Lymphocystivirus
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Lymphocystivirus
''Lymphocystivirus'' is a genus of viruses, in the family ''Iridoviridae''. Fish serve as natural hosts. There are four species in this genus. Diseases associated with this genus include: tumor-like growths on the skin. Hosts ''Lymphocystivirus'' is one of six genera of viruses within the viral family ''Iridoviridae'', and one of three genera within this family which infect teleost fishes, along with ''Megalocytivirus'' and ''Ranavirus''. Lymphocystiviruses infect more than 140 freshwater and marine species, spanning at least 42 host families worldwide, causing the chronic, self-limiting clinical disease, lymphocystis. While lymphocystis does not cause mass mortality events like megalocytiviruses and ranaviruses, fish with lymphocystis exhibit grossly visible papilloma-like skin lesions which substantially reduce their commercial value. No vaccines are currently available for lymphocystis viruses. Taxonomy The genus contains the following species: * ''Lymphocystis disease virus ...
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Lymphocystis Disease Virus 1
''Lymphocystivirus'' is a genus of viruses, in the family ''Iridoviridae''. Fish serve as natural hosts. There are four species in this genus. Diseases associated with this genus include: tumor-like growths on the skin. Hosts ''Lymphocystivirus'' is one of six genera of viruses within the viral family ''Iridoviridae'', and one of three genera within this family which infect teleost fishes, along with ''Megalocytivirus'' and ''Ranavirus''. Lymphocystiviruses infect more than 140 freshwater and marine species, spanning at least 42 host families worldwide, causing the chronic, self-limiting clinical disease, lymphocystis. While lymphocystis does not cause mass mortality events like megalocytiviruses and ranaviruses, fish with lymphocystis exhibit grossly visible papilloma-like skin lesions which substantially reduce their commercial value. No vaccines are currently available for lymphocystis viruses. Taxonomy The genus contains the following species: * ''Lymphocystis disease virus ...
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Iridoviridae
''Iridoviridae'' is a family of viruses with double-stranded DNA genomes. Amphibians, fish, and invertebrates such as arthropods serve as natural hosts. There are currently 22 species in this family, divided among two subfamilies and seven genera. Nomenclature The name is derived from Iris, the Greek goddess of the rainbow. This name was chosen because of the "rainbow-like" iridescence observed in heavily infected insects and pelleted samples of invertebrate iridoviruses. It may refer to any member of the ''Iridoviridae'' family or a particular genus within ''Iridoviridae''. Taxonomy The following subfamilies and genera are recognized (-''virinae'' denotes subfamily and -''virus'' denotes genus): * '' Alphairdovirinae'' ** ''Lymphocystivirus'' ** ''Megalocytivirus'' ** ''Ranavirus'' * ''Betairidovirinae'' ** ''Chloriridovirus'' ** '' Daphniairidovirus'' ** '' Decapodiridovirus'' ** ''Iridovirus'' Structure The virions are icosahedral with triangulation number (T) = 189–217, ...
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Megalocytivirus
''Megalocytivirus'' is a genus of viruses in the family ''Iridoviridae'' and one of three genera within this family which infect teleost fishes, along with ''Lymphocystivirus'' and ''Ranavirus''. Megalocytiviruses are an emerging group of closely related dsDNA viruses which cause systemic infections in a wide variety of wild and cultured fresh and saltwater fishes. Megalocytivirus outbreaks are of considerable economic importance in aquaculture, as epizootics can result in moderate fish loss or mass mortality events of cultured fishes.Yanong RPE, Waltzek TB (2010). "Megalocytivirus infections in fish, with emphasis on ornamental species." University of Florida Institute of Food and Agricultural Sciences Extension FA182 1-7. http://edis.ifas.ufl.edu/fa182 http://edis.ifas.ufl.edu/pdffiles/FA/FA18200.pdf Taxonomy The family ''Iridoviridae'' is divided into seven genera, including ''Chloriridovirus'', ''Iridovirus'', ''Lymphocystivirus'', ''Megalocytivirus'', '' Daphniairidovir ...
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Ranavirus
''Ranavirus'' is a genus of viruses, in the family ''Iridoviridae''. There are six other genus, genera of viruses within the family ''Iridoviridae'', but ''Ranavirus'' is the only one that includes viruses that are infectious to amphibians and reptiles. Additionally, it is one of the three genera within this family which infect teleostei, teleost fishes, along with ''Lymphocystivirus'' and ''Megalocytivirus''. Ecological impact The Ranaviruses, like the Megalocytiviruses, are an emerging infectious disease, emerging group of closely related DNA, dsDNA viruses which cause systemic disease, systemic infections in a wide variety of wild and cultured fresh and saltwater fishes. As with Megalocytiviruses, ''Ranavirus'' outbreaks are therefore of considerable economic importance in aquaculture, as epizootics can result in moderate fish loss or mass mortality events of cultured fishes. Unlike Megalocytiviruses, however, ''Ranavirus'' infections in amphibians have been implicated as a ...
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Lymphocystis
Lymphocystis is a common viral disease of freshwater and saltwater fish. The virus that causes this disease belongs to the genus ''Lymphocystivirus'' of the family Iridoviridae. Aquarists often come across this virus when their fish are stressed such as when put into a new environment and the virus is able to grow. The fish start growing small white pin-prick like growths on their fins or skin and this is often mistaken for infection by ''Ichthyophthirius multifiliis'' in the early stages. It soon clumps together to form a cauliflower-like growth on the skin, mouth, fins, and occasionally the gills. This virus appears to present itself as lesions at differing locations depending on the species of fish being attacked, often complicating initial diagnosis. Lesions at the base of the dorsal fin are common among freshwater species of Central American origin, most notably ''Herichthys carpintis''; inside the mouth of ''Herichthys cyanoguttatus'' and ''Geophagus steindachneri''; on t ...
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Lymphocystis Disease Virus 2
Lymphocystis is a common viral disease of freshwater and saltwater fish. The virus that causes this disease belongs to the genus ''Lymphocystivirus'' of the family Iridoviridae. Aquarists often come across this virus when their fish are stressed such as when put into a new environment and the virus is able to grow. The fish start growing small white pin-prick like growths on their fins or skin and this is often mistaken for infection by ''Ichthyophthirius multifiliis'' in the early stages. It soon clumps together to form a cauliflower-like growth on the skin, mouth, fins, and occasionally the gills. This virus appears to present itself as lesions at differing locations depending on the species of fish being attacked, often complicating initial diagnosis. Lesions at the base of the dorsal fin are common among freshwater species of Central American origin, most notably ''Herichthys carpintis''; inside the mouth of ''Herichthys cyanoguttatus'' and ''Geophagus steindachneri''; on t ...
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Lymphocystis Disease Virus 4
Lymphocystis is a common viral disease of freshwater and saltwater fish. The virus that causes this disease belongs to the genus ''Lymphocystivirus'' of the family Iridoviridae. Aquarists often come across this virus when their fish are stressed such as when put into a new environment and the virus is able to grow. The fish start growing small white pin-prick like growths on their fins or skin and this is often mistaken for infection by ''Ichthyophthirius multifiliis'' in the early stages. It soon clumps together to form a cauliflower-like growth on the skin, mouth, fins, and occasionally the gills. This virus appears to present itself as lesions at differing locations depending on the species of fish being attacked, often complicating initial diagnosis. Lesions at the base of the dorsal fin are common among freshwater species of Central American origin, most notably ''Herichthys carpintis''; inside the mouth of ''Herichthys cyanoguttatus'' and ''Geophagus steindachneri''; on t ...
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Lymphocystis Disease Virus 3
Lymphocystis is a common viral disease of freshwater and saltwater fish. The virus that causes this disease belongs to the genus ''Lymphocystivirus'' of the family Iridoviridae. Aquarists often come across this virus when their fish are stressed such as when put into a new environment and the virus is able to grow. The fish start growing small white pin-prick like growths on their fins or skin and this is often mistaken for infection by ''Ichthyophthirius multifiliis'' in the early stages. It soon clumps together to form a cauliflower-like growth on the skin, mouth, fins, and occasionally the gills. This virus appears to present itself as lesions at differing locations depending on the species of fish being attacked, often complicating initial diagnosis. Lesions at the base of the dorsal fin are common among freshwater species of Central American origin, most notably ''Herichthys carpintis''; inside the mouth of ''Herichthys cyanoguttatus'' and ''Geophagus steindachneri''; on t ...
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Receptor-mediated Endocytosis
Receptor-mediated endocytosis (RME), also called clathrin-mediated endocytosis, is a process by which cells absorb metabolites, hormones, proteins – and in some cases viruses – by the inward budding of the plasma membrane (invagination). This process forms vesicles containing the absorbed substances and is strictly mediated by receptors on the surface of the cell. Only the receptor-specific substances can enter the cell through this process. Process Although receptors and their ligands can be brought into the cell through a few mechanisms (e.g. caveolin and lipid raft), clathrin-mediated endocytosis remains the best studied. Clathrin-mediated endocytosis of many receptor types begins with the ligands binding to receptors on the cell plasma membrane. The ligand and receptor will then recruit adaptor proteins and clathrin triskelions to the plasma membrane around where invagination will take place. Invagination of the plasma membrane then occurs, forming a clathrin-coated pit. ...
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Cell Nucleus
The cell nucleus (pl. nuclei; from Latin or , meaning ''kernel'' or ''seed'') is a membrane-bound organelle found in eukaryotic cells. Eukaryotic cells usually have a single nucleus, but a few cell types, such as mammalian red blood cells, have no nuclei, and a few others including osteoclasts have many. The main structures making up the nucleus are the nuclear envelope, a double membrane that encloses the entire organelle and isolates its contents from the cellular cytoplasm; and the nuclear matrix, a network within the nucleus that adds mechanical support. The cell nucleus contains nearly all of the cell's genome. Nuclear DNA is often organized into multiple chromosomes – long stands of DNA dotted with various proteins, such as histones, that protect and organize the DNA. The genes within these chromosomes are structured in such a way to promote cell function. The nucleus maintains the integrity of genes and controls the activities of the cell by regulating gene expres ...
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DNA Replication
In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule. DNA replication occurs in all living organisms acting as the most essential part for biological inheritance. This is essential for cell division during growth and repair of damaged tissues, while it also ensures that each of the new cells receives its own copy of the DNA. The cell possesses the distinctive property of division, which makes replication of DNA essential. DNA is made up of a double helix of two complementary strands. The double helix describes the appearance of a double-stranded DNA which is thus composed of two linear strands that run opposite to each other and twist together to form. During replication, these strands are separated. Each strand of the original DNA molecule then serves as a template for the production of its counterpart, a process referred to as semiconservative replication. As a result of semi-conservative rep ...
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Virus
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898,Dimmock p. 4 more than 9,000 virus species have been described in detail of the millions of types of viruses in the environment. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. The study of viruses is known as virology, a subspeciality of microbiology. When infected, a host cell is often forced to rapidly produce thousands of copies of the original virus. When not inside an infected cell or in the process of infecting a cell, viruses exist in the form of independent particles, or ''virions'', consisting of (i) the genetic material, i. ...
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