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Kathrin Jansen
Kathrin U. Jansen (born 1958) is the former Head of Vaccine Research and Development at Pfizer. She previously led the development of the HPV vaccine (Gardasil) and newer versions of the pneumococcal conjugate vaccine (Prevnar), and is working with BioNTech to create a COVID-19 vaccine using mRNA (Pfizer–BioNTech COVID-19 vaccine) that was approved for Emergency Use Authorization in the United States on December 11, 2020. Early life and education Jansen was born in Erfurt, East Germany. She was frequently unwell as a child, and suffered several throat infections. The medical treatment she received from her father (antibiotics, codeine) inspired her to pursue a career in drug development. Her family fled to West Germany before the Berlin Wall was constructed in 1961. To transport Jansen across the border, her aunt pretended that she was her child, giving her some sleeping pills so that she didn't wake up and tell the border patrol the truth. Her family settled in Marl, North Rhi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Marburg
The Philipps University of Marburg (german: Philipps-Universität Marburg) was founded in 1527 by Philip I, Landgrave of Hesse, which makes it one of Germany's oldest universities and the oldest still operating Protestant university in the world. It is now a public university of the state of Hesse, without religious affiliation. The University of Marburg has about 23,500 students and 7,500 employees and is located in Marburg, a town of 76,000 inhabitants, with university buildings dotted in or around the town centre. About 14 per cent of the students are international, the highest percentage in Hesse. It offers an International summer university programme and offers student exchanges through the Erasmus programme. History In 1609, the University of Marburg established the world's first professorship in chemistry. In 2012 it opened the first German interactive chemistry museum, called '. Its experimental course programme is aimed at encouraging young people to pursue careers in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pfizer–BioNTech COVID-19 Vaccine
The Pfizer–BioNTech COVID-19 vaccine ( INN: tozinameran), sold under the brand name Comirnaty, is an mRNA-based COVID-19 vaccine developed by the German biotechnology company BioNTech. For its development, BioNTech collaborated with American company Pfizer to carry out clinical trials, logistics, and manufacturing. It is authorized for use in people aged five years and older in some jurisdictions, twelve years and older in some jurisdictions, and for people sixteen years and older in other jurisdictions, to provide protection against COVID-19, caused by infection with the SARS-CoV-2 virus. The vaccine is given by intramuscular injection. It is composed of nucleoside-modified mRNA (modRNA) encoding a mutated form of the full-length spike protein of SARS-CoV-2, which is encapsulated in lipid nanoparticles. Initial advice indicated that vaccination required two doses given 21 days apart, but the interval was later extended to up to 42 days in the US, and up to four months i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Papillomavirus Infection
Human papillomavirus infection (HPV infection) is caused by a DNA virus from the ''Papillomaviridae'' family. Many HPV infections cause no symptoms and 90% resolve spontaneously within two years. In some cases, an HPV infection persists and results in either warts or precancerous lesions. These lesions, depending on the site affected, increase the risk of cancer of the cervix, vulva, vagina, penis, anus, mouth, tonsils, or throat. Nearly all cervical cancer is due to HPV and two strains – HPV16 and HPV18 – account for 70% of cases. HPV16 is responsible for almost 90% of HPV-positive oropharyngeal cancers. Between 60% and 90% of the other cancers listed above are also linked to HPV. HPV6 and HPV11 are common causes of genital warts and laryngeal papillomatosis. An HPV infection is caused by ''human papillomavirus'', a DNA virus from the papillomavirus family. Over 170 types have been described. An individual can become infected with more than one type of HPV, and the disea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States
The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territories, nine Minor Outlying Islands, and 326 Indian reservations. The United States is also in free association with three Pacific Island sovereign states: the Federated States of Micronesia, the Marshall Islands, and the Republic of Palau. It is the world's third-largest country by both land and total area. It shares land borders with Canada to its north and with Mexico to its south and has maritime borders with the Bahamas, Cuba, Russia, and other nations. With a population of over 333 million, it is the most populous country in the Americas and the third most populous in the world. The national capital of the United States is Washington, D.C. and its most populous city and principal financial center is New York City. Paleo-Americ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Baculoviridae
''Baculoviridae'' is a family of viruses. Arthropods, among the most studied being Lepidoptera, Hymenoptera and Diptera, serve as natural hosts. Currently, 85 species are placed in this family, assigned to four genera. Baculoviruses are known to infect insects, with over 600 host species having been described. Immature (larval) forms of lepidopteran species (moths and butterflies) are the most common hosts, but these viruses have also been found infecting sawflies, and mosquitoes. Although baculoviruses are capable of entering mammalian cells in culture, they are not known to be capable of replication in mammalian or other vertebrate animal cells. Starting in the 1940s, they were used and studied widely as biopesticides in crop fields. Baculoviruses contain a circular, double-stranded DNA (dsDNA) genome ranging from 80 to 180 kbp. Historical influence The earliest records of baculoviruses can be found in the literature from as early as the 16th century in reports of "wilting ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Oxford
, mottoeng = The Lord is my light , established = , endowment = £6.1 billion (including colleges) (2019) , budget = £2.145 billion (2019–20) , chancellor = The Lord Patten of Barnes , vice_chancellor = Louise Richardson , students = 24,515 (2019) , undergrad = 11,955 , postgrad = 12,010 , other = 541 (2017) , city = Oxford , country = England , coordinates = , campus_type = University town , athletics_affiliations = Blue (university sport) , logo_size = 250px , website = , logo = University of Oxford.svg , colours = Oxford Blue , faculty = 6,995 (2020) , academic_affiliations = , The University of Oxford is a collegiate research university in Oxf ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immunoglobulin E
Immunoglobulin E (IgE) is a type of antibody (or immunoglobulin (Ig) " isotype") that has been found only in mammals. IgE is synthesised by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing four Ig-like constant domains (Cε1–Cε4). IgE is thought to be an important part of the immune response against infection by certain parasitic worms, including ''Schistosoma mansoni'', ''Trichinella spiralis'', and ''Fasciola hepatica''. IgE is also utilized during immune defense against certain protozoan parasites such as ''Plasmodium falciparum''. IgE may have evolved as a defense to protect against venoms. IgE also has an essential role in type I hypersensitivity, which manifests in various allergic diseases, such as allergic asthma, most types of sinusitis, allergic rhinitis, food allergies, and specific types of chronic urticaria and atopic dermatitis. IgE also plays a pivotal role in responses to allergens, such as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Geneva
Geneva ( ; french: Genève ) frp, Genèva ; german: link=no, Genf ; it, Ginevra ; rm, Genevra is the List of cities in Switzerland, second-most populous city in Switzerland (after Zürich) and the most populous city of Romandy, the French-speaking part of Switzerland. Situated in the south west of the country, where the Rhône exits Lake Geneva, it is the capital of the Canton of Geneva, Republic and Canton of Geneva. The city of Geneva () had a population 201,818 in 2019 (Jan. estimate) within its small municipal territory of , but the Canton of Geneva (the city and its closest Swiss suburbs and exurbs) had a population of 499,480 (Jan. 2019 estimate) over , and together with the suburbs and exurbs located in the canton of Vaud and in the French Departments of France, departments of Ain and Haute-Savoie the cross-border Geneva metropolitan area as officially defined by Eurostat, which extends over ,As of 2020, the Eurostat-defined Functional Urban Area of Geneva was made up of 9 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acetylcholine Receptor
An acetylcholine receptor (abbreviated AChR) is an integral membrane protein that responds to the binding of acetylcholine, a neurotransmitter. Classification Like other transmembrane receptors, acetylcholine receptors are classified according to their "pharmacology," or according to their relative affinities and sensitivities to different molecules. Although all acetylcholine receptors, by definition, respond to acetylcholine, they respond to other molecules as well. *Nicotinic acetylcholine receptors (''nAChR'', also known as "ionotropic" acetylcholine receptors) are particularly responsive to nicotine. The nicotine ACh receptor is also a Na+, K+ and Ca2+ ion channel. *Muscarinic acetylcholine receptors (''mAChR'', also known as "metabotropic" acetylcholine receptors) are particularly responsive to muscarine. Nicotinic and muscarinic are two main kinds of "cholinergic" receptors. Receptor types Molecular biology has shown that the nicotinic and muscarinic receptors belong ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alexander Von Humboldt Foundation
The Alexander von Humboldt Foundation (german: Alexander von Humboldt-Stiftung) is a foundation established by the government of the Federal Republic of Germany and funded by the Federal Foreign Office, the Federal Ministry of Education and Research, the Federal Ministry for Economic Cooperation and Development as well as other national and international partners; it promotes international academic cooperation between excellent scientists and scholars from Germany and from abroad. Description Every year, the Foundation grants more than 700 competitive research fellowships and awards, primarily going to academics from natural sciences (mathematics included) and the humanities. It allows scientists and scholars from all over the world to come to Germany to work on a research project they have chosen themselves together with a host and collaborative partner. Additionally it funds German scholars' via the Feodor Lynen Fellowships to go anywhere in the world to work on a research proj ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marl, North Rhine-Westphalia
Marl () is a town and a municipality in the Recklinghausen (district), district of Recklinghausen, in North Rhine-Westphalia, Germany. It is situated near the Wesel-Datteln Canal, approx. 10 km north-west of Recklinghausen. It has about 90,000 people. Geography Location The town adjoins in the north to the woodlands of the Haard and the natural park Hohe Mark. The town forms the smooth transition between the industrial Ruhr, ''Ruhrgebiet'' and the rural ''Münsterland''. The northern town border coincides nearly completely with the course of the river Lippe river, Lippe. Approximately 60% of the total town area are fields, woods, watercourses, parks and other green areas. Town area Marl has the following urban districts: Neighbour towns In the north Marl adjoins to Haltern, Haltern am See, in the east to Oer-Erkenschwick, in the southeast to Recklinghausen, in the south to Herten, in the southwest to Gelsenkirchen and in the west to Dorsten. Nature reserves * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Berlin Wall
The Berlin Wall (german: Berliner Mauer, ) was a guarded concrete barrier that encircled West Berlin from 1961 to 1989, separating it from East Berlin and East Germany (GDR). Construction of the Berlin Wall was commenced by the government of the GDR on 13 August 1961. It included guard towers placed along large concrete walls, accompanied by a wide area (later known as the "death strip") that contained anti-vehicle trenches, beds of nails and other defenses. The Eastern Bloc portrayed the Wall as protecting its population from fascist elements conspiring to prevent the "will of the people" from building a socialist state in the GDR. The authorities officially referred to the Berlin Wall as the ''Anti-Fascist Protection Rampart'' (german: Antifaschistischer Schutzwall, ). The West Berlin city government sometimes referred to it as the "Wall of Shame", a term coined by mayor Willy Brandt in reference to the Wall's restriction on freedom of movement. Along with the separat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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