural Affairs. An internationally important botanical research and education institution, it employs 1,100 staff. Its board of trustees is chaired by Dame Amelia Fawcett. The organisation manages botanic gardens at Kew in Richmond upon Thames in south-west London, and at Wakehurst, a National Trust property in Sussex which is home to the internationally important Millennium Seed Bank, whose scientists work with partner organisations in more than 95 countries. Kew, jointly with the Forestry Commission, founded Bedgebury National Pinetum in Kent in 1923, specialising in growing conifers. In 1994, the Castle Howard Arboretum Trust, which runs the Yorkshire Arboretum, was formed as a partnership between Kew and the Castle Howard Estate. In 2019, the organisation had 2,316,699 public visitors at Kew, and 312,813 at Wakehurst. Its site at Kew ...
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Plants Of The World Online
Plants of the World Online (POWO) is an online database published by the Royal Botanic Gardens, Kew. It was launched in March 2017 with the ultimate aim being "to enable users to access information on all the world's known seed-bearing plants by 2020". The initial focus was on tropical African Floras, particularly Flora Zambesiaca, Flora of West Tropical Africa and Flora of Tropical East Africa. The database uses the same taxonomical source as Kew's World Checklist of Selected Plant Families, which is the International Plant Names Index, and the World Checklist of Vascular Plants (WCVP). POWO contains 1,234,000 global plant names and 367,600 images. See also *Australian Plant Name Index *Convention on Biological Diversity *World Flora Online *Tropicos Tropicos is an online botanical database containing taxonomic information on plants, mainly from the Neotropical realm (Central, and South America). It is maintained by the Missouri Botanical Garden and was established over 25 y ...
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International Plant Names Index
The International Plant Names Index (IPNI) describes itself as "a database of the names and associated basic bibliographical details of seed plants, ferns and lycophytes." Coverage of plant names is best at the rank of species and genus. It includes basic bibliographical details associated with the names. Its goals include eliminating the need for repeated reference to primary sources for basic bibliographic information about plant names. The IPNI also maintains a list of standardized author abbreviations. These were initially based on Brummitt & Powell (1992), but new names and abbreviations are continually added. Description IPNI is the product of a collaboration between The Royal Botanic Gardens, Kew (Index Kewensis), The Harvard University Herbaria (Gray Herbarium Index), and the Australian National Herbarium ( APNI). The IPNI database is a collection of the names registered by the three cooperating institutions and they work towards standardizing the information. The stan ...
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Liquiritigenin
Liquiritigenin is a flavanone that was isolated from ''Glycyrrhiza uralensis'', and is found in a variety of plants, including ''Glycyrrhiza glabra'' (licorice). It is an estrogenic compound which acts as a selective agonist of the ERβ subtype of the estrogen receptor (ER), though it is also reported to act as an ERα partial agonist at sufficient concentrations. It also has a choleretic effect. Liquiritigenin,NADPH:oxygen oxidoreductase (hydroxylating, aryl migration) is an enzyme that uses liquiritigenin, O2, NADPH and H+ to produce 2,7,4'-trihydroxyisoflavanone, H2O, and NADP+. See also * Menerba * Prinaberel (ERB-041) * Diarylpropionitrile (DPN) * WAY-200070 * PHTPP * (R,R)-Tetrahydrochrysene ((R,R)-THC) * Propylpyrazoletriol (PPT) * Methylpiperidinopyrazole Methylpiperidinopyrazole (MPP) is a synthetic, nonsteroidal, and highly selective antagonist of ERα that is used in scientific research to study the function of this receptor. It has 200-fold selectivity for ERΠ...
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Genistin
Genistin is an isoflavone found in a number of dietary plants like soy and kudzu. It was first isolated in 1931 from the 90% methanol extract of a soybean meal, when it was found that hydrolysis with hydrochloric acid produced 1 mole each of genistein and glucose. Chemically it is the 7-O-beta-D-glucoside form of genistein and is the predominant form of the isoflavone naturally occurring in plants. In fact, studies in the 1970s revealed that 99% of the isoflavonoid compounds in soy are present as their glucosides. The glucosides are converted by digestive enzymes in the digestive system to exert their biological effects. Genistin is also converted to a more familiar genistein, thus, the biological activities including antiatherosclerotic, estrogenic and anticancer effects are analogous. Metabolism When ingested along the diet, genistin is readily converted to its aglycone form, genistein. It is hydrolyzed by removing the covalently bound glucose to form genistein and that genis ...
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Ononin
Ononin is an isoflavone glycoside, the 7-''O''-β-D-glucopyranoside of formononetin, which in turn is the 4'-''O''-methoxy derivative of the parent isoflavone daidzein. Natural sources Ononin is a major isoflavone found in a number of plants and herbs like soybean and Glycyrrhiza uralensis. Pharmacokinetics Intestinal bacterial metabolic pathways may include demethylation and deglycosylation. It follows that formation of formononetin and/or daidzein is possible. Pharmacodynamics An ''in vitro ''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called " test-tube experiments", these studies in biology ...'' anti-inflammatory effect on lipopolysaccharide (LPS)-induced inflammation has been demonstrated in one study. References {{Isoflavone O-methylated isoflavones Isoflavone glucosides ...
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