Kringles
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Kringles
Kringle (, ) is a Northern European pastry, a variety of pretzel. Pretzels were introduced by Roman Catholic monks in the 13th century in Denmark, and from there they spread throughout Scandinavia and evolved into several kinds of sweet, salty or filled pastries, all in the shape of kringle. In Danish and Norwegian, the word is ''kringle'', plural ''kringler''; et, kringel, plural ''kringlid''; lv, kliņģeris, plural ''kliņģeri''; sv, kringla, plural ''kringlor''; fi, rinkeli; german: Kringel and Icelandic: ''kringla''. The word originates from the Old Norse ''kringla'', meaning ring or circle. In the Netherlands, a particular type of sweet kringle is well known under the Dutch name ''krakeling''. The shape of the kringle has given name to a similarly entangled feature found in some proteins, the so-called Kringle domain. Scandinavia In Denmark, ''kringle'' denotes the pretzel-like knotted shape rather than the pretzel pastry type. Kringler may be made from ...
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Kringle Domain
Kringle Domains are autonomous protein domains that fold into large loops stabilized by 3 disulfide linkages. These are important in protein–protein interactions with blood coagulation factors. Their name refers to the Kringle, a Scandinavian pastry which they somewhat resemble. Kringle domains have been found in plasminogen, hepatocyte growth factors, prothrombin, and apolipoprotein(a). Kringles are found throughout the blood clotting and fibrinolytic proteins. Kringle domains are believed to play a role in binding mediators (e.g., membranes, other proteins or phospholipids), and in the regulation of proteolytic activity. Kringle domains are characterised by a triple loop, 3-disulfide bridge structure, whose conformation is defined by a number of hydrogen bonds and small pieces of anti-parallel beta-sheet. They are found in a varying number of copies in some plasma proteins including prothrombin and urokinase-type plasminogen activator, which are serine proteases belonging ...
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Scandinavia
Scandinavia; Sámi languages: /. ( ) is a subregion#Europe, subregion in Northern Europe, with strong historical, cultural, and linguistic ties between its constituent peoples. In English usage, ''Scandinavia'' most commonly refers to Denmark, Norway, and Sweden. It can sometimes also refer more narrowly to the Scandinavian Peninsula (which excludes Denmark but includes part of Finland), or more broadly to include all of Finland, Iceland, and the Faroe Islands. The geography of the region is varied, from the Norwegian fjords in the west and Scandinavian mountains covering parts of Norway and Sweden, to the low and flat areas of Denmark in the south, as well as archipelagos and lakes in the east. Most of the population in the region live in the more temperate southern regions, with the northern parts having long, cold, winters. The region became notable during the Viking Age, when Scandinavian peoples participated in large scale raiding, conquest, colonization and trading mostl ...
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Yeast
Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom. The first yeast originated hundreds of millions of years ago, and at least 1,500 species are currently recognized. They are estimated to constitute 1% of all described fungal species. Yeasts are unicellular organisms that evolved from multicellular ancestors, with some species having the ability to develop multicellular characteristics by forming strings of connected budding cells known as pseudohyphae or false hyphae. Yeast sizes vary greatly, depending on species and environment, typically measuring 3–4  µm in diameter, although some yeasts can grow to 40 µm in size. Most yeasts reproduce asexually by mitosis, and many do so by the asymmetric division process known as budding. With their single-celled growth habit, yeasts can be contrasted with molds, which grow hyphae. Fungal species that can take both forms (depending on temperature or other conditions) are ca ...
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Solvang, California
Solvang (; ) is a city in Santa Barbara County, California. It is located in the Santa Ynez Valley. The population was 6,126 at the 2020 census, up from 5,245 at the 2010 census. Solvang was founded in 1911 and incorporated as a city on May 1, 1985. Solvang is often dubbed "The Danish Capital of America". Solvang's origins date back to 1804, when Mission Santa Inés was founded by the Spanish under Esteban Tápis. A small community grew up around the mission called Santa Inés during the Mexican period, but it was largely abandoned after the American Conquest of California. In 1911, a new settlement was founded around the mission by a group of Danish-Americans who purchased of the surrounding Rancho San Carlos de Jonata, to establish a Danish community far from Midwestern winters. The community took on its distinctive Danish-themed architecture beginning in 1947 and has since become a prominent tourist destination. Though only about 10% of residents in the 21st century are ...
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Redmond, Washington
Redmond is a city in King County, Washington, United States, located east of Seattle. The population was 73,256 at the 2020 census, up from 54,144 in 2010. Redmond is best known as the home of Microsoft and Nintendo of America. With an annual bike race on city streets and the state's only velodrome, Redmond is also known as the "Bicycle Capital of the Northwest". History Native Americans have lived in the Redmond area for about 10,000 years, based on artifacts discovered at the Redmond Town Center archaeological site and Marymoor Prehistoric Indian Site. The first European settlers arrived in the 1870s. Luke McRedmond filed a Homestead Act claim for land next to the Sammamish Slough on September 9, 1870, and the following year Warren Perrigo took up land adjacent to him. The rivers and streams had so many salmon that the settlement was initially named Salmonberg. More settlers came, and with the establishment of the first post office in 1881, the name of the community w ...
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Seattle
Seattle ( ) is a seaport city on the West Coast of the United States. It is the seat of King County, Washington. With a 2020 population of 737,015, it is the largest city in both the state of Washington and the Pacific Northwest region of North America. The Seattle metropolitan area's population is 4.02 million, making it the 15th-largest in the United States. Its growth rate of 21.1% between 2010 and 2020 makes it one of the nation's fastest-growing large cities. Seattle is situated on an isthmus between Puget Sound (an inlet of the Pacific Ocean) and Lake Washington. It is the northernmost major city in the United States, located about south of the Canadian border. A major gateway for trade with East Asia, Seattle is the fourth-largest port in North America in terms of container handling . The Seattle area was inhabited by Native Americans for at least 4,000 years before the first permanent European settlers. Arthur A. Denny and his group of travelers, subsequ ...
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Ballard, Seattle
Ballard is a neighborhood in the northwestern area of Seattle, Washington, United States. Formerly an independent city, the City of Seattle's official boundaries define it as bounded to the north by Crown Hill (N.W. 85th Street), to the east by Greenwood, Phinney Ridge and Fremont (along 3rd Avenue N.W.), to the south by the Lake Washington Ship Canal, and to the west by Puget Sound's Shilshole Bay. Other neighborhood or district boundaries existed in the past; these are recognized by various Seattle City Departments, commercial or social organizations, and other Federal, State, and local government agencies. Landmarks of Ballard include the Ballard Locks, the National Nordic Museum, the Shilshole Bay Marina, and Golden Gardens Park. The neighborhood's main thoroughfares running north–south are Seaview, 32nd, 24th, Leary, 15th, and 8th Avenues N.W. East–west traffic is carried by N.W. Leary Way and N.W. 85th, 80th, 65th, and Market Streets. The Ballard Bridge carries 15t ...
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Middleton, Wisconsin
Middleton is a city in Dane County, Wisconsin, United States, and a suburb of the state capital, Madison. Middleton's motto is "The Good Neighbor City." The population was 21,827 at the 2020 census. In 2007, Middleton was chosen as the best place to live by ''CNN Money'' magazine. ''CNN'' ''Money'' magazine praised Middleton's "small-town charm, booming economy, extensive parks and bike trails." In 2009, Middleton was placed 4th, and 8th in 2011, on ''CNN Money'' magazine's list of best small towns to live in the United States. In 2021, Middleton was chosen as the "Best Suburbs to Raise a Family in Dane County" by ranking and review website ''Niche''. History The first settlers were mostly of English descent, and they came to Middleton in the 1840s. It was called Peatville for the large quantities of peat extracted from its soil. The village was renamed Middleton when it was separated from the town of Madison in 1848. Many German settlers arrived to Middleton in the 1850s, and a ...
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Wisconsin
Wisconsin () is a state in the upper Midwestern United States. Wisconsin is the 25th-largest state by total area and the 20th-most populous. It is bordered by Minnesota to the west, Iowa to the southwest, Illinois to the south, Lake Michigan to the east, Michigan to the northeast, and Lake Superior to the north. The bulk of Wisconsin's population live in areas situated along the shores of Lake Michigan. The largest city, Milwaukee, anchors its largest metropolitan area, followed by Green Bay and Kenosha, the third- and fourth-most-populated Wisconsin cities respectively. The state capital, Madison, is currently the second-most-populated and fastest-growing city in the state. Wisconsin is divided into 72 counties and as of the 2020 census had a population of nearly 5.9 million. Wisconsin's geography is diverse, having been greatly impacted by glaciers during the Ice Age with the exception of the Driftless Area. The Northern Highland and Western Upland along wi ...
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Racine, Wisconsin
Racine ( ) is a city in and the county seat of Racine County, Wisconsin, United States. It is located on the shore of Lake Michigan at the mouth of the Root River. Racine is situated 22 miles (35 km) south of Milwaukee and approximately 60 miles (100 km) north of Chicago. It is the principal city of the US Census Bureau's Racine metropolitan area (consisting only of Racine County). The Racine metropolitan area is, in turn, counted as part of the Milwaukee combined statistical area. As of the 2020 U.S. Census, the city had a population of 77,816, making it the 5th largest city in Wisconsin. In January 2017, it was rated "the most affordable place to live in the world" by the Demographia International Housing Affordability survey. Racine is the headquarters of a number of industries, including J. I. Case heavy equipment, S. C. Johnson & Son cleaning and chemical products, Dremel Corporation, Reliance Controls Corporation time controls and transfer switches, Twin Disc, ...
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United States
The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territories, nine Minor Outlying Islands, and 326 Indian reservations. The United States is also in free association with three Pacific Island sovereign states: the Federated States of Micronesia, the Marshall Islands, and the Republic of Palau. It is the world's third-largest country by both land and total area. It shares land borders with Canada to its north and with Mexico to its south and has maritime borders with the Bahamas, Cuba, Russia, and other nations. With a population of over 333 million, it is the most populous country in the Americas and the third most populous in the world. The national capital of the United States is Washington, D.C. and its most populous city and principal financial center is New York City. Paleo-Americ ...
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Kringle
Kringle (, ) is a Northern European pastry, a variety of pretzel. Pretzels were introduced by Roman Catholic monks in the 13th century in Denmark, and from there they spread throughout Scandinavia and evolved into several kinds of sweet, salty or filled pastries, all in the shape of kringle. In Danish and Norwegian, the word is ''kringle'', plural ''kringler''; et, kringel, plural ''kringlid''; lv, kliņģeris, plural ''kliņģeri''; sv, kringla, plural ''kringlor''; fi, rinkeli; german: Kringel and Icelandic: ''kringla''. The word originates from the Old Norse ''kringla'', meaning ring or circle. In the Netherlands, a particular type of sweet kringle is well known under the Dutch name ''krakeling''. The shape of the kringle has given name to a similarly entangled feature found in some proteins, the so-called Kringle domain. Scandinavia In Denmark, ''kringle'' denotes the pretzel-like knotted shape rather than the pretzel pastry type. Kringler may be made from puff ...
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