Lazzaro Spallanzani National Institute For Infectious Diseases
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Lazzaro Spallanzani National Institute For Infectious Diseases
The Lazzaro Spallanzani National Institute for Infectious Diseases (Italian: ''Istituto nazionale per le malattie infettive "L. Spallanzani"'') is an infectious disease hospital in the Italian city of Rome. The institute is named for the eighteenth-century Italian biologist Lazzaro Spallanzani. It is the Italian national reference center for Ebola patients. During the COVID-19 pandemic, the Spallanzani Institute was the first research centre in Europe to isolate the genomic sequence of SARS-CoV-2 and upload it to GenBank. The team was composed of Maria Rosaria Capobianchi, Francesca Colavita, and Concetta Castilletti. The institute is working with biotech company ReiThera to test a COVID-19 vaccine candidate called GRAd-COV2, which is based on a modified gorilla adenovirus Adenoviruses (members of the family ''Adenoviridae'') are medium-sized (90–100 nm), nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double-stranded ...
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Rome
, established_title = Founded , established_date = 753 BC , founder = King Romulus (legendary) , image_map = Map of comune of Rome (metropolitan city of Capital Rome, region Lazio, Italy).svg , map_caption = The territory of the ''comune'' (''Roma Capitale'', in red) inside the Metropolitan City of Rome (''Città Metropolitana di Roma'', in yellow). The white spot in the centre is Vatican City. , pushpin_map = Italy#Europe , pushpin_map_caption = Location within Italy##Location within Europe , pushpin_relief = yes , coordinates = , coor_pinpoint = , subdivision_type = Country , subdivision_name = Italy , subdivision_type2 = Region , subdivision_name2 = Lazio , subdivision_type3 = Metropolitan city , subdivision_name3 = Rome Capital , government_footnotes= , government_type = Strong Mayor–Council , leader_title2 = Legislature , leader_name2 = Capitoline Assemb ...
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GRAd-COV2
GRAd-COV2 is a COVID-19 vaccine candidate developed by ReiThera Srl and Lazzaro Spallanzani National Institute for Infectious Diseases. It is based on a novel replication defective Gorilla Adenovirus and encodes for SARS-COV-2 full length prefusion stabilized Spike protein. More specifically, the vector used is the simian group C adenovirus GRAd32, isolated from a captive gorilla, with a genome deleted of the entire E1 and E3 regions and the native E4 region replaced with the E4 orf6 of human adenovirus 5 (hAd5). References External links

Adenoviridae Clinical trials related to COVID-19 Italian COVID-19 vaccines Science and technology in Italy Viral vector vaccines {{COVID19-vaccine-stub ...
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Rome Q
, established_title = Founded , established_date = 753 BC , founder = King Romulus (Romulus and Remus, legendary) , image_map = Map of comune of Rome (metropolitan city of Capital Rome, region Lazio, Italy).svg , map_caption = The territory of the ''comune'' (''Roma Capitale'', in red) inside the Metropolitan City of Rome (''Città Metropolitana di Roma'', in yellow). The white spot in the centre is Vatican City. , pushpin_map = Italy#Europe , pushpin_map_caption = Location within Italy##Location within Europe , pushpin_relief = yes , coordinates = , coor_pinpoint = , subdivision_type = List of sovereign states, Country , subdivision_name = Italy , subdivision_type2 = Regions of Italy, Region , subdivision_name2 = Lazio , subdivision_type3 = Metropolitan cities of Italy, Metropolitan city , subdivision_name3 = Metropolitan City of Rome Capital, Rome Capital , government_footnotes= , ...
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Hospitals In Rome
A hospital is a health care institution providing patient treatment with specialized health science and auxiliary healthcare staff and medical equipment. The best-known type of hospital is the general hospital, which typically has an emergency department to treat urgent health problems ranging from fire and accident victims to a sudden illness. A district hospital typically is the major health care facility in its region, with many beds for intensive care and additional beds for patients who need long-term care. Specialized hospitals include trauma centers, rehabilitation hospitals, children's hospitals, seniors' (geriatric) hospitals, and hospitals for dealing with specific medical needs such as psychiatric treatment (see psychiatric hospital) and certain disease categories. Specialized hospitals can help reduce health care costs compared to general hospitals. Hospitals are classified as general, specialty, or government depending on the sources of income received. A teaching ...
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Agenzia Nazionale Stampa Associata
The Agenzia Nazionale Stampa Associata (ANSA; literally "National Associated Press Agency") is the leading news agency in Italy. ANSA is a not-for-profit cooperative, whose members and owners are 36 leading news organizations in Italy. Its mission is the distribution of fair and objective news reporting. History In January 1945, three representatives of the major political forces of the Italian Resistance, Giuseppe Liverani, managing director of "Il Popolo" (The People), Primo Parrini, managing director of Avanti!, and Amerigo Terenzi, CEO of L'Unità, advanced the possibility to organize a news agency as a cooperative of newspapers, not controlled by the government nor private groups, replacing the work of the Agenzia Stefani, moved to Milan to meet the information needs of the Italian Social Republic. Their proposal had the approval from the Allied military authorities who, a few months later, favored the success of the new agency by closing the Italian ''Notizie Nazioni Unite' ...
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Viral Vector
Viral vectors are tools commonly used by molecular biologists to deliver genetic material into cells. This process can be performed inside a living organism (''in vivo'') or in cell culture (''in vitro''). Viruses have evolved specialized molecular mechanisms to efficiently transport their genomes inside the cells they infect. Delivery of genes or other genetic material by a vector is termed transduction and the infected cells are described as transduced. Molecular biologists first harnessed this machinery in the 1970s. Paul Berg used a modified SV40 virus containing DNA from the bacteriophage λ to infect monkey kidney cells maintained in culture. In addition to their use in molecular biology research, viral vectors are used for gene therapy and the development of vaccines. Key properties of a viral vector VIRAL VECTORS are tailored to their specific applications but generally share a few key properties. *''Safety'': Although viral vectors are occasionally created from pathog ...
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Adenoviridae
Adenoviruses (members of the family ''Adenoviridae'') are medium-sized (90–100 nm), nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double-stranded DNA genome. Their name derives from their initial isolation from human adenoids in 1953. They have a broad range of vertebrate hosts; in humans, more than 50 distinct adenoviral serotypes have been found to cause a wide range of illnesses, from mild respiratory infections in young children (known as the common cold) to life-threatening multi-organ disease in people with a weakened immune system. Virology Classification This family contains the following genera: * '' Atadenovirus'' * '' Aviadenovirus'' * '' Ichtadenovirus'' * '' Mastadenovirus'' (including all human adenoviruses) * '' Siadenovirus'' * '' Testadenovirus'' Diversity In humans, currently there are 88 human adenoviruses (HAdVs) in seven species (Human adenovirus A to G): * A: 12, 18, 31 * B: 3, 7, 11, 14, ...
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Gorilla
Gorillas are herbivorous, predominantly ground-dwelling great apes that inhabit the tropical forests of equatorial Africa. The genus ''Gorilla'' is divided into two species: the eastern gorilla and the western gorilla, and either four or five subspecies. The DNA of gorillas is highly similar to that of humans, from 95 to 99% depending on what is included, and they are the next closest living relatives to humans after chimpanzees and bonobos. Gorillas are the largest living primates, reaching heights between 1.25 and 1.8 metres, weights between 100 and 270 kg, and arm spans up to 2.6 metres, depending on species and sex. They tend to live in troops, with the leader being called a silverback. The Eastern gorilla is distinguished from the Western by darker fur colour and some other minor morphological differences. Gorillas tend to live 35–40 years in the wild. The oldest gorilla known is Fatou (b. 1957), who is still alive at the advanced age of 65 years. Gorillas' ...
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COVID-19 Vaccine
A COVID19 vaccine is a vaccine intended to provide acquired immunity against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), the virus that causes coronavirus disease 2019 ( COVID19). Prior to the COVID19 pandemic, an established body of knowledge existed about the structure and function of coronaviruses causing diseases like severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). This knowledge accelerated the development of various vaccine platforms during early 2020. The initial focus of SARS-CoV-2 vaccines was on preventing symptomatic, often severe illness. In January 2020, the SARS-CoV-2 genetic sequence data was shared through GISAID, and by March 2020, the global pharmaceutical industry announced a major commitment to address COVID19. In 2020, the first COVID19 vaccines were developed and made available to the public through emergency authorizations and conditional approvals. Initially, most COVID19 vaccines were two ...
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Lazzaro Spallanzani
Lazzaro Spallanzani (; 12 January 1729 – 11 February 1799) was an Italian Catholic priest (for which he was nicknamed Abbé Spallanzani), biologist and physiologist who made important contributions to the experimental study of bodily functions, animal reproduction, and animal echolocation. His research on biogenesis paved the way for the downfall of the theory of spontaneous generation, a prevailing idea at the time that organisms develop from inanimate matters, though the final death blow to the idea was dealt by French scientist Louis Pasteur a century later. His most important works were summed up in his book ''Experiencias Para Servir a La Historia de La Generación De Animales y Plantas'' (''Experiences to Serve to the History of the Generation of Animals and Plants''), published in 1786. Among his contributions were experimental demonstrations of fertilisation between ova and spermatozoa, and ''in vitro'' fertilisation''.'' Biography Spallanzani was born in Scandian ...
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Sky TG24
Sky TG24 is Italy's second all-news channel, owned by Sky Italia. Launched on 31 July 2003, it provides non-stop rolling news, weather forecasts and sports stories with half-hourly updates. Overview Part of Sky TG24's programming is available on the television channels Cielo and TV8. In the United States, Sky TG24 is available on cable via RCN in Boston, Chicago, New York City, Philadelphia and Washington D.C.. From December 2004 to 7 December 2008 it was available via satellite on DirecTV. It was removed due to low subscriber levels. A local Canadian version of Sky TG24 airs in Canada. It is owned by Telelatino Network Inc. Most of its content is simulcast with the Italian channel, with Canadian content. The channel has been available in high definition since September 2013, making it the 63rd HDTV channel offered by Sky Italia Sky Italia S.r.l. is an Italian satellite television platform owned by the American media conglomerate Comcast. Sky Italia also broadca ...
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Maria Rosaria Capobianchi
Maria may refer to: People * Mary, mother of Jesus * Maria (given name), a popular given name in many languages Place names Extraterrestrial *170 Maria, a Main belt S-type asteroid discovered in 1877 * Lunar maria (plural of ''mare''), large, dark basaltic plains on Earth's Moon Terrestrial *Maria, Maevatanana, Madagascar * Maria, Quebec, Canada *Maria, Siquijor, the Philippines *María, Spain, in Andalusia *Îles Maria, French Polynesia * María de Huerva, Aragon, Spain * Villa Maria (other) Arts, entertainment, and media Films * ''Maria'' (1947 film), Swedish film * ''Maria'' (1975 film), Swedish film * ''Maria'' (2003 film), Romanian film * ''Maria'' (2019 film), Filipino film * ''Maria'' (2021 film), Canadian film directed by Alec Pronovost * ''Maria'' (Sinhala film), Sri Lankan upcoming film Literature * ''María'' (novel), an 1867 novel by Jorge Isaacs * ''Maria'' (Ukrainian novel), a 1934 novel by the Ukrainian writer Ulas Samchuk * ''Maria'' (play), a 1935 p ...
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