Malaria Control Project
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Malaria Control Project
''malariacontrol.net'' was a volunteer computing project to simulate the transmission dynamics and health effects of malaria. It was part of the Africa@home project. History The malariacontrol.net domain name was first registered on 19 May 2005 under Swiss Tropical Institute. This project was under Africa@home where the latter was conceived and developed by European Organization for Nuclear Research (CERN). ''malariacontrol.net'' was the first to use volunteer computing to model diseases. The model simulates malaria infection in 50,000 to 100,000 people. Each work unit lasted for an hour in average personal computers and the results were returned to University of Geneva for evaluation by researchers. ''malariacontrol.net'' ran all the simulations by using stochastic simulation model. Since 4 November 2010, using the financial support from Bill & Melinda Gates Foundation, Malariacontrol.net developed an open-source software named "Open Malaria" which can be used to simulate outco ...
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Swiss Tropical Institute
The Swiss Tropical and Public Health Institute or Swiss TPH (formerly known as the Swiss Tropical Institute) is an international public health institute working in various disciplines with a particular focus on low- and middle-income countries. It was founded in 1943 through the initiative of Rudolf Geigy. Swiss TPH endeavors to the improve the health of populations internationally and nationally through research, services, education, and training, with a focus on developing countries. In June 2009, the Institute for Social and Preventive Medicine of the University of Basel was integrated into the Swiss Tropical Institute, and in January 2010 the Swiss Tropical Institute changed its name to the Swiss Tropical and Public Health Institute. The Swiss TPH is an associated institute of the University of Basel, and as a public organization it is partially supported by the Swiss Federal Council and the Canton of Basel-Stadt. The greater part of its funding comes from competitively acquir ...
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Sulfadoxine/pyrimethamine
Sulfadoxine/pyrimethamine, sold under the brand name Fansidar, is a combination medication used to treat malaria. It contains sulfadoxine (a sulfonamide) and pyrimethamine (an antiprotozoal). For the treatment of malaria it is typically used along with other antimalarial medication such as artesunate. In areas of Africa with moderate to high rates of malaria, three doses are recommended during the second and third trimester of pregnancy. Side effects include diarrhea, rash, itchiness, headache, and hair loss. Rarely a severe allergic reaction or rash such as toxic epidermal necrolysis, may occur. It is not generally recommended in people with a sulfonamide allergy or significant liver or kidney disease. It works by blocking malaria's ability to use folinic acid. Sulfadoxine/pyrimethamine was initially approved for medical use in the United States in 1981. It is on the World Health Organization's List of Essential Medicines. It is not commercially available in the United States ...
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Free Science Software
Free may refer to: Concept * Freedom, having the ability to do something, without having to obey anyone/anything * Freethought, a position that beliefs should be formed only on the basis of logic, reason, and empiricism * Emancipate, to procure political rights, as for a disenfranchised group * Free will, control exercised by rational agents over their actions and decisions * Free of charge, also known as gratis. See Gratis vs libre. Computing * Free (programming), a function that releases dynamically allocated memory for reuse * Free format, a file format which can be used without restrictions * Free software, software usable and distributable with few restrictions and no payment * Freeware, a broader class of software available at no cost Mathematics * Free object ** Free abelian group ** Free algebra ** Free group ** Free module ** Free semigroup * Free variable People * Free (surname) * Free (rapper) (born 1968), or Free Marie, American rapper and media pers ...
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Science In Society
''Science In Society: An Introduction to Social Studies of Science'' () is a 2004 book by Massimiano Bucchi. The book explains how science works, what sociologists find to be of interest, and how scientific knowledge is produced. There are chapters on the relevance of science to contemporary life, Kuhn's work and its modern relevance, as well as the role of scientific communication.{{cite journal , url=http://www.sociology.org/content/2005/tier1/morrell_review.pdf , title=Book Review - Science in Society: an Introduction to Social Studies of Science , author=Morrell, Peter , journal=Electronic Journal of Sociology , year=2005 , issn=1198-3655 See also *List of books about the politics of science This is a list of notable books about the politics of science that have their own articles on Wikipedia. Environment * ''Merchants of Doubt, Merchants of Doubt: How a Handful of Scientists Obscured the Truth on Issues from Tobacco Smoke to Global ... References 2004 non-fiction ...
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First Monday (journal)
''First Monday'' is a monthly peer-reviewed open access academic journal covering research on the Internet. Publication The journal is sponsored and hosted by the University of Illinois at Chicago. It is published on the first Monday of every month. In 2011, the journal had an acceptance rate of about 15%. The journal has no article processing charges and no advertisements. History According to the chief editor, Edward Valauskas, the journal emerged before the open access model emerged: “We didn’t call it open access in 1995 but we were certainly a precursor to the whole notion of open access. We felt very strongly that the journal should have all its content made freely available and we insisted with he Danish publisherMunksgaard that the scholars who contributed would retain copyright of their work that they published in the journal. We felt it would encourage scholars to contribute and then re-use their content in lots of different ways". ''First Monday'' is among the fi ...
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Piperonyl Butoxide
Piperonyl butoxide (PBO) is a pale yellow to light brown liquidNational Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina. organic compound used as a synergist component of pesticide formulations. That is, despite having no pesticidal activity of its own, it enhances the potency of certain pesticides such as carbamates, pyrethrins, pyrethroids, and rotenone. It is a semisynthetic derivative of safrole.Robert L. Metcalf "Insect Control" in Ullmann’s Encyclopedia of Industrial Chemistry" Wiley-VCH, Weinheim, 2002. History PBO was developed in the late 1930s and early 1940s to enhance the performance of the naturally derived insecticide pyrethrum. Pyrethrum is and was an important insecticide against mosquitoes and other disease-carrying vectors, thereby providing public health benefits, e.g., preventing malaria. Although exhibi ...
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Pyrethroid
A pyrethroid is an organic compound similar to the natural pyrethrins, which are produced by the flowers of pyrethrums (''Chrysanthemum cinerariaefolium'' and ''Chrysanthemum coccineum, C. coccineum''). Pyrethroids are used as commercial and household insecticides. In household concentrations pyrethroids are generally harmless to humans. However, pyrethroids are toxic to insects such as bees, dragonflies, mayflies, Horse-fly, gadflies, and some other invertebrates, including those that constitute the base of aquatic and terrestrial food webs. Pyrethroids are toxic to aquatic organisms, especially fish.Pyrethroids fact sheet
from the Illinois Department of Public Health.
They have been shown to be an effective control measure for malaria outbreaks, through indoor applications.


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World Health Organization
The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of health". Headquartered in Geneva, Switzerland, it has six regional offices and 150 field offices worldwide. The WHO was established on 7 April 1948. The first meeting of the World Health Assembly (WHA), the agency's governing body, took place on 24 July of that year. The WHO incorporated the assets, personnel, and duties of the League of Nations' Health Organization and the , including the International Classification of Diseases (ICD). Its work began in earnest in 1951 after a significant infusion of financial and technical resources. The WHO's mandate seeks and includes: working worldwide to promote health, keeping the world safe, and serve the vulnerable. It advocates that a billion more people should have: universal health care coverag ...
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RTS,S
RTS,S/AS01 (trade name Mosquirix) is a recombinant protein-based malaria vaccine. In October 2021, the vaccine was endorsed by the World Health Organization (WHO) for "broad use" in children, making it the first malaria vaccine candidate, and first vaccine to address parasitic infection, to receive this recommendation. The RTS,S vaccine was conceived of and created in the late 1980s by scientists working at SmithKline Beecham Biologicals (now GlaxoSmithKline (GSK) Vaccines) laboratories in Belgium. The vaccine was further developed through a collaboration between GSK and the Walter Reed Army Institute of Research in the U.S. state of Maryland and has been funded in part by the PATH Malaria Vaccine Initiative and the Bill and Melinda Gates Foundation. Its efficacy ranges from 26 to 50% in infants and young children. In July 2015, the vaccine received a positive scientific opinion by the European Medicines Agency (EMA) for use outside the European Union , it is the world's first ...
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Plasmodium Falciparum
''Plasmodium falciparum'' is a Unicellular organism, unicellular protozoan parasite of humans, and the deadliest species of ''Plasmodium'' that causes malaria in humans. The parasite is transmitted through the bite of a female ''Anopheles'' mosquito and causes the disease's most dangerous form, falciparum malaria. It is responsible for around 50% of all malaria cases. ''P. falciparum'' is therefore regarded as the deadliest parasite in humans. It is also associated with the development of blood cancer (Burkitt's lymphoma) and is classified as a List of IARC Group 2A carcinogens, Group 2A (probable) carcinogen. The species originated from the malarial parasite ''Laverania'' found in gorillas, around 10,000 years ago. Alphonse Laveran was the first to identify the parasite in 1880, and named it ''Oscillaria malariae''. Ronald Ross discovered its transmission by mosquito in 1897. Giovanni Battista Grassi elucidated the complete transmission from a female Anopheles, anopheline mosquit ...
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Malaria Vaccine
A malaria vaccine is a vaccine that is used to prevent malaria. The only approved use of a vaccine outside the EU, as of 2022, is RTS,S, known by the brand name ''Mosquirix''. In October 2021, the WHO for the first time recommended the large-scale use of a malaria vaccine for children living in areas with moderate-to-high malaria transmission. Four injections are required for full protection. Research continues with other malaria vaccines. The most effective malaria vaccine is R21/Matrix-M, with a 77% efficacy rate shown in initial trials and significantly higher antibody levels than with the RTS,S vaccine. It is the first vaccine that meets the World Health Organization's (WHO) goal of a malaria vaccine with at least 75% efficacy. Approved vaccines RTS,S RTS,S, developed by PATH Malaria Vaccine Initiative (MVI) and GlaxoSmithKline (GSK) with support from the Bill and Melinda Gates Foundation, is the most recently developed recombinant vaccine. It consists of the ''P. falci ...
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Cross-platform
In computing, cross-platform software (also called multi-platform software, platform-agnostic software, or platform-independent software) is computer software that is designed to work in several computing platforms. Some cross-platform software requires a separate build for each platform, but some can be directly run on any platform without special preparation, being written in an interpreted language or compiled to portable bytecode for which the interpreters or run-time packages are common or standard components of all supported platforms. For example, a cross-platform application may run on Microsoft Windows, Linux, and macOS. Cross-platform software may run on many platforms, or as few as two. Some frameworks for cross-platform development are Codename One, Kivy, Qt, Flutter, NativeScript, Xamarin, Phonegap, Ionic, and React Native. Platforms ''Platform'' can refer to the type of processor (CPU) or other hardware on which an operating system (OS) or application runs, t ...
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