Lactobacillus Gasseri
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Lactobacillus Gasseri
''Lactobacillus gasseri'' is a species in the genus ''Lactobacillus'' identified in 1980 by François Gasser and his associates. It is part of the vaginal flora. Its genome has been sequenced. ''L. gasseri'' is a normal inhabitant of the lower reproductive tract in healthy women. It also produces Lactocillin. ''Lactobacillus gasseri'' produces gassericin A, a bacteriocin Bacteriocins are proteinaceous or peptidic toxins produced by bacteria to inhibit the growth of similar or closely related bacterial strain(s). They are similar to yeast and paramecium killing factors, and are structurally, functionally, and ec ....


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Lactobacillus
''Lactobacillus'' is a genus of Gram-positive, aerotolerant anaerobes or microaerophilic, rod-shaped, non-spore-forming bacteria. Until 2020, the genus ''Lactobacillus'' comprised over 260 phylogenetically, ecologically, and metabolically diverse species; a taxonomic revision of the genus assigned lactobacilli to 25 genera (see below). ''Lactobacillus'' species constitute a significant component of the human and animal microbiota at a number of body sites, such as the digestive system, and the female genital system. In women of European ancestry, ''Lactobacillus'' species are normally a major part of the vaginal microbiota. ''Lactobacillus'' forms biofilms in the vaginal and gut microbiota, allowing them to persist during harsh environmental conditions and maintain ample populations. ''Lactobacillus'' exhibits a mutualistic relationship with the human body, as it protects the host against potential invasions by pathogens, and in turn, the host provides a source of nutrien ...
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List Of Microbiota Species Of The Lower Reproductive Tract Of Women
This is the list of healthy vaginal microbiota (VMB), which is defined as the group of species and genera that generally are found to have lack of symptoms, absence of various infections, and result in good pregnancy outcomes. VMB is dominated mainly by Lactobacillus species. This is the list of organisms that are found in the lower reproductive tract of sexually mature women who are not immunocompromised. A partial description of pathogens that can be found in the lower and upper reproductive tract of women can be found in the article sexually transmitted disease. The organisms listed below are capable of causing illness if for some reason there is a change in vaginal pH or a change in the ratio of one organism to another. For example, '' Candida'' is a normal inhabitant of a healthy reproductive tract but an overgrowth of this organism can cause candidiasis. Normal microbiota This is the list of the normal flora that are found in the lower reproductive tract of sexually mat ...
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Lactocillin
Lactocillin is a thiopeptide antibiotic which is encoded for and produced by biosynthetic genes clusters in the bacteria ''Lactobacillus gasseri''. Lactocillin was discovered and purified in 2014. ''Lactobacillus gasseri'' is one of the four ''Lactobacillus'' bacteria found to be most common in the human vaginal microbiome. Due to increasing levels of pathogenic resistance to known antibiotics, novel antibiotics are increasingly valuable. Lactocillin could function as a new antibiotic that could help people fight off infections that are resistant to many other antibiotics. Biosynthetic Gene Clusters Lactocillin is produced by a biosynthetic gene cluster, which is a group of genes in bacteria that work together to make a secondary metabolite. Secondary metabolites are molecules with many different chemical structures and functions, and in this case, lactocillin functions as an antibiotic. Biosynthetic gene clusters are similar to operons in bacteria in that they both code for pr ...
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Bacteriocin
Bacteriocins are proteinaceous or peptidic toxins produced by bacteria to inhibit the growth of similar or closely related bacterial strain(s). They are similar to yeast and paramecium killing factors, and are structurally, functionally, and ecologically diverse. Applications of bacteriocins are being tested to assess their application as narrow-spectrum antibiotics. Bacteriocins were first discovered by André Gratia in 1925. He was involved in the process of searching for ways to kill bacteria, which also resulted in the development of antibiotics and the discovery of bacteriophage, all within a span of a few years. He called his first discovery a ''colicine'' because it killed ''E. coli.'' Classification Bacteriocins are categorized in several ways, including producing strain, common resistance mechanisms, and mechanism of killing. There are several large categories of bacteriocin which are only phenomenologically related. These include the bacteriocins from gram-posit ...
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Lactobacillaceae
The ''Lactobacillaceae'' are a family of lactic acid bacteria. It is the only family in the lactic acid bacteria which includes homofermentative and heterofermentative organisms; in the ''Lactobacillaceae,'' the pathway used for hexose fermentation is a genus-specific trait. ''Lactobacillaceae'' include the homofermentative lactobacilli ''Lactobacillus'', ''Holzapfelia'', ''Amylolactobacillus'', ''Bombilactobacillus'', ''Companilactobacillus'', ''Lapidilactobacillus'', ''Agrilactobacillus'', ''Schleiferilactobacillus'', ''Loigolactobacillus'', ''Lacticaseibacillus'', ''Latilactobacillus'', ''Dellaglioa'', ''Liquorilactobacillus'', ''Ligilactobacillus'', and ''Lactiplantibacillus''; the heterofermentative lactobacilli ''Furfurilactobacillus'', ''Paucilactobacillus'', ''Limosilactobacillus'', ''Fructilactobacillus'', ''Acetilactobacillus'', ''Apilactobacillus'', ''Levilactobacillus'', ''Secundilactobacillus'', and ''Lentilactobacillus,'' which were previously classified in the genus ...
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