Marco Fraaije
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Marco Fraaije
Marco Wilhelmus Fraaije (born 7 December 1968) is a Dutch scientist whose research concerns enzymology of redox enzymes, enzyme discovery & engineering and biocatalysis at the Groningen Biomolecular Sciences and Biotechnology Institute (GBB) at the University of Groningen. Education Marco Fraaije graduated in 1993 with a Master of Science degree in Molecular Sciences at Wageningen University. Subsequently, he became a doctoral student at Wageningen University under supervision of Willem van Berkel focusing on the mechanism and structure of flavoenzymes and was awarded his PhD in biochemistry in 1998. Following his PhD, he worked as a postdoctoral researcher as EMBO fellow in the protein crystallography research group at the University of Pavia. In 1999, he was made assistant professor at GBB at the University of Groningen, and in 2007 he was appointed as associate professor. In 2012, he was made full professor in molecular enzymology. Research Fraaije is active in the field ...
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University Of Pavia
The University of Pavia ( it, Università degli Studi di Pavia, UNIPV or ''Università di Pavia''; la, Alma Ticinensis Universitas) is a university located in Pavia, Lombardy, Italy. There was evidence of teaching as early as 1361, making it one of the oldest universities in the world. It was the sole university in Milan and the greater Lombardy region until the end of the 19th century. In 2022 the University was recognized by the Times Higher Education among the top 10 in Italy and among the 300 best in the world. Currently, it has 18 departments and 9 faculties. It does not have a main campus; its buildings and facilities are scattered around the city, which is in turn called "a city campus." The university caters to more than 20,000 students who come from Italy and all over the world. The university offers more than 80 undergraduate programs; over 40 master programs, and roughly 20 doctoral programs (including 8 in English). About 1,500 students who enter the university every ...
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Academic Staff Of The University Of Groningen
An academy ( Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of secondary or tertiary higher learning (and generally also research or honorary membership). The name traces back to Plato's school of philosophy, founded approximately 385 BC at Akademia, a sanctuary of Athena, the goddess of wisdom and skill, north of Athens, Greece. Etymology The word comes from the ''Academy'' in ancient Greece, which derives from the Athenian hero, ''Akademos''. Outside the city walls of Athens, the gymnasium was made famous by Plato as a center of learning. The sacred space, dedicated to the goddess of wisdom, Athena, had formerly been an olive grove, hence the expression "the groves of Academe". In these gardens, the philosopher Plato conversed with followers. Plato developed his sessions into a method of teaching philosophy and in 387 BC, established what is known today as the Old Academy. By extension, ''academia'' has come to mean the accumulation, ...
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Wageningen University And Research Alumni
Wageningen () is a municipality and a historic city in the central Netherlands, in the province of Gelderland. It is famous for Wageningen University, which specialises in life sciences. The municipality had a population of in , of which many thousands are students from over 150 countries. Demograpics Inhabitants by nationality 71,68% is Dutch, 28,32% has a migration background. Geography Wageningen is situated on the north bank of the Nederrijn (the Dutch portion of the Lower Rhine) part of the Gelderse valley (Dutch: Gelderse Vallei) and the Veluwe, of which the southwest hill is called the ''Wageningse Berg''. Wageningen can be reached by car from highways A12 via the N781, A15 via the N233 and N225, and A50 via the N225, and from the Ede-Wageningen railway station via a 20-minute bus drive to the Wageningen central terminal (see below)., ''Topographic map of the municipality of Wageningen, July 2013 (click to enlarge)'' History The oldest known settlements in the W ...
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Dutch Biologists
Dutch commonly refers to: * Something of, from, or related to the Netherlands * Dutch people () * Dutch language () Dutch may also refer to: Places * Dutch, West Virginia, a community in the United States * Pennsylvania Dutch Country People Ethnic groups * Germanic peoples, the original meaning of the term ''Dutch'' in English ** Pennsylvania Dutch, a group of early Germanic immigrants to Pennsylvania *Dutch people, the Germanic group native to the Netherlands Specific people * Dutch (nickname), a list of people * Johnny Dutch (born 1989), American hurdler * Dutch Schultz (1902–1935), American mobster born Arthur Simon Flegenheimer * Dutch Mantel, ring name of American retired professional wrestler Wayne Maurice Keown (born 1949) * Dutch Savage, ring name of professional wrestler and promoter Frank Stewart (1935–2013) Arts, entertainment, and media Fictional characters * Dutch (''Black Lagoon''), an African-American character from the Japanese manga and anime ''Black L ...
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21st-century Dutch Scientists
The 1st century was the century spanning AD 1 (Roman numerals, I) through AD 100 (Roman numerals, C) according to the Julian calendar. It is often written as the or to distinguish it from the 1st century BC (or BCE) which preceded it. The 1st century is considered part of the Classical era, epoch, or History by period, historical period. The 1st century also saw the Christianity in the 1st century, appearance of Christianity. During this period, Europe, North Africa and the Near East fell under increasing domination by the Roman Empire, which continued expanding, most notably conquering Britain under the emperor Claudius (AD 43). The reforms introduced by Augustus during his long reign stabilized the empire after the turmoil of the previous century's civil wars. Later in the century the Julio-Claudian dynasty, which had been founded by Augustus, came to an end with the suicide of Nero in AD 68. There followed the famous Year of Four Emperors, a brief period of civil war and inst ...
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Netherlands Organisation For Scientific Research
The Dutch Research Council (NWO, Dutch: Nederlandse Organisatie voor Wetenschappelijk Onderzoek) is the national research council of the Netherlands. NWO funds thousands of top researchers at universities and institutes and steers the course of Dutch science by means of subsidies and research programmes. NWO promotes quality and innovation in science. NWO is an independent administrative body under the auspices of the Dutch Ministry of Education, Culture and Science. NWO directs its approximate budget of 1 billion euros towards Dutch universities and institutes, often on a project basis. Also, NWO has its own research institutes and facilitates international cooperation. Current president of NWO since April 1st, 2021 is Marcel Levi. Former NWO presidents include Stan Gielen, Peter Nijkamp and Jos Engelen. NWO is also known for the annual Spinoza and Stevin Prizes. History The council was established in 1950 as ''Nederlandse Organisatie voor Zuiver-Wetenschappelijk Onderzoek' ...
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Boxtel
Boxtel () is a municipality and a town in the southern Netherlands. The name derives from Buchestelle and is presumably a combination of 'stelle' (Dutch for stable, safe place) and (deer) buck.2019. Etymologiebank.Nl. Accessed April 27 2019 This is the origin of the Van Boxtel family, which has numerous descendants in North Brabant. The town was the site of the Battle of Boxtel fought in September 1794 during the Flanders campaign. It is often principally remembered as the first battle of the future Duke of Wellington. Population centres *Boxtel * Esch * Lennisheuvel *Liempde Topography ''Dutch topographic map of the municipality of Boxtel, 2021'' Notable residents * José van Dijck (born 1960) a new media author and academic * Teun Voeten (born 1961) a Dutch photojournalist and cultural anthropologist * Marcel Wanders (born 1963) a Dutch designer and art director * Dianne van Giersbergen (born 1985 in Liempde) a spinto soprano and singer-songwriter * Sam Feldt (born 1 ...
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Oxidative Enzyme
An oxidative enzyme is an enzyme that catalyses an oxidation reaction. Two most common types of oxidative enzymes are peroxidases, which use hydrogen peroxide, and oxidases, which use molecular oxygen. They increase the rate at which ATP is produced aerobically. Oxidative enzymes are responsible for the browning of fruits like apples. When the surface of apples are exposed to the oxygen in the air, the oxidative enzymes like polyphenol oxidase and catechol oxidase oxidize the fruit (electrons are lost to the air). Such browning can be prevented by cooking the fruit or lowering the pH (which destroys, inactivates, or denatures the enzyme) or by preventing oxygen from getting to the surface (such as by covering the fruit). See also * Oxidoreductase In biochemistry, an oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule, the reductant, also called the electron donor, to another, the oxidant, also called the electron acceptor. This group of en ...
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Protein Engineering
Protein engineering is the process of developing useful or valuable proteins. It is a young discipline, with much research taking place into the understanding of protein folding and recognition for protein design principles. It has been used to improve the function of many enzymes for industrial catalysis. It is also a product and services market, with an estimated value of $168 billion by 2017. There are two general strategies for protein engineering: rational protein design and directed evolution. These methods are not mutually exclusive; researchers will often apply both. In the future, more detailed knowledge of protein structure and function, and advances in high-throughput screening, may greatly expand the abilities of protein engineering. Eventually, even unnatural amino acids may be included, via newer methods, such as expanded genetic code, that allow encoding novel amino acids in genetic code. Approaches Rational design In rational protein design, a scientist uses ...
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Protein Crystallography
X-ray crystallography is the experimental science determining the atomic and molecular structure of a crystal, in which the crystalline structure causes a beam of incident X-rays to diffract into many specific directions. By measuring the angles and intensities of these diffracted beams, a crystallographer can produce a three-dimensional picture of the density of electrons within the crystal. From this electron density, the mean positions of the atoms in the crystal can be determined, as well as their chemical bonds, their crystallographic disorder, and various other information. Since many materials can form crystals—such as salts, metals, minerals, semiconductors, as well as various inorganic, organic, and biological molecules—X-ray crystallography has been fundamental in the development of many scientific fields. In its first decades of use, this method determined the size of atoms, the lengths and types of chemical bonds, and the atomic-scale differences among various mat ...
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