Macklin's Syndrome
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Macklin's Syndrome
Hamman's syndrome, also known as Macklin's syndrome, is a syndrome of spontaneous subcutaneous emphysema (air in the subcutaneous tissues of the skin) and pneumomediastinum (air in the mediastinum, the center of the chest cavity), sometimes associated with pain and, less commonly, dyspnea (difficulty breathing), dysphonia, and a low-grade fever. Hamman's syndrome can cause Hamman's sign, an unusual combination of sounds that can be heard with a stethoscope. Causes The cause of Hamman's syndrome is most commonly unknown (idiopathic). Excessive duration and/or intensity of activities that mimic valsalva manoeuvres, ''i.e.'' that increase intrathoracic pressure, can cause barotrauma, and hence pregnancy (and constipation and other causes of excessive straining) can be a precipitating cause of Hamman's syndrome. Indeed, it is estimated to occur in approximately 1 in 100,000 live births and is associated with prolonged labour times. Additionally, vomiting and coughing have also been ...
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Mediastinum
The mediastinum (from ) is the central compartment of the thoracic cavity. Surrounded by loose connective tissue, it is an undelineated region that contains a group of structures within the thorax, namely the heart and its vessels, the esophagus, the trachea, the phrenic nerve, phrenic and cardiac nerves, the thoracic duct, the thymus and the lymph nodes of the central chest. Anatomy The mediastinum lies within the thorax and is enclosed on the right and left by pulmonary pleurae, pleurae. It is surrounded by the chest wall in front, the lungs to the sides and the Spine (anatomy), spine at the back. It extends from the sternum in front to the vertebral column behind. It contains all the organs of the thorax except the lungs. It is continuous with the loose connective tissue of the neck. The mediastinum can be divided into an upper (or superior) and lower (or inferior) part: * The superior mediastinum starts at the superior thoracic aperture and ends at the #Thoracic plane, t ...
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