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Linus Pauling Institute
The Linus Pauling Institute is a research institute located at the Oregon State University with a focus on health maintenance. The mission statement of the institute is to determine the functional roles of micronutrients and phytochemicals in promoting optimal health and to treat or prevent human disease, and to determine the role of oxidative stress and inflammation in health and disease. There are several major areas of research occurring at the institute, focused on many vitamins, minerals and other compounds found in the diet. The Linus Pauling Institute of Science and Medicine was founded in 1973 in Menlo Park, California by Linus Pauling and several colleagues under the name Institute of Orthomolecular Medicine. After Linus Pauling's death, it relocated to Oregon State University in 1996, and was renamed the Linus Pauling Institute. Several researchers from the original institute, including the assistant director of research, went on to form the Genetic Information Res ...
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Oregon State University
Oregon State University (OSU) is a public land-grant, research university in Corvallis, Oregon. OSU offers more than 200 undergraduate-degree programs along with a variety of graduate and doctoral degrees. It has the 10th largest engineering college in the nation for 2022. Undergraduate enrollment for all colleges combined averages close to 32,000, making it the state's largest university. Out-of-state students make up over one-quarter of undergraduates and an additional 5,500 students are engaged in graduate coursework through the university. Since its founding, over 272,000 students have graduated from OSU. It is classified among "Doctoral Universities – Very high research activity". Chartered as a land-grant university initially, OSU became one of the four inaugural members of the Sea Grant in 1971. It joined the Space Grant and Sun Grant research consortia in 1991 and 2003, respectively, making it the first public university and one of just four in total to attain me ...
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Micronutrients
Micronutrients are essential dietary elements required by organisms in varying quantities throughout life to orchestrate a range of physiological functions to maintain health. Micronutrient requirements differ between organisms; for example, humans and other animals require numerous vitamins and dietary minerals, whereas plants require specific minerals. For human nutrition, micronutrient requirements are in amounts generally less than 100 milligrams per day, whereas macronutrients are required in gram quantities daily. The minerals for humans and other animals include 13 elements that originate from Earth's soil and are not synthesized by living organisms, such as calcium and iron. Micronutrient requirements for animals also include vitamins, which are organic compounds required in microgram or milligram amounts. Since plants are the primary origin of nutrients for humans and animals, some micronutrients may be in low levels and deficiencies can occur when dietary intake is ins ...
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Phytochemicals
Phytochemicals are chemical compounds produced by plants, generally to help them resist fungi, bacteria and plant virus infections, and also consumption by insects and other animals. The name comes . Some phytochemicals have been used as poisons and others as traditional medicine. As a term, ''phytochemicals'' is generally used to describe plant compounds that are under research with unestablished effects on health, and are not scientifically defined as essential nutrients. Regulatory agencies governing food labeling in Europe and the United States have provided guidance for industry to limit or prevent health claims about phytochemicals on food product or nutrition labels. Definition Phytochemicals are chemicals of plant origin. Phytochemicals (from Greek ''phyto'', meaning "plant") are chemicals produced by plants through primary or secondary metabolism. They generally have biological activity in the plant host and play a role in plant growth or defense against competitors ...
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Oxidative Stress
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. Disturbances in the normal redox state of cells can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell, including proteins, lipids, and DNA. Oxidative stress from oxidative metabolism causes base damage, as well as strand breaks in DNA. Base damage is mostly indirect and caused by the reactive oxygen species generated, e.g., O2− ( superoxide radical), OH (hydroxyl radical) and H2O2 (hydrogen peroxide). Further, some reactive oxidative species act as cellular messengers in redox signaling. Thus, oxidative stress can cause disruptions in normal mechanisms of cellular signaling. In humans, oxidative stress is thought to be involved in the development of attention deficit hyperactivity disorder, cancer ...
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Inflammation
Inflammation (from la, inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators. The function of inflammation is to eliminate the initial cause of cell injury, clear out necrotic cells and tissues damaged from the original insult and the inflammatory process, and initiate tissue repair. The five cardinal signs are heat, pain, redness, swelling, and loss of function (Latin ''calor'', ''dolor'', ''rubor'', ''tumor'', and ''functio laesa''). Inflammation is a generic response, and therefore it is considered as a mechanism of innate immunity, as compared to adaptive immunity, which is specific for each pathogen. Too little inflammation could lead to progressive tissue destruction by the harmful stimulus (e.g. bacteria) and compromise the survival of the organism. In contrast, too much inflammation, in ...
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Menlo Park, California
Menlo Park is a city at the eastern edge of San Mateo County within the San Francisco Bay Area of California in the United States. It is bordered by San Francisco Bay on the north and east; East Palo Alto, Palo Alto, and Stanford to the south; and Atherton, North Fair Oaks, and Redwood City to the west. It is one of the most educated cities in California and the United States; nearly 70% of residents over 25 have earned a bachelor's degree or higher. It had 33,780 residents at the 2020 United States Census. It is home to the corporate headquarters of Meta, and is where Google, Roblox Corporation and Round Table Pizza were founded. Its train station holds the record as the oldest continually operating train station in California. Toponym "Menlo" is derived from Menlo (the anglicized spelling of Irish Gaelic 'Mionloch', meaning 'small lake') in County Galway, Ireland. The name "Menlo Park" was given to a ranch purchased by Irish settlers in honor of their home village i ...
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Linus Pauling
Linus Carl Pauling (; February 28, 1901August 19, 1994) was an American chemist, biochemist, chemical engineer, peace activist, author, and educator. He published more than 1,200 papers and books, of which about 850 dealt with scientific topics. ''New Scientist'' called him one of the 20 greatest scientists of all time, and as of 2000, he was rated the 16th most important scientist in history. For his scientific work, Pauling was awarded the Nobel Prize in Chemistry in 1954. For his peace activism, he was awarded the Nobel Peace Prize in 1962. He is one of five people to have won more than one Nobel Prize (the others being Marie Curie, John Bardeen, Frederick Sanger and Karl Barry Sharpless). Of these, he is the only person to have been awarded two unshared Nobel Prizes, and one of two people to be awarded Nobel Prizes in different fields, the other being Marie Curie. Pauling was one of the founders of the fields of quantum chemistry and molecular biology. His contributions to ...
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The America's Intelligence Wire
The America's Intelligence Wire is a daily general newswire service. The news service is owned and published by Financial Times, Ltd, which also operates companion newswire Europe Intelligence Wire. See also * Business and Company Resource Center, Gale Cengage Learning Gale is a global provider of research and digital learning resources. The company is based in Farmington Hills, Michigan, west of Detroit. It has been a division of Cengage since 2007. The company, formerly known as Gale Research and the Gale G ..., 2009 References News agencies based in the United States {{Journalism-stub ...
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Genetic Information Research Institute
The Genetic Information Research Institute (GIRI) is a non-profit institution that was founded in 1994 by Jerzy Jurka. The mission of the institute "is to understand biological processes which alter the genetic makeup of different organisms, as a basis for potential gene therapy and genome engineering techniques." The institute specializes in applying computer tools to analysis of DNA and protein sequence information. GIRI develops and maintains Repbase Update, a database of prototypic sequences representing repetitive DNA from different eukaryotic species, and Repbase Reports, an electronic journal established in 2001. Repetitive DNA is primarily derived from transposable elements (TEs), which include DNA transposons belonging to around 20 superfamilies and retrotransposons Retrotransposons (also called Class I transposable elements or transposons via RNA intermediates) are a type of genetic component that copy and paste themselves into different genomic locations ( transposon ...
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Mountain View, CA
Mountain View is a city in Santa Clara County, California, United States. Named for its views of the Santa Cruz Mountains, it has a population of 82,376. Mountain View was integral to the early history and growth of Silicon Valley, and is the location of many high technology companies. In 1956, William Shockley established Shockley Semiconductor Laboratory in Mountain View, the first company to develop silicon semiconductor devices in Silicon Valley. Today, Mountain View houses the headquarters of many of the world's largest technology companies, including Google and Alphabet Inc., Unicode Consortium, Intuit, NASA Ames research center, and major headquarter offices for Microsoft, Symantec, 23andMe, LinkedIn, Samsung, and Synopsys. History The Mexican land grant of Rancho Pastoria de las Borregas was given in 1842 by Alta California Governor Juan Alvarado to Francisco Estrada. This grant was later passed on to Mariano Castro, who sold half of the land to Martin Murphy Jr. ...
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Nutritionist
A nutritionist is a person who advises others on matters of food and nutrition and their impacts on health. Some people specialize in particular areas, such as sports nutrition, public health, or animal nutrition, among other disciplines. In many countries, a person can claim to be a nutritionist even without any training, education, or professional license, in contrast to a dietitian, who has a university degree, professional license, and certification for professional practice. Regulation of the title "nutritionist" The professional practice of being a ''dietitian'' (also spelled ''dietician'' in the US) is different from a ''nutritionist''. In many countries and jurisdictions, the title ''nutritionist'' is not subject to statutory professional regulation; thus, any person may self-title as a nutritionist or nutrition expert, even if self-taught and professionally uncertified. In the United Kingdom, Australia, parts of Canada, and most US states, a person self-titled as a ''nutr ...
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National Institutes Of Health
The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1880s and is now part of the United States Department of Health and Human Services. The majority of NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its own scientific research through the NIH Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research ins ...
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