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Luis Agote
Luis Agote (September 22, 1868 – November 12, 1954) was an Argentine physician and researcher. He was the first to perform a non-direct blood transfusion using sodium citrate as an anticoagulant. The procedure took place in Rawson hospital in the city of Buenos Aires on November 9, 1914. Agote was the first to perform this procedure in the Americas. Agote worked independently and separately from the Belgian surgeon Albert Hustin, who discovered that sodium citrate in tolerable quantities could anticoagulate blood for transfusion on March 27, 1914. Biography Agote was the son of a politician. He studied first in the Colegio Nacional de Buenos Aires, and then at the University of Buenos Aires Faculty of Medicine, where he was also a teacher. He graduated as a doctor in 1893 with a thesis about suppurative hepatitis. He became Secretary of the National Department of Hygiene in 1894 and became head of the leper hospital in 1895 on the island of Martin Garcia. He was elected Congre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Luis Agote
Luis Agote (September 22, 1868 – November 12, 1954) was an Argentine physician and researcher. He was the first to perform a non-direct blood transfusion using sodium citrate as an anticoagulant. The procedure took place in Rawson hospital in the city of Buenos Aires on November 9, 1914. Agote was the first to perform this procedure in the Americas. Agote worked independently and separately from the Belgian surgeon Albert Hustin, who discovered that sodium citrate in tolerable quantities could anticoagulate blood for transfusion on March 27, 1914. Biography Agote was the son of a politician. He studied first in the Colegio Nacional de Buenos Aires, and then at the University of Buenos Aires Faculty of Medicine, where he was also a teacher. He graduated as a doctor in 1893 with a thesis about suppurative hepatitis. He became Secretary of the National Department of Hygiene in 1894 and became head of the leper hospital in 1895 on the island of Martin Garcia. He was elected Congre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Agote 1a Transfusión
The ''Cagots'' () were a persecuted minority found in the west of France and northern Spain: the Navarrese Pyrenees, Basque provinces, Béarn, Aragón, Gascony and Brittany. Evidence of the group exists as far back as 1000 CE. Name Etymology The origins of both the term (and , , , etc.) and the Cagots themselves are uncertain. It has been suggested that they were descendants of the Visigoths defeated by Clovis I at the Battle of Vouillé,: "" Antoine_Court_de_Gébelin">Court_de_Gebelin''_in_his__chooses_the_''Alans''_and_cites_the_Court_de_Gebelin''_in_his__chooses_the_''Alans">Antoine_Court_de_Gébelin">Court_de_Gebelin''_in_his__chooses_the_''Alans''_and_cites_the_Battle_of_Orleans_(463)">battle_of_463,_in_which_they_were_defeated_with_the_Visigoths._'' Court_de_Gebelin''_in_his__chooses_the_''Alans">Antoine_Court_de_Gébelin">Court_de_Gebelin''_in_his__chooses_the_''Alans''_and_cites_the_Battle_of_Orleans_(463)">battle_of_463,_in_which_they_were_defeated_with_the_Visig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Burials At La Recoleta Cemetery
Burial, also known as interment or inhumation, is a method of final disposition whereby a dead body is placed into the ground, sometimes with objects. This is usually accomplished by excavating a pit or trench, placing the deceased and objects in it, and covering it over. A funeral is a ceremony that accompanies the final disposition. Humans have been burying their dead since shortly after the origin of the species. Burial is often seen as indicating respect for the dead. It has been used to prevent the odor of decay, to give family members closure and prevent them from witnessing the decomposition of their loved ones, and in many cultures it has been seen as a necessary step for the deceased to enter the afterlife or to give back to the cycle of life. Methods of burial may be heavily ritualized and can include natural burial (sometimes called "green burial"); embalming or mummification; and the use of containers for the dead, such as shrouds, coffins, grave liners, and bur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Buenos Aires Alumni
A university () is an educational institution, institution of higher education, higher (or Tertiary education, tertiary) education and research which awards academic degrees in several Discipline (academia), academic disciplines. Universities typically offer both undergraduate education, undergraduate and postgraduate education, postgraduate programs. In the United States, the designation is reserved for colleges that have a graduate school. The word ''university'' is derived from the Latin ''universitas magistrorum et scholarium'', which roughly means "community of teachers and scholars". The first universities were created in Europe by Catholic Church monks. The University of Bologna (''Università di Bologna''), founded in 1088, is the first university in the sense of: *Being a high degree-awarding institute. *Having independence from the ecclesiastic schools, although conducted by both clergy and non-clergy. *Using the word ''universitas'' (which was coined at its foundation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
People From Buenos Aires
A person ( : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its use as a plural form of pe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Argentine Physicians
Argentines (mistakenly translated Argentineans in the past; in Spanish (masculine) or (feminine)) are people identified with the country of Argentina. This connection may be residential, legal, historical or cultural. For most Argentines, several (or all) of these connections exist and are collectively the source of their being ''Argentine''. Argentina is a multiethnic and multilingual society, home to people of various ethnic, religious, and national origins, with the majority of the population made up of Old World immigrants and their descendants. As a result, Argentines do not equate their nationality with ethnicity, but with citizenship and allegiance to Argentina. Aside from the indigenous population, nearly all Argentines or their ancestors immigrated within the past five centuries. Among countries in the world that have received the most immigrants in modern history, Argentina, with 6.6 million, ranks second to the United States (27 million), and ahead of other immigr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Argentine Inventors
Argentines (mistakenly translated Argentineans in the past; in Spanish (masculine) or (feminine)) are people identified with the country of Argentina. This connection may be residential, legal, historical or cultural. For most Argentines, several (or all) of these connections exist and are collectively the source of their being ''Argentine''. Argentina is a multiethnic and multilingual society, home to people of various ethnic, religious, and national origins, with the majority of the population made up of Old World immigrants and their descendants. As a result, Argentines do not equate their nationality with ethnicity, but with citizenship and allegiance to Argentina. Aside from the indigenous population, nearly all Argentines or their ancestors immigrated within the past five centuries. Among countries in the world that have received the most immigrants in modern history, Argentina, with 6.6 million, ranks second to the United States (27 million), and ahead of other immigr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1954 Deaths
Events January * January 1 – The Soviet Union ceases to demand war reparations from West Germany. * January 3 – The Italian broadcaster RAI officially begins transmitting. * January 7 – Georgetown-IBM experiment: The first public demonstration of a machine translation system is held in New York, at the head office of IBM. * January 10 – BOAC Flight 781, a de Havilland Comet jet plane, disintegrates in mid-air due to metal fatigue, and crashes in the Mediterranean near Elba; all 35 people on board are killed. * January 12 – Avalanches in Austria kill more than 200. * January 15 – Mau Mau leader Waruhiu Itote is captured in Kenya. * January 17 – In Yugoslavia, Milovan Đilas, one of the leading members of the League of Communists of Yugoslavia, is relieved of his duties. * January 20 – The US-based National Negro Network is established, with 46 member radio stations. * January 21 – The first nuclear-powered subm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1868 Births
Events January–March * January 2 – British Expedition to Abyssinia: Robert Napier leads an expedition to free captive British officials and missionaries. * January 3 – The 15-year-old Mutsuhito, Emperor Meiji of Japan, declares the ''Meiji Restoration'', his own restoration to full power, under the influence of supporters from the Chōshū and Satsuma Domains, and against the supporters of the Tokugawa shogunate, triggering the Boshin War. * January 5 – Paraguayan War: Brazilian Army commander Luís Alves de Lima e Silva, Duke of Caxias enters Asunción, Paraguay's capital. Some days later he declares the war is over. Nevertheless, Francisco Solano López, Paraguay's president, prepares guerrillas to fight in the countryside. * January 7 – The Arkansas constitutional convention meets in Little Rock. * January 9 – Penal transportation from Britain to Australia ends, with arrival of the convict ship ''Hougoumont'' in Western Aus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thrombin
Thrombin (, ''fibrinogenase'', ''thrombase'', ''thrombofort'', ''topical'', ''thrombin-C'', ''tropostasin'', ''activated blood-coagulation factor II'', ''blood-coagulation factor IIa'', ''factor IIa'', ''E thrombin'', ''beta-thrombin'', ''gamma-thrombin'') is a serine protease, an enzyme that, in humans, is encoded by the ''F2'' gene. Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the clotting process. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions. History After the description of fibrinogen and fibrin, Alexander Schmidt hypothesised the existence of an enzyme that converts fibrinogen into fibrin in 1872. Prothrombin was discovered by Pekelharing in 1894. Physiology Synthesis Thrombin is produced by the enzymatic cleavage of two sites on prothrombin by activated Factor X (Xa). The activity of factor Xa is greatly ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fibrin
Fibrin (also called Factor Ia) is a fibrous, non-globular protein involved in the clotting of blood. It is formed by the action of the protease thrombin on fibrinogen, which causes it to polymerize. The polymerized fibrin, together with platelets, forms a hemostatic plug or clot over a wound site. When the lining of a blood vessel is broken, platelets are attracted, forming a platelet plug. These platelets have thrombin receptors on their surfaces that bind serum thrombin molecules, which in turn convert soluble fibrinogen in the serum into fibrin at the wound site. Fibrin forms long strands of tough insoluble protein that are bound to the platelets. Factor XIII completes the cross-linking of fibrin so that it hardens and contracts. The cross-linked fibrin forms a mesh atop the platelet plug that completes the clot. Fibrin was discovered by Marcello Malpighi in 1666. Role in disease Excessive generation of fibrin due to activation of the coagulation cascade leads to thrombos ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coagulation
Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot. It potentially results in hemostasis, the cessation of blood loss from a damaged vessel, followed by repair. The mechanism of coagulation involves activation, adhesion and aggregation of platelets, as well as deposition and maturation of fibrin. Coagulation begins almost instantly after an injury to the endothelium lining a blood vessel. Exposure of blood to the subendothelial space initiates two processes: changes in platelets, and the exposure of subendothelial tissue factor to plasma factor VII, which ultimately leads to cross-linked fibrin formation. Platelets immediately form a plug at the site of injury; this is called ''primary hemostasis. Secondary hemostasis'' occurs simultaneously: additional coagulation (clotting) factors beyond factor VII ( listed below) respond in a cascade to form fibrin strands, which strengthen the platelet plug. Disorders of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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