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MDSC Stadium Manjeri
MDSC may refer to: * Mediterranean–Dead Sea Canal * Myeloid-derived suppressor cell Myeloid-derived suppressor cells (MDSC) are a heterogeneous group of immune cells from the myeloid lineage (a family of cells that originate from bone marrow stem cells). MDSCs expand under pathologic conditions such as chronic infection and canc ..., immunosuppressive cells from the myeloid lineage * MDSc, a dental degree * Mount Diablo Silverado Council {{disamb ...
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Mediterranean–Dead Sea Canal
The Mediterranean–Dead Sea Canal (MDSC) is a proposed project to dig a canal from the Mediterranean Sea to the Dead Sea, taking advantage of the 400-metre difference in water level between the seas. The project could correct the drop in the level of the Dead Sea observed in recent years. The canal could also be used to generate hydroelectric power because of surface difference and maybe by salinity gradient power, and desalinate water by reverse osmosis. History The idea was first proposed by William Allen in 1855 in a work called "The Dead Sea – A new route to India". At that time it was not yet known that the Dead Sea lies below sea level, and Allen proposed this canal as an alternative to the Suez Canal. Later, many engineers and politicians picked up on the idea, including Theodor Herzl in his 1902 novel ''Altneuland''. Most of the early proposals used the East bank of the Jordan River, but a modified form, using the West bank, was proposed after the separation of Tran ...
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Myeloid-derived Suppressor Cell
Myeloid-derived suppressor cells (MDSC) are a heterogeneous group of immune cells from the myeloid lineage (a family of cells that originate from bone marrow stem cells). MDSCs expand under pathologic conditions such as chronic infection and cancer, as a result of altered haematopoiesis. MDSCs differ from other myeloid cell types in that they have immunosuppressive activities, as opposed to immune-stimulatory properties. Similar to other myeloid cells, MDSCs interact with immune cell types such as T cells, dendritic cells, macrophages and natural killer cells to regulate their functions. Tumors with high levels of infiltration by MDSCs have been associated with poor patient outcome and resistance to therapies. MDSCs can also be detected in the blood. In patients with breast cancer, levels of MDSC in blood are about 10-fold higher than normal. The size of the myeloid suppressor compartment is considered to be an important factor in the success or failure of cancer immunotherapy, h ...
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