Léopold Nègre
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Léopold Nègre
Léopold Nègre (15 June 1879 – 29 July 1961) was a French physician and biologist born in Montpellier. He studied natural sciences at the University of Montpellier, followed by courses in microbiology at the Pasteur Institute in Paris. From 1907 to 1910, he served as préparateur at the laboratory of microbiology courses headed by Amédée Borrel (1867–1936). In 1910, he obtained his doctorate of medicine. Following an internship at the Pasteur Institute in Lille, he was appointed laboratory chief (microbial analysis) at the Pasteur Institute in Algiers. In 1918 he received his doctorate of natural sciences. In 1919, he was assigned to the laboratory of tuberculosis headed by Albert Calmette (1863–1933) at the Pasteur Institute in Paris. Here he took part in research of Bacillus Calmette-Guérin (BCG vaccine). With microbiologist Alfred Boquet (1879–1947) he developed ''antigene méthylique'' (methyl antigen) for treatment of tuberculosis. In 1931, Nègre became cha ...
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Montpellier
Montpellier (, , ; oc, Montpelhièr ) is a city in southern France near the Mediterranean Sea. One of the largest urban centres in the region of Occitania (administrative region), Occitania, Montpellier is the prefecture of the Departments of France, department of Hérault. In 2018, 290,053 people lived in the city, while its Functional area (France), metropolitan area had a population of 787,705.Comparateur de territoire
INSEE, retrieved 20 June 2022.
The inhabitants are called Montpelliérains. In the Middle Ages, Montpellier was an important city of the Crown of Aragon (and was the birthplace of James I of Aragon, James I), and then of Kingdom of Majorca, Majorca, before its sale to France in 1349. Established in 1220, the University of Montpellier is one of the List of oldest univ ...
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Bacillus Calmette-Guérin
Bacillus Calmette–Guérin (BCG) vaccine is a vaccine primarily used against tuberculosis (TB). It is named after its inventors Albert Calmette and Camille Guérin. In countries where tuberculosis or leprosy is common, one dose is recommended in healthy babies as soon after birth as possible. In areas where tuberculosis is not common, only children at high risk are typically immunized, while suspected cases of tuberculosis are individually tested for and treated. Adults who do not have tuberculosis and have not been previously immunized, but are frequently exposed, may be immunized, as well. BCG also has some effectiveness against Buruli ulcer infection and other nontuberculous mycobacterial infections. Additionally, it is sometimes used as part of the treatment of bladder cancer. Rates of protection against tuberculosis infection vary widely and protection lasts up to 20 years. Among children, it prevents about 20% from getting infected and among those who do get infected, it ...
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Physicians From Montpellier
A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the study, diagnosis, prognosis and treatment of disease, injury, and other physical and mental impairments. Physicians may focus their practice on certain disease categories, types of patients, and methods of treatment—known as specialities—or they may assume responsibility for the provision of continuing and comprehensive medical care to individuals, families, and communities—known as general practice. Medical practice properly requires both a detailed knowledge of the academic disciplines, such as anatomy and physiology, underlying diseases and their treatment—the ''science'' of medicine—and also a decent competence in its applied practice—the art or ''craft'' of medicine. Both the role of the physician and the meaning ...
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French Microbiologists
French (french: français(e), link=no) may refer to: * Something of, from, or related to France ** French language, which originated in France, and its various dialects and accents ** French people, a nation and ethnic group identified with France ** French cuisine, cooking traditions and practices Fortnite French places Arts and media * The French (band), a British rock band * "French" (episode), a live-action episode of ''The Super Mario Bros. Super Show!'' * ''Française'' (film), 2008 * French Stewart (born 1964), American actor Other uses * French (surname), a surname (including a list of people with the name) * French (tunic), a particular type of military jacket or tunic used in the Russian Empire and Soviet Union * French's, an American brand of mustard condiment * French catheter scale, a unit of measurement of diameter * French Defence, a chess opening * French kiss, a type of kiss involving the tongue See also * France (other) * Franch, a surname * Frenc ...
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Epizootic Lymphangitis
Epizootic lymphangitis is a contagious lymphangitis disease of horses and mules caused by the fungus '' Histoplasma farciminosum''. Cattle are also susceptible, but more resistant to the disease than equids. See also glanders and equine lymphangitis. Classification In the United Kingdom it is a notifiable disease; the OIE no longer classifies it as a Listed Disease. Symptoms Epizootic lymphangitis usually presents with the following symptoms: * Skin eruption, usually on legs, occasionally head or neck, rarely other body parts. * The lymph vessels in the skin stand out prominently, and small hard nodules approximately 1 cm (1/2") in diameter appear on their course. * The nodules suppurate forming abscesses and discharge a thick yellow pus. Proud flesh grows from the wounds, the lymph vessels around being inflamed, and the eruption gradually extends. * The neighbouring glands are swollen and hard. The ulcers heal with difficulty, even under treatment, and they may ...
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Paratyphoid
Paratyphoid fever, also known simply as paratyphoid, is a bacterial infection caused by one of the three types of ''Salmonella enterica''. Symptoms usually begin 6–30 days after exposure and are the same as those of typhoid fever. Often, a gradual onset of a high fever occurs over several days. Weakness, loss of appetite, and headaches also commonly occur. Some people develop a skin rash with rose-colored spots. Without treatment, symptoms may last weeks or months. Other people may carry the bacteria without being affected; however, they are still able to spread the disease to others. Typhoid and paratyphoid are of similar severity. Paratyphoid and typhoid fever are types of enteric fever. Paratyphoid is caused by the bacterium ''Salmonella enterica'' of the serotypes Paratyphi A, Paratyphi B, or Paratyphi C growing in the intestines and blood. They are usually spread by eating or drinking food or water contaminated with the feces of an infected person. They may occur when a ...
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Typhoid
Typhoid fever, also known as typhoid, is a disease caused by '' Salmonella'' serotype Typhi bacteria. Symptoms vary from mild to severe, and usually begin six to 30 days after exposure. Often there is a gradual onset of a high fever over several days. This is commonly accompanied by weakness, abdominal pain, constipation, headaches, and mild vomiting. Some people develop a skin rash with rose colored spots. In severe cases, people may experience confusion. Without treatment, symptoms may last weeks or months. Diarrhea may be severe, but is uncommon. Other people may carry the bacterium without being affected, but they are still able to spread the disease. Typhoid fever is a type of enteric fever, along with paratyphoid fever. ''S. enterica'' Typhi is believed to infect and replicate only within humans. Typhoid is caused by the bacterium ''Salmonella enterica'' subsp. ''enterica'' serovar Typhi growing in the intestines, peyers patches, mesenteric lymph nodes, spleen, liver, ...
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Dysentery
Dysentery (UK pronunciation: , US: ), historically known as the bloody flux, is a type of gastroenteritis that results in bloody diarrhea. Other symptoms may include fever, abdominal pain, and a feeling of incomplete defecation. Complications may include dehydration. The cause of dysentery is usually the bacteria from genus ''Shigella'', in which case it is known as shigellosis, or the amoeba ''Entamoeba histolytica''; then it is called amoebiasis. Other causes may include certain chemicals, other bacteria, other protozoa, or parasitic worms. It may spread between people. Risk factors include contamination of food and water with feces due to poor sanitation. The underlying mechanism involves inflammation of the intestine, especially of the colon. Efforts to prevent dysentery include hand washing and food safety measures while traveling in areas of high risk. While the condition generally resolves on its own within a week, drinking sufficient fluids such as oral rehydration s ...
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Académie De Médecine
An academy ( Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of secondary or tertiary higher learning (and generally also research or honorary membership). The name traces back to Plato's school of philosophy, founded approximately 385 BC at Akademia, a sanctuary of Athena, the goddess of wisdom and skill, north of Athens, Greece. Etymology The word comes from the ''Academy'' in ancient Greece, which derives from the Athenian hero, '' Akademos''. Outside the city walls of Athens, the gymnasium was made famous by Plato as a center of learning. The sacred space, dedicated to the goddess of wisdom, Athena, had formerly been an olive grove, hence the expression "the groves of Academe". In these gardens, the philosopher Plato conversed with followers. Plato developed his sessions into a method of teaching philosophy and in 387 BC, established what is known today as the Old Academy. By extension, ''academia'' has come to mean the accumulatio ...
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Société De Biologie
The Société de biologie is a learned society founded in Paris in 1848. The society was conceived during the French Revolution of 1848. The members of the society held regular meetings and published the proceedings in a new scientific journal. The founding members of the society included Claude Bernard, the naturalist Charles-Philippe Robin, and the surgeon Eugène Follin. Its first president was the doctor and dermatologist Pierre Rayer. Bernard was unanimously elected president of the society in 1867 upon Rayer's death. Historian Mirko Grmek said the society brought together the best physiologists and naturalists in Paris, and that Bernard regularly attended the weekly meetings. During 1849 he spoke at nearly all the sessions. Of the 227 scientific articles published by Bernard from 1848 onwards, 79 of them were published in the ''Comptes-rendus et Mémoires de la Société de Biologie''. Marcellin Berthelot Pierre Eugène Marcellin Berthelot (; 25 October 1827 – 18 Ma ...
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Antigen
In immunology, an antigen (Ag) is a molecule or molecular structure or any foreign particulate matter or a pollen grain that can bind to a specific antibody or T-cell receptor. The presence of antigens in the body may trigger an immune response. The term ''antigen'' originally referred to a substance that is an antibody generator. Antigens can be proteins, peptides (amino acid chains), polysaccharides (chains of monosaccharides/simple sugars), lipids, or nucleic acids. Antigens are recognized by antigen receptors, including antibodies and T-cell receptors. Diverse antigen receptors are made by cells of the immune system so that each cell has a specificity for a single antigen. Upon exposure to an antigen, only the lymphocytes that recognize that antigen are activated and expanded, a process known as clonal selection. In most cases, an antibody can only react to and bind one specific antigen; in some instances, however, antibodies may cross-react and bind more than one antigen. ...
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Methyl
In organic chemistry, a methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms, having chemical formula . In formulas, the group is often abbreviated as Me. This hydrocarbon group occurs in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, bounded to the rest of the molecule by a single covalent bond (), it can be found on its own in any of three forms: methanide anion (), methylium cation () or methyl radical (). The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed. Methyl cation, anion, and radical Methyl cation The methylium cation () exists in the gas phase, but is otherwise not encountered. Some compounds are considered to be sources of the cation, and this simplification is used pervasively in organic chemistry. For example, protonation of methanol gives an elect ...
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