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List Of Geneticists
This is a list of people who have made notable contributions to genetics. The growth and development of genetics represents the work of many people. This list of geneticists is therefore by no means complete. Contributors of great distinction to genetics are not yet on the list. __NOTOC__ A *Dagfinn Aarskog (1928–2014), Norwegian pediatrician and geneticist, described Aarskog–Scott syndrome * Jon Aase (born 1936), US dysmorphologist, described Aase syndrome, expert on fetal alcohol syndrome *John Abelson (born c. 1939), US biochemist, studies of machinery and mechanism of RNA splicing * Susan L. Ackerman, US neurogeneticist, genes controlling brain development and neuron survival *Jerry Adams (born 1940), US molecular biologist in Australia, hematopoietic genetics and cancer *Bruce Alberts (born 1938), US biochemist, phage worker, studied DNA replication and cell division * William Allan (1881–1943), US country doctor, pioneered human genetics * C. David Allis (born ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dagfinn Aarskog
Dagfinn Aarskog (10 December 1928 – 27 May 2014) was a Norwegian physician. Life He was born in Ålesund, Norway. He received his MD at the University of Bergen in 1956, and received a PhD in medicine in 1965. Aarskog was a specialist in pediatrics (paediatrics) from 1964 and in medical genetics from 1974. In the period 1964 to 1965, he worked as a research assistant at Johns Hopkins Hospital. He was appointed professor of pediatrics at the University of Bergen. In 1970, he first described the condition that has later been called the Aarskog–Scott syndrome. Aarskog held several international positions of trust, and was in 1992 appointed a Knight of the Order of St. Olav. References 1928 births 2014 deaths People from Ålesund Norwegian pediatricians Academic staff of the University of Bergen {{Norway-academic-bio-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chromatin
Chromatin is a complex of DNA and protein found in eukaryotic cells. The primary function is to package long DNA molecules into more compact, denser structures. This prevents the strands from becoming tangled and also plays important roles in reinforcing the DNA during cell division, preventing DNA damage, and regulating gene expression and DNA replication. During mitosis and meiosis, chromatin facilitates proper segregation of the chromosomes in anaphase; the characteristic shapes of chromosomes visible during this stage are the result of DNA being coiled into highly condensed chromatin. The primary protein components of chromatin are histones. An octamer of two sets of four histone cores (Histone H2A, Histone H2B, Histone H3, and Histone H4) bind to DNA and function as "anchors" around which the strands are wound.Maeshima, K., Ide, S., & Babokhov, M. (2019). Dynamic chromatin organization without the 30-nm fiber. ''Current opinion in cell biology, 58,'' 95–104. https://doi.o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nephritis
Nephritis is inflammation of the kidneys and may involve the glomeruli, tubules, or interstitial tissue surrounding the glomeruli and tubules. It is one of several different types of nephropathy. Types * Glomerulonephritis is inflammation of the glomeruli. Glomerulonephritis is often implied when using the term "nephritis" without qualification. * Interstitial nephritis (or tubulo-interstitial nephritis) is inflammation of the spaces between renal tubules. Causes Nephritis is often caused by infections, and toxins, but is most commonly caused by autoimmune disorders that affect the major organs like kidneys. * Pyelonephritis is inflammation that results from a urinary tract infection that reaches the renal pelvis of the kidney. * Lupus nephritis is inflammation of the kidney caused by systemic lupus erythematosus (SLE), a disease of the immune system. * Athletic nephritis is nephritis resulting from strenuous exercise. Bloody urine after strenuous exercise may also result from ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alport Syndrome
Alport syndrome is a genetic disorder affecting around 1 in 5,000-10,000 children, characterized by glomerulonephritis, end-stage kidney disease, and hearing loss. Alport syndrome can also affect the eyes, though the changes do not usually affect vision, except when changes to the lens occur in later life. Blood in urine is universal. Proteinuria is a feature as kidney disease progresses. The disorder was first identified in a British family by the physician Cecil A. Alport in 1927. Alport syndrome once also had the label hereditary nephritis, but this is misleading as there are many other causes of hereditary kidney disease and 'nephritis'. Alport syndrome is caused by an inherited defect in type IV collagen—a structural material that is needed for the normal function of different parts of the body. Since type IV collagen is found in the ears, eyes, and kidneys, this explains why Alport syndrome affects different seemingly unrelated parts of the body (ears, eyes, kidneys, etc. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cecil A
Cecil may refer to: People with the name * Cecil (given name), a given name (including a list of people and fictional characters with the name) * Cecil (surname), a surname (including a list of people with the name) Places Canada *Cecil, Alberta, Canada United States *Cecil, Alabama *Cecil, Georgia *Cecil, Ohio *Cecil, Oregon *Cecil, Pennsylvania *Cecil, West Virginia *Cecil, Wisconsin *Cecil Airport, in Jacksonville, Florida *Cecil County, Maryland Computing and technology *Cecil (programming language), prototype-based programming language *Computer Supported Learning, a learning management system by the University of Auckland, New Zealand Music *Cecil (British band), a band from Liverpool, active 1993-2000 *Cecil (Japanese band), a band from Kajigaya, Japan, active 2000-2006 Other uses *Cecil (lion), a famed lion killed in Zimbabwe in 2015 * Cecil (''Passions''), a minor character from the NBC soap opera ''Passions'' *Cecil (soil), the dominant red clay soil in the American ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nobel Prize
The Nobel Prizes ( ; sv, Nobelpriset ; no, Nobelprisen ) are five separate prizes that, according to Alfred Nobel's will of 1895, are awarded to "those who, during the preceding year, have conferred the greatest benefit to humankind." Alfred Nobel was a Swedish chemist, engineer, and industrialist most famously known for the invention of dynamite. He died in 1896. In his will, he bequeathed all of his "remaining realisable assets" to be used to establish five prizes which became known as "Nobel Prizes." Nobel Prizes were first awarded in 1901. Nobel Prizes are awarded in the fields of Physics, Chemistry, Physiology or Medicine, Literature, and Peace (Nobel characterized the Peace Prize as "to the person who has done the most or best to advance fellowship among nations, the abolition or reduction of standing armies, and the establishment and promotion of peace congresses"). In 1968, Sveriges Riksbank (Sweden's central bank) funded the establishment of the Prize in Economi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sidney Altman
Sidney Altman (May 7, 1939 – April 5, 2022) was a Canadian-American molecular biologist, who was the Sterling Professor of Molecular, Cellular, and Developmental Biology and Chemistry at Yale University. In 1989, he shared the Nobel Prize in Chemistry with Thomas R. Cech for their work on the catalytic properties of RNA. Family and education Altman was born on May 7, 1939, in Montreal, Quebec, Canada.Sidney Altman nobelprize.org His parents, Ray (Arlin), a textile worker, and Victor Altman, a grocer, were , each coming from |
Pharmacogenomics
Pharmacogenomics is the study of the role of the genome in drug response. Its name ('' pharmaco-'' + ''genomics'') reflects its combining of pharmacology and genomics. Pharmacogenomics analyzes how the genetic makeup of an individual affects their response to drugs. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating DNA mutations (including single-nucleotide polymorphisms, copy number variations, and insertions/deletions) with pharmacokinetic (drug absorption, distribution, metabolism, and elimination), pharmacodynamic (effects mediated through a drug's biological targets), and/or immunogenic endpoints. Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficiency with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that pharmaceutical drug treatments can deviate from what is dubbed as the "one-dos ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Russ Altman
Russ Biagio Altman is an American professor of bioengineering, genetics, medicine, and biomedical data science (and of computer science, by courtesy) and past chairman of the bioengineering department at Stanford University. Education Altman holds an A.B. from Harvard College in 1983, a Ph.D. in medical information sciences from Stanford in 1989 and M.D. from Stanford Medical School in 1990. After his internship at Stanford, he became board certified in 1991 in internal medicine and in clinical informatics in 2014. After a year of post-doctoral research, he joined the faculty as assistant professor in 1992. He became full professor in 2004, and was chair of the department of bioengineering from 2007 to June 2012. He currently is the Kenneth Fong Professor of Engineering at Stanford, and an advisor to the Chan Zuckerberg Biohub. As of 2018, Altman was a founding co-editor of the '' Annual Review of Biomedical Data Science''. Research and career His primary research interests are i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Frederick Alt
Frederick W. Alt is an American geneticist. He is a member of the Immunology section of the National Academy of Sciences and a Charles A. Janeway Professor of Pediatrics, and Professor of Genetics at Harvard Medical School. He is the Director of the Program in Cellular and Molecular Medicine at the Boston Children's Hospital. He is a Howard Hughes Medical Institute investigator, since 1987. Career Alt completed his undergraduate studies at Brandeis University, graduating in 1971. He then went on to earn a Ph.D. in Biology from Stanford University in 1977 while under the research direction of Robert Schimke. He performed his postdoctoral work in David Baltimore's laboratory at Massachusetts Institute of Technology (MIT). From 1982 to 1991 he was on the faculty at Columbia University and then moved to Harvard Medical School. Alt's research interest is in maintenance of genome stability in cells of the mammalian immunological system, particularly antigen receptor variable re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alström Syndrome
Alström syndrome (AS), also called Alström–Hallgren syndrome, is a very rare autosomal recessive genetic disorder characterised by childhood obesity and multiple organ dysfunction. Symptoms include early-onset type 2 diabetes, cone-rod dystrophy resulting in blindness, sensorineural hearing loss and dilated cardiomyopathy. Endocrine disorders typically also occur, such as hypergonadotrophic hypogonadism and hypothyroidism, as well as acanthosis nigricans resulting from hyperinsulinemia. Developmental delay is seen in almost half of people with Alström syndrome. It is caused by mutations in the gene ''ALMS1'', which is involved in the formation of cellular Cilium, cilia, making Alström syndrome a ciliopathy. At least 239 disease-causing mutations in ''ALMS1'' have been described . Alström syndrome is sometimes confused with Bardet–Biedl syndrome, another ciliopathy which has similar symptoms, but Bardet–Biedl syndrome tends to have later onset in its symptoms, includes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carl-Henry Alström
Carl-Henry Alström (3 May 1907 – 1993) was a Swedish psychiatrist who described a syndrome now named for him, Alström syndrome, a hereditary disorder that characteristically includes obesity in childhood, nerve deafness, and retinal degeneration (due to atypical retinitis pigmentosa Retinitis pigmentosa (RP) is a genetic disorder of the eyes that causes loss of vision. Symptoms include trouble seeing at night and decreasing peripheral vision (side and upper or lower visual field). As peripheral vision worsens, people may ...). External linksCarl-Henry Alströmbiographical sketch oWho Named It?site Alström Syndrome International 1907 births 1993 deaths Swedish psychiatrists 20th-century Swedish physicians {{psychiatrist-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
