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Mark A. Smith
Mark Anthony Smith (August 15, 1965 – December 19, 2010) was a professor of pathology at Case Western Reserve University in Cleveland, Ohio, where he also served as the Director of Basic Science Research at the University Memory and Aging Center. At the time of his death, he had been serving as Executive Director of the American Aging Association. Smith served as Editor-in Chief of ''Journal of Alzheimer's Disease'' and also sat on the Editorial Board of over 20 leading journals including ''Science Translational Medicine'', '' Discovery Medicine'', ''Journal of Neurochemistry'', Journal of Pathology and ''The American Journal of Pathology''. He is recognized in the field of Alzheimer's disease research particularly for his work on oxidative stress, mitochondria dysfunction and cell cycle re-entry and, with a h-index of 73 and over 800 peer-review articles and reviews that have received over 21,000 citations, he was named as one of the top Alzheimer's disease researchers in th ...
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Leicester
Leicester ( ) is a city status in the United Kingdom, city, Unitary authorities of England, unitary authority and the county town of Leicestershire in the East Midlands of England. It is the largest settlement in the East Midlands. The city lies on the River Soar and close to the eastern end of the National Forest, England, National Forest. It is situated to the north-east of Birmingham and Coventry, south of Nottingham and west of Peterborough. The population size has increased by 38,800 ( 11.8%) from around 329,800 in 2011 to 368,600 in 2021 making it the most populous municipality in the East Midlands region. The associated Urban area#United Kingdom, urban area is also the 11th most populous in England and the List of urban areas in the United Kingdom, 13th most populous in the United Kingdom. Leicester is at the intersection of two railway lines: the Midland Main Line and the Birmingham to London Stansted Airport line. It is also at the confluence of the M1 motorway, M1/M ...
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American Aging Association
The American Aging Association is a non-profit, tax-exempt biogerontology organization of scientists and laypeople dedicated to biomedical aging studies and geroscience, with the goal of slowing the aging process to extend the healthy human lifespan while preserving and restoring functions typically lost to age-related degeneration. The abbreviation AGE is intended to be representative of the organization, even though it is not an acronym (avoids possible confusion with the American Automobile Association, AAA). History and organization AGE was founded in 1970 by Denham Harman, MD, PhD, who is often known as the "father" of the "free-radical theory of aging". Harman's goal was to form a lay-scientific organization patterned after the American Heart Association to promote biomedical aging research. Harman served as the first president of AGE, and was executive director of AGE for 20 years (1973 to 1993). AGE has received research grants from the National Institutes of Health and ...
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American Society For Neurochemistry
The American Society for Neurochemistry (ASN) is a professional society for neurochemists and neuroscientists from North, Central, and South America and the Caribbean, whose research concerns the role and interactions of small molecules (proteins, peptides, nucleic acids, lipids, sugars) in the development, growth, function, and pathology of the nervous system. History The ASN was incorporated August 5, 1969, and is guided by a set of bylaws and standing rules that incorporate amendments to the bylaws. The first president was Donald B. Tower, Jordi Folch Pi was the second president. The current president (2013–2015) is Etty Benveniste (University of Alabama at Birmingham) and the current president elect is Babette Fuss (Richmond, Virginia). Elections are held ever 2 years to elect the next president, treasurer, secretary, and council members. Organization The officers and council members are assisted by a number of standing committees. An informal history of the ASN has b ...
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H-index
The ''h''-index is an author-level metric that measures both the productivity and citation impact of the publications, initially used for an individual scientist or scholar. The ''h''-index correlates with obvious success indicators such as winning the Nobel Prize, being accepted for research fellowships and holding positions at top universities. The index is based on the set of the scientist's most cited papers and the number of citations that they have received in other publications. The index has more recently been applied to the productivity and impact of a scholarly journal as well as a group of scientists, such as a department or university or country. The index was suggested in 2005 by Jorge E. Hirsch, a physicist at UC San Diego, as a tool for determining theoretical physicists' relative quality and is sometimes called the Hirsch index or Hirsch number. Definition and purpose The ''h''-index is defined as the maximum value of ''h'' such that the given author/journa ...
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Mitochondria
A mitochondrion (; ) is an organelle found in the Cell (biology), cells of most Eukaryotes, such as animals, plants and Fungus, fungi. Mitochondria have a double lipid bilayer, membrane structure and use aerobic respiration to generate adenosine triphosphate (ATP), which is used throughout the cell as a source of chemical energy. They were discovered by Albert von Kölliker in 1857 in the voluntary muscles of insects. The term ''mitochondrion'' was coined by Carl Benda in 1898. The mitochondrion is popularly nicknamed the "powerhouse of the cell", a phrase coined by Philip Siekevitz in a 1957 article of the same name. Some cells in some multicellular organisms lack mitochondria (for example, mature mammalian red blood cells). A large number of unicellular organisms, such as microsporidia, parabasalids and diplomonads, have reduced or transformed their mitochondria into mitosome, other structures. One eukaryote, ''Monocercomonoides'', is known to have completely lost its mitocho ...
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Oxidative Stress
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily Detoxification, detoxify the reactive intermediates or to repair the resulting damage. Disturbances in the normal redox state of cells can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell, including proteins, lipids, and DNA. Oxidative stress from Cellular respiration, oxidative metabolism causes base damage, as well as DNA damage (naturally occurring), strand breaks in DNA. Base damage is mostly indirect and caused by the reactive oxygen species generated, e.g., O2− (superoxide radical), OH (hydroxyl radical) and H2O2 (hydrogen peroxide). Further, some reactive oxidative species act as cellular messengers in redox signaling. Thus, oxidative stress can cause disruptions in normal mechanisms of cellular signaling. In humans, oxidative stress is thought to be involved in the ...
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The American Journal Of Pathology
''The American Journal of Pathology'' is a monthly peer-reviewed medical journal covering pathology. It is published by Elsevier on behalf of the American Society for Investigative Pathology, of which it is an official journal. The editor-in-chief is Martha B. Furie ( Stony Brook University). The journal was established in 1896 as the ''Journal of the Boston Society of Medical Sciences'' and renamed ''The Journal of Medical Research'' in 1901, before obtaining its current title in 1925. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor of 4.307. Editors The following persons have been editors-in-chief An editor-in-chief (EIC), also known as lead editor or chief editor, is a publication's editorial leader who has final responsibility for its operations and policies. The highest-ranking editor of a publication may also be titled editor, managing ... of the journal: References External links * {{DEFAULTSORT:American Journal Of Pathology, ...
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Journal Of Pathology
''The Journal of Pathology'' is a peer-reviewed medical journal that was established in 1892 as ''The Journal of Pathology and Bacteriology'' by German Sims Woodhead. It has been the official journal of the Pathological Society of Great Britain and Ireland (present name: Pathological Society) since its foundation in 1906. The journal has published important papers in pathology and experimental medicine including work by Rudolf Virchow and Ilya Ilyich Mechnikov, both of whom contributed to the inaugural issue. In 1969, the journal's title was shortened to ''The Journal of Pathology''. In January 1999, the first of an ongoing series of Annual Review issues was published, on the topic of "Molecular and Cellular Themes in Cancer Research", edited by Peter A. Hall and David P. Lane. A history of the journal was written in 2006 by former editor-in-chief C. Simon Herrington, as a chapter of a book on the history of the Pathological Society. The journal publishes research papers, reviews, ...
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Journal Of Neurochemistry
The ''Journal of Neurochemistry'' is a biweekly peer-reviewed scientific journal covering all aspects of neurochemistry. It is published by Wiley-Blackwell on behalf of the International Society for Neurochemistry and was established in 1956. The editor-in-chief is Andrew J. Lawrence (University of Melbourne). According to the ''Journal Citation Reports'', the journal has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 5.372. Abstracting and indexing The journal is abstracted and indexed in: Editors-in-chief The following persons have been editor-in-chief of the journal: References External links * {{DEFAULTSORT:Journal Of Neurochemistry Neuroscience journals Wiley-Blackwell academic journals Publications established in 1956 English-language j ...
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Discovery Medicine
''Discovery Medicine'' is an open-access medical journal established in 2001. It is abstracted and indexed in MEDLINE/PubMed. The editor-in-chief is Noel R. Rose (Johns Hopkins University School of Medicine). According to the ''Journal Citation Reports'', the journal has a 2016 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 2.400. References External links * General medical journals English-language journals Open access journals Monthly journals Academic journals established in 2001 {{general-medical-journal-stub ...
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Science Translational Medicine
''Science Translational Medicine'' is an interdisciplinary medical journal established in October 2009 by the American Association for the Advancement of Science. It covers basic, translational, and clinical research on human diseases. According to '' Web of Science'', the journal has a 2021 impact factor of 19.319 Librarian Portal Home
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Journal Of Alzheimer's Disease
The ''Journal of Alzheimer's Disease'' is a peer-reviewed medical journal published by IOS Press covering the etiology, pathogenesis, epidemiology, genetics, treatment, and psychology of Alzheimer's disease. The journal publishes research reports, reviews, short communications, hypotheses, ethics reviews, book reviews, and letters-to-the-editor. The editor-in-chief is George Perry of the University of Texas at San Antonio. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor of 4.472."Journal of Alzheimer's Disease". ''2020 Journal Citation Reports''. Web of Science (Science ed.). Clarivate Analytics. 2020. Alzheimer Award Each year, the Associate Editors of the journal select the best article from the previous year's volume. The awardee is presented the Alzheimer Medal, a 3" bronze medal with the likeness of Alois Alzheimer Alois Alzheimer ( , , ; 14 June 1864 – 19 December 1915) was a German psychiatrist and neuropathologist and a c ...
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