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MZF1
Myeloid zinc finger 1 is a protein that in humans is encoded by the ''MZF1'' gene. Interactions MZF1 has been shown to interact with SCAND1. In 2014, the laboratory of Nathan H. Lents showed that MZF-1 induces the GAPDH Glyceraldehyde 3-phosphate dehydrogenase (abbreviated GAPDH) () is an enzyme of about 37kDa that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules. In addition to this long establishe ... gene, something that must be considered when GAPDH is used as a loading control in experiments that may induce or perturb MZF-1. The same group later showed that MZF-1 induces CTGF and NOV, two members of the CCN gene family. References Further reading * * * * * * * * * * {{gene-19-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SCAND1
SCAN domain-containing protein 1 is a protein that in humans is encoded by the ''SCAND1'' gene. Function The SCAN domain is a highly conserved, leucine-rich motif of approximately 60 amino acids originally found within a subfamily of zinc finger proteins. This gene belongs to a family of genes that encode an isolated SCAN domain, but no zinc finger motif. Functional studies have established that the SCAN box is a protein interaction domain that mediates both hetero- and homoprotein associations, and maybe involved in regulation of transcriptional activity. Two transcript variants with different 5' UTRs, but encoding the same protein, have been described for this gene. Interactions SCAND1 has been shown to interact with MZF1 Myeloid zinc finger 1 is a protein that in humans is encoded by the ''MZF1'' gene. Interactions MZF1 has been shown to interact with SCAND1. In 2014, the laboratory of Nathan H. Lents showed that MZF-1 induces the GAPDH Glyceraldehyde .... ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nathan H
Nathan or Natan may refer to: People *Nathan (given name), including a list of people and characters with this name *Nathan (surname) *Nathan (prophet), a person in the Hebrew Bible *Nathan (son of David), biblical figure, son of King David and Bathsheba *Nathan of Gaza, a charismatic figure who spread the word of Eli the Prophet *Starboy Nathan, a British singer who used the stage name "Nathan" from 2006 to 2011 * Nathan (footballer, born 1994), full name ''Nathan Athaydes Campos Ferreira'', Brazilian winger * Nathan (footballer, born 1995), full name ''Nathan Raphael Pelae Cardoso'', Brazilian centre back *Nathan (footballer, born 1996), full name ''Nathan Allan de Souza'', Brazilian midfielder *Nathan (footballer, born May 1999), full name ''Nathan Crepaldi da Cruz'', Brazilian forward *Nathan (footballer, born August 1999), full name ''Nathan Palafoz de Sousa'', Brazilian forward Other uses *Nathan, Queensland, a suburb of Brisbane in Australia *Nathan (band), an alt-coun ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
