Karl J. Friston
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Karl J. Friston
Karl John Friston FRS FMedSci FRSB (born 12 July 1959) is a British neuroscientist and theoretician at University College London. He is an authority on brain imaging and theoretical neuroscience, especially the use of physics-inspired statistical methods to model neuroimaging data and other random dynamical systems. He is a key architect of the free energy principle and active inference. In imaging neuroscience he is best known for statistical parametric mapping and dynamic causal modelling. In October 2022, he joined VERSES Inc, a California-based cognitive computing company focusing on artificial intelligence designed using the principles of active inference, as Chief Scientist. Friston is one of the most highly cited scientists of all time and in 2016 was ranked No. 1 by Semantic Scholar in the list of top 10 most influential neuroscientists. Education Karl Friston attended the Ellesmere Port Grammar School, later renamed Whitby Comprehensive, from 1970–1977. ...
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York
York is a cathedral city with Roman origins, sited at the confluence of the rivers Ouse and Foss in North Yorkshire, England. It is the historic county town of Yorkshire. The city has many historic buildings and other structures, such as a minster, castle, and city walls. It is the largest settlement and the administrative centre of the wider City of York district. The city was founded under the name of Eboracum in 71 AD. It then became the capital of the Roman province of Britannia Inferior, and later of the kingdoms of Deira, Northumbria, and Scandinavian York. In the Middle Ages, it became the northern England ecclesiastical province's centre, and grew as a wool-trading centre. In the 19th century, it became a major railway network hub and confectionery manufacturing centre. During the Second World War, part of the Baedeker Blitz bombed the city; it was less affected by the war than other northern cities, with several historic buildings being gutted and restore ...
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Fellow Of The Royal Society Of Biology
Fellowship of the Royal Society of Biology (FRSB), previously Fellowship of the Society of Biology (FSB), is an award and fellowship granted to individuals that the Royal Society of Biology has adjudged to have made a "prominent contribution to the advancement of the biological sciences, and has gained no less than five years of experience in a position of senior responsibility". Fellowship Fellows are entitled to use the post-nominal letters FRSB. examples of fellows include David Attenborough, Martin Hume Johnson, Jasmin Fisher and Nancy Rothwell Dame Nancy Jane Rothwell (born 2 October 1955) is a British physiologist. She has served as president and vice-chancellor of the University of Manchester since July 2010, having served as Deputy President and Deputy Vice-Chancellor until Januar .... See the : Fellows of the Royal Society of Biology for more examples. References {{Reflist Royal Society of Biology Academic awards * ...
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Gerald Edelman
Gerald Maurice Edelman (; July 1, 1929 – May 17, 2014) was an American biologist who shared the 1972 Nobel Prize in Physiology or Medicine for work with Rodney Robert Porter on the immune system. Edelman's Nobel Prize-winning research concerned discovery of the structure of antibody molecules.Structural differences among antibodies of different specificities
by G. M. Edelman, B. Benacerraf, Z. Ovary and M. D. Poulik in ''Proc Natl Acad Sci U S A'' (1961) volume 47, pages 1751-1758.
In interviews, he has said that the way the components of the immune system evolve over the life of the individual is analogous to the way the components of the brain evolve in a lifetime. There is a continuity in this way between his work on the immune system, for ...
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Random Field
In physics and mathematics, a random field is a random function over an arbitrary domain (usually a multi-dimensional space such as \mathbb^n). That is, it is a function f(x) that takes on a random value at each point x \in \mathbb^n(or some other domain). It is also sometimes thought of as a synonym for a stochastic process with some restriction on its index set. That is, by modern definitions, a random field is a generalization of a stochastic process where the underlying parameter need no longer be real or integer valued "time" but can instead take values that are multidimensional vectors or points on some manifold. Formal definition Given a probability space (\Omega, \mathcal, P), an ''X''-valued random field is a collection of ''X''-valued random variables indexed by elements in a topological space ''T''. That is, a random field ''F'' is a collection : \ where each F_t is an ''X''-valued random variable. Examples In its discrete version, a random field is a list of rando ...
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General Linear Model
The general linear model or general multivariate regression model is a compact way of simultaneously writing several multiple linear regression models. In that sense it is not a separate statistical linear model. The various multiple linear regression models may be compactly written as : \mathbf = \mathbf\mathbf + \mathbf, where Y is a matrix with series of multivariate measurements (each column being a set of measurements on one of the dependent variables), X is a matrix of observations on independent variables that might be a design matrix (each column being a set of observations on one of the independent variables), B is a matrix containing parameters that are usually to be estimated and U is a matrix containing errors (noise). The errors are usually assumed to be uncorrelated across measurements, and follow a multivariate normal distribution. If the errors do not follow a multivariate normal distribution, generalized linear models may be used to relax assumptions about Y and ...
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National Hospital For Neurology And Neurosurgery
The National Hospital for Neurology and Neurosurgery (informally the National Hospital or Queen Square) is a neurological hospital in Queen Square, London. It is part of the University College London Hospitals NHS Foundation Trust. It was the first hospital to be established in England dedicated exclusively to treating the diseases of the nervous system. It is closely associated with University College London (UCL) and in partnership with the UCL Institute of Neurology, which occupies the same site, is a major centre for neuroscience research. History The hospital was founded by Johanna Chandler as the National Hospital for the Paralysed and Epileptic at Queen Square in 1859. The hospital was completely rebuilt in the early 1880s: the East Wing was re-opened by Princess Helena in 1881 and the West Wing was re-opened by the Prince of Wales in 1885. In 1904, it adopted the name National Hospital for the Relief and Cure of the Paralysed and Epileptic. The hospital served as a s ...
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King's College Hospital
King's College Hospital is a major teaching hospital and major trauma centre in Denmark Hill, Camberwell in the London Borough of Lambeth, referred to locally and by staff simply as "King's" or abbreviated internally to "KCH". It is managed by King's College Hospital NHS Foundation Trust. It serves an inner city population of 700,000 in the London boroughs of Southwark and Lambeth, but also serves as a tertiary referral centre in certain specialties to millions of people in southern England. It is a large teaching hospital and is, with Guy's Hospital and St. Thomas' Hospital, the location of King's College London School of Medicine and one of the institutions that comprise the King's Health Partners, an academic health science centre. The chief executive is Dr Clive Kay. History Early history King's was originally opened in 1840 in the disused St Clement Danes workhouse in Portugal Street close to Lincoln's Inn Fields and King's College London itself. It was used as a trai ...
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University Of Cambridge
, mottoeng = Literal: From here, light and sacred draughts. Non literal: From this place, we gain enlightenment and precious knowledge. , established = , other_name = The Chancellor, Masters and Scholars of the University of Cambridge , type = Public research university , endowment = £7.121 billion (including colleges) , budget = £2.308 billion (excluding colleges) , chancellor = The Lord Sainsbury of Turville , vice_chancellor = Anthony Freeling , students = 24,450 (2020) , undergrad = 12,850 (2020) , postgrad = 11,600 (2020) , city = Cambridge , country = England , campus_type = , sporting_affiliations = The Sporting Blue , colours = Cambridge Blue , website = , logo = University of Cambridge logo ...
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Natural Sciences (Cambridge)
The Natural Sciences Tripos (NST) is the framework within which most of the science at the University of Cambridge is taught. The tripos includes a wide range of Natural Sciences from physics, astronomy, and geoscience, to chemistry and biology, which are taught alongside the history and philosophy of science. The tripos covers several courses which form the University of Cambridge system of Tripos. It is known for its broad range of study in the first year, in which students cannot study just one discipline, but instead must choose three courses in different areas of the natural sciences and one in mathematics. As is traditional at Cambridge, the degree awarded after Part II (three years of study) is a Bachelor of Arts (BA). A Master of Natural Sciences degree (MSci) is available to those who take the optional Part III (one further year). It was started in the 19th Century. Teaching Teaching is carried out by 16 different departments. Subjects offered in Part IA in 2019 are Biol ...
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Semantic Scholar
Semantic Scholar is an artificial intelligence–powered research tool for scientific literature developed at the Allen Institute for AI and publicly released in November 2015. It uses advances in natural language processing to provide summaries for scholarly papers. The Semantic Scholar team is actively researching the use of artificial-intelligence in natural language processing, machine learning, Human-Computer interaction, and information retrieval. Semantic Scholar began as a database surrounding the topics of computer science, geoscience, and neuroscience. However, in 2017 the system began including biomedical literature in its corpus. As of September 2022, they now include over 200 million publications from all fields of science. Technology Semantic Scholar provides a one-sentence summary of scientific literature. One of its aims was to address the challenge of reading numerous titles and lengthy abstracts on mobile devices. It also seeks to ensure that the three mill ...
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Statistical Parametric Mapping
Statistical parametric mapping (SPM) is a statistical technique for examining differences in brain activity recorded during functional neuroimaging experiments. It was created by Karl Friston. It may alternatively refer to software created by the Wellcome Department of Imaging Neuroscience at University College London to carry out such analyses. Approach Unit of measurement Functional neuroimaging is one type of 'brain scanning'. It involves the measurement of brain activity. The measurement technique depends on the imaging technology (e.g., fMRI and PET). The scanner produces a 'map' of the area that is represented as voxels. Each voxel represents the activity of a specific volume in three-dimensional space. The exact size of a voxel varies depending on the technology. fMRI voxels typically represent a volume of 27 mm3 in an equilateral cuboid. Experimental design Researchers examine brain activity linked to a specific mental process or processes. One approach involves aski ...
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Philosophical Transactions Of The Royal Society B
''Philosophical Transactions of the Royal Society B: Biological Sciences'' is a biweekly peer-reviewed scientific journal published by the Royal Society. The editor-in-chief is John Pickett (Cardiff University). Overview Each issue covers a specific area of the biological sciences. Each issue aims to create an original and authoritative synthesis, often bridging traditional disciplines, which showcases current developments and provides a foundation for future research, applications and policy decisions. Each issue is edited by one or more expert guest editors. The themes fall into one of four general categories: * Cell and Development * Health and Disease * Environment and Evolution * Neuroscience and Cognition All articles become freely accessible one year after their publication date. History ''Philosophical Transactions of the Royal Society'' was established in 1665 by the Royal Society and is the oldest scientific journal in the English-speaking world. Henry Oldenburg ...
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