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Kevin Karplus
Kevin Karplus is a professor emeritus at University of California, Santa Cruz, currently in the Biomolecular Engineering Department. He is probably best known for work he did as a computer science graduate student at Stanford University on the Karplus-Strong string synthesis algorithm. He taught VLSI design and computer engineering for several years, helping create the Computer Engineering Department at University of California, Santa Cruz. He made some contributions to VLSI CAD, particularly to logic minimization, where he invented the if-then-else DAG (a generalization of the binary decision diagram) and a canonical form for it, before switching to protein structure prediction and bioinformatics in 1995. He has participated in CASP (Critical Assessment of Techniques for Protein Structure Prediction) since CASP2 in 1996, and has been invited to present papers at CASP2, 3, 4, 5, 6, 7, and 8. He served on thBoard of Directorsfor the International Society for Computational Biolog ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Computer Science
Computer science is the study of computation, automation, and information. Computer science spans theoretical disciplines (such as algorithms, theory of computation, information theory, and automation) to Applied science, practical disciplines (including the design and implementation of Computer architecture, hardware and Computer programming, software). Computer science is generally considered an area of research, academic research and distinct from computer programming. Algorithms and data structures are central to computer science. The theory of computation concerns abstract models of computation and general classes of computational problem, problems that can be solved using them. The fields of cryptography and computer security involve studying the means for secure communication and for preventing Vulnerability (computing), security vulnerabilities. Computer graphics (computer science), Computer graphics and computational geometry address the generation of images. Progr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Logic Minimization
Logic optimization is a process of finding an equivalent representation of the specified logic circuit under one or more specified constraints. This process is a part of a logic synthesis applied in digital electronics and integrated circuit design. Generally, the circuit is constrained to a minimum chip area meeting a predefined response delay. The goal of logic optimization of a given circuit is to obtain the smallest logic circuit that evaluates to the same values as the original one. The smaller circuit with the same function is cheaper, takes less space, consumes less power, have shorter latency, and minimizes risks of unexpected cross-talk, hazard of delayed signal processing, and other issues present at the nano-scale level of metallic structures on an integrated circuit. In terms of Boolean algebra, the optimization of a complex boolean expression is a process of finding a simpler one, which would upon evaluation ultimately produce the same results as the original on ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stanford University Alumni
Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is considered among the most prestigious universities in the world. Stanford was founded in 1885 by Leland and Jane Stanford in memory of their only child, Leland Stanford Jr., who had died of typhoid fever at age 15 the previous year. Leland Stanford was a U.S. senator and former governor of California who made his fortune as a railroad tycoon. The school admitted its first students on October 1, 1891, as a coeducational and non-denominational institution. Stanford University struggled financially after the death of Leland Stanford in 1893 and again after much of the campus was damaged by the 1906 San Francisco earthquake. Following World War II, provost of Stanford Frederick Terman inspired and supported faculty and graduates' entrepreneuriali ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of California, Santa Cruz Faculty
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States, the designation is reserved for colleges that have a graduate school. The word ''university'' is derived from the Latin ''universitas magistrorum et scholarium'', which roughly means "community of teachers and scholars". The first universities were created in Europe by Catholic Church monks. The University of Bologna (''Università di Bologna''), founded in 1088, is the first university in the sense of: *Being a high degree-awarding institute. *Having independence from the ecclesiastic schools, although conducted by both clergy and non-clergy. *Using the word ''universitas'' (which was coined at its foundation). *Issuing secular and non-secular degrees: grammar, rhetoric, logic, theology, canon law, notarial law.Hunt Janin: "The university i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Santa Cruz County Regional Transportation Commission
Santa Claus, also known as Father Christmas, Saint Nicholas, Saint Nick, Kris Kringle, or simply Santa, is a legendary figure originating in Western Christian culture who is said to bring children gifts during the late evening and overnight hours on Christmas Eve of toys and candy or coal or nothing, depending on whether they are "naughty or nice". In the legend, he accomplishes this with the aid of Christmas elves, who make the toys in his workshop, often said to be at the North Pole, and flying reindeer who pull his sleigh through the air. The modern figure of Santa is based on folklore traditions surrounding Saint Nicholas, the English figure of Father Christmas and the Dutch figure of ''Sinterklaas''. Santa is generally depicted as a portly, jolly, white-bearded man, often with spectacles, wearing a red coat with white fur collar and cuffs, white-fur-cuffed red trousers, red hat with white fur, and black leather belt and boots, carrying a bag full of gifts for child ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
League Of American Bicyclists
The League of American Bicyclists (LAB), officially the League of American Wheelmen, is a membership organization that promotes cycling for fun, fitness and transportation through advocacy and education. A Section 501(c)(3) nonprofit organization, the League is one of the largest membership organizations of cyclists in the United States. History Founded in Newport, Rhode Island, on May 30, 1880, as the League of American Wheelmen by Kirk Munroe and Charles E. Pratt, it soon became the leading national membership organization for cyclists in the United States. The organization's first officers were Charles E. Pratt as president, T.K. Longstreet as vice president, O.S. Parsons as corresponding secretary, J.F. Furrell as recording secretary, and H.L. Willoughby as treasurer."The American Wheelmen". ''The Washington Post''. June 1, 1880. p. 1. The board of directors consisted of two from each state having regularly organization clubs. Pratt served two terms as the organization's fi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Society For Computational Biology
The International Society for Computational Biology (ISCB) is a scholarly society for researchers in computational biology and bioinformatics. The society was founded in 1997 to provide a stable financial home for the Intelligent Systems for Molecular Biology (ISMB) conference and has grown to become a larger society working towards advancing understanding of living systems through computation and for communicating scientific advances worldwide. In addition to ISMB, the society also organizes a growing number of smaller, more regionally or topically focused conferences and presents a number of annual scientific achievement awards, including the Overton Prize and the ISCB Senior Scientist Awards. Overview Society membership reflects commitment toward the advancement of computational biology. The ISCB is an international non-profit organization whose members come from the global bioinformatics and computational biology communities. The ISCB serves its global membership by providing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bioinformatics
Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combines biology, chemistry, physics, computer science, information engineering, mathematics and statistics to analyze and interpret the biological data. Bioinformatics has been used for '' in silico'' analyses of biological queries using computational and statistical techniques. Bioinformatics includes biological studies that use computer programming as part of their methodology, as well as specific analysis "pipelines" that are repeatedly used, particularly in the field of genomics. Common uses of bioinformatics include the identification of candidates genes and single nucleotide polymorphisms (SNPs). Often, such identification is made with the aim to better understand the genetic basis of disease, unique adaptations, desirable properties (e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Binary Decision Diagram
In computer science, a binary decision diagram (BDD) or branching program is a data structure that is used to represent a Boolean function. On a more abstract level, BDDs can be considered as a compressed representation of sets or relations. Unlike other compressed representations, operations are performed directly on the compressed representation, i.e. without decompression. Similar data structures include negation normal form (NNF), Zhegalkin polynomials, and propositional directed acyclic graphs (PDAG). Definition A Boolean function can be represented as a rooted, directed, acyclic graph, which consists of several (decision) nodes and two terminal nodes. The two terminal nodes are labeled 0 (FALSE) and 1 (TRUE). Each (decision) node u is labeled by a Boolean variable x_i and has two child nodes called low child and high child. The edge from node u to a low (or high) child represents an assignment of the value FALSE (or TRUE, respectively) to variable x_i. Such a BDD is ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Computer-aided Design
Computer-aided design (CAD) is the use of computers (or ) to aid in the creation, modification, analysis, or optimization of a design. This software is used to increase the productivity of the designer, improve the quality of design, improve communications through documentation, and to create a database for manufacturing. Designs made through CAD software are helpful in protecting products and inventions when used in patent applications. CAD output is often in the form of electronic files for print, machining, or other manufacturing operations. The terms computer-aided drafting (CAD) and computer aided design and drafting (CADD) are also used. Its use in designing electronic systems is known as '' electronic design automation'' (''EDA''). In mechanical design it is known as ''mechanical design automation'' (''MDA''), which includes the process of creating a technical drawing with the use of computer software. CAD software for mechanical design uses either vector-based graphics ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of California, Santa Cruz
The University of California, Santa Cruz (UC Santa Cruz or UCSC) is a public university, public Land-grant university, land-grant research university in Santa Cruz, California. It is one of the ten campuses in the University of California system. Located on Monterey Bay, on the edge of the coastal community of Santa Cruz, the campus lies on of rolling, forested hills overlooking the Pacific Ocean. Founded in 1965, UC Santa Cruz began with the intention to showcase progressive, cross-disciplinary undergraduate education, innovative teaching methods and contemporary architecture. The residential college system consists of ten small colleges that were established as a variation of the Oxbridge collegiate university system. Among the Faculty is 1 Nobel Prize Laureate, 1 Breakthrough Prize in Life Sciences recipient, 12 members from the United States National Academy of Sciences, National Academy of Sciences, 28 members of the American Academy of Arts and Sciences, and 40 members o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
VLSI
Very large-scale integration (VLSI) is the process of creating an integrated circuit (IC) by combining millions or billions of MOS transistors onto a single chip. VLSI began in the 1970s when MOS integrated circuit (Metal Oxide Semiconductor) chips were developed and then widely adopted, enabling complex semiconductor and telecommunication technologies. The microprocessor and memory chips are VLSI devices. Before the introduction of VLSI technology, most ICs had a limited set of functions they could perform. An electronic circuit might consist of a CPU, ROM, RAM and other glue logic. VLSI enables IC designers to add all of these into one chip. History Background The history of the transistor dates to the 1920s when several inventors attempted devices that were intended to control current in solid-state diodes and convert them into triodes. Success came after World War II, when the use of silicon and germanium crystals as radar detectors led to improvements in fabrication ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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