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Hyperthermia: Characterized on the left. Normal body temperature (thermoregulatory set point) is shown in green, while the hyperthermic temperature is shown in red. As can be seen, hyperthermia can be conceptualized as an increase above the thermoregulatory set point.
Hypothermia: Characterized in the center: Normal body temperature is shown in green, while the hypothermic temperature is shown in blue. As can be seen, hypothermia can be conceptualized as a decrease below the thermoregulatory set point.
Fever: Characterized on the right: Normal body temperature is shown in green. It reads "New Normal" because the thermoregulatory set point has risen. This has caused what was the normal body temperature (in blue) to be considered hypothermic.

Scholars viewing fever from an organismal and evolutionary perspective note the value to an organism of having a fever response, in particular in response to infective disease.[16][48][49] On the other hand, while fever evolved as a defense mechanism, treating fever does not appear to worsen outcomes.[16]In addition, fever can result from a reaction to an incompatible blood product.[46]

Teething is not a cause of fever.[47]

Scholars viewing fever from an organismal and evolutionary perspective note the value to an organism of having a fever response, in particular in response to infective disease.[16][48][49] On the other hand, while fever evolved as a defense mechanism, treating fever does not appear to worsen outcomes.[16][17] Studies using warm-blooded vertebrates suggest that they recover more rapidly from infections or critical illness due to fever.[50] Other studies suggest reduced mortality in bacterial infections when fever was present.[51] Fever is thought to contribute to host defense,[16] as the reproduction of pathogens with strict temperature requirements can be hindered, and the rates of some important immunological reactions[clarification needed] are increased by temperature.[52] Fever has been described in teaching texts as assisting the healing process in various ways, including:

Pathophysiology


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