Maiztegui National Human Viral Disease Institute
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Maiztegui National Human Viral Disease Institute
The Maiztegui National Human Viral Disease Institute is a viral research laboratory in Pergamino, Argentina. Overview The Maiztegui National Human Viral Disease Institute originated in the Clinical Research and Medical Education Center in Pergamino. The city, a prosperous agricultural hub in the heart of Argentina's corn belt, was also the epicenter in 1958 of a sudden outbreak of Argentine hemorrhagic fever, a condition known among the country's rural population as ''the mal de los rastrojos'' ("the sickness of the corn straw"). Transmitted mainly by mice dwelling in fallow corn fields, the disease was believed to affect up to 1,000 people annually and claimed up to a 30% mortality rate in its early years.ANLIS
One of its researchers, Dr.

Pergamino
Pergamino () is an Argentine city in the Buenos Aires Province, Province of Buenos Aires. It has a population of about 104,985 inhabitants as per the and is the administrative seat of its county, Pergamino Partido. Its UN/LOCODE is ARPGO. History Long valued for its many springs and fertile land, the area had been home to the Charrúa and Mapuche, Araucanian people when it was first noticed by Spain, Spanish colonist around 1620. Becoming a posada along the trade route between colonial Buenos Aires and Cordoba, Argentina, Córdoba, the settlement was given its name on 3 January 1626, for the parchment paper (document lost by a group of Spaniards) found there and conforming to an Araucanian term meaning "red soil." The settlement's first businesses were established in 1700 and in 1749, recurrent attacks by displaced natives led to the construction of a fort. These attacks did not cease, however, and on 8 August 1751 the settlement was destroyed. The site continued to be of interest ...
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Argentina
Argentina (), officially the Argentine Republic ( es, link=no, República Argentina), is a country in the southern half of South America. Argentina covers an area of , making it the second-largest country in South America after Brazil, the fourth-largest country in the Americas, and the eighth-largest country in the world. It shares the bulk of the Southern Cone with Chile to the west, and is also bordered by Bolivia and Paraguay to the north, Brazil to the northeast, Uruguay and the South Atlantic Ocean to the east, and the Drake Passage to the south. Argentina is a federal state subdivided into twenty-three provinces, and one autonomous city, which is the federal capital and largest city of the nation, Buenos Aires. The provinces and the capital have their own constitutions, but exist under a federal system. Argentina claims sovereignty over the Falkland Islands, South Georgia and the South Sandwich Islands, and a part of Antarctica. The earliest recorded human prese ...
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Argentine Agriculture
Agriculture is one of the bases of Argentina's economy. Argentine agriculture is relatively capital intensive, today providing about 7% of all employment,Ministerio de Economía y Producción – República Argentina
and, even during its period of dominance around 1900, accounting for no more than a third of all labor.Rock, David. ''Argentina: 1516–1982.'' University of California Press, 1987. Having accounted for nearly 20% of GDP as late as 1959, it adds, directly, less than 10% today. Agricultural goods, whether raw or processed earn over half of Argentina's foreign exchange and arguably remain an indispensable pillar of the country's social progress and economic prosperity. An estimated 10-15% of Argentine farmland is foreign owned. One fourth of ...
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Argentine Hemorrhagic Fever
Argentine hemorrhagic fever (AHF) or O'Higgins disease, also known in Argentina as ''mal de los rastrojos'' (stubble disease) is a hemorrhagic fever and zoonotic infectious disease occurring in Argentina. It is caused by the '' Junín virus'' (an arenavirus, closely related to the ''Machupo virus'', causative agent of Bolivian hemorrhagic fever). Its vector is the drylands vesper mouse, a rodent found in Argentina and Paraguay. Epidemiology The disease was first reported in the town of in Buenos Aires province, Argentina in 1958, giving it one of the names by which it is known. Various theories about its nature were proposed: it was Weil's disease, leptospirosis, caused by chemical pollution. It was associated with fields containing stubble after the harvest, giving it another of its names. The endemic area of AHF covers approximately 150,000 km2, compromising the provinces of Buenos Aires, Córdoba, Santa Fe and La Pampa, with an estimated risk population of 5 million. ...
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Julio Isidro Maiztegui
Julio Isidro Maiztegui (August 25, 1931 – August 29, 1993) was an Argentine physician and epidemiologist. Life and work Maiztegui was born in Bahía Blanca, Argentina, in 1931. He received a medical degree from the University of Buenos Aires, in 1957, and the following year, began his residency at the Boston University Hospital. He specialized in the treatment of infectious disease and in 1964, received a master's degree in Public Health at Harvard. He entered the Clinical Research and Medical Education Center (CEMIC) in Buenos Aires (Argentina) in 1965 and went on to receive a Master of Epidemiology from the University of London, in 1969.Dr. Julio Maiztegui Foundation
Returning to Argentina, he began research on

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Blood Plasma
Blood plasma is a light amber-colored liquid component of blood in which blood cells are absent, but contains proteins and other constituents of whole blood in suspension. It makes up about 55% of the body's total blood volume. It is the intravascular part of extracellular fluid (all body fluid outside cells). It is mostly water (up to 95% by volume), and contains important dissolved proteins (6–8%; e.g., serum albumins, globulins, and fibrinogen), glucose, clotting factors, electrolytes (, , , , , etc.), hormones, carbon dioxide (plasma being the main medium for excretory product transportation), and oxygen. It plays a vital role in an intravascular osmotic effect that keeps electrolyte concentration balanced and protects the body from infection and other blood-related disorders. Blood plasma is separated from the blood by spinning a vessel of fresh blood containing an anticoagulant in a centrifuge until the blood cells fall to the bottom of the tube. The blood plasma is t ...
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Saline (medicine)
Saline (also known as saline solution) is a mixture of sodium chloride (salt) and water. It has a number of uses in medicine including cleaning wounds, removal and storage of contact lenses, and help with dry eyes. By injection into a vein it is used to treat dehydration such as that from gastroenteritis and diabetic ketoacidosis. Large amounts may result in fluid overload, swelling, acidosis, and high blood sodium. In those with long-standing low blood sodium, excessive use may result in osmotic demyelination syndrome. Saline is in the crystalloid family of medications. It is most commonly used as a sterile 9 g of salt per litre (0.9%) solution, known as normal saline. Higher and lower concentrations may also occasionally be used. Saline is acidic, with a pH of 5.5 (due mainly to dissolved carbon dioxide). The medical use of saline began around 1831. It is on the World Health Organization's List of Essential Medicines. In 2020, sodium was the 274th most commonly p ...
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World Health Organization
The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of health". Headquartered in Geneva, Switzerland, it has six regional offices and 150 field offices worldwide. The WHO was established on 7 April 1948. The first meeting of the World Health Assembly (WHA), the agency's governing body, took place on 24 July of that year. The WHO incorporated the assets, personnel, and duties of the League of Nations' Health Organization and the , including the International Classification of Diseases (ICD). Its work began in earnest in 1951 after a significant infusion of financial and technical resources. The WHO's mandate seeks and includes: working worldwide to promote health, keeping the world safe, and serve the vulnerable. It advocates that a billion more people should have: universal health care coverag ...
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Arenavirus
An arenavirus is a bisegmented ambisense RNA virus that is a member of the family ''Arenaviridae''. These viruses infect rodents and occasionally humans. A class of novel, highly divergent arenaviruses, properly known as reptarenaviruses, have also been discovered which infect snakes to produce inclusion body disease. At least eight arenaviruses are known to cause human disease. The diseases derived from arenaviruses range in severity. Aseptic meningitis, a severe human disease that causes inflammation covering the brain and spinal cord, can arise from the lymphocytic choriomeningitis virus. Hemorrhagic fever syndromes, including Lassa fever, are derived from infections such as Guanarito virus, Junin virus, Lassa virus, Lujo virus, Machupo virus, Sabia virus, or Whitewater Arroyo virus. Because of the epidemiological association with rodents, some arenaviruses and bunyaviruses are designated as roboviruses. Structure Viewed in cross-section, arenaviruses contain grainy parti ...
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Arbovirus
Arbovirus is an informal name for any virus that is transmitted by arthropod vectors. The term ''arbovirus'' is a portmanteau word (''ar''thropod-''bo''rne ''virus''). ''Tibovirus'' (''ti''ck-''bo''rne ''virus'') is sometimes used to more specifically describe viruses transmitted by ticks, a superorder within the arthropods. Arboviruses can affect both animals (including humans) and plants. In humans, symptoms of arbovirus infection generally occur 3–15 days after exposure to the virus and last three or four days. The most common clinical features of infection are fever, headache, and malaise, but encephalitis and viral hemorrhagic fever may also occur. Signs and symptoms The incubation period – the time between when infection occurs and when symptoms appear – varies from virus to virus, but is usually limited between 2 and 15 days for arboviruses. The majority of infections, however, are asymptomatic. Among cases in which symptoms do appear, symptoms tend to be non-s ...
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Hantavirus
''Orthohantavirus'' is a genus of single-stranded, enveloped, negative-sense RNA viruses in the family ''Hantaviridae'' within the order ''Bunyavirales''. Members of this genus may be called orthohantaviruses or simply hantaviruses. Orthohantaviruses typically cause chronic asymptomatic infection in rodents. Humans may become infected with hantaviruses through contact with rodent urine, saliva, or feces. Some strains cause potentially fatal diseases in humans, such as hantavirus hemorrhagic fever with renal syndrome (HFRS), or hantavirus pulmonary syndrome (HPS), also known as hantavirus cardiopulmonary syndrome (HCPS), while others have not been associated with known human disease (e.g. Prospect Hill virus). HPS (HCPS) is a "rare respiratory illness associated with the inhalation of aerosolized rodent excreta (urine and feces) contaminated by hantavirus particles." Human infections of hantaviruses have almost entirely been linked to human contact with rodent excrement; however, ...
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1978 Establishments In Argentina
Events January * January 1 – Air India Flight 855, a Boeing 747 passenger jet, crashes off the coast of Bombay, killing 213. * January 5 – Bülent Ecevit, of Republican People's Party, CHP, forms the new government of Turkey (42nd government). * January 6 – The Holy Crown of Hungary (also known as Stephen of Hungary Crown) is returned to Hungary from the United States, where it was held since World War II. * January 10 – Pedro Joaquín Chamorro Cardenal, a critic of the Nicaraguan government, is assassinated; riots erupt against Anastasio Somoza Debayle, Somoza's government. * January 18 – The European Court of Human Rights finds the British government guilty of mistreating prisoners in Northern Ireland, but not guilty of torture. * January 22 – Ethiopia declares the ambassador of West Germany ''persona non grata''. * January 24 ** Soviet Union, Soviet satellite Kosmos 954 burns up in Earth's atmosphere, scattering debris over Canada's Northwest Territories. ** ...
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