Legionellales
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Legionellales
The Legionellales are an order of Pseudomonadota. Like all Pseudomonadota, they are Gram-negative.George M. Garrity: ''Bergey's Manual of Systematic Bacteriology''. 2. Auflage. Springer, New York, 2005, Volume 2: ''The Proteobacteria, Part B: The Gammaproteobacteria'' They comprise two families, typified by ''Legionella'' and '' Coxiella'', both of which include notable pathogens. For example, Q fever is caused by ''Coxiella burnetii'' and ''Legionella pneumophila'' causes Legionnaires' disease and Pontiac fever. Members of the order ''Legionellales'' can be molecularly distinguished from other Gammaproteobacteria by the presence of four conserved signature indels Conserved signature inserts and deletions (CSIs) in protein sequences provide an important category of molecular markers for understanding phylogenetic relationships. CSIs, brought about by rare genetic changes, provide useful phylogenetic markers ... (CSIs) in the proteins tRNA-guanine(34) transglycosylase, lipoprotei ...
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Legionellales
The Legionellales are an order of Pseudomonadota. Like all Pseudomonadota, they are Gram-negative.George M. Garrity: ''Bergey's Manual of Systematic Bacteriology''. 2. Auflage. Springer, New York, 2005, Volume 2: ''The Proteobacteria, Part B: The Gammaproteobacteria'' They comprise two families, typified by ''Legionella'' and '' Coxiella'', both of which include notable pathogens. For example, Q fever is caused by ''Coxiella burnetii'' and ''Legionella pneumophila'' causes Legionnaires' disease and Pontiac fever. Members of the order ''Legionellales'' can be molecularly distinguished from other Gammaproteobacteria by the presence of four conserved signature indels Conserved signature inserts and deletions (CSIs) in protein sequences provide an important category of molecular markers for understanding phylogenetic relationships. CSIs, brought about by rare genetic changes, provide useful phylogenetic markers ... (CSIs) in the proteins tRNA-guanine(34) transglycosylase, lipoprotei ...
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Coxiella (bacterium)
''Coxiella'' refers to a genus of Gram-negative bacteria in the family Coxiellaceae. It is named after Herald Rea Cox (1907–1986), an American bacteriologist. It is one of the Gammaproteobacteria. ''Coxiella burnetii'' is the best known member of this genus. It is an intracellular parasite and it survives within the phagolysosomes of its host. It causes Q fever. The majority of ''Coxiella''’s described members are non pathogenic forms which are often found in ticks. Approximately two-thirds of tick species harbour ''Coxiella''-like endosymbionts required for tick survival and reproduction. Genomes of ''Coxiella''-like endosymbionts encode pathways for the biosynthesis of major B vitamins and co-factors that fit closely with the expected nutritional complements required for strict haematophagy. The experimental elimination of ''Coxiella''-like endosymbionts typically results in decreased tick survival, molting, fecundity and egg viability, as well as in physical abnormal ...
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Diplorickettsia
''Diplorickettsia massiliensis'' species is an obligate intracellular, gram negative bacterium isolated from Ixodes ricinus ticks collected in Slovak republic forest geographically from southeastern part of Rovinka in 2006.Mediannikov, O., et al.A novel obligate intracellular gamma-proteobacterium associated with ixodid ticks, Diplorickettsia massiliensis, Gen. Nov., Sp. Nov.''PLOS ONE'', 2010. 5(7): p. e11478. They belong to the gammaproteobacteria class and are non endospore forming, small rods usually grouped in pairs. The bacteria are non-motile, and 16S rRNA, rpoB, parC and ftsY gene sequencing indicate that this bacterium is clearly different from all other recognized species. An initial phylogenetic analysis based on 16S rRNA, clustered ''D. massiliensis'' with ''Rickettsiella grylli''. Because of its low 16S rDNA similarity (94%) with ''R. grylli'', it was classified as a new genus ''Diplorickettsia'' into the family ''Coxiellaceae'' and the order ''Legionellales''. ''D. ...
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Rickettsiella
''Rickettsiella'' is a genus of the family Coxiellaceae. It should not be confused with ''Rickettsia''. It is currently considered of the Gammaproteobacteria. However, its placement under Coxiellaceae instead of Legionellaceae has been challenged. Molecular Signatures and Taxonomy Members of the genera ''Rickettsiella'' and ''Diplorickettsia'' are observed to form a reliable clade in phylogenetic trees constructed from various datasets of concatenated protein sequences and 16S rRNA sequences, suggesting that they might belong to a single genus. Genomic analyses identified 12 conserved signature indels (CSIs) that are specific for this clade in the proteins inositol monophosphatase, lysyl-tRNA synthetase, elongation factor P-(R)-beta-lysine ligase, tol-Pal system beta propeller repeat protein TolB, FKBP-type peptidyl-prolyl cis-trans isomerase, response regulator transcription factor, 30S ribosomal protein S2, glycine cleavage system aminomethyltransferase GcvT, M3 family met ...
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Coxiellaceae
The Coxiellaceae are a family in the order Legionellales. ''Coxiella burnetii'' is a species in this order. Another is ''Rickettsiella melolonthae''. References Legionellales Bacteria families {{Legionellales-stub ...
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Legionellaceae
''Legionella'' is a genus of pathogenic gram-negative bacteria that includes the species '' L. pneumophila'', causing legionellosis (all illnesses caused by ''Legionella'') including a pneumonia-type illness called Legionnaires' disease and a mild flu-like illness called Pontiac fever. ''Legionella'' may be visualized with a silver stain or cultured in cysteine-containing media such as buffered charcoal yeast extract agar. It is common in many environments, including soil and aquatic systems, with at least 50 species and 70 serogroups identified. These bacteria, however, are not transmissible from person to person; furthermore, most people exposed to the bacteria do not become ill. Most outbreaks are traced to poorly maintained cooling towers. The side chains of the cell wall carry the bases responsible for the somatic antigen specificity of these organisms. The chemical composition of these side chains both with respect to components and arrangement of the different sugars det ...
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Legionella
''Legionella'' is a genus of pathogenic gram-negative bacteria that includes the species '' L. pneumophila'', causing legionellosis (all illnesses caused by ''Legionella'') including a pneumonia-type illness called Legionnaires' disease and a mild flu-like illness called Pontiac fever. ''Legionella'' may be visualized with a silver stain or cultured in cysteine-containing media such as buffered charcoal yeast extract agar. It is common in many environments, including soil and aquatic systems, with at least 50 species and 70 serogroups identified. These bacteria, however, are not transmissible from person to person; furthermore, most people exposed to the bacteria do not become ill. Most outbreaks are traced to poorly maintained cooling towers. The side chains of the cell wall carry the bases responsible for the somatic antigen specificity of these organisms. The chemical composition of these side chains both with respect to components and arrangement of the different sugars de ...
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Aquicella
''Aquicella'' is a genus of Gram-negative rod-shaped cells and filaments in the family ''Coxiellaceae'' from the order ''Legionellales''. The type species of this genus is ''Aquicella lusitana.'' The name ''Aquicella'' is composed of the Latin term ''aqua'' (referring to water) and the Latin term ''cella'' (referring to a chamber, closet, or cabinet, or in biology, a cell). Together, the name ''Aquicella'' translates to a cell from water. Biochemical Characteristics and Molecular Signatures Members of this genus grow in protozoa and can be isolated from hydrothermal areas. All members are strictly aerobic, non-motile, do not produce spores and are oxidase and catalase negative. ''Aquicella'' species can grow in temperatures ranging from 30 °C to 43 °C and require a neutral pH and growth media containing activated charcoal and a-ketoglutarate. Colonies appear whitish with a pink or blue sheen. Analyses of genome sequences from ''Aquicella'' species identified six co ...
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Gammaproteobacteria
Gammaproteobacteria is a class of bacteria in the phylum Pseudomonadota (synonym Proteobacteria). It contains about 250 genera, which makes it the most genera-rich taxon of the Prokaryotes. Several medically, ecologically, and scientifically important groups of bacteria belong to this class. It is composed by all Gram-negative microbes and is the most phylogenetically and physiologically diverse class of Proteobacteria. These microorganisms can live in several terrestrial and marine environments, in which they play various important roles, including ''extreme environments'' such as hydrothermal vents. They generally have different shapes - rods, curved rods, cocci, spirilla, and filaments and include free living bacteria, biofilm formers, commensals and symbionts, some also have the distinctive trait of being bioluminescent. Metabolisms found in the different genera are very different; there are both aerobic and anaerobic (obligate or facultative) species, chemolithoautotrophic ...
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Coxiella Burnetii
''Coxiella burnetii'' is an obligate intracellular bacterial pathogen, and is the causative agent of Q fever. The genus ''Coxiella'' is morphologically similar to ''Rickettsia'', but with a variety of genetic and physiological differences. ''C. burnetii'' is a small Gram-negative, coccobacillary bacterium that is highly resistant to environmental stresses such as high temperature, osmotic pressure, and ultraviolet light. These characteristics are attributed to a small cell variant form of the organism that is part of a biphasic developmental cycle, including a more metabolically and replicatively active large cell variant form. It can survive standard disinfectants, and is resistant to many other environmental changes like those presented in the phagolysosome. History and naming Research in the 1920s and 1930s identified what appeared to be a new type of ''Rickettsia'', isolated from ticks, that was able to pass through filters. The first description of what may have been ''Coxi ...
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Legionella Pneumophila
''Legionella pneumophila'' is a thin, aerobic, pleomorphic, flagellated, non-spore-forming, Gram-negative bacterium of the genus ''Legionella''. ''L. pneumophila'' is the primary human pathogenic bacterium in this group and is the causative agent of Legionnaires' disease, also known as legionellosis. In nature, ''L. pneumophila'' infects freshwater and soil amoebae of the genera ''Acanthamoeba'' and ''Naegleria''. The mechanism of infection is similar in amoeba and human cells. Characterization ''L. pneumophila'' is a Gram-negative, non-encapsulated, aerobic bacillus with a single, polar flagellum often characterized as being a coccobacillus. It is aerobic and unable to hydrolyse gelatin or produce urease. It is also non- fermentative. ''L. pneumophila'' is neither pigmented nor does it autofluoresce. It is oxidase- and catalase-positive, and produces beta-lactamase. ''L. pneumophila'' colony morphology is gray-white with a textured, cut-glass appearance; it also requires cyst ...
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Pontiac Fever
Pontiac fever is an acute, nonfatal respiratory disease caused by various species of Gram-negative bacteria in the genus ''Legionella''. It causes a mild upper respiratory infection that resembles acute influenza. Pontiac fever resolves spontaneously and often goes undiagnosed. Both Pontiac fever and the more severe Legionnaire's disease may be caused by the same bacteria, but Pontiac fever does not include pneumonia. Cause Species of ''Legionella'' known to cause Pontiac fever include ''Legionella pneumophila'', '' Legionella longbeachae'', ''Legionella feeleii'', ''Legionella micdadei'', and '' Legionella anisa''. Sources of the causative agents are aquatic systems and potting soil. The first outbreak caused by inhalation of aerosolized potting soil was discovered in New Zealand in January 2007. A total of 10 workers at a nursery came down with Pontiac fever. It was the first identification of ''L. longbeachae''. Pontiac fever does not spread from person to person. It is acquired ...
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