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Lundbeck
H. Lundbeck A/S (commonly known simply as Lundbeck) is a Danish international pharmaceutical company engaged in the research, development, manufacturing, marketing and sale of pharmaceuticals across the world. The company’s products are targeted at brain diseases, including depression, schizophrenia, Alzheimer's disease, Parkinson's disease and migraine. Headquartered in Copenhagen, Denmark, Lundbeck has approximately 5,300 employees in more than 50 countries, and their products are registered in more than 100 countries. They have production facilities in Denmark, France and Italy and their research centers are based in Denmark and the US. Lundbeck is listed on the Copenhagen Stock Exchange (CSE). Lundbeck is a full member of the European Federation of Pharmaceutical Industries and Associations (EFPIA) and of the International Federation of Pharmaceutical Manufacturers and Associations (IFPMA) History The company was founded by Hans Lundbeck in 1915, and was initially a tr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Citalopram
Citalopram, sold under the brand name Celexa among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used to treat major depressive disorder, obsessive compulsive disorder, panic disorder, and social phobia. The antidepressant effects may take one to four weeks to occur. It is taken by mouth. Common side effects include nausea, trouble sleeping, sexual problems, shakiness, feeling tired, and sweating. Serious side effects include an increased risk of suicide in those under the age of 25, serotonin syndrome, glaucoma, and QT prolongation. It should not be used in persons who take or have recently taken a MAO inhibitor. Antidepressant discontinuation syndrome may occur when stopped. There are concerns that use during pregnancy may harm the fetus. Citalopram was approved for medical use in the United States in 1998. It is on the WHO Model List of Essential Medicines, World Health Organization's List of Essential Medicines. It is avai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alder BioPharmaceuticals
Lundbeck Seattle Biopharmaceuticals is a pharmaceutical development company based in Bothell, Washington. Formerly known as Alder Biopharmaceuticals, it specializes in therapeutic monoclonal antibodies. In May 2014, Alder went public. In early 2018, the company made a public stock offering, aiming to raise . The company identifies, develops, and manufactures antibody therapeutics to alleviate human suffering in cancer, pain, cardiovascular, and autoimmune and inflammatory disease areas. As of September 2019, the Alder Biopharmaceuticals shares have increased with 83% in price, following the company's acquisition by the Denmark-based H. Lundbeck H. Lundbeck A/S (commonly known simply as Lundbeck) is a Danish international pharmaceutical company engaged in the research, development, manufacturing, marketing and sale of pharmaceuticals across the world. The company’s products are target ..., in a deal valued at $1.95 billion. The company subsequently changed its name to Lund ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aripiprazole
Aripiprazole, sold under the brand names Abilify and Aristada among others, is an atypical antipsychotic. It is primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders and irritability associated with autism. It is taken by mouth or injection into a muscle. A Cochrane review found low-quality evidence of effectiveness in treating schizophrenia. In adults, side effects with greater than 10% incidence include weight gain, headache, akathisia, insomnia, and gastro-intestinal effects like nausea and constipation, and lightheadedness. Side effects in children are similar, and include sleepiness, increased appetite, and stuffy nose. Common side effects include vomiting, constipation, sleepiness, dizziness, weight gain and movement disorders. Serious side effects may include neuroleptic malignant syndrome, tardive dyskinesia and anaphylaxis. It is not recommended for older people wi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Deborah Dunsire
Deborah Dunsire (b. 1963) is a medical doctor and pharmaceutical executive who has served as CEO of multiple research companies. Career At a 2013 career event at Bentley University, Dunsire remarked that she "...never intended to go into business. But after 9 months waiting for an ophthalmology residency to begin, she instead applied to a position as a clinical researcher" with Novartis. Novartis Dunsire started her career with Novartis in 1988 as an Executive Director of clinical research. She later rose to become Senior Vice President of North American oncology. During her tenure, she was responsible for the launch of blockbuster cancer therapy Gleevec (imatinib). Millennium Pharmaceuticals Dunsire was appointed CEO of Millennium Pharmaceuticals (later Takeda) in 2005, where she was known for her transformational leadership. Notably, she was the first female board member of Takeda when appointed in 2008. She left the company in 2013 after the role of CEO of Millennium was ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atypical Antipsychotic
The atypical antipsychotics (AAP), also known as second generation antipsychotics (SGAs) and serotonin–dopamine antagonists (SDAs), are a group of antipsychotic drugs (antipsychotic drugs in general are also known as major tranquilizers and neuroleptics, although the latter is usually reserved for the ''typical antipsychotics'') largely introduced after the 1970s and used to treat psychiatric conditions. Some atypical antipsychotics have received regulatory approval (e.g. by the Food and Drug Administration, FDA of the United States of America, US, the Therapeutic Goods Administration, TGA of Australia, the Medicines and Healthcare products Regulatory Agency, MHRA of the United Kingdom, UK) for schizophrenia, bipolar disorder, irritability in autism, and as an adjuvant therapy, adjunct in major depressive disorder. Both generations of medication tend to block receptors in the brain's dopamine pathways. Atypicals are less likely than haloperidol — the most widely used typi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Copenhagen
Copenhagen ( or .; da, København ) is the capital and most populous city of Denmark, with a proper population of around 815.000 in the last quarter of 2022; and some 1.370,000 in the urban area; and the wider Copenhagen metropolitan area has 2,057,142 people. Copenhagen is on the islands of Zealand and Amager, separated from Malmö, Sweden, by the Øresund strait. The Øresund Bridge connects the two cities by rail and road. Originally a Viking fishing village established in the 10th century in the vicinity of what is now Gammel Strand, Copenhagen became the capital of Denmark in the early 15th century. Beginning in the 17th century, it consolidated its position as a regional centre of power with its institutions, defences, and armed forces. During the Renaissance the city served as the de facto capital of the Kalmar Union, being the seat of monarchy, governing the majority of the present day Nordic region in a personal union with Sweden and Norway ruled by the Danis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chlorprothixene
Chlorprothixene, sold under the brand name Truxal among others, is a typical antipsychotic of the thioxanthene group. Medical uses Chlorprothixene's principal indications are the treatment of psychotic disorders (e.g. schizophrenia) and of acute mania occurring as part of bipolar disorders. Other uses are pre- and postoperative states with anxiety and insomnia, severe nausea / emesis (in hospitalized patients), the amelioration of anxiety and agitation due to use of selective serotonin reuptake inhibitors for depression and, off-label, the amelioration of alcohol and opioid withdrawal. It may also be used cautiously to treat nonpsychotic irritability, aggression, and insomnia in pediatric patients. An intrinsic antidepressant effect of chlorprothixene has been discussed, but not proven. Likewise, it is unclear if chlorprothixene has genuine (intrinsic) analgesic effects. However, chlorprothixene can be used as co-medication in severe chronic pain. Also, like most antipsych ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Indication (medicine)
In medicine, an indication is a valid reason to use a certain test, medication, procedure, or surgery. There can be multiple indications to use a procedure or medication. An indication can commonly be confused with the term diagnosis. A diagnosis is the assessment that a particular edicalcondition is present while an indication is a reason for use. The opposite of an indication is a contraindication, a reason to withhold a certain medical treatment because the risks of treatment clearly outweigh the benefits. In the United States, indications for prescription drugs are approved by the FDA. Indications are included in the Indications and Usage section of the Prescribing Information. The primary role of this section of labeling is to enable health care practitioners to readily identify appropriate therapies for patients by clearly communicating the drug’s approved indication(s). The Indications and Usage section states the disease or condition, or manifestation or symptoms thereof ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Millennium Pharmaceuticals
Takeda Oncology (originally Millennium Pharmaceuticals) is a biopharmaceutical company based in Cambridge, Massachusetts. It is a fully owned subsidiary of Takeda Pharmaceutical. Takeda Oncology's research, development and commercialization activities focused in two therapeutic areas: oncology and inflammation to develop a line of new product candidates. It was one of the first companies to systematically search for genes linked to disease, although none of the drugs which it is marketing or has in clinical trial, with one partial exception, have been the results of that research. It is particularly known for bringing bortezomib (marketed as Velcade) through clinical trials to approval for treatment of patients with multiple myeloma by the U.S. FDA, but has a growing clinical development pipeline of other product candidates. On May 14, 2008, Japanese company Takeda Pharmaceutical announced the completion of its acquisition of Millennium for US$25.00 per share in cash—a deal wo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chelsea Therapeutics
Chelsea or Chelsey may refer to: Places Australia * Chelsea, Victoria Canada * Chelsea, Nova Scotia * Chelsea, Quebec United Kingdom * Chelsea, London, an area of London, bounded to the south by the River Thames ** Chelsea (UK Parliament constituency), a former parliamentary constituency at Westminster until the 1997 redistribution ** Chelsea (London County Council constituency), 1949–1965 ** King's Road Chelsea railway station, a proposed railway station ** Chelsea Bridge, a bridge across the Thames ** Metropolitan Borough of Chelsea, a former borough in London United States * Chelsea, Alabama * Chelsea (Delaware City, Delaware), a historic house * Chelsea, Georgia * Chelsea, Indiana * Chelsea, Iowa, in Tama County * Chelsea, Maine * Chelsea, Massachusetts ** Bellingham Square station, which includes a commuter rail stop called Chelsea ** Chelsea station (MBTA), a bus rapid transit station in Chelsea * Chelsea, Michigan * Chelsey Brook, a stream in Minnesota * Chelsea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
