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Lincoln Stein
Lincoln David Stein is a scientist and Professor in bioinformatics and computational biology at the Ontario Institute for Cancer Research. Education Stein completed a Doctor of Medicine at Harvard Medical School and a PhD in Cell Biology at Harvard University both in 1989 via the MD-PhD program. His thesis investigated gene cloning in '' Schistosoma mansoni''. Career From 1992-1997 he was a director of informatics at the Massachusetts Institute of Technology (MIT) Genome Centre, Whitehead Institute of Biomedical Research. From 1998 to 2004 he was an associate professor at Cold Spring Harbor Laboratory. He has been working at the Ontario Institute for Cancer Research since 2007. Research Stein's current research projects include Reactome, WormBase, BioPerl, Gramene, ENCODE, the Generic Model Organism Database, the Sequence Ontology and Cloud computing. Stein is also the original developer of CGI.pm and a contributor to mod_perl, both widely used in the Perl programming ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alfonso Valencia
Alfonso Valencia is a Spanish biologist, ICREA Professor, current director of the Life Sciences department at Barcelona Supercomputing Center. and of Spanish National Bioinformatics Institute (INB-ISCIII). From 2015-2018, he was President of the International Society for Computational Biology. His research is focused on the study of biomedical systems with computational biology and bioinformatics approaches. Education Valencia studied biology at the Complutense University of Madrid, training in population genetics and biophysics.. In 1987 he was a visiting scientist at the American Red Cross Laboratory. He received his PhD in molecular biology in 1988 from the Autonomous University of Madrid. From 1989 to 1994 he was a Postdoctoral Fellow in the laboratory of Chris Sander at the European Molecular Biology Laboratory (EMBL) in Heidelberg, studying the evolution of protein function using sequence- and structure-based approaches. The 1994 paper "Correlated mutations and residue con ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mod Perl
Mod, MOD or mods may refer to: Places * Modesto City–County Airport, Stanislaus County, California, US Arts, entertainment, and media Music * Mods (band), a Norwegian rock band * M.O.D. (Method of Destruction), a band from New York City, US * The Mods (band), a punk rock band from Toronto, Canada Other uses in arts, entertainment, and media * Manufactured on demand for CD, DVD distribution * ''Mod'' (film), 2011 * ''The Mods'' (film), 2014 * Mod (video games), unofficial modifications * , a Scottish Gaelic festival * Media-on-demand * ''MuchOnDemand'', a Canadian TV program Brands and enterprises * Mod Club Theatre, Toronto, Canada * MOD Pizza, US Organizations * MoD (UK), Ministry of Defence * Masters of Deception, a US hacker group * Ministry of defence * Ministry of Development (Brunei) Science and technology Computing and Internet * Mod, a module for Apache HTTP Server * Case modding of a computer * Forum moderator, of an online forum * Module file, a music f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cloud Computing
Cloud computing is the on-demand availability of computer system resources, especially data storage ( cloud storage) and computing power, without direct active management by the user. Large clouds often have functions distributed over multiple locations, each of which is a data center. Cloud computing relies on sharing of resources to achieve coherence and typically uses a "pay as you go" model, which can help in reducing capital expenses but may also lead to unexpected operating expenses for users. Value proposition Advocates of public and hybrid clouds claim that cloud computing allows companies to avoid or minimize up-front IT infrastructure costs. Proponents also claim that cloud computing allows enterprises to get their applications up and running faster, with improved manageability and less maintenance, and that it enables IT teams to more rapidly adjust resources to meet fluctuating and unpredictable demand, providing burst computing capability: high computi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sequence Ontology
The Sequence Ontology (SO) is an ontology In metaphysics, ontology is the philosophy, philosophical study of being, as well as related concepts such as existence, Becoming (philosophy), becoming, and reality. Ontology addresses questions like how entities are grouped into Category ... suitable for describing biological sequences. It is designed to make the naming of DNA sequence features and variants consistent and therefore machine-readable and searchable. References External links * {{cite web , url= http://www.sequenceontology.org/ , title= The Sequence Ontology , publisher= Sequence Ontology , access-date= 2011-09-19 Ontology (information science) Biological databases ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Generic Model Organism Database
The Generic Model Organism Database (GMOD) project provides biological research communities with a toolkit of open-source software components for visualizing, annotating, managing, and storing biological data. The GMOD project is funded by the United States National Institutes of Health, National Science Foundation and the USDA Agricultural Research Service. History The GMOD project was started in the early 2000s as a collaboration between several model organism databases (MODs) who shared a need to create similar software tools for processing data from sequencing projects. MODs, or organism-specific databases, describe genome and other information about important experimental organisms in the life sciences and capture the large volumes of data and information being generated by modern biology. Rather than each group designing their own software, four major MODs--FlyBase, Saccharomyces Genome Database, Mouse Genome Database, and WormBase—worked together to create application ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mark Bender Gerstein
Mark Bender Gerstein is an American scientist working in bioinformatics and Data Science. , he is co-director of the Yale Computational Biology and Bioinformatics program. Mark Gerstein is Albert L. Williams Professor of Biomedical Informatics, Professor of Molecular Biophysics & Biochemistry , Professor of Statistics & Data Science, and Professor of Computer Science at Yale University. In 2018, Gerstein was named co-director of thYale Center for Biomedical Data Science. Education After graduating from Harvard College summa cum laude with a Bachelor of Arts in physics in 1989, Gerstein did a PhD co-supervised by Ruth Lynden-Bell at the University of Cambridge and Cyrus Chothia at the Laboratory of Molecular Biology on conformational change in proteins, graduating in 1993. He then went on to postdoctoral research in bioinformatics at Stanford University from 1993 to 1996 supervised by Nobel-laureate Michael Levitt. Research Gerstein does research in the field of bi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ENCODE
The Encyclopedia of DNA Elements (ENCODE) is a public research project which aims to identify functional elements in the human genome. ENCODE also supports further biomedical research by "generating community resources of genomics data, software, tools and methods for genomics data analysis, and products resulting from data analyses and interpretations." The current phase of ENCODE (2016-2019) is adding depth to its resources by growing the number of cell types, data types, assays and now includes support for examination of the mouse genome. History ENCODE was launched by the US National Human Genome Research Institute (NHGRI) in September 2003. Intended as a follow-up to the Human Genome Project, the ENCODE project aims to identify all functional elements in the human genome. The project involves a worldwide consortium of research groups, and data generated from this project can be accessed through public databases. The initial release of ENCODE was in 2013 and since has be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
BioPerl
BioPerl is a collection of Perl modules that facilitate the development of Perl scripts for bioinformatics applications. It has played an integral role in the Human Genome Project. Background BioPerl is an active open source software project supported by the Open Bioinformatics Foundation. The first set of Perl codes of BioPerl was created by Tim Hubbard and Jong Bhak at MRC Centre Cambridge, where the first genome sequencing was carried out by Fred Sanger. MRC Centre was one of the hubs and birth places of modern bioinformatics as it had a large quantity of DNA sequences and 3D protein structures. Hubbard was using the th_lib.pl Perl library, which contained many useful Perl subroutines for bioinformatics. Bhak, Hubbard's first PhD student, created jong_lib.pl. Bhak merged the two Perl subroutine libraries into Bio.pl. The name BioPerl was coined jointly by Bhak and Steven Brenner at the Centre for Protein Engineering (CPE). In 1995, Brenner organized a BioPerl session at the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Reactome
Reactome is a free online database of biological pathways. There are several Reactomes that concentrate on specific organisms, the largest of these is focused on human biology, the following description concentrates on the human Reactome. It is authored by biologists, in collaboration with Reactome editorial staff. The content is cross-referenced to many bioinformatics databases. The rationale behind Reactome is to visually represent biological pathways in full mechanistic detail, while making the source data available in a computationally accessible format. The website can be used to browse pathways and submit data to a suite of data analysis tools. The underlying data is fully downloadable in a number of standard formats including PDF, SBML and BioPAX. Pathway diagrams use a Systems Biology Graphical Notation (SBGN)-based style. The core unit of the Reactome data model is the reaction. Entities (nucleic acids, proteins, complexes and small molecules) participating in reactions fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Associate Professor
Associate professor is an academic title with two principal meanings: in the North American system and that of the ''Commonwealth system''. Overview In the '' North American system'', used in the United States and many other countries, it is a position between assistant professor and a full professorship. In this system an associate professorship is typically the first promotion obtained after gaining a faculty position, and in the United States it is usually connected to tenure. In the ''Commonwealth system'' (Canada included), the title associate professor is traditionally used in place of reader in certain countries.UK Academic Job Titles Explained academicpositions.com Like the reader title it ranks above senior lecturer – which corresponds to asso ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
