Kenneth Poss
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Kenneth Poss
Kenneth D. Poss (born 1971 in Green Bay, Wisconsin) is an American biologist and currently James B. Duke Professor of Cell Biology and director of the Regeneration Next Initiative at the Duke University School of Medicine (Durham, North Carolina). Career Poss received a B.A. in Biology from Carleton College ( Minnesota) in 1992, and a Ph.D. in Biology in 1998 from Massachusetts Institute of Technology working with Susumu Tonegawa. Poss did postdoctoral research with Mark Keating, first at University of Utah and then at Harvard Medical School. Poss became faculty in the Department of Cell Biology at Duke University in 2003. Research Poss uses zebrafish to understand how and why tissue regeneration occurs. As a postdoc, he led the first positional cloning of a gene required for regeneration of amputated fins, and he established zebrafish as a model for innate heart regeneration.  With the latter discovery, it became clear that heart regeneration occurs and is efficient in ...
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Green Bay, Wisconsin
Green Bay is a city in the U.S. state of Wisconsin. The county seat of Brown County, it is at the head of Green Bay (known locally as "the bay of Green Bay"), a sub-basin of Lake Michigan, at the mouth of the Fox River. It is above sea level and north of Milwaukee. As of the 2020 Census, Green Bay had a population of 107,395, making it the third-largest in the state of Wisconsin, after Milwaukee and Madison, and the third-largest city on Lake Michigan, after Chicago and Milwaukee. Green Bay is the principal city of the Green Bay Metropolitan Statistical Area, which covers Brown, Kewaunee, and Oconto counties. Green Bay is well known for being the home city of the National Football League (NFL)'s Green Bay Packers. History Samuel de Champlain, the founder of New France, commissioned Jean Nicolet to form a peaceful alliance with Native Americans in the western areas, whose unrest interfered with French fur trade, and to search for a shorter trade route to China throu ...
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Zebrafish
The zebrafish (''Danio rerio'') is a freshwater fish belonging to the minnow family ( Cyprinidae) of the order Cypriniformes. Native to South Asia, it is a popular aquarium fish, frequently sold under the trade name zebra danio (and thus often called a "tropical fish" although both tropical and subtropical). It is also found in private ponds. The zebrafish is an important and widely used vertebrate model organism in scientific research, for example in drug development, in particular pre-clinical development. It is also notable for its regenerative abilities, and has been modified by researchers to produce many transgenic strains. Taxonomy The zebrafish is a derived member of the genus '' Brachydanio'', of the family Cyprinidae. It has a sister-group relationship with ''Danio aesculapii''. Zebrafish are also closely related to the genus ''Devario'', as demonstrated by a phylogenetic tree of close species. Distribution Range The zebrafish is native to fresh water h ...
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American Biologists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * Ba ...
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Zebrafish Information Network
The Zebrafish Information NetworkZFIN is an online biological database of information about the zebrafish (''Danio rerio''). The zebrafish is a widely used model organism for Genetics, genetic, Genomics, genomic, and Developmental biology, developmental studies, and ZFIN provides an integrated interface for querying and displaying the large volume of data generated by this research. To facilitate use of the zebrafish as a model of human biology, ZFIN links these data to corresponding information about other model organisms (e.g., Mus musculus, mouse) and to human disease databases. Abundant links to external DNA sequence, sequence databases (e.g., GenBank) and to genome browsers are included. Gene product, gene expression, and phenotype data are annotated with terms from biomedical Ontology (computer science), ontologies. ZFIN is based at the University of Oregon in the United States, with funding provided by the National Institutes of Health (NIH). Contents ZFIN consists of two prin ...
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American Association For The Advancement Of Science
The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsibility, and supporting scientific education and science outreach for the betterment of all humanity. It is the world's largest general scientific society, with over 120,000 members, and is the publisher of the well-known scientific journal ''Science''. History Creation The American Association for the Advancement of Science was created on September 20, 1848, at the Academy of Natural Sciences in Philadelphia, Pennsylvania. It was a reformation of the Association of American Geologists and Naturalists. The society chose William Charles Redfield as their first president because he had proposed the most comprehensive plans for the organization. According to the first constitution which was agreed to at the September 20 meeting, the goal of ...
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American Heart Association
The American Heart Association (AHA) is a nonprofit organization in the United States that funds cardiovascular medical research, educates consumers on healthy living and fosters appropriate cardiac care in an effort to reduce disability and deaths caused by cardiovascular disease and stroke. Originally formed in New York City in 1924, it is currently headquartered in Dallas, Texas. The American Heart Association is a national voluntary health agency. They are known for publishinguidelineson cardiovascular disease and prevention, standards on basic life support, advanced cardiac life support (ACLS), and pediatric advanced life support (PALS), and in 2014 issued its first guidelines for preventing strokes in women. They are known also for operating a number of highly visible public service campaigns starting in the 1970s, and also operate a number of fundraising events. In 1994, the ''Chronicle of Philanthropy'', an industry publication, released a study that showed the American H ...
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Howard Hughes Medical Institute
The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, film director, and philanthropist, known during his lifetime as one of the most financially successful individuals in the world. It is one of the largest private funding organizations for biological and medical research in the United States. HHMI spends about $1 million per HHMI Investigator per year, which amounts to annual investment in biomedical research of about $825 million. The institute has an endowment of $22.6 billion, making it the second-wealthiest philanthropic organization in the United States and the second-best endowed medical research foundation in the world. HHMI is the former owner of the Hughes Aircraft Company – an American aerospace firm which was divested to various firms over time. History The institute was fo ...
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Pew Scholar
The Pew Charitable Trusts is an independent non-profit, non-governmental organization (NGO), founded in 1948. With over 6 billion in assets, its stated mission is to serve the public interest by "improving public policy, informing the public, and invigorating civic life". History The Trusts was established by the merging of several charitable funds that had been established between 1948 and 1979. The original funds were created by J. Howard Pew, Mary Ethel Pew, Joseph N. Pew Jr., and Mabel Pew Myrin—the adult sons and daughters of Sun Oil Company founder Joseph N. Pew and his wife, Mary Anderson Pew. Honoring their parents' religious conviction that good works should be done quietly, the original Pew Memorial Foundation was a grantmaking organization that made donations anonymously. The foundation became the Pew Memorial Trust in 1956, based in Philadelphia, the donors' hometown. Between 1957 and 1979, six other trusts were created, representing the personal and complementary ...
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Helen Hay Whitney Foundation
The Helen Hay Whitney Foundation, established in New York in 1943 by Joan Whitney Payson in cooperation with the estate planning of her mother, Helen Hay Whitney (1875–1944), awards the "Helen Hay Whitney Postdoctoral Fellowship" for support postdoctoral research in the biomedical sciences. Currently the Foundation awards 20 fellowships per year. The award is one of four highly competitive postdoctoral awards in the life sciences,''JCC Fund Newsletter'', 2007. and many of North America's leading scientists and medical researchers were supported in the early stages of their career by the Whitney Foundation. Members of the Scientific Advisory Committee have included: * Barbara Meyer * Erin O'Shea * Matthew Scharff * Daniel Kahne * Thomas Jessell * Stephen C. Harrison * Julie Theriot * Jonathan Weissman * S. Lawrence Zipursky Notable fellows have included: * Eric J. Ackerman * David Agard * Ronald A. Albright * David J. Anderson * Karen M. Arndt * Cornelia Bargmann * Marga ...
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Brainbow
Brainbow is a process by which individual neurons in the brain can be distinguished from neighboring neurons using fluorescent proteins. By randomly expressing different ratios of red, green, and blue derivatives of green fluorescent protein in individual neurons, it is possible to flag each neuron with a distinctive color. This process has been a major contribution to the field of neural connectomics. The technique was originally developed in 2007 by a team led by Jeff W. Lichtman and Joshua R. Sanes, both at Harvard University. The original technique has recently been adapted for use with other model research organisms including the fruit fly (''Drosophila melanogaster'')'','' zebrafish (''Danio rerio'')'','' and ''Arabidopsis thaliana''. While earlier labeling techniques allowed for the mapping of only a few neurons, this new method allows more than 100 differently mapped neurons to be simultaneously and differentially illuminated in this manner. This leads to its characteri ...
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Tissue Regeneration
In biology, regeneration is the process of renewal, restoration, and tissue growth that makes genomes, cells, organisms, and ecosystems resilient to natural fluctuations or events that cause disturbance or damage. Every species is capable of regeneration, from bacteria to humans. Regeneration can either be complete where the new tissue is the same as the lost tissue, or incomplete where after the necrotic tissue comes fibrosis. At its most elementary level, regeneration is mediated by the molecular processes of gene regulation and involves the cellular processes of cell proliferation, morphogenesis and cell differentiation. Regeneration in biology, however, mainly refers to the morphogenic processes that characterize the phenotypic plasticity of traits allowing multi-cellular organisms to repair and maintain the integrity of their physiological and morphological states. Above the genetic level, regeneration is fundamentally regulated by asexual cellular processes. Regeneration i ...
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Duke University
Duke University is a private research university in Durham, North Carolina. Founded by Methodists and Quakers in the present-day city of Trinity in 1838, the school moved to Durham in 1892. In 1924, tobacco and electric power industrialist James Buchanan Duke established The Duke Endowment and the institution changed its name to honor his deceased father, Washington Duke. The campus spans over on three contiguous sub-campuses in Durham, and a marine lab in Beaufort. The West Campus—designed largely by architect Julian Abele, an African American architect who graduated first in his class at the University of Pennsylvania School of Design—incorporates Gothic architecture with the Duke Chapel at the campus' center and highest point of elevation, is adjacent to the Medical Center. East Campus, away, home to all first-years, contains Georgian-style architecture. The university administers two concurrent schools in Asia, Duke-NUS Medical School in Singapore (established in ...
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