Louping Ill
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Louping Ill
Louping-ill () is an acute viral disease primarily of sheep that is characterized by a biphasic fever, depression, ataxia, muscular incoordination, tremors, posterior paralysis, coma, and death. Louping-ill is a tick-transmitted disease whose occurrence is closely related to the distribution of the primary vector, the sheep tick ''Ixodes ricinus''. It also causes disease in red grouse, and can affect humans. The name 'louping-ill' is derived from an old Scottish word describing the effect of the disease in sheep whereby they 'loup' or spring into the air. Cause Louping ill is caused by RNA virus called Louping ill virus. Louping ill virus belongs to genus ''Flavivirus'', family Flaviviridae. There are four subtypes: British, Irish, Spanish and Turkish. Prevention According to a ProMED article, disease in sheep has been controlled in the UK by a vaccine (ATCvet code: QI04AA01), originally developed by Scotland's Moredun Research Institute by Prof John Russell Greig John ...
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Veterinary Medicine
Veterinary medicine is the branch of medicine that deals with the prevention, management, diagnosis, and treatment of disease, disorder, and injury in animals. Along with this, it deals with animal rearing, husbandry, breeding, research on nutrition, and product development. The scope of veterinary medicine is wide, covering all animal species, both domesticated and wild, with a wide range of conditions that can affect different species. Veterinary medicine is widely practiced, both with and without professional supervision. Professional care is most often led by a veterinary physician (also known as a veterinarian, veterinary surgeon, or "vet"), but also by paraveterinary workers, such as veterinary nurses or technicians. This can be augmented by other paraprofessionals with specific specialties, such as animal physiotherapy or dentistry, and species-relevant roles such as farriers. Veterinary science helps human health through the monitoring and control of zoonotic disease ...
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Red Grouse
The red grouse (''Lagopus lagopus scotica'') is a medium-sized bird of the grouse family which is found in heather moorland in Great Britain and Ireland. It is usually classified as a subspecies of the willow ptarmigan but is sometimes considered to be a separate species, ''Lagopus scoticus''. It is also known as the moorcock, moorfowl or moorbird. ''Lagopus'' is derived from Ancient Greek (), meaning "hare", + (), "foot", in reference to the feathered feet and toes typical of this cold-adapted genus, and ''scoticus'' is "of Scotland". The red grouse is the logo of The Famous Grouse whisky and an animated bird is a character in a series of its adverts. The red grouse is also the emblem of the journal '' British Birds''. Description The red grouse is differentiated from the willow ptarmigan and rock ptarmigan by its plumage being reddish brown, and not having a white winter plumage. The tail is black and the legs are white. There are white stripes on the underwing and red co ...
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Animal Viral Diseases
Animals are multicellular, eukaryotic organisms in the biological kingdom Animalia. With few exceptions, animals consume organic material, breathe oxygen, are able to move, can reproduce sexually, and go through an ontogenetic stage in which their body consists of a hollow sphere of cells, the blastula, during embryonic development. Over 1.5 million living animal species have been described—of which around 1 million are insects—but it has been estimated there are over 7 million animal species in total. Animals range in length from to . They have complex interactions with each other and their environments, forming intricate food webs. The scientific study of animals is known as zoology. Most living animal species are in Bilateria, a clade whose members have a bilaterally symmetric body plan. The Bilateria include the protostomes, containing animals such as nematodes, arthropods, flatworms, annelids and molluscs, and the deuterostomes, containing the echinoderms an ...
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Sheep And Goat Diseases
Sheep or domestic sheep (''Ovis aries'') are domesticated, ruminant mammals typically kept as livestock. Although the term ''sheep'' can apply to other species in the genus ''Ovis'', in everyday usage it almost always refers to domesticated sheep. Like all ruminants, sheep are members of the order Artiodactyla, the even-toed ungulates. Numbering a little over one billion, domestic sheep are also the most numerous species of sheep. An adult female is referred to as a ''ewe'' (), an intact male as a ''ram'', occasionally a ''tup'', a castrated male as a ''wether'', and a young sheep as a ''lamb''. Sheep are most likely descended from the wild mouflon of Europe and Asia, with Iran being a geographic envelope of the domestication center. One of the earliest animals to be domesticated for agricultural purposes, sheep are raised for fleeces, meat (lamb, hogget or mutton) and milk. A sheep's wool is the most widely used animal fiber, and is usually harvested by shearing. In Commonwea ...
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John Russell Greig
John McDougal Russell Greig CBE FRSE MRCVS (September 1889-1 May 1963) was a Scottish veterinarian who was Director of the Moredun Research Institute from 1930 to 1954. He is noted for the development of several important animal vaccines: Enzootic abortion in ewes; Braxy and Louping ill. His work on milk effectively created "clean milk" for the first time in Britain. Life He was born in Leith on 8 September 1889 the son of William Carmichael Greig (1851-1929), a grocer, and his wife Mary McDougal (1852-1934). They lived in a second floor flat at 101 Ferry Road, which was then just newly built. He was educated at the Royal High School in Edinburgh. In 1906 he entered the Royal (Dick) School of Veterinary Studies. He completed his studies in 1911 and was admitted a member of the Royal College of Veterinary Surgeons. He then began working in the Veterinary Department of the City of Glasgow. He self-financed a trip to Copenhagen to meet Bernhard Bang and learn of his studies on bo ...
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Moredun Research Institute
The Moredun Research Institute is a scientific research institution based at the Pentlands Science Park, in the Bush Estate area of Midlothian, Scotland. It conducts research into diseases of farm livestock and the promotion of animal health and welfare. Moredun employs over 200 vets, scientists and support staff, that are funded primarily by the Agriculture, Food and Rural Communities Directorate of the Scottish Government. The Institute received £7.1 million from the government in 2010–11.National Public Bodies Directory
the Scottish Government


History

The Animal Diseases Research Association, now the registered charity the Moredun Foundation, was founded in 1920 by a group of Scottish farmers, with the aim of improving the health of livestock, especially

ATCvet
The Anatomical Therapeutic Chemical (ATC) Classification System is a drug classification system that classifies the active ingredients of drugs according to the organ or system on which they act and their therapeutic, pharmacological and chemical properties. Its purpose is an aid to monitor drug use and for research to improve quality medication use. It does not imply drug recommendation or efficacy. It is controlled by the World Health Organization Collaborating Centre for Drug Statistics Methodology (WHOCC), and was first published in 1976. Coding system This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act, their therapeutic intent or nature, and the drug's chemical characteristics. Different brands share the same code if they have the same active substance and indications. Each bottom-level ATC code stands for a pharmaceutically used substance, or a combination of substances, in a single indication (or us ...
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ProMED-mail
Program for Monitoring Emerging Diseases (also known as ProMED-mail, abbreviated ProMED) is among the largest publicly available emerging diseases and outbreak reporting systems in the world. The purpose of ProMED is to promote communication amongst the international infectious disease community, including scientists, physicians, veterinarians, epidemiologists, public health professionals, and others interested in infectious diseases on a global scale. Founded in 1994, ProMED has pioneered the concept of electronic, Internet-based emerging disease and outbreak detection reporting. In 1999, ProMED became a program of the International Society for Infectious Diseases. As of 2016, ProMED has more than 75,000 subscribers in over 185 countries. With an average of 13 posts per day, ProMED provides users with up-to-date information concerning infectious disease outbreaks on a global scale. ProMED's guiding principles include: * Transparency and a commitment to the unfettered flow of outb ...
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Flavivirus
''Flavivirus'' is a genus of positive-strand RNA viruses in the family ''Flaviviridae''. The genus includes the West Nile virus, dengue virus, tick-borne encephalitis virus, yellow fever virus, Zika virus and several other viruses which may cause encephalitis, as well as insect-specific flaviviruses (ISFs) such as cell fusing agent virus (CFAV), Palm Creek virus (PCV), and Parramatta River virus (PaRV). While dual-host flaviviruses can infect vertebrates as well as arthropods, insect-specific flaviviruses are restricted to their competent arthropods. The means by which flaviviruses establish persistent infection in their competent vectors and cause disease in humans depends upon several virus-host interactions, including the intricate interplay between flavivirus-encoded immune antagonists and the host antiviral innate immune effector molecules. Flaviviruses are named for the yellow fever virus; the word ''flavus'' means 'yellow' in Latin, and yellow fever in turn is named from i ...
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Ixodes Ricinus
''Ixodes ricinus'', the castor bean tick, is a chiefly European species of hard-bodied tick. It may reach a length of when engorged with a blood meal, and can transmit both bacterial and viral pathogens such as the causative agents of Lyme disease and tick-borne encephalitis. Description In common with other species of ''Ixodes'', ''I. ricinus'' has no eyes and is not ornate; it has no festoons (wrinkles along the posterior margin). The palpi are longer than they are wide, and an anal groove is above the anus. It has a hard dorsal shield which covers the entire opisthosoma (abdomen), but only part of it in females and nymphs. ''I. ricinus'' is the largest of the three common species of ''Ixodes'' in the British Isles (the other two being '' I. canisuga'', the British dog tick, and '' I. trianguliceps'', the vole tick). Adult males are long, and unfed nymphs are long; females are long before feeding and long when engorged. Distribution ''Ixodes rici ...
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Sheep
Sheep or domestic sheep (''Ovis aries'') are domesticated, ruminant mammals typically kept as livestock. Although the term ''sheep'' can apply to other species in the genus ''Ovis'', in everyday usage it almost always refers to domesticated sheep. Like all ruminants, sheep are members of the order Artiodactyla, the even-toed ungulates. Numbering a little over one billion, domestic sheep are also the most numerous species of sheep. An adult female is referred to as a ''ewe'' (), an intact male as a ''ram'', occasionally a ''tup'', a castrated male as a ''wether'', and a young sheep as a ''lamb''. Sheep are most likely descended from the wild mouflon of Europe and Asia, with Iran being a geographic envelope of the domestication center. One of the earliest animals to be domesticated for agricultural purposes, sheep are raised for fleeces, meat (lamb, hogget or mutton) and milk. A sheep's wool is the most widely used animal fiber, and is usually harvested by shearing. In Commonw ...
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Tick
Ticks (order Ixodida) are parasitic arachnids that are part of the mite superorder Parasitiformes. Adult ticks are approximately 3 to 5 mm in length depending on age, sex, species, and "fullness". Ticks are external parasites, living by feeding on the blood of mammals, birds, and sometimes reptiles and amphibians. The timing of the origin of ticks is uncertain, though the oldest known tick fossils are from the Cretaceous period, around 100 million years old. Ticks are widely distributed around the world, especially in warm, humid climates. Ticks belong to two major families, the Ixodidae or hard ticks, and the Argasidae, or soft ticks. ''Nuttalliella,'' a genus of tick from southern Africa is the only member of the family Nuttalliellidae, and represents the most primitive living lineage of ticks. Adults have ovoid/pear-shaped bodies (idiosomas) which become engorged with blood when they feed, and eight legs. Their cephalothorax and abdomen are completely fused. In addit ...
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