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McArdle Laboratory
The McArdle Laboratory for Cancer Research is a basic cancer research facility located on the University of Wisconsin–Madison campus in Madison, Wisconsin. It houses the university's Department of Oncology . The staff of the McArdle Laboratory numbers approximately 200. Twenty-eight faculty members lead research groups focused on various fields such as cancer virology, signal transduction, cell cycle, cancer genetics, and carcinogenesis. Peer-reviewed grants awarded on a competitive basis by agencies such as the National Cancer Institute, Department of Defense, American Cancer Society, and Susan G. Komen for the Cure provide the major source of research funds for the McArdle Laboratory. A small percentage of McArdle’s operating budget is provided by the State of Wisconsin. Private donations and bequests made directly to the McArdle Laboratory play a vital role in the support of the research carried out at the Laboratory. Founding faculty Harold P. Rusch, Roswell Boutwell, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Association For Cancer Research
The American Association for Cancer Research (AACR) is the world's oldest and largest professional association related to cancer research. Based in Philadelphia, the AACR focuses on all aspects of cancer research, including basic, clinical, and translational research into the etiology, prevention, diagnosis, and treatment of cancer. Founded in 1907 by 11 physicians and scientists, the organization now has more than 52,000 members in 130 countries and territories. The mission of the AACR is to prevent and cure cancer through research, education, communication, collaboration, science policy and advocacy, and funding for cancer research. History The AACR was founded on May 7, 1907 in Washington, DC as the "Association for Cancer Research" by a group of scientists consisting of four surgeons, five pathologists, and two biochemists. The founding members were Silas P. Beebe, George H. A. Clowes, William Coley, James Ewing, Harvey R. Gaylord, Robert B. Greenough, J. Collins War ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Causality
Causality (also referred to as causation, or cause and effect) is influence by which one event, process, state, or object (''a'' ''cause'') contributes to the production of another event, process, state, or object (an ''effect'') where the cause is partly responsible for the effect, and the effect is partly dependent on the cause. In general, a process has many causes, which are also said to be ''causal factors'' for it, and all lie in its past. An effect can in turn be a cause of, or causal factor for, many other effects, which all lie in its future. Some writers have held that causality is metaphysically prior to notions of time and space. Causality is an abstraction that indicates how the world progresses. As such a basic concept, it is more apt as an explanation of other concepts of progression than as something to be explained by others more basic. The concept is like those of agency and efficacy. For this reason, a leap of intuition may be needed to grasp it. Accordin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biochemistry
Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and metabolism. Over the last decades of the 20th century, biochemistry has become successful at explaining living processes through these three disciplines. Almost all areas of the life sciences are being uncovered and developed through biochemical methodology and research. Voet (2005), p. 3. Biochemistry focuses on understanding the chemical basis which allows biological molecules to give rise to the processes that occur within living cells and between cells,Karp (2009), p. 2. in turn relating greatly to the understanding of tissues and organs, as well as organism structure and function.Miller (2012). p. 62. Biochemistry is closely related to molecular biology, which is the study of the molecular mechanisms of biological phenomena.As ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carcinogens
A carcinogen is any substance, radionuclide, or radiation that promotes carcinogenesis (the formation of cancer). This may be due to the ability to damage the genome or to the disruption of cellular metabolic processes. Several radioactive substances are considered carcinogens, but their carcinogenic activity is attributed to the radiation, for example gamma rays and alpha particles, which they emit. Common examples of non-radioactive carcinogens are inhaled asbestos, certain dioxins, and tobacco smoke. Although the public generally associates carcinogenicity with synthetic chemicals, it is equally likely to arise from both natural and synthetic substances. Carcinogens are not necessarily immediately toxic; thus, their effect can be insidious. Carcinogens, as mentioned, are agents in the environment capable of contributing to cancer growth. Carcinogens can be categorized into two different types: activation-dependent and activation-independent, and each nature impacts their level ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Regulation Of Gene Expression
Regulation of gene expression, or gene regulation, includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA). Sophisticated programs of gene expression are widely observed in biology, for example to trigger developmental pathways, respond to environmental stimuli, or adapt to new food sources. Virtually any step of gene expression can be modulated, from Transcriptional regulation, transcriptional initiation, to RNA processing, and to the post-translational modification of a protein. Often, one gene regulator controls another, and so on, in a gene regulatory network. Gene regulation is essential for viruses, prokaryotes and eukaryotes as it increases the versatility and adaptability of an organism by allowing the cell to express protein when needed. Although as early as 1951, Barbara McClintock showed interaction between two genetic loci, Activator (''Ac'') and Dissociator (''Ds''), in the color f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Elizabeth C
Elizabeth or Elisabeth may refer to: People * Elizabeth (given name), a female given name (including people with that name) * Elizabeth (biblical figure), mother of John the Baptist Ships * HMS Elizabeth, HMS ''Elizabeth'', several ships * Elisabeth (schooner), ''Elisabeth'' (schooner), several ships * Elizabeth (freighter), ''Elizabeth'' (freighter), an American freighter that was wrecked off New York harbor in 1850; see Places Australia * City of Elizabeth ** Elizabeth, South Australia * Elizabeth Reef, a coral reef in the Tasman Sea United States * Elizabeth, Arkansas * Elizabeth, Colorado * Elizabeth, Georgia * Elizabeth, Illinois * Elizabeth, Indiana * Hopkinsville, Kentucky, originally known as Elizabeth * Elizabeth, Louisiana * Elizabeth Islands, Massachusetts * Elizabeth, Minnesota * Elizabeth, New Jersey, largest city with the name in the U.S. * Elizabeth City, North Carolina * Elizabeth (Charlotte neighborhood), North Carolina * Elizabeth, Pennsylvania * Elizabeth Tow ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scholarship
A scholarship is a form of financial aid awarded to students for further education. Generally, scholarships are awarded based on a set of criteria such as academic merit, diversity and inclusion, athletic skill, and financial need. Scholarship criteria usually reflect the values and goals of the donor of the award, and while scholarship recipients are not required to repay scholarships, the awards may require that the recipient continue to meet certain requirements during their period of support, such maintaining a minimum grade point average or engaging in a certain activity (e.g., playing on a school sports team for athletic scholarship holders). Scholarships also range in generosity; some range from covering partial tuition ranging all the way to a 'full-ride', covering all tuition, accommodation, housing and others. Some prestigious, highly competitive scholarships are well-known even outside the academic community, such as Fulbright Scholarship and the Rhodes Scholar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mcardle Laboratory For Cancer Research At The University Of Wisconsin
The surname McArdle or MacArdle was the twelfth most numerous in its homeland of County Monaghan in 1970. The surname in Irish is MacArdghail, from ''ardghal'', meaning 'high valour' or from the Irish "ardghail" meaning "tall foreigner" with roots "ard" meaning "tall" and "gail" meaning "foreigner", indicative of their original ancestor being a Viking or from Viking stock. The surname is also common in County Armagh and County Louth. They are a branch of the McMahon's of Oriel, descendants from 'Ardghail Mor MacMahon' (Irish name: ''Ardghail MacBriain MacMathghamhna''), who was chief of the MacMahons and King of Oriel from 1402 to 1416. They were based originally in the barony of Monaghan and a branch became sub-chiefs in County Armagh under the O'Neills of the Fews.http://www.ulsterancestry.com/irish-surnames.html People with the surname *Aidan McArdle, Irish actor *Andrea McArdle, Irish-American singer and actress *Angela McArdle, American Libertarian politician *Brian McArdle ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Günter Blobel
Günter Blobel (; May 21, 1936 – February 18, 2018) was a Silesian German and American biologist and 1999 Nobel Prize laureate in Physiology for the discovery that proteins have intrinsic signals that govern their transport and localization in the cell. Biography Günter Blobel was born in Waltersdorf in the Prussian Province of Lower Silesia, then located in eastern Germany. In January 1945 his family fled from native Silesia to Dresden to escape from the advancing Red Army. During the bombing of Dresden, Blobel, then 8, stayed with his family at a relative's farm to the west of the city. After the war, Blobel grew up and attended gymnasium in the Saxon town of Freiberg. He studied medicine and graduated from the University of Tübingen in 1960. After two years service in a medical internship, he moved to Madison, Wisconsin, following an older brother, enrolling in the University of Wisconsin–Madison and, joining the lab of Van R. Potter for his graduate work. Blobel matric ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oncology
Oncology is a branch of medicine that deals with the study, treatment, diagnosis and prevention of cancer. A medical professional who practices oncology is an ''oncologist''. The name's etymological origin is the Greek word ὄγκος (''ónkos''), meaning "tumor", "volume" or "mass". Oncology is concerned with: * The diagnosis of any cancer in a person (pathology) * Therapy (e.g. surgery, chemotherapy, radiotherapy and other modalities) * Follow-up of cancer patients after successful treatment * Palliative care of patients with terminal malignancies * Ethical questions surrounding cancer care * Screening efforts: ** of populations, or ** of the relatives of patients (in types of cancer that are thought to have a hereditary basis, such as breast cancer) Diagnosis Medical histories remain an important screening tool: the character of the complaints and nonspecific symptoms (such as fatigue, weight loss, unexplained anemia, fever of unknown origin, paraneoplastic phenome ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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