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Coxiellaceae
The Coxiellaceae are a family in the order Legionellales. ''Coxiella burnetii'' is a species in this order. Another is ''Rickettsiella melolonthae''. References Legionellales Bacteria families {{Legionellales-stub ...
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Diplorickettsia
''Diplorickettsia massiliensis'' species is an obligate intracellular, gram negative bacterium isolated from Ixodes ricinus ticks collected in Slovak republic forest geographically from southeastern part of Rovinka in 2006.Mediannikov, O., et al.A novel obligate intracellular gamma-proteobacterium associated with ixodid ticks, Diplorickettsia massiliensis, Gen. Nov., Sp. Nov.''PLOS ONE'', 2010. 5(7): p. e11478. They belong to the gammaproteobacteria class and are non endospore forming, small rods usually grouped in pairs. The bacteria are non-motile, and 16S rRNA, rpoB, parC and ftsY gene sequencing indicate that this bacterium is clearly different from all other recognized species. An initial phylogenetic analysis based on 16S rRNA, clustered ''D. massiliensis'' with ''Rickettsiella grylli''. Because of its low 16S rDNA similarity (94%) with ''R. grylli'', it was classified as a new genus ''Diplorickettsia'' into the family ''Coxiellaceae'' and the order ''Legionellales''. ''D. ...
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Rickettsiella
''Rickettsiella'' is a genus of the family Coxiellaceae. It should not be confused with ''Rickettsia''. It is currently considered of the Gammaproteobacteria. However, its placement under Coxiellaceae instead of Legionellaceae has been challenged. Molecular Signatures and Taxonomy Members of the genera ''Rickettsiella'' and ''Diplorickettsia'' are observed to form a reliable clade in phylogenetic trees constructed from various datasets of concatenated protein sequences and 16S rRNA sequences, suggesting that they might belong to a single genus. Genomic analyses identified 12 conserved signature indels (CSIs) that are specific for this clade in the proteins inositol monophosphatase, lysyl-tRNA synthetase, elongation factor P-(R)-beta-lysine ligase, tol-Pal system beta propeller repeat protein TolB, FKBP-type peptidyl-prolyl cis-trans isomerase, response regulator transcription factor, 30S ribosomal protein S2, glycine cleavage system aminomethyltransferase GcvT, M3 family met ...
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Coxiella (bacterium)
''Coxiella'' refers to a genus of Gram-negative bacteria in the family Coxiellaceae. It is named after Herald Rea Cox (1907–1986), an American bacteriologist. It is one of the Gammaproteobacteria. ''Coxiella burnetii'' is the best known member of this genus. It is an intracellular parasite and it survives within the phagolysosomes of its host. It causes Q fever. The majority of ''Coxiella''’s described members are non pathogenic forms which are often found in ticks. Approximately two-thirds of tick species harbour ''Coxiella''-like endosymbionts required for tick survival and reproduction. Genomes of ''Coxiella''-like endosymbionts encode pathways for the biosynthesis of major B vitamins and co-factors that fit closely with the expected nutritional complements required for strict haematophagy. The experimental elimination of ''Coxiella''-like endosymbionts typically results in decreased tick survival, molting, fecundity and egg viability, as well as in physical abnormal ...
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Aquicella
''Aquicella'' is a genus of Gram-negative rod-shaped cells and filaments in the family ''Coxiellaceae'' from the order ''Legionellales''. The type species of this genus is ''Aquicella lusitana.'' The name ''Aquicella'' is composed of the Latin term ''aqua'' (referring to water) and the Latin term ''cella'' (referring to a chamber, closet, or cabinet, or in biology, a cell). Together, the name ''Aquicella'' translates to a cell from water. Biochemical Characteristics and Molecular Signatures Members of this genus grow in protozoa and can be isolated from hydrothermal areas. All members are strictly aerobic, non-motile, do not produce spores and are oxidase and catalase negative. ''Aquicella'' species can grow in temperatures ranging from 30 °C to 43 °C and require a neutral pH and growth media containing activated charcoal and a-ketoglutarate. Colonies appear whitish with a pink or blue sheen. Analyses of genome sequences from ''Aquicella'' species identified six co ...
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Legionellales
The Legionellales are an order of Pseudomonadota. Like all Pseudomonadota, they are Gram-negative.George M. Garrity: ''Bergey's Manual of Systematic Bacteriology''. 2. Auflage. Springer, New York, 2005, Volume 2: ''The Proteobacteria, Part B: The Gammaproteobacteria'' They comprise two families, typified by ''Legionella'' and '' Coxiella'', both of which include notable pathogens. For example, Q fever is caused by ''Coxiella burnetii'' and ''Legionella pneumophila'' causes Legionnaires' disease and Pontiac fever. Members of the order ''Legionellales'' can be molecularly distinguished from other Gammaproteobacteria by the presence of four conserved signature indels Conserved signature inserts and deletions (CSIs) in protein sequences provide an important category of molecular markers for understanding phylogenetic relationships. CSIs, brought about by rare genetic changes, provide useful phylogenetic markers ... (CSIs) in the proteins tRNA-guanine(34) transglycosylase, lipoprotei ...
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Coxiella Burnetii
''Coxiella burnetii'' is an obligate intracellular bacterial pathogen, and is the causative agent of Q fever. The genus ''Coxiella'' is morphologically similar to ''Rickettsia'', but with a variety of genetic and physiological differences. ''C. burnetii'' is a small Gram-negative, coccobacillary bacterium that is highly resistant to environmental stresses such as high temperature, osmotic pressure, and ultraviolet light. These characteristics are attributed to a small cell variant form of the organism that is part of a biphasic developmental cycle, including a more metabolically and replicatively active large cell variant form. It can survive standard disinfectants, and is resistant to many other environmental changes like those presented in the phagolysosome. History and naming Research in the 1920s and 1930s identified what appeared to be a new type of ''Rickettsia'', isolated from ticks, that was able to pass through filters. The first description of what may have been ''Coxi ...
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Q Fever
Q fever or query fever is a disease caused by infection with ''Coxiella burnetii'', a bacterium that affects humans and other animals. This organism is uncommon, but may be found in cattle, sheep, goats, and other domestic mammals, including cats and dogs. The infection results from inhalation of a spore-like small-cell variant, and from contact with the milk, urine, feces, vaginal mucus, or semen of infected animals. Rarely, the disease is tick-borne. The incubation period is 9–40 days. Humans are vulnerable to Q fever, and infection can result from even a few organisms. The bacterium is an obligate intracellular pathogenic parasite. Signs and symptoms Incubation period is usually two to three weeks. The most common manifestation is flu-like symptoms: abrupt onset of fever, malaise, profuse perspiration, severe headache, muscle pain, joint pain, loss of appetite, upper respiratory problems, dry cough, pleuritic pain, chills, confusion, and gastrointestinal s ...
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Candidatus Berkiella
In prokaryote nomenclature, ''Candidatus'' (Latin for candidate of Roman office) is used to name prokaryotic phyla that are well characterized but yet-uncultured. Contemporary sequencing approaches, such as 16S sequencing or metagenomics, provide much information about the analyzed organisms and thus allow to identify and characterize individual species. However, the majority of prokaryotic species remain uncultivable and hence inaccessible for further characterization in ''in vitro'' study. The recent discoveries of a multitude of candidate taxa has led to candidate phyla radiation expanding the tree of life through the new insights in bacterial diversity. Nomenclature History The initial International Code of Nomenclature of Prokaryotes as well as early revisions did not account for the possibility of identifying prokaryotes which were not yet cultivable. Therefore, the term ''Candidatus'' was proposed in the context of a conference of the International Committee on Systemati ...
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