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Lofenalac
Lofenalac (pronunciation:Lo-fen-alac) is a registered, trademarked infant powder formula prescribed to replace milk in the diets of phenylketonuria sufferers in the infant and child stage. It is not recommended for non-PKU patients. In 1972, Lofenalac was declared a food by the FDA, for regulatory purposes. Initially the only available formula recommended was made by Mead Johnson Mead Johnson & Company, LLC is an American company that is a leading manufacturer of infant formula, both domestically and globally, with its flagship product Enfamil. It operates as an independent subsidiary of Reckitt. The company dates back t .... Others, including Albumaid XP, Cymogran, and Minafen, have since been developed in Britain. Medical texts often recommend Lofenalac. Lofenalac can be rather expensive to purchase and few retailers stock it. The taste and smell has been described by adult users as "medical" and offensive, although infants do not mind the flavor and children often consume ...
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Phenylketonuria
Phenylketonuria (PKU) is an inborn error of metabolism that results in decreased metabolism of the amino acid phenylalanine. Untreated PKU can lead to intellectual disability, seizures, behavioral problems, and mental disorders. It may also result in a musty smell and lighter skin. A baby born to a mother who has poorly treated PKU may have heart problems, a small head, and low birth weight. Phenylketonuria is an inherited genetic disorder. It is due to mutations in the '' PAH'' gene, which results in low levels of the enzyme phenylalanine hydroxylase. This results in the buildup of dietary phenylalanine to potentially toxic levels. It is autosomal recessive, meaning that both copies of the gene must be mutated for the condition to develop. There are two main types, classic PKU and variant PKU, depending on whether any enzyme function remains. Those with one copy of a mutated gene typically do not have symptoms. Many countries have newborn screening programs for the disease. ...
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Casein
Casein ( , from Latin ''caseus'' "cheese") is a family of related phosphoproteins (CSN1S1, αS1, aS2, CSN2, β, K-casein, κ) that are commonly found in mammalian milk, comprising about 80% of the proteins in cow's milk and between 20% and 60% of the proteins in breast milk, human milk. Sheep's milk, Sheep and buffalo milk have a higher casein content than other types of milk with human milk having a particularly low casein content. Casein has a wide variety of uses, from being a major component of cheese, to use as a food additive. The most common form of casein is sodium caseinate. In milk, casein undergoes phase separation to form colloidal casein micelles, a type of secreted biomolecular condensate. As a food source, casein supplies amino acids, carbohydrates, and two essential elements, calcium and phosphorus. Composition Casein contains a high number of proline amino acids which hinder the formation of common secondary structural motifs of proteins. There are also no di ...
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Milk
Milk is a white liquid food produced by the mammary glands of mammals. It is the primary source of nutrition for young mammals (including breastfed human infants) before they are able to digestion, digest solid food. Immune factors and immune-modulating components in milk contribute to milk immunity. Early-lactation milk, which is called colostrum, contains antibody, antibodies that strengthen the immune system, and thus reduces the risk of many diseases. Milk contains many nutrients, including protein and lactose. As an agricultural product, dairy milk is Milking, collected from farm animals. In 2011, Dairy farming, dairy farms produced around of milk from 260 million dairy cows. India is the world's largest producer of milk and the leading exporter of skimmed milk powder, but it exports few other milk products. Because there is an ever-increasing demand for dairy products within India, it could eventually become a net importer of dairy products. New Zealand, Germany and the ...
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Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, Prescription drug, prescription and Over-the-counter drug, over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, Animal feed, animal foods & feed and Veterinary medicine, veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C), but the agency also enforces other laws, notably Section 361 of the Public Health Service Act, as well as associated regulations. Much of this regulatory-enforcement work is not d ...
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Mead Johnson
Mead Johnson & Company, LLC is an American company that is a leading manufacturer of infant formula, both domestically and globally, with its flagship product Enfamil. It operates as an independent subsidiary of Reckitt. The company dates back to a firm created by Edward Mead Johnson, one of the co-founders of Johnson & Johnson, who created his own business in 1895, which was renamed Mead Johnson & Company in 1905. The company was majority owned by Bristol-Myers Squibb after an acquisition in 1967, but was Corporate spin-off, spun-off in 2009 as an independent firm. Almost products were used by infants and children under 7, But Enfaschool which covers students from childhood to youth under 15 years. In the year end 31 December 2016, Mead Johnson reported net sales of $3,743 million. Fifty percent of those sales were generated in Asia, 17% in Latin America and 33% in North America/Europe. For the same time period, the company reported total assets of $4,088 million. In February 2 ...
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Tetrahydrobiopterin
Tetrahydrobiopterin (BH4, THB), also known as sapropterin (INN), is a cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin (5-hydroxytryptamine, 5-HT), melatonin, dopamine, norepinephrine (noradrenaline), epinephrine (adrenaline), and is a cofactor for the production of nitric oxide (NO) by the nitric oxide synthases. Chemically, its structure is that of a (dihydropteridine reductase) reduced pteridine derivative (quinonoid dihydrobiopterin). Medical use Tetrahydrobiopterin is available as a tablet for oral administration in the form of ''sapropterin dihydrochloride'' (BH4*2HCL). It was approved for use in the United States as a tablet in December 2007 and as a powder in December 2013. It was approved for use in the European Union in December 2008, Canada in April 2010, and Japan in July 2008. It is sold under the brand names Kuvan and Biopten. The typica ...
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Diet Therapy
Diet may refer to: Food * Diet (nutrition), the sum of the food consumed by an organism or group * Dieting, the deliberate selection of food to control body weight or nutrient intake ** Diet food, foods that aid in creating a diet for weight loss or gain * Healthy diet, the process of helping to maintain or improve overall health Politics *Diet (assembly), a formal deliberative assembly Current * National Diet, Japan's bicameral legislature, in its current form since 1947, composed of the House of Representatives and the House of Councillors * Landtag, a diet of states and provinces in Germany, Austria, South Tyrol in Italy, and the national parliament of Liechtenstein * Bundestag (''Deutscher Bundestag''), the lower house of Germany's Parliament, established in West Germany in 1949, and all of Germany in 1990 Historical * Diet of Finland, the legislative assembly of the Grand Duchy of Finland from 1809 to 1906 * Diet of Hungary, the legislative assembly of the Kingdom of Hung ...
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Infant Feeding
Infant nutrition is the description of the dietary needs of infants. A diet lacking essential calories, minerals, vitamins, or fluids is considered inadequate. Breast milk provides the best nutrition for these vital first months of growth when compared to infant formula. For example, breastfeeding aids in preventing anemia, obesity, and sudden infant death syndrome; and it promotes digestive health, immunity, intelligence, and dental development. The American Academy of Pediatrics recommends exclusively feeding an infant breast milk, or iron-fortified formula, for the first six months of life and continuing for one year or longer as desired by infant and mother. Infants are usually not introduced to solid foods until four to six months of age. Historically, breastfeeding infants was the only option for nutrition otherwise the infant would perish. Breastfeeding is rarely contraindicated, but is not recommended for mothers being treated for cancer, those with active tuberculosis, HIV, ...
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Milk Substitutes
A milk substitute is any substance that resembles milk and can be used in the same ways as milk. Such substances may be variously known as non-dairy beverage, nut milk, grain milk, legume milk, mock milk and alternative milk. For adults, milk substitutes take two forms: plant milks, which are liquids made from plants and may be home-made or commercially produced, and coffee creamers, synthetic products invented in the US in the 1900s specifically to replace dairy milk in coffee. For infants, breast milk can be substituted with infant formula based on cow's milk or plant based alternatives such as soybean. History Around the world, humans have traditionally consumed plant milks for hundreds, if not thousands, of years. In 2018, Tara McHugh in Food Technology Magazine wrote: "The word “milk” has been used since around 1200 AD to refer to plant juices." The article also said: "Of all the plant-based milks, coconut milk has the longest tradition of use. It originated in ...
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