Lonchocarpus Urucu
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Lonchocarpus Urucu
''Lonchocarpus urucu'', or barbasco, is plant in the family Fabaceae. It is native to the tropical forests of Peru, as well as of Brazil and Guyana, growing from above sea level. It was also recorded in Venezuela. Cubé resin, the root extract from Barbasco and from cubé (''Lonchocarpus utilis''), is used as a commercial insecticide and piscicide (fish poison). The major active ingredients are rotenone and deguelin. Although "organic" (produced by nature), rotenone is no longer considered an environmentally safe chemical. Taxonomic status The taxonomic status as a species with the name Lonchocarpus urucu ist still to be resolved, as it is also considered a variety of Deguelia rufescens: ''Deguelia rufescens var. urucu'' (Killip & A.C.Sm.) A.M.G.Azeved. Toxicity Barbasco is toxic to insects, fish, and other pests. The primary threat to humans and other mammals comes from inhaling the powdered root or root extract. It has been used by the Shuar people of Ecuador and the Nukak p ...
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Ellsworth Paine Killip
Ellsworth Paine Killip (September 2, 1890 – November 21, 1968) was a United States, U.S. botanist. His name is linked to over 600 species names. Around 150 species are named for him, including ''Linanthus killipii''. Killip specialized in the taxonomy of South American plants. Killip joined the staff of the United States National Museum (USNM; now known as the Smithsonian Institution) in 1919 as an Aide in the Division of Plants. He was promoted to Assistant Curator in 1927, Associate Curator in 1928, and Curator in 1946. In 1947, Killip was appointed Head Curator of the newly established Department of Botany, USNM, a position he retained until his retirement in 1950. In 1925, ''Killipia'' was a genus of flowering plants from Colombia and Ecuador, belonging to the family Melastomataceae, named after him. It is now been downgraded to a synonym of ''Miconia''. References External links * Personal papersat Smithsonian Institution Archives at passionflow.co.uk Works
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Shuar People
The Shuar are an Indigenous people of Ecuador and Peru. They are members of the Jivaroan peoples, who are Amazonian tribes living at the headwaters of the Marañón River. Name Shuar, in the Shuar language, means "people". The people who speak the Shuar language live in tropical rainforest between the upper mountains of the Andes, and in the tropical rainforests and savannas of the Amazonian lowlands, in Ecuador extending to Peru. Shuar live in various places — thus, the ''muraiya'' (hill) Shuar are people who live in the foothills of the Andes; the ''achu'' (swamp-palm) shuar (or Achuar) are people who live in the wetter lowlands east of the Andes (Ecuador and Peru). Shuar refer to Spanish-Speakers as ''apach'', and to non-Spanish and non-Shuar speakers as ''inkis''. Europeans and European Americans used to refer to Shuar as "''jívaros''" or "''jíbaros''"; this word probably derives from the 16th century Spanish spelling of ''shuar'' (see Gnerre 1973), but has taken ot ...
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Flora Of Brazil
The wildlife of Brazil comprises all naturally occurring animals, plants, and fungi in the South American country. Home to 60% of the Amazon Rainforest, which accounts for approximately one-tenth of all species in the world, Brazil is considered to have the greatest biodiversity of any country on the planet. It has the most known species of plant Plants are predominantly photosynthetic eukaryotes of the kingdom Plantae. Historically, the plant kingdom encompassed all living things that were not animals, and included algae and fungi; however, all current definitions of Plantae exclud ...s (55,000), freshwater fish (3,000), and mammals (over 689). It also ranks third on the list of countries with the most bird species (1,832) and second with the most reptile species (744). The number of fungal species is unknown but is large.Da Silva, M. and D.W. Minter. 1995. ''Fungi from Brazil recorded by Batista and Co-workers''. Myc ...
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Lonchocarpus
''Lonchocarpus'' is a plant genus in the legume family (biology), family (Fabaceae). The species are called lancepods due to their fruit resembling an ornate lance tip or a few beads on a string. ''Cubé'' resin is produced from the roots of ''Lonchocarpus urucu, L. urucu'' and namely 'Lonchocarpus utilis, L. utilis'' (''cubé''). It contains enough of the toxic rotenoids rotenone and deguelin to be used as an insecticide and piscicide. As these are naturally occurring compounds, they were formerly used in organic farming. Since it is highly unselective and kills useful, as well as pest, animals, it is considered harmful to the environment today. Also, Chronic (medicine), chronic exposure to rotenone and deguelin seems to increase the risk of Parkinson's disease even in mammals, for which these compounds are less Acute (medicine), acutely toxic than for fish and insects. On the other hand, deguelin might be useful in cancer therapy if it can be applied directly into tumors, and ' ...
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Duke University
Duke University is a private research university in Durham, North Carolina. Founded by Methodists and Quakers in the present-day city of Trinity in 1838, the school moved to Durham in 1892. In 1924, tobacco and electric power industrialist James Buchanan Duke established The Duke Endowment and the institution changed its name to honor his deceased father, Washington Duke. The campus spans over on three contiguous sub-campuses in Durham, and a marine lab in Beaufort. The West Campus—designed largely by architect Julian Abele, an African American architect who graduated first in his class at the University of Pennsylvania School of Design—incorporates Gothic architecture with the Duke Chapel at the campus' center and highest point of elevation, is adjacent to the Medical Center. East Campus, away, home to all first-years, contains Georgian-style architecture. The university administers two concurrent schools in Asia, Duke-NUS Medical School in Singapore (established in ...
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Colombia
Colombia (, ; ), officially the Republic of Colombia, is a country in South America with insular regions in North America—near Nicaragua's Caribbean coast—as well as in the Pacific Ocean. The Colombian mainland is bordered by the Caribbean Sea to the north, Venezuela to the east and northeast, Brazil to the southeast, Ecuador and Peru to the south and southwest, the Pacific Ocean to the west, and Panama to the northwest. Colombia is divided into 32 departments and the Capital District of Bogotá, the country's largest city. It covers an area of 1,141,748 square kilometers (440,831 sq mi), and has a population of 52 million. Colombia's cultural heritage—including language, religion, cuisine, and art—reflects its history as a Spanish colony, fusing cultural elements brought by immigration from Europe and the Middle East, with those brought by enslaved Africans, as well as with those of the various Amerindian civilizations that predate colonization. Spanish is th ...
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Nukak People
The Nukak people (also Nukak- Makú) live between the Guaviare and Inírida rivers, in the depths of the tropical humid forest, on the fringe of the Amazon basin, in Guaviare Department, Republic of Colombia. They are nomadic hunter-gatherers with seasonal nomadic patterns and practice small-scale shifting horticulture.Mondragón, Héctor 1994 "La defensa del territorio Nukak" en Antropología y derechos Humanos. Memorias del VI Congreso de Antropología en Colombia. Carlos Vladimir Zambrano editor. Universidad de los Andes, p.p. 139 a 155. Bogotá D.C.- They were classified as "uncontacted people" until 1981, and have since lost half of their population primarily to disease. Part of their territory has been used by coca growers, ranchers, and other settlers, as well as being occupied by guerrillas, army and paramilitaries. Responses to this crisis include protests, requests for assimilation, and the suicide of leader Maw-be'. An estimated 210–250 Nukak people live in pr ...
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Ecuador
Ecuador ( ; ; Quechua: ''Ikwayur''; Shuar: ''Ecuador'' or ''Ekuatur''), officially the Republic of Ecuador ( es, República del Ecuador, which literally translates as "Republic of the Equator"; Quechua: ''Ikwadur Ripuwlika''; Shuar: ''Ekuatur Nunka''), is a country in northwestern South America, bordered by Colombia on the north, Peru on the east and south, and the Pacific Ocean on the west. Ecuador also includes the Galápagos Islands in the Pacific, about west of the mainland. The country's capital and largest city is Quito. The territories of modern-day Ecuador were once home to a variety of Indigenous groups that were gradually incorporated into the Inca Empire during the 15th century. The territory was colonized by Spain during the 16th century, achieving independence in 1820 as part of Gran Colombia, from which it emerged as its own sovereign state in 1830. The legacy of both empires is reflected in Ecuador's ethnically diverse population, with most of its mill ...
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Deguelin
Deguelin is a derivative of rotenone. Both are compounds classified as rotenoids of the flavonoid family and are naturally occurring insecticides. They can be produced by extraction from several plant species belonging to three genera of the legume family, Fabaceae: ''Lonchocarpus'', ''Derris'', or ''Tephrosia''. Cubé resin, the root extract from cubé (''Lonchocarpus utilis'') and from barbasco (''Lonchocarpus urucu''), is used as a commercial insecticide and piscicide (fish poison). The major active ingredients are rotenone and deguelin. Although "organic" (produced by nature) cubé resin is no longer considered environmentally safe. Rat pharmacokinetics * Mean residence time (MRT) = 6.98 h * Terminal half-life (t1/2(gamma)) = 9.26 h * Area under the curve (AUC) = 57.3 ng h/ml * Total clearance (Cl) = 4.37 L/h per kg * Apparent volume of distribution (V) = 3.421 L/kg * Volume of distribution at steady-state (Vss) = 30.46 L/kg * Tissue distributions after i.v. (intraveno ...
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Fabaceae
The Fabaceae or Leguminosae,International Code of Nomenclature for algae, fungi, and plants.
Article 18.5 states: "The following names, of long usage, are treated as validly published: ....Leguminosae (nom. alt.: Fabaceae; type: Faba Mill. Vicia L.; ... When the Papilionaceae are regarded as a family distinct from the remainder of the Leguminosae, the name Papilionaceae is conserved against Leguminosae." English pronunciations are as follows: , and .
commonly known as the legume, pea, or bean family, are a large and agriculturally important of

Rotenone
Rotenone is an odorless, colorless, crystalline isoflavone used as a broad-spectrum insecticide, piscicide, and pesticide. It occurs naturally in the seeds and stems of several plants, such as the jicama vine plant, and the roots of several members of Fabaceae. It was the first described member of the family of chemical compounds known as rotenoids. Discovery The earliest record of the now-known rotenone-containing plants used for killing leaf-eating caterpillars was in 1848, and for centuries, the same plants were used to poison fish. The active chemical component was first isolated in 1895 by a French botanist, Emmanuel Geoffroy, who called it ''nicouline'', from a specimen of ''Robinia nicou'', now called ''Lonchocarpus nicou'', while traveling in French Guiana. He wrote about this research in his thesis, published in 1895 after his death from a parasitic disease. In 1902 Kazuo Nagai, Japanese chemical engineer of the Government-General of Taiwan, isolated a pure crystalline ...
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Insecticide
Insecticides are substances used to kill insects. They include ovicides and larvicides used against insect eggs and larvae, respectively. Insecticides are used in agriculture, medicine, industry and by consumers. Insecticides are claimed to be a major factor behind the increase in the 20th-century's agricultural productivity. Nearly all insecticides have the potential to significantly alter ecosystems; many are toxic to humans and/or animals; some become concentrated as they spread along the food chain. Insecticides can be classified into two major groups: systemic insecticides, which have residual or long term activity; and contact insecticides, which have no residual activity. The mode of action describes how the pesticide kills or inactivates a pest. It provides another way of classifying insecticides. Mode of action can be important in understanding whether an insecticide will be toxic to unrelated species, such as fish, birds and mammals. Insecticides may be repellent ...
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